8WJY
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![BU of 8wjy by Molmil](/molmil-images/mine/8wjy) | PKMYT1_Cocrystal_Cpd 4 | 分子名称: | DIMETHYL SULFOXIDE, GLYCEROL, Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase, ... | 著者 | Wang, Y, Wang, C, Liu, T, Qi, H, Chen, S, Cai, X, Zhang, M, Aliper, A, Ren, F, Ding, X, Zhavoronkov, A. | 登録日 | 2023-09-26 | 公開日 | 2023-11-22 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | Discovery of Tetrahydropyrazolopyrazine Derivatives as Potent and Selective MYT1 Inhibitors for the Treatment of Cancer. J.Med.Chem., 67, 2024
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2O0F
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![BU of 2o0f by Molmil](/molmil-images/mine/2o0f) | Docking of the modified RF3 X-ray structure into cryo-EM map of E.coli 70S ribosome bound with RF3 | 分子名称: | Peptide chain release factor 3 | 著者 | Gao, H, Zhou, Z, Rawat, U, Huang, C, Bouakaz, L, Wang, C, Liu, Y, Zavialov, A, Gursky, R, Sanyal, S, Ehrenberg, M, Frank, J, Song, H. | 登録日 | 2006-11-27 | 公開日 | 2007-07-24 | 最終更新日 | 2023-12-27 | 実験手法 | ELECTRON MICROSCOPY (15.5 Å) | 主引用文献 | RF3 induces ribosomal conformational changes responsible for dissociation of class I release factors Cell(Cambridge,Mass.), 129, 2007
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6W8S
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![BU of 6w8s by Molmil](/molmil-images/mine/6w8s) | Crystal structure of metacaspase 4 from Arabidopsis | 分子名称: | Metacaspase-4, SULFATE ION | 著者 | Zhu, P, Yu, X.H, Wang, C, Zhang, Q, Liu, W, McSweeney, S, Shanklin, J, Lam, E, Liu, Q. | 登録日 | 2020-03-21 | 公開日 | 2020-05-20 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.484 Å) | 主引用文献 | Structural basis for Ca2+-dependent activation of a plant metacaspase. Nat Commun, 11, 2020
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6W8T
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![BU of 6w8t by Molmil](/molmil-images/mine/6w8t) | Crystal structure of metacaspase 4 from Arabidopsis (microcrystals treated with calcium) | 分子名称: | Metacaspase-4, SULFATE ION | 著者 | Zhu, P, Yu, X.H, Wang, C, Zhang, Q, Liu, W, McSweeney, S, Shanklin, J, Lam, E, Liu, Q. | 登録日 | 2020-03-21 | 公開日 | 2020-05-20 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural basis for Ca2+-dependent activation of a plant metacaspase. Nat Commun, 11, 2020
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2VGB
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![BU of 2vgb by Molmil](/molmil-images/mine/2vgb) | HUMAN ERYTHROCYTE PYRUVATE KINASE | 分子名称: | 1,6-di-O-phosphono-beta-D-fructofuranose, 2-PHOSPHOGLYCOLIC ACID, MANGANESE (II) ION, ... | 著者 | Valentini, G, Chiarelli, L, Fortin, R, Dolzan, M, Galizzi, A, Abraham, D.J, Wang, C, Bianchi, P, Zanella, A, Mattevi, A. | 登録日 | 2007-11-12 | 公開日 | 2007-11-20 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.73 Å) | 主引用文献 | Structure and Function of Human Erythrocyte Pyruvate Kinase. Molecular Basis of Nonspherocytic Hemolytic Anemia. J.Biol.Chem., 277, 2002
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5WZG
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![BU of 5wzg by Molmil](/molmil-images/mine/5wzg) | Structure of APUM23-GAAUUGACGG | 分子名称: | Pumilio homolog 23, RNA (5'-R(*GP*AP*AP*UP*UP*GP*AP*CP*GP*G)-3') | 著者 | Bao, H, Wang, N, Wang, C, Jiang, Y, Wu, J, Shi, Y. | 登録日 | 2017-01-18 | 公開日 | 2017-09-27 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Structural basis for the specific recognition of 18S rRNA by APUM23. Nucleic Acids Res., 45, 2017
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6W8R
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![BU of 6w8r by Molmil](/molmil-images/mine/6w8r) | Crystal structure of metacaspase 4 C139A from Arabidopsis | 分子名称: | Metacaspase-4, SULFATE ION | 著者 | Zhu, P, Yu, X.H, Wang, C, Zhang, Q, Liu, W, McSweeney, S, Shanklin, J, Lam, E, Liu, Q. | 登録日 | 2020-03-21 | 公開日 | 2020-05-20 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.801 Å) | 主引用文献 | Structural basis for Ca2+-dependent activation of a plant metacaspase. Nat Commun, 11, 2020
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5ERG
