1KW1
| Crystal Structure of 3-Keto-L-Gulonate 6-Phosphate Decarboxylase with bound L-gulonate 6-phosphate | 分子名称: | 3-Keto-L-Gulonate 6-Phosphate Decarboxylase, L-GULURONIC ACID 6-PHOSPHATE, MAGNESIUM ION | 著者 | Wise, E, Yew, W.S, Babbitt, P.C, Gerlt, J.A, Rayment, I. | 登録日 | 2002-01-28 | 公開日 | 2002-04-15 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Homologous (beta/alpha)8-barrel enzymes that catalyze unrelated reactions: orotidine 5'-monophosphate decarboxylase and 3-keto-L-gulonate 6-phosphate decarboxylase. Biochemistry, 41, 2002
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1JD0
| CRYSTAL STRUCTURE OF THE EXTRACELLULAR DOMAIN OF HUMAN CARBONIC ANHYDRASE XII COMPLEXED WITH ACETAZOLAMIDE | 分子名称: | 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE, CARBONIC ANHYDRASE XII, ZINC ION | 著者 | Whittington, D.A, Waheed, A, Ulmasov, B, Shah, G.N, Grubb, J.H, Sly, W.S, Christianson, D.W. | 登録日 | 2001-06-11 | 公開日 | 2001-08-17 | 最終更新日 | 2011-11-16 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Crystal structure of the dimeric extracellular domain of human carbonic anhydrase XII, a bitopic membrane protein overexpressed in certain cancer tumor cells. Proc.Natl.Acad.Sci.USA, 98, 2001
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1KAQ
| Structure of Bacillus subtilis Nicotinic Acid Mononucleotide Adenylyl Transferase | 分子名称: | NICOTINATE-NUCLEOTIDE ADENYLYLTRANSFERASE, NICOTINIC ACID ADENINE DINUCLEOTIDE | 著者 | Olland, A.M, Underwood, K.W, Czerwinski, R.M, Lo, M.C, Aulabaugh, A, Bard, J, Stahl, M.L, Somers, W.S, Sullivan, F.X, Chopra, R. | 登録日 | 2001-11-02 | 公開日 | 2002-07-12 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Identification, characterization, and crystal structure of Bacillus subtilis nicotinic acid mononucleotide adenylyltransferase. J.Biol.Chem., 277, 2002
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1L0B
| Crystal Structure of rat Brca1 tandem-BRCT region | 分子名称: | BRCA1 | 著者 | Joo, W.S, Jeffrey, P.D, Cantor, S.B, Finnin, M.S, Livingston, D.M, Pavletich, N.P. | 登録日 | 2002-02-08 | 公開日 | 2002-03-20 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure of the 53BP1 BRCT region bound to p53 and its comparison to the Brca1 BRCT structure. Genes Dev., 16, 2002
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1LS8
| NMR structure of the unliganded Bombyx mori pheromone-binding protein at physiological pH | 分子名称: | pheromone binding protein | 著者 | Lee, D, Damberger, F, Horst, R, Guntert, P, Leal, W.S, Wuthrich, K. | 登録日 | 2002-05-17 | 公開日 | 2002-11-20 | 最終更新日 | 2022-02-23 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR structure of the unliganded Bombyx mori pheromone-binding protein at physiological pH FEBS Lett., 531, 2002
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1KZY
| Crystal Structure of the 53bp1 BRCT Region Complexed to Tumor Suppressor P53 | 分子名称: | CELLULAR TUMOR ANTIGEN P53, TUMOR SUPPRESSOR P53-BINDING PROTEIN 1, ZINC ION | 著者 | Joo, W.S, Jeffrey, P.D, Cantor, S.B, Finnin, M.S, Livingston, D.M, Pavletich, N.P. | 登録日 | 2002-02-08 | 公開日 | 2002-03-20 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structure of the 53BP1 BRCT region bound to p53 and its comparison to the Brca1 BRCT structure. Genes Dev., 16, 2002
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1MX6
| Structure of p18INK4c (F92N) | 分子名称: | Cyclin-dependent kinase 6 inhibitor | 著者 | Marmorstein, R, Venkataramani, R.N, MacLachlan, T.K, Chai, X, El-Deiry, W.S. | 登録日 | 2002-10-01 | 公開日 | 2002-10-16 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure-based design of p18INK4c proteins with increased thermodynamic stability and cell cycle inhibitory activity J.Biol.Chem., 277, 2002
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7KYQ
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7KYS
