1TKX
 
 | | CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH GW490745 | | 分子名称: | 4-[(CYCLOPROPYLETHYNYL)OXY]-6-FLUORO-3-ISOPROPYLQUINOLIN-2(1H)-ONE, Pol polyprotein, Reverse transcriptase, ... | | 著者 | Ren, J, Hopkins, A.L, Stuart, D.I, Stammers, D.K. | | 登録日 | 2004-06-09 | | 公開日 | 2004-12-07 | | 最終更新日 | 2022-12-21 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Design of non-nucleoside inhibitors of HIV-1 reverse transcriptase with improved drug resistance properties. 2.
J.Med.Chem., 47, 2004
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7PWJ
 | | dUTPase from human in complex with Stl | | 分子名称: | 1,2-ETHANEDIOL, Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial, ... | | 著者 | Sanz-Frasquet, C, Marina, A. | | 登録日 | 2021-10-06 | | 公開日 | 2022-12-28 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.944 Å) | | 主引用文献 | The Bacteriophage-Phage-Inducible Chromosomal Island Arms Race Designs an Interkingdom Inhibitor of dUTPases.
Microbiol Spectr, 11, 2023
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7PWX
 | | dUTPase from M. tuberculosis in complex with Stl | | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Marina, A, Sanz-Frasquet, C. | | 登録日 | 2021-10-07 | | 公開日 | 2022-12-28 | | 最終更新日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | The Bacteriophage-Phage-Inducible Chromosomal Island Arms Race Designs an Interkingdom Inhibitor of dUTPases.
Microbiol Spectr, 11, 2023
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6YHR
 | | Crystal structure of Werner syndrome helicase | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Werner syndrome ATP-dependent helicase, ZINC ION | | 著者 | Newman, J.A, Gavard, A.E, Savitsky, P, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. | | 登録日 | 2020-03-30 | | 公開日 | 2020-04-29 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure of the helicase core of Werner helicase, a key target in microsatellite instability cancers.
Life Sci Alliance, 4, 2021
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8B01
 | | Cryo-EM structure of the Tripartite ATP-independent Periplasmic (TRAP) transporter SiaQM from Photobacterium profundum in a nanodisc | | 分子名称: | DECANE, DOCOSANE, HEXANE, ... | | 著者 | Davies, J.S, North, R.A, Dobson, R.C.J. | | 登録日 | 2022-09-06 | | 公開日 | 2023-03-15 | | 実験手法 | ELECTRON MICROSCOPY (3.03 Å) | | 主引用文献 | Structure and mechanism of a tripartite ATP-independent periplasmic TRAP transporter.
Nat Commun, 14, 2023
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6YKG
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8AFI
 | | GABARAP in complex with LIR motif of HsATG3 | | 分子名称: | ACETATE ION, GLYCEROL, Gamma-aminobutyric acid receptor-associated protein, ... | | 著者 | Farnung, J, Benoit, R.M, Corn, J.E, Bode, J.W. | | 登録日 | 2022-07-18 | | 公開日 | 2023-05-10 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.66 Å) | | 主引用文献 | Semisynthetic LC3 Probes for Autophagy Pathways Reveal a Noncanonical LC3 Interacting Region Motif Crucial for the Enzymatic Activity of Human ATG3.
Acs Cent.Sci., 9, 2023
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8AW0
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8AVZ
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5U3O
 | | Crystal Structure of DH511.2_K3 Fab in Complex with HIV-1 gp41 MPER Peptide | | 分子名称: | DH511.2_K3 Fab Heavy Chain, DH511.2_K3 Fab Light Chain, gp41 MPER peptide | | 著者 | Ofek, G, Wu, L, Lougheed, C.S, Williams, L.D, Nicely, N.I, Haynes, B.F. | | 登録日 | 2016-12-02 | | 公開日 | 2017-02-15 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.761 Å) | | 主引用文献 | Potent and broad HIV-neutralizing antibodies in memory B cells and plasma.
