5HZV
 
 | | Crystal structure of the zona pellucida module of human endoglin/CD105 | | 分子名称: | GLYCEROL, Maltose-binding periplasmic protein,Endoglin, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | | 著者 | Bokhove, M, Saito, T, Jovine, L. | | 登録日 | 2016-02-03 | | 公開日 | 2017-06-07 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural Basis of the Human Endoglin-BMP9 Interaction: Insights into BMP Signaling and HHT1.
Cell Rep, 19, 2017
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4MZ9
 | | Revised structure of E. coli SSB | | 分子名称: | Single-stranded DNA-binding protein | | 著者 | Oakley, A.J. | | 登録日 | 2013-09-29 | | 公開日 | 2013-12-18 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Intramolecular binding mode of the C-terminus of Escherichia coli single-stranded DNA binding protein determined by nuclear magnetic resonance spectroscopy.
Nucleic Acids Res., 42, 2014
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6LKD
 | | in meso full-length rat KMO in complex with a pyrazoyl benzoic acid inhibitor | | 分子名称: | 5-[5-(4-chloranyl-3-fluoranyl-phenyl)-4-methyl-pyrazol-1-yl]-2-phenylmethoxy-benzoic acid, CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, ... | | 著者 | Mimasu, S, Yamagishi, H, Kiyohara, M, Kakefuda, K, Okuda, T. | | 登録日 | 2019-12-19 | | 公開日 | 2020-12-23 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Full-length in meso structure and mechanism of rat kynurenine 3-monooxygenase inhibition.
Commun Biol, 4, 2021
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6LKE
 | | in meso full-length rat KMO in complex with an inhibitor identified via DNA-encoded chemical library screening | | 分子名称: | 4-chloranyl-2-[[5-chloranyl-2-(5-methoxy-1,3-dihydroisoindol-2-yl)-1,3-thiazol-4-yl]carbonyl-methyl-amino]-5-fluoranyl-benzoic acid, CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, ... | | 著者 | Mimasu, S, Yamagishi, H, Kiyohara, M, Hupp, D.C, Liu, J, Kakefuda, K, Okuda, T. | | 登録日 | 2019-12-19 | | 公開日 | 2020-12-23 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Full-length in meso structure and mechanism of rat kynurenine 3-monooxygenase inhibition.
Commun Biol, 4, 2021
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8J6N
 | | Crystal structure of Cystathionine gamma-lyase in complex with compound 1 | | 分子名称: | 1,2-ETHANEDIOL, Cystathionine gamma-lyase, GLYCEROL, ... | | 著者 | Hibi, R, Toma-Fukai, S, Shimizu, T, Hanaoka, K. | | 登録日 | 2023-04-26 | | 公開日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Discovery of a cystathionine gamma-lyase (CSE) selective inhibitor targeting active-site pyridoxal 5'-phosphate (PLP) via Schiff base formation.
Sci Rep, 13, 2023
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6TJX
 | | Cryo-EM structure of TypeII tau filaments extracted from the brains of individuals with Corticobasal degeneration | | 分子名称: | Microtubule-associated protein tau | | 著者 | Zhang, W, Murzin, A.G, Falcon, B, Shi, Y, Goedert, M, Scheres, S.H.W. | | 登録日 | 2019-11-27 | | 公開日 | 2020-02-05 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Novel tau filament fold in corticobasal degeneration.
Nature, 580, 2020
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6TJO
 | | Cryo-EM structure of TypeI tau filaments extracted from the brains of individuals with Corticobasal degeneration | | 分子名称: | Microtubule-associated protein tau | | 著者 | Zhang, W, Murzin, A.G, Falcon, B, Shi, Y, Goedert, M, Scheres, S.H.W. | | 登録日 | 2019-11-26 | | 公開日 | 2020-02-05 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Novel tau filament fold in corticobasal degeneration.
Nature, 580, 2020
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2RR2
 | | Structure of O-fucosylated epidermal growth factor-like repeat 12 of mouse Notch-1 receptor | | 分子名称: | Neurogenic locus notch homolog protein 1, alpha-L-fucopyranose | | 著者 | Hosoguchi, K, Shimizu, K, Fujitani, N, Nishimura, S. | | 登録日 | 2010-02-26 | | 公開日 | 2010-10-13 | | 最終更新日 | 2020-07-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Chemical Synthesis, Folding, and Structural Insights into O-Fucosylated Epidermal Growth Factor-like Repeat 12 of Mouse Notch-1 Receptor
J.Am.Chem.Soc., 132, 2010
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2RR0
 | | Structure of epidermal growth factor-like repeat 12 of mouse Notch-1 receptor | | 分子名称: | Neurogenic locus notch homolog protein 1 | | 著者 | Hosoguchi, K, Shimizu, K, Fujitani, N, Nishimura, S. | | 登録日 | 2010-02-26 | | 公開日 | 2010-10-13 | | 最終更新日 | 2011-07-13 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Chemical Synthesis, Folding, and Structural Insights into O-Fucosylated Epidermal Growth Factor-like Repeat 12 of Mouse Notch-1 Receptor
J.Am.Chem.Soc., 132, 2010
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2RQZ
 | | Structure of sugar modified epidermal growth factor-like repeat 12 of mouse Notch-1 receptor | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-alpha-L-fucopyranose, Neurogenic locus notch homolog protein 1 | | 著者 | Shimizu, K, Fujitani, N, Hosoguchi, K, Nishimura, S. | | 登録日 | 2010-02-26 | | 公開日 | 2010-10-13 | | 最終更新日 | 2020-07-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Chemical Synthesis, Folding, and Structural Insights into O-Fucosylated Epidermal Growth Factor-like Repeat 12 of Mouse Notch-1 Receptor
J.Am.Chem.Soc., 132, 2010
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4YRW
 | | rat xanthine oxidoreductase, C-terminal deletion protein variant | | 分子名称: | BICARBONATE ION, CALCIUM ION, FE2/S2 (INORGANIC) CLUSTER, ... | | 著者 | Okamoto, K. | | 登録日 | 2015-03-16 | | 公開日 | 2015-04-29 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | The C-terminal peptide plays a role in the formation of an intermediate form during the transition between xanthine dehydrogenase and xanthine oxidase
Febs J., 282, 2015
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5JYM
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1O16
 | | RECOMBINANT SPERM WHALE MYOGLOBIN H64D/V68S/D122N MUTANT (MET) | | 分子名称: | MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION | | 著者 | Phillips Jr, G.N. | | 登録日 | 2002-10-25 | | 公開日 | 2003-11-04 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Molecular engineering of myoglobin: influence of residue 68 on the rate and the
enantioselectivity of oxidation reactions catalyzed by H64D/V68X myoglobin
Biochemistry, 42, 2003
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7C7F
 | | Crystal structures of AKR1C3 binary complex with NADP+ | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, Aldo-keto reductase family 1 member C3, ... | | 著者 | Irie, K, Toyooka, N, Endo, S. | | 登録日 | 2020-05-25 | | 公開日 | 2020-09-23 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Development of Novel AKR1C3 Inhibitors as New Potential Treatment for Castration-Resistant Prostate Cancer.
