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7Y5N
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BU of 7y5n by Molmil
Structure of 1:1 PAPP-A.ProMBP complex(half map)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Bone marrow proteoglycan, ...
著者Zhong, Q.H, Chu, H.L, Wang, G.P, Zhang, C, Wei, Y, Qiao, J, Hang, J.
登録日2022-06-17
公開日2023-01-11
実験手法ELECTRON MICROSCOPY (3.45 Å)
主引用文献Structural insights into the covalent regulation of PAPP-A activity by proMBP and STC2.
Cell Discov, 8, 2022
7Y5Q
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BU of 7y5q by Molmil
Structure of 1:1 PAPP-A.STC2 complex(half map)
分子名称: Maltose/maltodextrin-binding periplasmic protein,Pappalysin-1, Stanniocalcin-2, ZINC ION
著者Zhong, Q.H, Chu, H.L, Wang, G.P, Zhang, C, Wei, Y, Qiao, J, Hang, J.
登録日2022-06-17
公開日2023-01-11
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structural insights into the covalent regulation of PAPP-A activity by proMBP and STC2.
Cell Discov, 8, 2022
7JVB
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BU of 7jvb by Molmil
Crystal structure of the SARS-CoV-2 spike receptor-binding domain (RBD) with nanobody Nb20
分子名称: CACODYLATE ION, Nanobody Nb20, Spike protein S1
著者Xiang, Y, Xiao, Z, Liu, H, Sang, Z, Schneidman-Duhovny, D, Zhang, C, Shi, Y.
登録日2020-08-20
公開日2020-12-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.287 Å)
主引用文献Versatile and multivalent nanobodies efficiently neutralize SARS-CoV-2.
Science, 370, 2020
7KH0
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BU of 7kh0 by Molmil
Cryo-EM structure of the human arginine vasopressin AVP-vasopressin receptor V2R-Gs signaling complex
分子名称: Arg-vasopressin, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Wang, L, Xu, J, Gao, S, Sun, D, Liu, H, Liu, Z, Du, Y, Zhang, C.
登録日2020-10-19
公開日2021-05-26
最終更新日2023-03-29
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Cryo-EM structure of the AVP-vasopressin receptor 2-G s signaling complex.
Cell Res., 31, 2021
1XM5
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BU of 1xm5 by Molmil
Crystal structure of metal-dependent hydrolase ybeY from E. coli, Pfam UPF0054
分子名称: Hypothetical UPF0054 protein ybeY, NICKEL (II) ION
著者Fedorov, A.A, Fedorov, E.V, Shi, W, Ramagopal, U.A, Thirumuruhan, R, Almo, S.C, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2004-10-01
公開日2004-10-12
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The ybeY protein from Escherichia coli is a metalloprotein.
Acta Crystallogr.,Sect.F, 61, 2005
3TPX
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BU of 3tpx by Molmil
Crystal structure of human MDM2 in complex with a trifluoromethylated D-peptide inhibitor
分子名称: ACETATE ION, CHLORIDE ION, D-peptide inhibitor DPMI-delta, ...
著者Wu, X, Pazgier, M.
登録日2011-09-08
公開日2012-06-20
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献An Ultrahigh Affinity d-Peptide Antagonist Of MDM2.
J.Med.Chem., 55, 2012
3D0R
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BU of 3d0r by Molmil
Crystal structure of calG3 from Micromonospora echinospora determined in space group P2(1)
分子名称: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Protein CalG3
著者Bitto, E, Bingman, C.A, Wesenberg, G.E, Phillips Jr, G.N.
登録日2008-05-02
公開日2008-06-24
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Biochemical and structural insights of the early glycosylation steps in calicheamicin biosynthesis.
Chem.Biol., 15, 2008
3D0Q
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BU of 3d0q by Molmil
Crystal structure of calG3 from Micromonospora echinospora determined in space group I222
分子名称: 3[N-MORPHOLINO]PROPANE SULFONIC ACID, Protein CalG3
著者Bitto, E, Singh, S, Bingman, C.A, Wesenberg, G.E, Phillips Jr, G.N.
登録日2008-05-02
公開日2008-06-24
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.79 Å)
主引用文献Biochemical and structural insights of the early glycosylation steps in calicheamicin biosynthesis.
Chem.Biol., 15, 2008
6KIK
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BU of 6kik by Molmil
Crystal structure of a thermostable aldo-keto reductase Tm1743 in complex with inhibitor tolrestat
分子名称: Oxidoreductase, aldo/keto reductase family, TOLRESTAT
著者Zhang, C.Y, Liu, X.M, Wang, C, Tang, W.R.