| Crystal structure of human BCCIP beta (Native2) | 分子名称: | 1,2-ETHANEDIOL, BRCA2 and CDKN1A-interacting protein, DI(HYDROXYETHYL)ETHER | 著者 | Choi, W.S, Liu, B, Shen, Z, Yang, W. | 登録日 | 2020-12-08 | 公開日 | 2021-06-09 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure of human BCCIP and implications for binding and modification of partner proteins. Protein Sci., 30, 2021
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1NY3
| Crystal structure of ADP bound to MAP KAP kinase 2 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAP kinase-activated protein kinase 2 | 著者 | Underwood, K.W, Parris, K.D, Federico, E, Mosyak, L, Shane, T, Taylor, M, Svenson, K, Liu, Y, Hsiao, C.L, Wolfrom, S, Maguire, M, Malakian, K, Telliez, J.B, Lin, L.L, Kriz, R.W, Seehra, J, Somers, W.S, Stahl, M.L. | 登録日 | 2003-02-11 | 公開日 | 2003-10-14 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Catalytically active MAP KAP kinase 2 structures in complex with staurosporine and ADP reveal differences with the autoinhibited enzyme Structure, 11, 2003
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1P8V
| CRYSTAL STRUCTURE OF THE COMPLEX OF PLATELET RECEPTOR GPIB-ALPHA AND ALPHA-THROMBIN AT 2.6A | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, DIISOPROPYL PHOSPHONATE, ... | 著者 | Dumas, J.J, Kumar, R, Seehra, J, Somers, W.S, Mosyak, L. | 登録日 | 2003-05-07 | 公開日 | 2003-07-22 | 最終更新日 | 2021-10-27 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal Structure of the GpIbalpha-Thrombin Complex Essential for Platelet Aggregation Science, 301, 2003
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7LBX
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7LBW
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1MUH
| CRYSTAL STRUCTURE OF TN5 TRANSPOSASE COMPLEXED WITH TRANSPOSON END DNA | 分子名称: | DNA NON-TRANSFERRED STRAND, DNA TRANSFERRED STRAND, MAGNESIUM ION, ... | 著者 | Thoden, J.B, Holden, H.M, Davies, D.R, Goryshin, I.Y, Reznikoff, W.S, Rayment, I. | 登録日 | 2002-09-23 | 公開日 | 2002-09-27 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Three-dimensional structure of the Tn5 synaptic complex transposition intermediate. Science, 289, 2000
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1MX4
| Structure of p18INK4c (F82Q) | 分子名称: | Cyclin-dependent kinase 6 inhibitor | 著者 | Marmorstein, R, Venkataramani, R.N, MacLachlan, T.K, Chai, X, El-Deiry, W.S. | 登録日 | 2002-10-01 | 公開日 | 2002-10-16 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure-based design of p18INK4c proteins with increased thermodynamic stability and cell cycle inhibitory activity J.Biol.Chem., 277, 2002
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1MUS
| crystal structure of Tn5 transposase complexed with resolved outside end DNA | 分子名称: | 1,2-ETHANEDIOL, DNA non-transferred strand, DNA transferred strand, ... | 著者 | Holden, H.M, Thoden, J.B, Steiniger-White, M, Reznikoff, W.S, Lovell, S, Rayment, I. | 登録日 | 2002-09-24 | 公開日 | 2002-09-27 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structure/function insights into Tn5 transposition. Curr.Opin.Struct.Biol., 14, 2004
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1NXK
| Crystal structure of staurosporine bound to MAP KAP kinase 2 | 分子名称: | MAP kinase-activated protein kinase 2, STAUROSPORINE, SULFATE ION | 著者 | Underwood, K.W, Parris, K.D, Federico, E, Mosyak, L, Czerwinski, R.M, Shane, T, Taylor, M, Svenson, K, Liu, Y, Hsiao, C.L, Wolfrom, S, Malakian, K, Telliez, J.B, Lin, L.L, Kriz, R.W, Seehra, J, Somers, W.S, Stahl, M.L. | 登録日 | 2003-02-10 | 公開日 | 2003-10-14 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Catalytically active MAP KAP kinase 2 structures in complex with staurosporine and ADP reveal differences with the autoinhibited enzyme Structure, 11, 2003
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1MM8
| Crystal structure of Tn5 Transposase complexed with ME DNA | 分子名称: | MANGANESE (II) ION, ME DNA non-transferred strand, ME DNA transferred strand, ... | 著者 | Steiniger-White, M, Bhasin, A, Lovell, S, Rayment, I, Reznikoff, W.S. | 登録日 | 2002-09-03 | 公開日 | 2002-12-13 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Evidence for "unseen" Transposase--DNA contacts J.Mol.Biol., 322, 2002
