4R5Y
| The complex structure of Braf V600E kinase domain with a novel Braf inhibitor | 分子名称: | 5-({(1R,1aS,6bR)-1-[5-(trifluoromethyl)-1H-benzimidazol-2-yl]-1a,6b-dihydro-1H-cyclopropa[b][1]benzofuran-5-yl}oxy)-3,4-dihydro-1,8-naphthyridin-2(1H)-one, Serine/threonine-protein kinase B-raf | 著者 | Feng, Y, Peng, H, Zhang, Y, Liu, Y, Wei, M. | 登録日 | 2014-08-22 | 公開日 | 2016-02-24 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | BGB-283, a Novel RAF Kinase and EGFR Inhibitor, Displays Potent Antitumor Activity in BRAF-Mutated Colorectal Cancers. Mol.Cancer Ther., 14, 2015
|
|
4IH1
| Crystal structure of Karrikin Insensitive 2 (KAI2) from Arabidopsis thaliana | 分子名称: | Hydrolase, alpha/beta fold family protein | 著者 | Zhou, X.E, Zhao, L.-H, Wu, Z.-S, Yi, W, Li, S, Li, Y, Xu, Y, Xu, T.-H, Liu, Y, Chen, R.-Z, Kovach, A, Kang, Y, Hou, L, He, Y, Zhang, C, Melcher, K, Xu, H.E. | 登録日 | 2012-12-18 | 公開日 | 2013-01-30 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Crystal structures of two phytohormone signal-transducing alpha / beta hydrolases: karrikin-signaling KAI2 and strigolactone-signaling DWARF14. Cell Res., 23, 2013
|
|
4IH9
| Crystal structure of rice DWARF14 (D14) | 分子名称: | Dwarf 88 esterase | 著者 | Zhou, X.E, Zhao, L.-H, Wu, Z.-S, Yi, W, Li, S, Li, Y, Xu, Y, Xu, T.-H, Liu, Y, Chen, R.-Z, Kovach, A, Kang, Y, Hou, L, He, Y, Zhang, C, Melcher, K, Xu, H.E. | 登録日 | 2012-12-18 | 公開日 | 2013-01-30 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Crystal structures of two phytohormone signal-transducing alpha / beta hydrolases: karrikin-signaling KAI2 and strigolactone-signaling DWARF14. Cell Res., 23, 2013
|
|
5DJ5
| Crystal structure of rice DWARF14 in complex with synthetic strigolactone GR24 | 分子名称: | (3E,3aR,8bS)-3-({[(2R)-4-methyl-5-oxo-2,5-dihydrofuran-2-yl]oxy}methylidene)-3,3a,4,8b-tetrahydro-2H-indeno[1,2-b]furan-2-one, Probable strigolactone esterase D14 | 著者 | Zhou, X.E, Zhao, L.-H, Yi, W, Wu, Z.-S, Liu, Y, Kang, Y, Hou, L, de Waal, P.W, Li, S, Jiang, Y, Melcher, K, Xu, H.E. | 登録日 | 2015-09-01 | 公開日 | 2015-10-28 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Destabilization of strigolactone receptor DWARF14 by binding of ligand and E3-ligase signaling effector DWARF3. Cell Res., 25, 2015
|
|
4IHA
| Crystal structure of rice DWARF14 (D14) in complex with a GR24 hydrolysis intermediate | 分子名称: | (2R,3R)-2,4,4-trihydroxy-3-methylbutanal, Dwarf 88 esterase | 著者 | Zhou, X.E, Zhao, L.-H, Wu, Z.-S, Yi, W, Li, S, Li, Y, Xu, Y, Xu, T.-H, Liu, Y, Chen, R.-Z, Kovach, A, Kang, Y, Hou, L, He, Y, Zhang, C, Melcher, K, Xu, H.E. | 登録日 | 2012-12-18 | 公開日 | 2013-01-23 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Crystal structures of two phytohormone signal-transducing alpha / beta hydrolases: karrikin-signaling KAI2 and strigolactone-signaling DWARF14. Cell Res., 23, 2013
|
|
4IH4