登録日2019-07-18
公開日2019-09-25
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.601 Å)
主引用文献Tolrestat acts atypically as a competitive inhibitor of the thermostable aldo-keto reductase Tm1743 from Thermotoga maritima.
Febs Lett., 594, 2020
6KIY
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BU of 6kiy by Molmil
Crystal structure of a thermostable aldo-keto reductase Tm1743 in complex with inhibitor Epalrestat
分子名称: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Oxidoreductase, aldo/keto reductase family, ...
著者Zhang, C.Y, Liu, X.M, Wang, C, Min, Z.Z, Xu, X.L.
登録日2019-07-20
公開日2019-09-25
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Tolrestat acts atypically as a competitive inhibitor of the thermostable aldo-keto reductase Tm1743 from Thermotoga maritima.
Febs Lett., 594, 2020
6KY6
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BU of 6ky6 by Molmil
Crystal structure of a thermostable aldo-keto reductase Tm1743 in complexs with inhibitor epalrestat in space group P3221cc
分子名称: 2,5-diketo-D-gluconic acid reductase, CHLORIDE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Zhang, C.Y, Min, Z.Z, Liu, X.M, Wang, C, Tang, W.R.
登録日2019-09-16
公開日2019-10-02
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Tolrestat acts atypically as a competitive inhibitor of the thermostable aldo-keto reductase Tm1743 from Thermotoga maritima.
Febs Lett., 594, 2020
7DCX
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BU of 7dcx by Molmil
S-3C1-F3a structure, two RBDs are up and one RBD is down, each RBD binds with a 3C1 fab.
分子名称: Spike glycoprotein, The heavy chain of 3C1 fab that binds with the up RBD, The light chain of 3C1 fab
著者Cong, Y, Liu, C.X.
登録日2020-10-27
公開日2020-12-02
最終更新日2021-03-10
実験手法ELECTRON MICROSCOPY (5.9 Å)
主引用文献Development and structural basis of a two-MAb cocktail for treating SARS-CoV-2 infections.
Nat Commun, 12, 2021
7DK6
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BU of 7dk6 by Molmil
S-2H2-F2 structure, two RBDs are up and one RBD is down, each up RBD binds with a 2H2 Fab.
分子名称: Spike glycoprotein, The heavy chain of 2H2 Fab, The light chain of 2H2 Fab
著者Cong, Y, Wang, Y.F.
登録日2020-11-23
公開日2020-12-02
最終更新日2021-03-10
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Development and structural basis of a two-MAb cocktail for treating SARS-CoV-2 infections.
Nat Commun, 12, 2021
7DD8
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BU of 7dd8 by Molmil
S-3C1-F1 structure, one RBD is up and two RBDs are down, the up RBD binds with a 3C1 fab
分子名称: Spike glycoprotein, The heavy chain of 3C1 fab, The light chain of 3C1 chain
著者Cong, Y, Liu, C.X.
登録日2020-10-28
公開日2020-12-02
最終更新日2021-01-27
実験手法ELECTRON MICROSCOPY (7.5 Å)
主引用文献Development and structural basis of a two-MAb cocktail for treating SARS-CoV-2 infections.
Nat Commun, 12, 2021
7DCC
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BU of 7dcc by Molmil
S-3C1-F3b structure, all the three RBDs are in the up conformation and each of them associates with a 3C1 Fab
分子名称: Spike glycoprotein, The heavy chain of 3C1 fab, The light chain of 3C1 fab
著者Cong, Y, Liu, C.X.
登録日2020-10-24
公開日2020-12-02
最終更新日2021-03-10
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Development and structural basis of a two-MAb cocktail for treating SARS-CoV-2 infections.
Nat Commun, 12, 2021
7DK5
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BU of 7dk5 by Molmil
S-2H2-F1 structure, one RBD is up and two RBDs are down, only up RBD binds with a 2H2 Fab
分子名称: Spike glycoprotein, The heavy chain of 2H2 Fab, The light chain of 2H2 Fab
著者Cong, Y, Wang, Y.F.
登録日2020-11-23
公開日2020-12-02
最終更新日2021-03-10
実験手法ELECTRON MICROSCOPY (13.5 Å)
主引用文献Development and structural basis of a two-MAb cocktail for treating SARS-CoV-2 infections.