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7KQN
| Ternary complex of TERT (telomerase reverse transcriptase) with RNA template, DNA primer, an incoming dGTP and a downstream hybrid duplex | 分子名称: | 1,2-ETHANEDIOL, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... | 著者 | Choi, W.S, Weng, P.J, Yang, W. | 登録日 | 2020-11-17 | 公開日 | 2022-03-23 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | Flexibility of telomerase in binding the RNA template and DNA telomeric repeat. Proc.Natl.Acad.Sci.USA, 119, 2022
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7KQM
| Binary complex of TERT (telomerase reverse transcriptase) with RNA/telomeric DNA hybrid | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, DNA (5'-D(*TP*TP*CP*TP*TP*TP*GP*TP*GP*CP*AP*CP*CP*TP*G)-3'), ... | 著者 | Choi, W.S, Weng, P.J, Yang, W. | 登録日 | 2020-11-17 | 公開日 | 2022-03-23 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.73 Å) | 主引用文献 | Flexibility of telomerase in binding the RNA template and DNA telomeric repeat. Proc.Natl.Acad.Sci.USA, 119, 2022
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1PU9
| Crystal Structure of Tetrahymena GCN5 with Bound Coenzyme A and a 19-residue Histone H3 Peptide | 分子名称: | COENZYME A, HAT A1, Histone H3 | 著者 | Clements, A, Poux, A.N, Lo, W.S, Pillus, L, Berger, S.L, Marmorstein, R. | 登録日 | 2003-06-24 | 公開日 | 2003-09-23 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural basis for histone and phospho-histone binding by the GCN5 histone acetyltransferase Mol.Cell, 12, 2003
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1PUA
| Crystal Structure of Tetrahymena GCN5 with Bound Coenzyme A and a Phosphorylated, 19-residue Histone H3 peptide | 分子名称: | COENZYME A, HAT A1, Histone H3 | 著者 | Clements, A, Poux, A.N, Lo, W.S, Pillus, L, Berger, S.L, Marmorstein, R. | 登録日 | 2003-06-24 | 公開日 | 2003-09-23 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural basis for histone and phospho-histone binding by the GCN5 histone acetyltransferase Mol.Cell, 12, 2003
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1Q6Q
| Structure of 3-keto-L-gulonate 6-phosphate decarboxylase with bound xylitol 5-phosphate | 分子名称: | 3-keto-L-gulonate 6-phosphate decarboxylase, L-XYLITOL 5-PHOSPHATE, MAGNESIUM ION | 著者 | Wise, E.L, Yew, W.S, Gerlt, J.A, Rayment, I. | 登録日 | 2003-08-13 | 公開日 | 2003-10-28 | 最終更新日 | 2019-07-24 | 実験手法 | X-RAY DIFFRACTION (1.695 Å) | 主引用文献 | Structural Evidence for a 1,2-Enediolate Intermediate in the Reaction Catalyzed by 3-Keto-l-Gulonate 6-Phosphate Decarboxylase, a Member of the Orotidine 5'-Monophosphate Decarboxylase Suprafamily Biochemistry, 42, 2003
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1Q6O
| Structure of 3-keto-L-gulonate 6-phosphate decarboxylase with bound L-gulonaet 6-phosphate | 分子名称: | 3-keto-L-gulonate 6-phosphate decarboxylase, L-GULURONIC ACID 6-PHOSPHATE, MAGNESIUM ION | 著者 | Wise, E.L, Yew, W.S, Gerlt, J.A, Rayment, I. | 登録日 | 2003-08-13 | 公開日 | 2003-10-28 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.202 Å) | 主引用文献 | Structural Evidence for a 1,2-Enediolate Intermediate in the Reaction Catalyzed by 3-Keto-l-Gulonate 6-Phosphate Decarboxylase, a Member of the Orotidine 5'-Monophosphate Decarboxylase Suprafamily Biochemistry, 42, 2003
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1Q6R
| Structure of 3-keto-L-gulonate 6-phosphate decarboxylase with bound L-xylulose 5-phosphate | 分子名称: | 3-keto-L-gulonate 6-phosphate decarboxylase, L-XYLULOSE 5-PHOSPHATE, MAGNESIUM ION | 著者 | Wise, E.L, Yew, W.S, Gerlt, J.A, Rayment, I. | 登録日 | 2003-08-13 | 公開日 | 2003-10-28 | 最終更新日 | 2019-07-24 | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | 主引用文献 | Structural Evidence for a 1,2-Enediolate Intermediate in the Reaction Catalyzed by 3-Keto-l-Gulonate 6-Phosphate Decarboxylase, a Member of the Orotidine 5'-Monophosphate Decarboxylase Suprafamily Biochemistry, 42, 2003
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