Sci Immunol, 2, 2017
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5U3K
 | | Crystal Structure of DH511.2 Fab in Complex with HIV-1 gp41 MPER 662-683 Peptide | | 分子名称: | CALCIUM ION, CHLORIDE ION, DH511.2 Fab Heavy Chain, ... | | 著者 | Ofek, G, Wu, L, Lougheed, C.S, Williams, L.D, Nicely, N.I, Haynes, B.F. | | 登録日 | 2016-12-02 | | 公開日 | 2017-02-15 | | 最終更新日 | 2019-12-11 | | 実験手法 | X-RAY DIFFRACTION (2.637 Å) | | 主引用文献 | Potent and broad HIV-neutralizing antibodies in memory B cells and plasma.
Sci Immunol, 2, 2017
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5U3N
 | | Crystal Structure of DH511.12P Fab in Complex with HIV-1 gp41 MPER Peptide | | 分子名称: | DH511.12P Fab Heavy Chain, DH511.12P Fab Light Chain, gp41 MPER peptide | | 著者 | Ofek, G, Wu, L, Lougheed, C.S, Williams, L.D, Nicely, N.I, Haynes, B.F. | | 登録日 | 2016-12-02 | | 公開日 | 2017-02-15 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Potent and broad HIV-neutralizing antibodies in memory B cells and plasma.
Sci Immunol, 2, 2017
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5U3M
 | | Crystal Structure of DH511.11P Fab in Complex with HIV-1 gp41 MPER Peptide | | 分子名称: | DH511.11P Fab Heavy Chain, DH511.11P Fab Light Chain, gp41 MPER peptide | | 著者 | Ofek, G, Wu, L, Lougheed, C.S, Williams, L.D, Nicely, N.I, Haynes, B.F. | | 登録日 | 2016-12-02 | | 公開日 | 2017-02-15 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.418 Å) | | 主引用文献 | Potent and broad HIV-neutralizing antibodies in memory B cells and plasma.
Sci Immunol, 2, 2017
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4X6M
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4X6N
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4X6O
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4X6P
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8DCY
 | | CCHFV GP38 Hoti/Kosovo bound with 13G8 Fab | | 分子名称: | 13G8 Heavy Chain, 13G8 Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Durie, I.A, Bergeron, E, Pegan, S.D, McGuire, J. | | 登録日 | 2022-06-17 | | 公開日 | 2022-12-07 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (3.62 Å) | | 主引用文献 | Structural characterization of protective non-neutralizing antibodies targeting Crimean-Congo hemorrhagic fever virus.
Nat Commun, 13, 2022
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4W68
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5MW6
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5MWD
 | | Crystal structure of the BCL6 BTB-domain with compound 2 | | 分子名称: | 5-[[5-chloranyl-2-(3,5-dimethylpyrazol-1-yl)pyrimidin-4-yl]amino]-1,3-dihydroindol-2-one, B-cell lymphoma 6 protein | | 著者 | Bader, G, Flotzinger, G, Weiss-Puxbaum, A, Zoephel, A. | | 登録日 | 2017-01-18 | | 公開日 | 2017-10-04 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Chemically Induced Degradation of the Oncogenic Transcription Factor BCL6.
Cell Rep, 20, 2017
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5MQG
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4UTP
 | | Crystal structure of pneumococcal surface antigen PsaA in the Cd- bound, closed state | | 分子名称: | CADMIUM ION, MANGANESE ABC TRANSPORTER SUBSTRATE-BINDING LIPOPROTEIN | | 著者 | Luo, Z, Counago, R.M, Maher, M, Kobe, B. | | 登録日 | 2014-07-22 | | 公開日 | 2014-08-13 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Dysregulation of transition metal ion homeostasis is the molecular basis for cadmium toxicity in Streptococcus pneumoniae.
Nat Commun, 6, 2015
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4UTO
 | | Crystal structure of pneumococcal surface antigen PsaA D280N in the Cd-bound, open state | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CADMIUM ION, MANGANESE ABC TRANSPORTER SUBSTRATE-BINDING LIPOPROTEIN | | 著者 | Luo, Z, Counago, R.M, Maher, M, Kobe, B. | | 登録日 | 2014-07-22 | | 公開日 | 2015-03-11 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Dysregulation of transition metal ion homeostasis is the molecular basis for cadmium toxicity in Streptococcus pneumoniae.
Nat Commun, 6, 2015
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5MPZ
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