Nat Commun, 12, 2021
7DDN
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BU of 7ddn by Molmil
SARS-Cov2 S protein at open state
分子名称: Spike glycoprotein
著者Cong, Y, Liu, C.X.
登録日2020-10-29
公開日2020-11-25
最終更新日2021-01-27
実験手法ELECTRON MICROSCOPY (6.3 Å)
主引用文献Development and structural basis of a two-MAb cocktail for treating SARS-CoV-2 infections.
Nat Commun, 12, 2021
7DD2
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BU of 7dd2 by Molmil
S-3C1-F2 structure, two RBDs are up and one RBD is down, the two up RBD bind with a 3C1 fab.
分子名称: Spike glycoprotein, The heavy chain of 3C1 fab, The light chain of 3C1 fab
著者Cong, Y, Liu, C.X.
登録日2020-10-27
公開日2020-12-02
最終更新日2021-03-10
実験手法ELECTRON MICROSCOPY (5.6 Å)
主引用文献Development and structural basis of a two-MAb cocktail for treating SARS-CoV-2 infections.
Nat Commun, 12, 2021
7DK4
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BU of 7dk4 by Molmil
S-2H2-F3a structure, two RBDs are up and one RBD is down, each RBD binds with a 2H2 Fab.
分子名称: Spike glycoprotein, The heavy chain of 2H2 Fab, The light chain of 2H2 Fab
著者Cong, Y, Wang, Y.F.
登録日2020-11-23
公開日2020-12-02
最終更新日2021-03-10
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Development and structural basis of a two-MAb cocktail for treating SARS-CoV-2 infections.
Nat Commun, 12, 2021
7DDD
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BU of 7ddd by Molmil
SARS-Cov2 S protein at close state
分子名称: Spike glycoprotein
著者Cong, Y, Liu, C.X.
登録日2020-10-28
公開日2020-11-25
最終更新日2021-01-27
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Development and structural basis of a two-MAb cocktail for treating SARS-CoV-2 infections.
Nat Commun, 12, 2021
7DK7
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BU of 7dk7 by Molmil
S-2H2-F3b structure, three RBDs are up and each RBD binds with a 2H2 Fab.
分子名称: Spike glycoprotein, The heavy chain fragment of 2H2 Fab, The light chain fragment of 2H2 Fab
著者Cong, Y, Wang, Y.F.
登録日2020-11-23
公開日2020-12-02
最終更新日2021-03-10
実験手法ELECTRON MICROSCOPY (9.7 Å)
主引用文献Development and structural basis of a two-MAb cocktail for treating SARS-CoV-2 infections.
Nat Commun, 12, 2021
7ECY
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BU of 7ecy by Molmil
EV-D68 in complex with 2H12 Fab (State 3)
分子名称: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
著者Xu, C, Cong, Y.
登録日2021-03-13
公開日2021-03-31
最終更新日2021-06-02
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Functional and structural characterization of a two-MAb cocktail for delayed treatment of enterovirus D68 infections.
Nat Commun, 12, 2021
7EBZ
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BU of 7ebz by Molmil
EV-D68 in complex with 2H12 Fab (state S1)
分子名称: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
著者Xu, C, Cong, Y.
登録日2021-03-11
公開日2021-03-31
最終更新日2021-06-02
実験手法ELECTRON MICROSCOPY (3.09 Å)
主引用文献Functional and structural characterization of a two-MAb cocktail for delayed treatment of enterovirus D68 infections.
Nat Commun, 12, 2021
7EBR
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BU of 7ebr by Molmil
EV-D68 in complex with 2H12 Fab (state S2)
分子名称: 2H12 Fab heavy chain, 2H12 Fab light chain, Capsid protein VP1, ...
著者Xu, C, Cong, Y.
登録日2021-03-10
公開日2021-03-31
最終更新日2021-06-02
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Functional and structural characterization of a two-MAb cocktail for delayed treatment of enterovirus D68 infections.
Nat Commun, 12, 2021
7EC5
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BU of 7ec5 by Molmil
EV-D68 in complex with 8F12 Fab
分子名称: 8F12 Fab heavy chain, 8F12 Fab light chain, Capsid protein VP1, ...
著者Xu, C, Cong, Y.
登録日2021-03-11
公開日2021-03-31
最終更新日2021-06-02
実験手法ELECTRON MICROSCOPY (2.89 Å)
主引用文献Functional and structural characterization of a two-MAb cocktail for delayed treatment of enterovirus D68 infections.
Nat Commun, 12, 2021

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