3V19
 
 | | Forestalling insulin fibrillation by insertion of a chiral clamp mechanism-based application of protein engineering to global health | | 分子名称: | CHLORIDE ION, Insulin, PHENOL, ... | | 著者 | Wan, Z.L, Hua, Q.X, Wickramasinghe, N.P, Huang, K, Petkova, A.T, Hu, S.Q, Phillips, N.B, Yeh, I.J, Whittake, J, Ismail-Beigi, F, Katsoyyannis, P.G, Tycko, R, Weiss, M.A. | | 登録日 | 2011-12-09 | | 公開日 | 2012-12-12 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Forestalling insulin fibrillation by insertion of a
chiral clamp mechanism-based application of protein engineering to global health
To be Published
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3V1G
 | | Forestalling insulin fibrillation by insertion of a chiral clamp mechanism-based application of protein engineering to global health | | 分子名称: | CHLORIDE ION, Insulin, PHENOL, ... | | 著者 | Wan, Z.L, Hua, Q.X, Wickramasinghe, N.P, Huang, K, Petkova, A.T, Hu, S.Q, Phillips, N.B, Yeh, I.J, Whittake, J, Ismail-Beigi, F, Katsoyyannis, P.G, Tycko, R, Weiss, M.A. | | 登録日 | 2011-12-09 | | 公開日 | 2012-12-12 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Forestalling insulin fibrillation by insertion of a
chiral clamp mechanism-based application of protein engineering to global health
To be Published
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3BXD
 | | Crystal structure of Mouse Myo-inositol oxygenase (re-refined) | | 分子名称: | 1,2,3,4,5,6-HEXAHYDROXY-CYCLOHEXANE, FE (III) ION, FORMIC ACID, ... | | 著者 | Hallberg, B.M. | | 登録日 | 2008-01-13 | | 公開日 | 2008-02-05 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural and biophysical characterization of human myo-inositol oxygenase.
J.Biol.Chem., 283, 2008
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3BXQ
 | | The structure of a mutant insulin uncouples receptor binding from protein allostery. An electrostatic block to the TR transition | | 分子名称: | ZINC ION, insulin A chain, insulin B chain | | 著者 | Wan, Z.L, Huang, K, Hu, S.Q, Whittaker, J, Weiss, M.A. | | 登録日 | 2008-01-14 | | 公開日 | 2008-05-20 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | The structure of a mutant insulin uncouples receptor binding from protein allostery. An electrostatic block to the TR transition.
J.Biol.Chem., 283, 2008
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1URI
 | | AZURIN MUTANT WITH MET 121 REPLACED BY GLN | | 分子名称: | AZURIN, COPPER (II) ION, SULFATE ION | | 著者 | Romero, A, Nar, H, Huber, R, Messerschmidt, A. | | 登録日 | 1996-11-14 | | 公開日 | 1997-04-01 | | 最終更新日 | 2018-04-18 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | X-ray analysis and spectroscopic characterization of M121Q azurin. A copper site model for stellacyanin.
J.Mol.Biol., 229, 1993
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1OS4
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1ZNI
 | | INSULIN | | 分子名称: | CHLORIDE ION, INSULIN, ZINC ION | | 著者 | Turkenburg, M.G.W, Whittingham, J.L, Dodson, G.G, Dodson, E.J, Xiao, B, Bentley, G.A. | | 登録日 | 1997-09-23 | | 公開日 | 1998-01-28 | | 最終更新日 | 2018-07-04 | | 実験手法 | X-RAY DIFFRACTION (1.498 Å) | | 主引用文献 | Structure of insulin in 4-zinc insulin.
Nature, 261, 1976
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1OVB
 | | THE MECHANISM OF IRON UPTAKE BY TRANSFERRINS: THE STRUCTURE OF AN 18KD NII-DOMAIN FRAGMENT AT 2.3 ANGSTROMS RESOLUTION | | 分子名称: | CARBONATE ION, FE (III) ION, OVOTRANSFERRIN | | 著者 | Kuser, P, Lindley, P, Sarra, R. | | 登録日 | 1992-10-05 | | 公開日 | 1994-01-31 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | The mechanism of iron uptake by transferrins: the structure of an 18 kDa NII-domain fragment from duck ovotransferrin at 2.3 A resolution.
Acta Crystallogr.,Sect.D, 49, 1993
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1OS3
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3FQ9
 | | Design of an insulin analog with enhanced receptor-binding selectivity. Rationale, structure, and therapeutic implications | | 分子名称: | Insulin, ZINC ION | | 著者 | Zhao, M, Wan, Z.L, Whittaker, L, Xu, B, Phillips, N, Katsoyannis, P, Whittaker, J, Weiss, M.A. | | 登録日 | 2009-01-07 | | 公開日 | 2009-08-04 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | Design of an insulin analog with enhanced receptor binding selectivity: rationale, structure, and therapeutic implications.
J.Biol.Chem., 284, 2009
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1DOT
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2A3G
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1BEN
 | | INSULIN COMPLEXED WITH 4-HYDROXYBENZAMIDE | | 分子名称: | 4-HYDROXYBENZAMIDE, CHLORIDE ION, HUMAN INSULIN, ... | | 著者 | Smith, G.D, Ciszak, E, Pangborn, W. | | 登録日 | 1996-02-15 | | 公開日 | 1996-07-11 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | A novel complex of a phenolic derivative with insulin: structural features related to the T-->R transition.
