4MQ9
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![BU of 4mq9 by Molmil](/molmil-images/mine/4mq9) | Crystal structure of Thermus thermophilus RNA polymerase holoenzyme in complex with GE23077 | 分子名称: | (2Z)-2-methylbut-2-enoic acid, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Ho, M.X, Arnold, E, Ebright, R.H, Zhang, Y, Tuske, S. | 登録日 | 2013-09-16 | 公開日 | 2014-05-07 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.35 Å) | 主引用文献 | GE23077 binds to the RNA polymerase 'i' and 'i+1' sites and prevents the binding of initiating nucleotides. Elife, 3, 2014
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3LZD
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![BU of 3lzd by Molmil](/molmil-images/mine/3lzd) | Crystal structure of Dph2 from Pyrococcus horikoshii with 4Fe-4S cluster | 分子名称: | Dph2, IRON/SULFUR CLUSTER, SULFATE ION | 著者 | Torelli, A.T, Zhang, Y, Zhu, X, Lee, M, Dzikovski, B, Koralewski, R.M, Wang, E, Freed, J, Krebs, C, Lin, H, Ealick, S.E. | 登録日 | 2010-03-01 | 公開日 | 2010-07-14 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Diphthamide biosynthesis requires an organic radical generated by an iron-sulphur enzyme. Nature, 465, 2010
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5WTA
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![BU of 5wta by Molmil](/molmil-images/mine/5wta) | Crystal Structure of Staphylococcus aureus SdrE apo form | 分子名称: | Serine-aspartate repeat-containing protein E | 著者 | Wu, M, Zhang, Y, Hang, T, Wang, C, Yang, Y, Zang, J, Zhang, M, Zhang, X. | 登録日 | 2016-12-10 | 公開日 | 2017-07-19 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Staphylococcus aureus SdrE captures complement factor H's C-terminus via a novel 'close, dock, lock and latch' mechanism for complement evasion Biochem. J., 474, 2017
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5WTB
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![BU of 5wtb by Molmil](/molmil-images/mine/5wtb) | Complex Structure of Staphylococcus aureus SdrE with human complement factor H | 分子名称: | Peptide from Complement factor H, Serine-aspartate repeat-containing protein E | 著者 | Wu, M, Zhang, Y, Hang, T, Wang, C, Yang, Y, Zang, J, Zhang, M, Zhang, X. | 登録日 | 2016-12-10 | 公開日 | 2017-07-19 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Staphylococcus aureus SdrE captures complement factor H's C-terminus via a novel 'close, dock, lock and latch' mechanism for complement evasion Biochem. J., 474, 2017
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7T1F
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![BU of 7t1f by Molmil](/molmil-images/mine/7t1f) | |
5WMD
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![BU of 5wmd by Molmil](/molmil-images/mine/5wmd) | N-terminal bromodomain of BRD4 in complex with OTX-015 | 分子名称: | 2-[(6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl]-N-(4-hydroxyphenyl)acetamide, Bromodomain-containing protein 4 | 著者 | Zhang, Y. | 登録日 | 2017-07-28 | 公開日 | 2018-08-01 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.27 Å) | 主引用文献 | BRD4 Profiling Identifies Critical Chronic Lymphocytic Leukemia Oncogenic Circuits and Reveals Sensitivity to PLX51107, a Novel Structurally Distinct BET Inhibitor. Cancer Discov, 8, 2018
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5WMG
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![BU of 5wmg by Molmil](/molmil-images/mine/5wmg) | N-terminal bromodomain of BRD4 in complex with OTX-015 | 分子名称: | 1,2-ETHANEDIOL, 4-{6-(3,5-dimethyl-1,2-oxazol-4-yl)-1-[(1S)-1-(pyridin-2-yl)ethyl]-1H-pyrrolo[3,2-b]pyridin-3-yl}benzoic acid, Bromodomain-containing protein 4 | 著者 | Zhang, Y. | 登録日 | 2017-07-28 | 公開日 | 2018-08-01 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.19 Å) | 主引用文献 | BRD4 Profiling Identifies Critical Chronic Lymphocytic Leukemia Oncogenic Circuits and Reveals Sensitivity to PLX51107, a Novel Structurally Distinct BET Inhibitor. Cancer Discov, 8, 2018
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5WMA
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![BU of 5wma by Molmil](/molmil-images/mine/5wma) | N-terminal bromodomain of BRD4 in complex with PLX5981 | 分子名称: | 1,2-ETHANEDIOL, 5-(3,5-dimethyl-1,2-oxazol-4-yl)-1H-pyrrolo[2,3-b]pyridine, Bromodomain-containing protein 4 | 著者 | Zhang, Y. | 登録日 | 2017-07-28 | 公開日 | 2018-08-01 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.401 Å) | 主引用文献 | BRD4 Profiling Identifies Critical Chronic Lymphocytic Leukemia Oncogenic Circuits and Reveals Sensitivity to PLX51107, a Novel Structurally Distinct BET Inhibitor. Cancer Discov, 8, 2018
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7Q83
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3CIV
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6WXK
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![BU of 6wxk by Molmil](/molmil-images/mine/6wxk) | PHF23 PHD Domain Apo | 分子名称: | PHD finger protein 23, ZINC ION | 著者 | Vann, K.R, Zhang, J, Zhang, Y, Kutateladze, T. | 登録日 | 2020-05-11 | 公開日 | 2020-07-15 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Mechanistic insights into chromatin targeting by leukemic NUP98-PHF23 fusion. Nat Commun, 11, 2020
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4GA3
