4WNU
Human Cytochrome P450 2D6 Quinidine Complex
Summary for 4WNU
| Entry DOI | 10.2210/pdb4wnu/pdb |
| Related | 2F9Q 3QM4 3TBG 3TDA 4WNT 4WNV 4WNW |
| Descriptor | Cytochrome P450 2D6, PROTOPORPHYRIN IX CONTAINING FE, Quinidine, ... (7 entities in total) |
| Functional Keywords | cyp2d6, p450 2d6, cytochrome p450, monooxygenase, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 4 |
| Total formula weight | 220246.40 |
| Authors | Wang, A.,Stout, C.D.,Johnson, E.F. (deposition date: 2014-10-14, release date: 2015-01-14, Last modification date: 2023-09-27) |
| Primary citation | Wang, A.,Stout, C.D.,Zhang, Q.,Johnson, E.F. Contributions of Ionic Interactions and Protein Dynamics to Cytochrome P450 2D6 (CYP2D6) Substrate and Inhibitor Binding. J.Biol.Chem., 290:5092-5104, 2015 Cited by PubMed: 25555909DOI: 10.1074/jbc.M114.627661 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.26 Å) |
Structure validation
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