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![BU of 5erg by Molmil](/molmil-images/mine/5erg) | Crystal structure of the two-subunit tRNA m1A58 methyltransferase TRM6-TRM61 in complex with SAM | 分子名称: | S-ADENOSYLMETHIONINE, tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRM61, tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 | 著者 | Zhu, Y, Wang, M, Wang, C, Fan, X, Jiang, X, Teng, M, Li, X. | 登録日 | 2015-11-14 | 公開日 | 2016-09-14 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.202 Å) | 主引用文献 | Crystal structure of the two-subunit tRNA m(1)A58 methyltransferase TRM6-TRM61 from Saccharomyces cerevisiae. Sci Rep, 6, 2016
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5WZJ
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![BU of 5wzj by Molmil](/molmil-images/mine/5wzj) | Structure of APUM23-GGAUUUGACGG | 分子名称: | Pumilio homolog 23, RNA (5'-R(*GP*GP*AP*UP*UP*UP*GP*AP*CP*GP*G)-3') | 著者 | Bao, H, Wang, N, Wang, C, Jiang, Y, Wu, J, Shi, Y. | 登録日 | 2017-01-18 | 公開日 | 2017-09-27 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.101 Å) | 主引用文献 | Structural basis for the specific recognition of 18S rRNA by APUM23. Nucleic Acids Res., 45, 2017
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5WZK
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![BU of 5wzk by Molmil](/molmil-images/mine/5wzk) | Structure of APUM23-deletion-of-insert-region-GGAAUUGACGG | 分子名称: | Pumilio homolog 23, RNA (5'-R(*GP*GP*AP*AP*UP*UP*GP*AP*CP*GP*G)-3') | 著者 | Bao, H, Wang, N, Wang, C, Jiang, Y, Wu, J, Shi, Y. | 登録日 | 2017-01-18 | 公開日 | 2017-09-27 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural basis for the specific recognition of 18S rRNA by APUM23. Nucleic Acids Res., 45, 2017
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1QQW
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![BU of 1qqw by Molmil](/molmil-images/mine/1qqw) | CRYSTAL STRUCTURE OF HUMAN ERYTHROCYTE CATALASE | 分子名称: | CATALASE, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Ko, T.P, Safo, M.K, Musayev, F.N, Wang, C, Wu, S.H, Abraham, D.J. | 登録日 | 1999-06-09 | 公開日 | 1999-06-14 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Structure of human erythrocyte catalase. Acta Crystallogr.,Sect.D, 56, 2000
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3W1Y
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1XMJ
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![BU of 1xmj by Molmil](/molmil-images/mine/1xmj) | Crystal structure of human deltaF508 human NBD1 domain with ATP | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION | 著者 | Lewis, H.A, Zhao, X, Wang, C, Sauder, J.M, Rooney, I, Noland, B.W, Lorimer, D, Kearins, M.C, Conners, K, Condon, B, Maloney, P.C, Guggino, W.B, Hunt, J.F, Emtage, S, Structural GenomiX | 登録日 | 2004-10-02 | 公開日 | 2004-11-09 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Impact of the delta-F508 Mutation in First Nucleotide-binding Domain of Human Cystic Fibrosis Transmembrane Conductance Regulator on Domain Folding and Structure J.Biol.Chem., 280, 2005
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3WBX
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3WBY
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1XMI
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![BU of 1xmi by Molmil](/molmil-images/mine/1xmi) | Crystal structure of human F508A NBD1 domain with ATP | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION | 著者 | Lewis, H.A, Zhao, X, Wang, C, Sauder, J.M, Rooney, I, Noland, B.W, Lorimer, D, Kearins, M.C, Conners, K, Condon, B, Maloney, P.C, Guggino, W.B, Hunt, J.F, Emtage, S, Structural GenomiX | 登録日 | 2004-10-02 | 公開日 | 2004-11-09 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Impact of the delta-F508 Mutation in First Nucleotide-binding Domain of Human Cystic Fibrosis Transmembrane Conductance Regulator on Domain Folding and Structure J.Biol.Chem., 280, 2005
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3WBW
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![BU of 3wbw by Molmil](/molmil-images/mine/3wbw) | Crystal structure of Gox0644 in complex with NADPH | 分子名称: | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Putative 2,5-diketo-D-gluconic acid reductase, SULFATE ION | 著者 | Yuan, Y.A, Wang, C. | 登録日 | 2013-05-22 | 公開日 | 2014-05-28 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Crystal structure of Gox0644 in complex with NADPH To be Published
