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7EIG
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BU of 7eig by Molmil
BRD4-BD1 in complex with LT-730-903
分子名称: 1-[5-(5-azanyl-1H-benzimidazol-2-yl)-2-methyl-4-phenyl-1H-pyrrol-3-yl]ethanone, Bromodomain-containing protein 4
著者Zheng, W, Kong, B, Tang, W, Zhu, J, Chen, Y.
登録日2021-03-31
公開日2022-04-06
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献BRD4-BD1 in complex with LT-730-903
To Be Published
7EIK
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BU of 7eik by Molmil
RD4-BD1 in complex with LT-872-297
分子名称: 1-[2-methyl-5-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-4-(1-methylpyrazol-4-yl)-1H-pyrrol-3-yl]ethanone, Bromodomain-containing protein 4
著者Zheng, W, Kong, B, Tang, W, Zhu, J, Chen, Y.
登録日2021-03-31
公開日2022-04-06
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献RD4-BD1 in complex with LT-872-297
To Be Published
7CSP
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BU of 7csp by Molmil
Structure of Ephexin4 IDPSH
分子名称: Rho guanine nucleotide exchange factor 16
著者Zhang, M, Lin, L, Wang, C, Zhu, J.
登録日2020-08-15
公開日2021-02-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Double inhibition and activation mechanisms of Ephexin family RhoGEFs.
Proc.Natl.Acad.Sci.USA, 118, 2021
7CSR
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BU of 7csr by Molmil
Structure of Ephexin4 R676L
分子名称: Rho guanine nucleotide exchange factor 16
著者Zhang, M, Lin, L, Wang, C, Zhu, J.
登録日2020-08-17
公開日2021-02-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Double inhibition and activation mechanisms of Ephexin family RhoGEFs.
Proc.Natl.Acad.Sci.USA, 118, 2021
7CSO
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BU of 7cso by Molmil
Structure of Ephexin4 DH-PH-SH3
分子名称: Rho guanine nucleotide exchange factor 16, SULFATE ION
著者Zhang, M, Lin, L, Wang, C, Zhu, J.
登録日2020-08-15
公開日2021-02-24
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Double inhibition and activation mechanisms of Ephexin family RhoGEFs.
Proc.Natl.Acad.Sci.USA, 118, 2021
7EP7
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BU of 7ep7 by Molmil
The complex structure of Gpsm2 and Whirlin
分子名称: G-protein-signaling modulator 2, Whirlin
著者Lin, L, Shi, Y, Wang, C, Zhu, J.
登録日2021-04-26
公開日2022-05-04
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Promotion of row 1-specific tip complex condensates by Gpsm2-G alpha i provides insights into row identity of the tallest stereocilia.
Sci Adv, 8, 2022
2LIT
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BU of 2lit by Molmil
NMR Solution Structure of Yeast Iso-1-cytochrome c Mutant P71H in reduced states
分子名称: Cytochrome c iso-1, HEME C
著者Lan, W, Wang, Z, Yang, Z, Zhu, J, Ying, T, Jiang, X, Zhang, X, Wu, H, Liu, M, Tan, X, Cao, C, Huang, Z.X.
登録日2011-08-31
公開日2011-12-07
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Conformational toggling of yeast iso-1-cytochrome C in the oxidized and reduced States.
Plos One, 6, 2011
2LIR
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BU of 2lir by Molmil
NMR Solution Structure of Yeast Iso-1-cytochrome c Mutant P71H in oxidized states
分子名称: Cytochrome c iso-1, HEME C
著者Lan, W, Wang, Z, Yang, Z, Zhu, J, Ying, T, Jiang, X, Zhang, X, Wu, H, Liu, M, Tan, X, Cao, C, Huang, Z.X.
登録日2011-08-31
公開日2011-12-07
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Conformational toggling of yeast iso-1-cytochrome C in the oxidized and reduced States.
Plos One, 6, 2011
7L83
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BU of 7l83 by Molmil
NMR solution structure of Nav1.5 DIV S3b-S4a paddle motif in DPC micelle
分子名称: Sodium channel protein type 5 subunit alpha
著者Hussein, A.K, Bhuiyan, M.H, Arshava, B, Zhuang, J, Poget, S.F.
