7D03
| S protein of SARS-CoV-2 in complex bound with FabP5A-2G7 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, IGL c2312_light_IGLV2-14_IGLJ2,IGL@ protein, ... | 著者 | Yan, R.H, Zhang, Y.Y, Li, Y.N, Zhou, Q. | 登録日 | 2020-09-09 | 公開日 | 2021-03-10 | 最終更新日 | 2021-05-19 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural basis for bivalent binding and inhibition of SARS-CoV-2 infection by human potent neutralizing antibodies. Cell Res., 31, 2021
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7D0D
| S protein of SARS-CoV-2 in complex bound with P5A-3C12_2B | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of P5A-3C12, ... | 著者 | Yan, R.H, Wang, R.K, Ju, B, Yu, J.F, Zhang, Y.Y, Liu, N, Wang, H.W, Wang, X.Q, Zhang, L.Q, Zhou, Q. | 登録日 | 2020-09-09 | 公開日 | 2021-03-10 | 最終更新日 | 2021-05-19 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structural basis for bivalent binding and inhibition of SARS-CoV-2 infection by human potent neutralizing antibodies. Cell Res., 31, 2021
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4ZV8
| Structure of CYP2B6 (Y226H/K262R) with additional mutation Y244W in complex with alpha-Pinene | 分子名称: | (+)-alpha-Pinene, 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE, Cytochrome P450 2B6, ... | 著者 | Liu, J, Shah, M.B, Stout, C.D, Halpert, J.R. | 登録日 | 2015-05-18 | 公開日 | 2016-03-30 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | 主引用文献 | Coumarin Derivatives as Substrate Probes of Mammalian Cytochromes P450 2B4 and 2B6: Assessing the Importance of 7-Alkoxy Chain Length, Halogen Substitution, and Non-Active Site Mutations. Biochemistry, 55, 2016
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7YV4
| Crystal structure of human UCHL3 in complex with Farrerol | 分子名称: | (2~{S})-2-(4-hydroxyphenyl)-6,8-dimethyl-5,7-bis(oxidanyl)-2,3-dihydrochromen-4-one, Ubiquitin carboxyl-terminal hydrolase isozyme L3 | 著者 | Mao, Z.Y, Xu, X.J, Zhang, W.T. | 登録日 | 2022-08-18 | 公開日 | 2023-04-19 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | 主引用文献 | Farrerol directly activates the deubiqutinase UCHL3 to promote DNA repair and reprogramming when mediated by somatic cell nuclear transfer. Nat Commun, 14, 2023
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7CZ6
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7D0L
| The major capsid of Omono River virus (strain:LZ), protrusion-free status. | 分子名称: | Capsid protein | 著者 | Shao, Q, Jia, X, Gao, Y, Liu, Z. | 登録日 | 2020-09-11 | 公開日 | 2021-03-03 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.95 Å) | 主引用文献 | Cryo-EM reveals a previously unrecognized structural protein of a dsRNA virus implicated in its extracellular transmission. Plos Pathog., 17, 2021
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7D0K
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2GA2
| h-MetAP2 complexed with A193400 | 分子名称: | 5-BROMO-2-{[(4-CHLOROPHENYL)SULFONYL]AMINO}BENZOIC ACID, MANGANESE (II) ION, Methionine aminopeptidase 2 | 著者 | Park, C. | 登録日 | 2006-03-07 | 公開日 | 2007-03-13 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Development of sulfonamide compounds as potent methionine aminopeptidase type II inhibitors with antiproliferative properties. Bioorg.Med.Chem.Lett., 16, 2006
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7D3Y
| Crystal structure of the osPHR2-osSPX2 complex | 分子名称: | INOSITOL HEXAKISPHOSPHATE, Protein PHOSPHATE STARVATION RESPONSE 2, SPX domain-containing protein 2,Isoform 1 of Core histone macro-H2A.1 | 著者 | Zhang, Q.X, Guan, Z.Y, Zuo, J.Q, Zhang, Z.F, Liu, Z. | 登録日 | 2020-09-21 | 公開日 | 2021-10-06 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.11 Å) | 主引用文献 | Mechanistic insights into the regulation of plant phosphate homeostasis by the rice SPX2 - PHR2 complex. Nat Commun, 13, 2022