| Crystal structure of Arabidopsis DWARF14 orthologue, AtD14 | 分子名称: | AT3g03990/T11I18_10 | 著者 | Zhou, X.E, Zhao, L.-H, Wu, Z.-S, Yi, W, Li, S, Li, Y, Xu, Y, Xu, T.-H, Liu, Y, Chen, R.-Z, Kovach, A, Kang, Y, Hou, L, He, Y, Zhang, C, Melcher, K, Xu, H.E. | 登録日 | 2012-12-18 | 公開日 | 2013-01-30 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Crystal structures of two phytohormone signal-transducing alpha / beta hydrolases: karrikin-signaling KAI2 and strigolactone-signaling DWARF14. Cell Res., 23, 2013
|
|
6VZU
| TTLL6 bound to alpha-elongation analog | 分子名称: | (2~{S})-2-[[[(1~{R})-1-acetamido-4-oxidanyl-4-oxidanylidene-butyl]-oxidanyl-phosphoryl]methyl]pentanedioic acid, (2~{S})-2-[[[(1~{R})-1-acetamido-4-oxidanyl-4-oxidanylidene-butyl]-phosphonooxy-phosphoryl]methyl]pentanedioic acid, ADENOSINE-5'-DIPHOSPHATE, ... | 著者 | Mahalingan, K.K, Keenen, E.K, Strickland, M, Li, Y, Liu, Y, Ball, H.B, Tanner, M.E, Tjandra, N, Roll-Mecak, A. | 登録日 | 2020-02-28 | 公開日 | 2020-08-12 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Structural basis for polyglutamate chain initiation and elongation by TTLL family enzymes. Nat.Struct.Mol.Biol., 27, 2020
|
|
6VZQ
| Engineered TTLL6 mutant bound to alpha-elongation analog | 分子名称: | (2~{S})-2-[[[(1~{R})-1-acetamido-4-oxidanyl-4-oxidanylidene-butyl]-phosphonooxy-phosphoryl]methyl]pentanedioic acid, (2~{S})-2-[[[(1~{S})-1-acetamidoethyl]-phosphonooxy-phosphoryl]methyl]pentanedioic acid, ADENOSINE-5'-DIPHOSPHATE, ... | 著者 | Mahalingan, K.K, Keenen, E.K, Strickland, E.K, Li, Y, Liu, Y, Ball, H.L, Tanner, M.E, Tjandra, N, Roll-Mecak, A. | 登録日 | 2020-02-28 | 公開日 | 2020-08-12 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.08 Å) | 主引用文献 | Structural basis for polyglutamate chain initiation and elongation by TTLL family enzymes. Nat.Struct.Mol.Biol., 27, 2020
|
|
6VZT
| TTLL6 bound to ATP | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... | 著者 | Mahalingan, K.K, Keenen, E.K, Strickland, M, Li, Y, Liu, Y, Ball, H.L, Tanner, M.E, Tjandra, N, Roll-Mecak, A. | 登録日 | 2020-02-28 | 公開日 | 2020-08-12 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | 主引用文献 | Structural basis for polyglutamate chain initiation and elongation by TTLL family enzymes. Nat.Struct.Mol.Biol., 27, 2020
|
|
6VZV
| TTLL6 bound to gamma-elongation analog | 分子名称: | (2~{S})-2-[[[(3~{R})-3-acetamido-4-oxidanyl-4-oxidanylidene-butyl]-phosphonooxy-phosphoryl]methyl]pentanedioic acid, (2~{S})-2-[[[(3~{S})-3-acetamido-4-oxidanyl-4-oxidanylidene-butyl]-oxidanyl-phosphoryl]methyl]pentanedioic acid, ADENOSINE-5'-DIPHOSPHATE, ... | 著者 | Mahalingan, K.K, Keenen, E.K, Strickland, M, Li, Y, Liu, Y, Ball, H.L, Tanner, M.E, Tjandra, N, Roll-Mecak, A. | 登録日 | 2020-02-28 | 公開日 | 2020-08-12 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | 主引用文献 | Structural basis for polyglutamate chain initiation and elongation by TTLL family enzymes. Nat.Struct.Mol.Biol., 27, 2020
|
|
6VZR
| Engineered TTLL6 bound to the initiation analog | 分子名称: | (2~{S})-2-[[[(3~{R})-3-acetamido-4-(ethylamino)-4-oxidanylidene-butyl]-phosphonooxy-phosphoryl]methyl]pentanedioic acid, ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, ... | 著者 | Mahalingan, K.K, Keenen, E.K, Strickland, M, Li, Y, Liu, Y, Ball, H.L, Tanner, M.E, Tjandra, N, Roll-Mecak, A. | 登録日 | 2020-02-28 | 公開日 | 2020-08-12 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural basis for polyglutamate chain initiation and elongation by TTLL family enzymes. Nat.Struct.Mol.Biol., 27, 2020
