8TJO

Crosslinked 6-deoxyerythronolide B synthase (DEBS) Module 1 in complex with antibody fragment 1B2: Crosslinked Intra-State 1

Summary for 8TJO

• Entry DOI: 10.2210/pdb8tjo/pdb
• EMDB information: 41305 41306 41307
• Descriptor: EryAI,6-deoxyerythronolide-B synthase EryA3, modules 5 and 6, Antibody Fragment 1B2, Heavy Chain, Antibody Fragment 1B2, Light Chain (3 entities in total)
• Functional Keywords: polyketide synthase, antibody, biosynthetic protein-immune system complex, biosynthetic protein/immune system
• Biological source: Saccharopolyspora erythraea; More
• Total number of polymer chains: 6
• Total formula weight: 482109.32

Authors

Cogan, D.P.,Soohoo, A.M.,Chen, M.,Brodsky, K.L.,Liu, Y.,Khosla, C. (deposition date: 2023-07-23, release date: 2024-07-24)

• Primary citation: Cogan, D.P.,Soohoo, A.M.,Chen, M.,Liu, Y.,Brodsky, K.L.,Khosla, C.; Structural Basis for Intermodular Communication in Assembly-Line Polyketide Biosynthesis; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.61 Å)