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4PZA
| The complex structure of mycobacterial glucosyl-3-phosphoglycerate phosphatase Rv2419c with inorganic phosphate | 分子名称: | Glucosyl-3-phosphoglycerate phosphatase, PHOSPHATE ION | 著者 | Zhou, W.H, Zheng, Q.Q, Jiang, D.Q, Zhang, W, Zhang, Q.Q, Jin, J, Li, X, Yang, H.T, Shaw, N, Rao, Z. | 登録日 | 2014-03-29 | 公開日 | 2014-06-11 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.776 Å) | 主引用文献 | Mechanism of dephosphorylation of glucosyl-3-phosphoglycerate by a histidine phosphatase J.Biol.Chem., 289, 2014
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4PZ9
| The native structure of mycobacterial glucosyl-3-phosphoglycerate phosphatase Rv2419c | 分子名称: | Glucosyl-3-phosphoglycerate phosphatase | 著者 | Zhou, W.H, Zheng, Q.Q, Jiang, D.Q, Zhang, W, Zhang, Q.Q, Jin, J, Li, X, Yang, H.T, Shaw, N, Rao, Z. | 登録日 | 2014-03-28 | 公開日 | 2014-06-11 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | Mechanism of dephosphorylation of glucosyl-3-phosphoglycerate by a histidine phosphatase J.Biol.Chem., 289, 2014
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7D3T
| Crystal structure of OSPHR2 in complex with DNA | 分子名称: | DNA (5'-D(P*CP*TP*CP*GP*GP*AP*TP*AP*TP*CP*CP*TP*CP*AP*AP*G)-3'), DNA (5'-D(P*GP*CP*TP*TP*GP*AP*GP*GP*AP*TP*AP*TP*CP*CP*GP*A)-3'), Protein PHOSPHATE STARVATION RESPONSE 2 | 著者 | Guan, Z.Y, Zhang, Z.F, Liu, Z. | 登録日 | 2020-09-20 | 公開日 | 2021-10-06 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Mechanistic insights into the regulation of plant phosphate homeostasis by the rice SPX2 - PHR2 complex. Nat Commun, 13, 2022
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4QIH
| The structure of mycobacterial glucosyl-3-phosphoglycerate phosphatase Rv2419c complexes with VO3 | 分子名称: | Glucosyl-3-phosphoglycerate phosphatase, VANADATE ION | 著者 | Zhou, W.H, Zheng, Q.Q, Jiang, D.Q, Zhang, W, Zhang, Q.Q, Jin, J, Li, X, Yang, H.T, Shaw, N, Rao, Z. | 登録日 | 2014-05-30 | 公開日 | 2014-06-11 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.299 Å) | 主引用文献 | Mechanism of dephosphorylation of glucosyl-3-phosphoglycerate by a histidine phosphatase J.Biol.Chem., 289, 2014
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5I9F
| Crystal structure of designed pentatricopeptide repeat protein dPPR-U10 in complex with its target RNA U10 | 分子名称: | RNA (5'-R(*GP*GP*GP*GP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*CP*CP*CP*C)-3'), pentatricopeptide repeat protein dPPR-U10 | 著者 | Shen, C, Zhang, D, Guan, Z, Zou, T, Yin, Y. | 登録日 | 2016-02-20 | 公開日 | 2016-04-27 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.194 Å) | 主引用文献 | Structural basis for specific single-stranded RNA recognition by designer pentatricopeptide repeat proteins. Nat Commun, 7, 2016
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4IGP
| Histone H3 Lysine 4 Demethylating Rice JMJ703 apo enzyme | 分子名称: | FE (III) ION, Os05g0196500 protein | 著者 | Chen, Q.F, Chen, X.S, Wang, Q, Zhang, F.B, Lou, Z.Y, Zhang, Q.F, Zhou, D.X. | 登録日 | 2012-12-17 | 公開日 | 2013-04-03 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.003 Å) | 主引用文献 | Structural basis of a histone H3 lysine 4 demethylase required for stem elongation in rice. PLoS Genet., 9, 2013
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4IGO