|
|
8TJP
| KS-AT core of 6-deoxyerythronolide B synthase (DEBS) Module 3 crosslinked with its elongation ACP partner | 分子名称: | EryAII | 著者 | Cogan, D.P, Soohoo, A.M, Chen, M, Brodsky, K.L, Liu, Y, Khosla, C. | 登録日 | 2023-07-23 | 公開日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (3.71 Å) | 主引用文献 | Structural Basis for Intermodular Communication in Assembly-Line Polyketide Biosynthesis To Be Published
|
|
3EBJ
| Crystal structure of an avian influenza virus protein | 分子名称: | MAGNESIUM ION, Polymerase acidic protein | 著者 | Yuan, P, Bartlam, M, Lou, Z, Chen, S, Rao, Z, Liu, Y. | 登録日 | 2008-08-27 | 公開日 | 2009-02-10 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structure of an avian influenza polymerase PA(N) reveals an endonuclease active site Nature, 458, 2009
|
|
8TJO
| Crosslinked 6-deoxyerythronolide B synthase (DEBS) Module 1 in complex with antibody fragment 1B2: Crosslinked Intra-State 1 | 分子名称: | Antibody Fragment 1B2, Heavy Chain, Light Chain, ... | 著者 | Cogan, D.P, Soohoo, A.M, Chen, M, Brodsky, K.L, Liu, Y, Khosla, C. | 登録日 | 2023-07-23 | 公開日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (3.61 Å) | 主引用文献 | Structural Basis for Intermodular Communication in Assembly-Line Polyketide Biosynthesis To Be Published
|
|
3ERW
| Crystal Structure of StoA from Bacillus subtilis | 分子名称: | Sporulation thiol-disulfide oxidoreductase A | 著者 | Crow, A, Liu, Y, Moller, M.C, Le Brun, N.E, Hederstedt, L. | 登録日 | 2008-10-03 | 公開日 | 2009-01-20 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structure and Functional Properties of Bacillus subtilis Endospore Biogenesis Factor StoA J.Biol.Chem., 284, 2009
|
|
8TJN
| Crosslinked 6-deoxyerythronolide B synthase (DEBS) Module 1 in complex with antibody fragment 1B2: Crosslinked State 1 | 分子名称: | Antibody Fragment 1B2, Heavy Chain, Light Chain, ... | 著者 | Cogan, D.P, Soohoo, A.M, Chen, M, Brodsky, K.L, Liu, Y, Khosla, C. | 登録日 | 2023-07-23 | 公開日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (3.73 Å) | 主引用文献 | Structural Basis for Intermodular Communication in Assembly-Line Polyketide Biosynthesis To Be Published
|
|
8TGZ
| CryoEM structure of neutralizing antibody HC84.26 in complex with Hepatitis C virus envelope glycoprotein E2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HC84.26 Heavy chain, ... | 著者 | Shahid, S, Liqun, J, Liu, Y, Hasan, S.S, Mariuzza, R.A. | 登録日 | 2023-07-13 | 公開日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (3.78 Å) | 主引用文献 | CryoEM structure of neutralizing antibody HC84.26 in complex with Hepatitis C virus envelope glycoprotein E2 To Be Published
|
|
8THZ