J.Med.Chem., 63, 2020
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5ZRU
 | | Crystal structure of Agl-KA catalytic domain | | 分子名称: | 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, Alpha-1,3-glucanase, CALCIUM ION, ... | | 著者 | Yano, S, Makabe, K. | | 登録日 | 2018-04-25 | | 公開日 | 2019-10-23 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.833 Å) | | 主引用文献 | Crystal structure of the catalytic unit of GH 87-type alpha-1,3-glucanase Agl-KA from Bacillus circulans.
Sci Rep, 9, 2019
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7C7G
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1UAI
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3NF5
 | | Crystal structure of the C-terminal domain of nuclear pore complex component NUP116 from Candida glabrata | | 分子名称: | GLYCEROL, Nucleoporin NUP116 | | 著者 | Sampathkumar, P, Manglicmot, D, Bain, K, Gilmore, J, Gheyi, T, Rout, M, Sali, A, Atwell, S, Thompson, D.A, Emtage, J.S, Wasserman, S, Sauder, J.M, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2010-06-09 | | 公開日 | 2010-08-04 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | Atomic structure of the nuclear pore complex targeting domain of a Nup116 homologue from the yeast, Candida glabrata.
Proteins, 80, 2012
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7C7H
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7F9F
 | | Thrombocorticin | | 分子名称: | MAGNESIUM ION, Thrombocorticin | | 著者 | Kageyama, H, Onodera, K, Sakai, R, Tanaka, Y, Freymann, D.M. | | 登録日 | 2021-07-04 | | 公開日 | 2022-07-06 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.411 Å) | | 主引用文献 | A marine sponge-derived lectin reveals hidden pathway for thrombopoietin receptor activation.
Nat Commun, 13, 2022
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7F9G
 | | Thrombocorticin in complex with Ca2+ and fucose | | 分子名称: | CALCIUM ION, Thrombocorticin, alpha-L-fucopyranose | | 著者 | Kageyama, H, Onodera, K, Sakai, R, Tanaka, Y. | | 登録日 | 2021-07-04 | | 公開日 | 2022-07-06 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.331 Å) | | 主引用文献 | A marine sponge-derived lectin reveals hidden pathway for thrombopoietin receptor activation.
Nat Commun, 13, 2022
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7F9J
 | | Thrombocorticin Q25K in complex with Ca2+ | | 分子名称: | CALCIUM ION, Thrombocorticin Q25K mutant | | 著者 | Kageyama, H, Onodera, K, Sakai, R, Tanaka, Y. | | 登録日 | 2021-07-04 | | 公開日 | 2022-07-06 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | A marine sponge-derived lectin reveals hidden pathway for thrombopoietin receptor activation.
Nat Commun, 13, 2022
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7F91
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7FBL
 | | Thrombocorticin in complex with Ca2+ and mannose | | 分子名称: | CALCIUM ION, Thrombocorticin, alpha-D-mannopyranose | | 著者 | Kageyama, H, Onodera, K, Sakai, R, Tanaka, Y. | | 登録日 | 2021-07-11 | | 公開日 | 2022-07-13 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.419 Å) | | 主引用文献 | A marine sponge-derived lectin reveals hidden pathway for thrombopoietin receptor activation.
Nat Commun, 13, 2022
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2RGH
 | | Structure of Alpha-Glycerophosphate Oxidase from Streptococcus sp.: A Template for the Mitochondrial Alpha-Glycerophosphate Dehydrogenase | | 分子名称: | Alpha-Glycerophosphate Oxidase, FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION | | 著者 | Colussi, T, Boles, W, Mallett, T.C, Karplus, P.A, Claiborne, A. | | 登録日 | 2007-10-01 | | 公開日 | 2008-01-15 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure of alpha-glycerophosphate oxidase from Streptococcus sp.: a template for the mitochondrial alpha-glycerophosphate dehydrogenase.
Biochemistry, 47, 2008
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