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![BU of 4ga3 by Molmil](/molmil-images/mine/4ga3) | Crystal Structure of Human Farnesyl Diphosphate Synthase in Complex with BPH-1260 | 分子名称: | 1-butyl-3-(2-hydroxy-2,2-diphosphonoethyl)-1H-imidazol-3-ium, Farnesyl pyrophosphate synthase, MAGNESIUM ION, ... | 著者 | Liu, Y.-L, Zhang, Y, Oldfield, E. | 登録日 | 2012-07-24 | 公開日 | 2013-05-08 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | 主引用文献 | Chemo-Immunotherapeutic Anti-Malarials Targeting Isoprenoid Biosynthesis. ACS MED.CHEM.LETT., 4, 2013
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4HS4
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![BU of 4hs4 by Molmil](/molmil-images/mine/4hs4) | Crystal structure of a putative chromate reductase from Gluconacetobacter hansenii, Gh-ChrR, containing a Y129N substitution. | 分子名称: | Chromate reductase, FLAVIN MONONUCLEOTIDE | 著者 | Zhang, Y, Robinson, H, Buchko, G.W. | 登録日 | 2012-10-29 | 公開日 | 2012-12-26 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Mechanistic insights of chromate and uranyl reduction by the NADPH-dependent FMN reductase, ChrR, from Gluconacetobacter hansenii To be Published
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4H6P
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![BU of 4h6p by Molmil](/molmil-images/mine/4h6p) | Crystal structure of a putative chromate reductase from Gluconacetobacter hansenii, Gh-ChrR, containing a R101A substitution. | 分子名称: | Chromate reductase, FLAVIN MONONUCLEOTIDE | 著者 | Zhang, Y, Robinson, H, Buchko, G.W. | 登録日 | 2012-09-19 | 公開日 | 2012-10-10 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.556 Å) | 主引用文献 | Mechanistic insights of chromate and uranyl reduction by the NADPH-dependent FMN reductase, ChrR, from Gluconacetobacter hansenii To be Published
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8GUG
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![BU of 8gug by Molmil](/molmil-images/mine/8gug) | Structure of VPA0770 toxin bound to VPA0769 antitoxin in Vibrio parahaemolyticus | 分子名称: | DUF2384 domain-containing protein, RES domain-containing protein | 著者 | Song, X.J, Zhang, Y, Xu, Y.Y, Lin, Z. | 登録日 | 2022-09-12 | 公開日 | 2023-07-26 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Structural insights of the toxin-antitoxin system VPA0770-VPA0769 in Vibrio parahaemolyticus. Int.J.Biol.Macromol., 242, 2023
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6C00
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1AOG
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5Y4O
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![BU of 5y4o by Molmil](/molmil-images/mine/5y4o) | Cryo-EM structure of MscS channel, YnaI | 分子名称: | Low conductance mechanosensitive channel YnaI | 著者 | Zhang, Y, Yu, J. | 登録日 | 2017-08-04 | 公開日 | 2019-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | A binding-block ion selective mechanism revealed by a Na/K selective channel. Protein Cell, 9, 2018
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5E18
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6URG
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![BU of 6urg by Molmil](/molmil-images/mine/6urg) | Cryo-EM structure of human CPSF160-WDR33-CPSF30-CPSF100 PIM complex | 分子名称: | Cleavage and polyadenylation specificity factor subunit 1, Cleavage and polyadenylation specificity factor subunit 2, Cleavage and polyadenylation specificity factor subunit 4, ... | 著者 | Sun, Y, Zhang, Y, Walz, T, Tong, L. | 登録日 | 2019-10-23 | 公開日 | 2019-11-27 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural Insights into the Human Pre-mRNA 3'-End Processing Machinery. Mol.Cell, 77, 2020
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6URO
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![BU of 6uro by Molmil](/molmil-images/mine/6uro) | Cryo-EM structure of human CPSF160-WDR33-CPSF30-PAS RNA-CstF77 complex | 分子名称: | Cleavage and polyadenylation specificity factor subunit 1, Cleavage and polyadenylation specificity factor subunit 4, Cleavage stimulation factor subunit 3, ... | 著者 | Sun, Y, Zhang, Y, Walz, T, Tong, L. | 登録日 | 2019-10-23 | 公開日 | 2019-11-27 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structural Insights into the Human Pre-mRNA 3'-End Processing Machinery. Mol.Cell, 77, 2020
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8E4V
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5XS9
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8AEY
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![BU of 8aey by Molmil](/molmil-images/mine/8aey) | 3 A CRYO-EM STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS FERRITIN FROM TIMEPIX3 detector | 分子名称: | Ferritin BfrB | 著者 | Zhang, Y, van Schayck, J.P, Knoops, K, Peters, P.J, Ravelli, R.B.G. | 登録日 | 2022-07-14 | 公開日 | 2023-01-18 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | 主引用文献 | Integration of an Event-driven Timepix3 Hybrid Pixel Detector into a Cryo-EM Workflow Microsc Microanal, 2023
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5HMC
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![BU of 5hmc by Molmil](/molmil-images/mine/5hmc) | Crystal structure of S. sahachiroi AziG complexed with 5-methyl naphthoic acid | 分子名称: | 5-methylnaphthalene-1-carboxylic acid, Azi13, SULFATE ION | 著者 | Zhang, Y, Erb, M.S, Ealick, S.E. | 登録日 | 2016-01-15 | 公開日 | 2016-02-03 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Polyketide Ring Expansion Mediated by a Thioesterase, Chain Elongation and Cyclization Domain, in Azinomycin Biosynthesis: Characterization of AziB and AziG. Biochemistry, 55, 2016
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