| CryoEM structure of neutralizing antibodies CBH-7 and HC84.26 in complex with Hepatitis C virus envelope glycoprotein E2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CBH-7 Heavy chain, ... | 著者 | Shahid, S, Jiang, L, Liu, Y, Hasan, S.S, Mariuzza, R.A. | 登録日 | 2023-07-18 | 公開日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (3.25 Å) | 主引用文献 | CryoEM structure of neutralizing antibodies CBH-7 and HC84.26 in complex with Hepatitis C virus envelope glycoprotein E2 To Be Published
|
|
8TGV
| CryoEM structure of Fab HC84.26-HCV E2 complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HC84.26 Heavy chain, ... | 著者 | Shahid, S, Liqun, J, LIu, Y, Hasan, S.S, Mariuzza, R.A. | 登録日 | 2023-07-13 | 公開日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (3.75 Å) | 主引用文献 | CryoEM structure of Fab HC84.26-HCV E2 complex To Be Published
|
|
1T1J
| Crystal structure of genomics APC5043 | 分子名称: | hypothetical protein | 著者 | Dong, A, Xu, X, Liu, Y, Zhang, R, Savchenko, A, Edwards, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2004-04-16 | 公開日 | 2004-08-03 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystal Structure of Conserved Hypothetical Protein PA1492 from Pseudomonas aeruginosa TO BE PUBLISHED
|
|
5D87
| Staphyloferrin B precursor biosynthetic enzyme SbnA Y152F/S185G variant | 分子名称: | MAGNESIUM ION, POTASSIUM ION, PYRIDOXAL-5'-PHOSPHATE, ... | 著者 | Kobylarz, M.J, Grigg, J.C, Liu, Y, Lee, M.S.F, Heinrichs, D.E, Murphy, M.E.P. | 登録日 | 2015-08-15 | 公開日 | 2016-02-03 | 最終更新日 | 2020-01-08 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Deciphering the Substrate Specificity of SbnA, the Enzyme Catalyzing the First Step in Staphyloferrin B Biosynthesis. Biochemistry, 55, 2016
|
|
5D85
| Staphyloferrin B precursor biosynthetic enzyme SbnA bound to aminoacrylate intermediate | 分子名称: | 2-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]ACRYLIC ACID, CITRATE ANION, GLYCEROL, ... | 著者 | Kobylarz, M.J, Grigg, J.C, Liu, Y, Lee, M.S.F, Heinrichs, D.E, Murphy, M.E.P. | 登録日 | 2015-08-15 | 公開日 | 2016-02-03 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | Deciphering the Substrate Specificity of SbnA, the Enzyme Catalyzing the First Step in Staphyloferrin B Biosynthesis. Biochemistry, 55, 2016
|
|
5D86
| Staphyloferrin B precursor biosynthetic enzyme SbnA Y152F variant | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, MAGNESIUM ION, PYRIDOXAL-5'-PHOSPHATE, ... | 著者 | Kobylarz, M.J, Grigg, J.C, Liu, Y, Lee, M.S.F, Heinrichs, D.E, Murphy, M.E.P. | 登録日 | 2015-08-15 | 公開日 | 2016-02-03 | 最終更新日 | 2020-01-08 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Deciphering the Substrate Specificity of SbnA, the Enzyme Catalyzing the First Step in Staphyloferrin B Biosynthesis. Biochemistry, 55, 2016
|
|
8I3X
| Rice APIP6-RING homodimer | 分子名称: | RING-type domain-containing protein, ZINC ION | 著者 | Zheng, Y, Zhang, X, Liu, Y, Liu, J, Wang, D. | 登録日 | 2023-01-18 | 公開日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | 主引用文献 | Crystal structure of rice APIP6 reveals a new dimerization mode of RING-type E3 ligases that facilities the construction of its working model Phytopathol Res, 5, 2023
|
|
6R47
| |