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7DHS
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![BU of 7dhs by Molmil](/molmil-images/mine/7dhs) | Crystal Structure Analysis of the BRD4 | 分子名称: | 6-(3,5-dimethyl-1,2-oxazol-4-yl)-1-[(1R)-1-phenylethyl]benzo[cd]indol-2-one, Bromodomain-containing protein 4 | 著者 | Wu, T, Xiang, Q, Wang, C, Wu, C, Zhang, C, Zhang, M, Liu, Z, Zhang, Y, Xiao, L, Xu, Y. | 登録日 | 2020-11-17 | 公開日 | 2021-09-15 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | 主引用文献 | Y06014 is a selective BET inhibitor for the treatment of prostate cancer. Acta Pharmacol.Sin., 42, 2021
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1Z2B
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![BU of 1z2b by Molmil](/molmil-images/mine/1z2b) | Tubulin-colchicine-vinblastine: stathmin-like domain complex | 分子名称: | (2ALPHA,2'BETA,3BETA,4ALPHA,5BETA)-VINCALEUKOBLASTINE, 2-MERCAPTO-N-[1,2,3,10-TETRAMETHOXY-9-OXO-5,6,7,9-TETRAHYDRO-BENZO[A]HEPTALEN-7-YL]ACETAMIDE, GUANOSINE-5'-DIPHOSPHATE, ... | 著者 | Gigant, B, Wang, C, Ravelli, R.B.G, Roussi, F, Steinmetz, M.O, Curmi, P.A, Sobel, A, Knossow, M. | 登録日 | 2005-03-08 | 公開日 | 2005-05-31 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (4.1 Å) | 主引用文献 | Structural basis for the regulation of tubulin by vinblastine. Nature, 435, 2005
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6KZJ
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![BU of 6kzj by Molmil](/molmil-images/mine/6kzj) | Crystal structure of Ankyrin B/NdeL1 complex | 分子名称: | Ankyrin-2, Nuclear distribution protein nudE-like 1 | 著者 | Ye, J, Li, J, Ye, F, Zhang, M, Zhang, Y, Wang, C. | 登録日 | 2019-09-24 | 公開日 | 2020-01-15 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Mechanistic insights into the interactions of dynein regulator Ndel1 with neuronal ankyrins and implications in polarity maintenance. Proc.Natl.Acad.Sci.USA, 117, 2020
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2LZ3
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6LOD
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![BU of 6lod by Molmil](/molmil-images/mine/6lod) | Cryo-EM structure of the air-oxidized photosynthetic alternative complex III from Roseiflexus castenholzii | 分子名称: | Cytochrome c domain-containing protein, FE3-S4 CLUSTER, Fe-S-cluster-containing hydrogenase components 1-like protein, ... | 著者 | Shi, Y, Xin, Y.Y, Wang, C, Blankenship, R.E, Sun, F, Xu, X.L. | 登録日 | 2020-01-05 | 公開日 | 2020-11-04 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Cryo-EM structures of the air-oxidized and dithionite-reduced photosynthetic alternative complex III from Roseiflexus castenholzii . Sci Adv, 6, 2020
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6LOE
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![BU of 6loe by Molmil](/molmil-images/mine/6loe) | Cryo-EM structure of the dithionite-reduced photosynthetic alternative complex III from Roseiflexus castenholzii | 分子名称: | Cytochrome c domain-containing protein, FE3-S4 CLUSTER, Fe-S-cluster-containing hydrogenase components 1-like protein, ... | 著者 | Shi, Y, Xin, Y.Y, Wang, C, Blankenship, R.E, Sun, F, Xu, X.L. | 登録日 | 2020-01-05 | 公開日 | 2020-11-04 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Cryo-EM structures of the air-oxidized and dithionite-reduced photosynthetic alternative complex III from Roseiflexus castenholzii . Sci Adv, 6, 2020
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2LZ4
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2VGG
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![BU of 2vgg by Molmil](/molmil-images/mine/2vgg) | HUMAN ERYTHROCYTE PYRUVATE KINASE: R479H MUTANT | 分子名称: | 1,6-di-O-phosphono-beta-D-fructofuranose, 2-PHOSPHOGLYCOLIC ACID, MANGANESE (II) ION, ... | 著者 | Valentini, G, Chiarelli, L.R, Fortin, R, Dolzan, M, Galizzi, A, Abraham, D.J, Wang, C, Bianchi, P, Zanella, A, Mattevi, A. | 登録日 | 2007-11-13 | 公開日 | 2007-11-20 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.74 Å) | 主引用文献 | Structure and Function of Human Erythrocyte Pyruvate Kinase. Molecular Basis of Nonspherocytic Hemolytic Anemia. J.Biol.Chem., 277, 2002
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