登録日2020-12-30
公開日2021-06-02
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献NMR solution structure and analysis of isolated S3b-S4a motif of repeat IV of the human cardiac sodium channel
Biorxiv, 2021
7W80
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BU of 7w80 by Molmil
Crystal Structure of the Heterodimeric HIF-2 in Complex with Antagonist Belzutifan
分子名称: 3-{[(1S,2S,3R)-2,3-difluoro-1-hydroxy-7-(methylsulfonyl)-2,3-dihydro-1H-inden-4-yl]oxy}-5-fluorobenzonitrile, Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1
著者Ren, X, Diao, X, Zhuang, J, Wu, D.
登録日2021-12-07
公開日2022-09-21
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.754 Å)
主引用文献Structural basis for the allosteric inhibition of hypoxia-inducible factor (HIF)-2 by belzutifan.
Mol.Pharmacol., 2022
3NIG
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BU of 3nig by Molmil
The Closed Headpiece of Integrin IIb 3 and its Complex with an IIb 3 -Specific Antagonist That Does Not Induce Opening
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Zhu, J.H, Zhu, J.Q, Springer, T.A.
登録日2010-06-15
公開日2010-12-22
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Closed headpiece of integrin {alpha}IIb{beta}3 and its complex with an {alpha}IIb{beta}3-specific antagonist that does not induce opening.
Blood, 116, 2010
3NIF
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BU of 3nif by Molmil
The Closed Headpiece of Integrin IIb 3 and its Complex with an IIb 3 -Specific Antagonist That Does Not Induce Opening
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-ethyl-7-piperazin-1-yl-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one, ...
著者Zhu, J.H, Zhu, J.Q, Springer, T.A.
登録日2010-06-15
公開日2010-12-22
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Closed headpiece of integrin {alpha}IIb{beta}3 and its complex with an {alpha}IIb{beta}3-specific antagonist that does not induce opening.
Blood, 116, 2010
5EIC
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BU of 5eic by Molmil
Crystal structure of the bromodomain of human CREBBP in complex with AYC
分子名称: 1,2-ETHANEDIOL, 2-[(chloroacetyl)amino]-5-[(E)-(4-sulfophenyl)diazenyl]benzenesulfonic acid, CREB-binding protein
著者Dong, J, Caflisch, A.
登録日2015-10-29
公開日2016-11-16
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Binding Motifs in the CBP Bromodomain: An Analysis of 20 Crystal Structures of Complexes with Small Molecules.
ACS Med Chem Lett, 9, 2018
5ENG
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BU of 5eng by Molmil
Crystal structure of the bromodomain of human CREBBP in complex with UP39
分子名称: CREB-binding protein, methyl 2-[2-(3,5-dihydro-2~{H}-pyrazin-4-yl)ethoxy]-5-[(5-ethanoyl-2-ethoxy-phenyl)carbamoyl]benzoate
著者Dong, J, Caflisch, A.
登録日2015-11-09
公開日2016-11-23
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Binding Motifs in the CBP Bromodomain: An Analysis of 20 Crystal Structures of Complexes with Small Molecules.
ACS Med Chem Lett, 9, 2018
5EP7
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BU of 5ep7 by Molmil
Crystal structure of the bromodomain of human CREBBP in complex with UN32
分子名称: 3-[(1-methyl-6-oxidanylidene-pyridin-3-yl)carbonylamino]benzoic acid, CREB-binding protein
著者Dong, J, Caflisch, A.
登録日2015-11-11
公開日2016-11-23
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.198 Å)
主引用文献Binding Motifs in the CBP Bromodomain: An Analysis of 20 Crystal Structures of Complexes with Small Molecules.
ACS Med Chem Lett, 9, 2018
3ZDY
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BU of 3zdy by Molmil
Integrin alphaIIB beta3 headpiece and RGD peptide complex
分子名称: 10E5 FAB HEAVY CHAIN, 10E5 FAB LIGHT CHAIN, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Zhu, J.H, Zhu, J.Q, Springer, T.A.
登録日2012-12-03
公開日2013-06-05
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Complete Integrin Headpiece Opening in Eight Steps.