Protein Sci., 5, 1996
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3ROV
 | | Insulin's biosynthesis and activity have opposing structural requirements: a new factor in neonatal diabetes mellitus | | 分子名称: | CHLORIDE ION, Insulin, PHENOL, ... | | 著者 | Weiss, M.A, Wan, Z.L, Dodson, E.J, Liu, M, Xu, B, Hua, Q.X, Turkenburg, M, Whittingham, J, Nakagawa, S.H, Huang, K, Hu, S.Q, Jia, W.H, Wang, S.H, Brange, J, Whittaker, J, Arvan, P, Katsoyannis, P.G, Dodson, G.G. | | 登録日 | 2011-04-26 | | 公開日 | 2012-05-02 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Insulin's biosynthesis and activity have opposing structural requirements: a new factor in neonatal diabetes mellitus
To be Published
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3GKY
 | | The Structural Basis of an ER Stress-Associated Bottleneck in a Protein Folding Landscape | | 分子名称: | CHLORIDE ION, Insulin A chain, Insulin B chain, ... | | 著者 | Liu, M, Wan, Z.L, Chu, Y.C, Alddin, H, Klaproth, B, Weiss, M.A. | | 登録日 | 2009-03-11 | | 公開日 | 2009-03-24 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structure of a "nonfoldable" insulin: IMPAIRED FOLDING EFFICIENCY DESPITE NATIVE ACTIVITY.
J.Biol.Chem., 284, 2009
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3JSD
 | | Insulin's biosynthesis and activity have opposing structural requirements: a new factor in neonatal diabetes mellitus | | 分子名称: | CHLORIDE ION, Insulin A chain, Insulin B chain, ... | | 著者 | Weiss, M.A, Wan, Z.L, Dodson, E.J, Liu, M, Xu, B, Hua, Q.X, Turkenburg, M, Whittingham, J, Nakagawa, S.H, Huang, K, Hu, S.Q, Jia, W.H, Wang, S.H, Brange, J, Whittaker, J, Arvan, P, Katsoyannis, P.G, Dodson, G.G. | | 登録日 | 2009-09-10 | | 公開日 | 2010-09-15 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Insulin's biosynthesis and activity have opposing structural requirements: a new factor in neonatal diabetes mellitus
To be Published
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1IZA
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1IZB
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1JVB
 | | ALCOHOL DEHYDROGENASE FROM THE ARCHAEON SULFOLOBUS SOLFATARICUS | | 分子名称: | NAD(H)-DEPENDENT ALCOHOL DEHYDROGENASE, ZINC ION | | 著者 | Esposito, L, Sica, F, Zagari, A, Mazzarella, L. | | 登録日 | 2001-08-29 | | 公開日 | 2002-08-29 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Crystal structure of the alcohol dehydrogenase from the hyperthermophilic archaeon Sulfolobus solfataricus at 1.85 A resolution.
J.Mol.Biol., 318, 2002
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1CE2
 | | STRUCTURE OF DIFERRIC BUFFALO LACTOFERRIN AT 2.5A RESOLUTION | | 分子名称: | CARBONATE ION, FE (III) ION, PROTEIN (LACTOFERRIN) | | 著者 | Karthikeyan, S, Paramasivam, M, Yadav, S, Srinivasan, A, Singh, T.P. | | 登録日 | 1999-03-13 | | 公開日 | 1999-03-19 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure of buffalo lactoferrin at 2.5 A resolution using crystals grown at 303 K shows different orientations of the N and C lobes.
Acta Crystallogr.,Sect.D, 55, 1999
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1BIY
 | | STRUCTURE OF DIFERRIC BUFFALO LACTOFERRIN | | 分子名称: | CARBONATE ION, FE (III) ION, LACTOFERRIN | | 著者 | Karthikeyan, S, Yadav, S, Singh, T.P. | | 登録日 | 1998-06-21 | | 公開日 | 1999-01-13 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (3.37 Å) | | 主引用文献 | Structure of buffalo lactoferrin at 3.3 A resolution at 277 K.
Acta Crystallogr.,Sect.D, 56, 2000
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1E84
 | | Cytochrome c' from Alcaligenes xylosoxidans - reduced structure | | 分子名称: | CYTOCHROME C', HEME C | | 著者 | Lawson, D.M, Stevenson, C.E.M, Andrew, C.R, Eady, R.R. | | 登録日 | 2000-09-15 | | 公開日 | 2000-11-06 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Unprecedented Proximal Binding of Nitric Oxide to Heme: Implications for Guanylate Cyclase
Embo J., 19, 2000
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1E86
 | | Cytochrome c' from Alcaligenes xylosoxidans - reduced structure with CO bound to distal side of heme | | 分子名称: | CARBON MONOXIDE, CYTOCHROME C', HEME C | | 著者 | Lawson, D.M, Stevenson, C.E.M, Andrew, C.R, Eady, R.R. | | 登録日 | 2000-09-15 | | 公開日 | 2000-11-06 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Unprecedented Proximal Binding of Nitric Oxide to Heme: Implications for Guanylate Cyclase
Embo J., 19, 2000
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1E83
 | | Cytochrome c' from Alcaligenes xylosoxidans - oxidized structure | | 分子名称: | CYTOCHROME C', HEME C | | 著者 | Lawson, D.M, Stevenson, C.E.M, Andrew, C.R, Eady, R.R. | | 登録日 | 2000-09-15 | | 公開日 | 2000-11-06 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Unprecedented Proximal Binding of Nitric Oxide to Heme: Implications for Guanylate Cyclase
Embo J., 19, 2000
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1E85
 | | Cytochrome c' from Alcaligenes xylosoxidans - reduced structure with NO bound to proximal side of heme | | 分子名称: | CYTOCHROME C', HEME C, NITRIC OXIDE | | 著者 | Lawson, D.M, Stevenson, C.E.M, Andrew, C.R, Eady, R.R. | | 登録日 | 2000-09-15 | | 公開日 | 2000-11-06 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | Unprecedented Proximal Binding of Nitric Oxide to Heme: Implications for Guanylate Cyclase.
Embo J., 19, 2000
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