| Histone H3 Lysine 4 Demethylating rice Rice JMJ703 in complex with alpha-KG | 分子名称: | 2-OXOGLUTARIC ACID, FE (III) ION, Os05g0196500 protein | 著者 | Chen, Q.F, Chen, X.S, Wang, Q, Zhang, F.B, Lou, Z.Y, Zhang, Q.F, Zhou, D.X. | 登録日 | 2012-12-17 | 公開日 | 2013-04-03 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural basis of a histone H3 lysine 4 demethylase required for stem elongation in rice. PLoS Genet., 9, 2013
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4IGQ
| Histone H3 Lysine 4 Demethylating Rice JMJ703 in complex with methylated H3K4 substrate | 分子名称: | FE (III) ION, N-OXALYLGLYCINE, Os05g0196500 protein, ... | 著者 | Chen, Q.F, Chen, X.S, Wang, Q, Zhang, F.B, Lou, Z.Y, Zhang, Q.F, Zhou, D.X. | 登録日 | 2012-12-17 | 公開日 | 2013-04-03 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Structural basis of a histone H3 lysine 4 demethylase required for stem elongation in rice. PLoS Genet., 9, 2013
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4QEI
| Two distinct conformational states of GlyRS captured in crystal lattice | 分子名称: | ADENOSINE MONOPHOSPHATE, Glycine--tRNA ligase, tRNA-Gly-CCC-2-2 | 著者 | Xie, W, Qin, X, Deng, X, Zhang, Q, Li, Q. | 登録日 | 2014-05-16 | 公開日 | 2015-05-20 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.875 Å) | 主引用文献 | Large Conformational Changes of Insertion 3 in Human Glycyl-tRNA Synthetase (hGlyRS) during Catalysis J.Biol.Chem., 291, 2016
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4WD9
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5DDS
| Crystal structure of aminotransferase CrmG from Actinoalloteichus sp. WH1-2216-6 in complex with PLP | 分子名称: | ACETIC ACID, CrmG, GLYCEROL, ... | 著者 | Xu, J, Feng, Z, Liu, J. | 登録日 | 2015-08-25 | 公開日 | 2016-08-10 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Biochemical and Structural Insights into the Aminotransferase CrmG in Caerulomycin Biosynthesis Acs Chem.Biol., 11, 2016
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5DDW
| Crystal structure of aminotransferase CrmG from Actinoalloteichus sp. WH1-2216-6 in complex with the PMP external aldimine adduct with Caerulomycin M | 分子名称: | CrmG, GLYCEROL, [5-hydroxy-4-({(E)-[(4-hydroxy-2,2'-bipyridin-6-yl)methylidene]amino}methyl)-6-methylpyridin-3-yl]methyl dihydrogen phosphate | 著者 | Xu, J, Feng, Z, Liu, J. | 登録日 | 2015-08-25 | 公開日 | 2016-08-10 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Biochemical and Structural Insights into the Aminotransferase CrmG in Caerulomycin Biosynthesis Acs Chem.Biol., 11, 2016
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5DDU
| Crystal structure of aminotransferase CrmG from Actinoalloteichus sp. WH1-2216-6 in complex with PMP | 分子名称: | 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, CrmG, GLYCEROL, ... | 著者 | Xu, J, Feng, Z, Liu, J. | 登録日 | 2015-08-25 | 公開日 | 2016-08-10 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.46 Å) | 主引用文献 | Biochemical and Structural Insights into the Aminotransferase CrmG in Caerulomycin Biosynthesis Acs Chem.Biol., 11, 2016
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3KL1
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6DNE
| Crystal structure of human Bromodomain-containing protein 4 (BRD4) bromodomain with MS660 | 分子名称: | Bromodomain-containing protein 4, N,N'-[ethane-1,2-diylbis(oxyethane-2,1-diyl)]bis{2-[(6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl]acetamide} | 著者 | Ren, C, Zhou, M.M. | 登録日 | 2018-06-06 | 公開日 | 2018-07-18 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.958 Å) | 主引用文献 | Spatially constrained tandem bromodomain inhibition bolsters sustained repression of BRD4 transcriptional activity for TNBC cell growth. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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3KLX
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