J.Cell Biol., 201, 2013
3ZE2
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BU of 3ze2 by Molmil
Integrin alphaIIB beta3 headpiece and RGD peptide complex
分子名称: 10E5 FAB HEAVY CHAIN, 10E5 FAB LIGHT CHAIN, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Zhu, J.H, Zhu, J.Q, Springer, T.A.
登録日2012-12-03
公開日2013-06-05
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Complete Integrin Headpiece Opening in Eight Steps.
J.Cell Biol., 201, 2013
3ZE0
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BU of 3ze0 by Molmil
Integrin alphaIIB beta3 headpiece and RGD peptide complex
分子名称: 10E5 FAB HEAVY CHAIN, 10E5 FAB LIGHT CHAIN, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Zhu, J.H, Zhu, J.Q, Springer, T.A.
登録日2012-12-03
公開日2013-06-05
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Complete Integrin Headpiece Opening in Eight Steps.
J.Cell Biol., 201, 2013
3ZDZ
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BU of 3zdz by Molmil
Integrin alphaIIB beta3 headpiece and RGD peptide complex
分子名称: 10E5 FAB HEAVY CHAIN, 10E5 FAB LIGHT CHAIN, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Zhu, J.H, Zhu, J.Q, Springer, T.A.
登録日2012-12-03
公開日2013-06-05
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Complete Integrin Headpiece Opening in Eight Steps.
J.Cell Biol., 201, 2013
3ZDX
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BU of 3zdx by Molmil
Integrin alphaIIB beta3 headpiece and RGD peptide complex
分子名称: 10E5 FAB, HEAVY CHAIN, LIGHT CHAIN, ...
著者Zhu, J.H, Zhu, J.Q, Springer, T.A.
登録日2012-12-03
公開日2013-06-05
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Complete Integrin Headpiece Opening in Eight Steps.
J.Cell Biol., 201, 2013
3ZE1
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BU of 3ze1 by Molmil
Integrin alphaIIB beta3 headpiece and RGD peptide complex
分子名称: 10E5 FAB HEAVY CHAIN, 10E5 FAB LIGHT CHAIN, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Zhu, J.H, Zhu, J.Q, Springer, T.A.
登録日2012-12-03
公開日2013-06-05
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Complete Integrin Headpiece Opening in Eight Steps.
J.Cell Biol., 201, 2013
7T62
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BU of 7t62 by Molmil
GPC2 HEP CT3 complex
分子名称: CT3, Glypican-2
著者Zhu, J, Cachau, R, De Val Alda, N, Li, N, Ho, M.
登録日2021-12-13
公開日2021-12-22
実験手法ELECTRON MICROSCOPY (21 Å)
主引用文献CAR T cells targeting tumor-associated exons of glypican 2 regress neuroblastoma in mice.
Cell Rep Med, 2, 2021
5NGH
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BU of 5ngh by Molmil
Structure of Odorant Binding Protein 3 from Giant Panda (Ailuropoda melanoleuca)
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Odorant Binding Protein 3
著者Cambillau, C, Spinelli, S, Pelosi, P.
登録日2017-03-17
公開日2017-11-01
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Reverse chemical ecology: Olfactory proteins from the giant panda and their interactions with putative pheromones and bamboo volatiles.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
3RO2
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BU of 3ro2 by Molmil
Structures of the LGN/NuMA complex
分子名称: G-protein-signaling modulator 2, GLYCEROL, peptide of Nuclear mitotic apparatus protein 1
著者Shang, Y, Wei, Z.
登録日2011-04-25
公開日2012-03-07
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献LGN/mInsc and LGN/NuMA complex structures suggest distinct functions in asymmetric cell division for the Par3/mInsc/LGN and G[alpha]i/LGN/NuMA pathways
Mol.Cell, 43, 2011
5H85
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BU of 5h85 by Molmil
Crystal structure of the bromodomain of human CREBBP in complex with UO37D
分子名称: CREB-binding protein, methyl 3-(7~{H}-purin-6-ylcarbamoyl)benzoate
著者Dong, J, Caflisch, A.
登録日2015-12-23
公開日2017-01-11
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.701 Å)
主引用文献Binding Motifs in the CBP Bromodomain: An Analysis of 20 Crystal Structures of Complexes with Small Molecules.
ACS Med Chem Lett, 9, 2018

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