8AVZ
Crystal structure of PksD, the trans-acting acyl hydrolase domain from the bacillaene trans-AT PKS (SeMet derivative)
Summary for 8AVZ
| Entry DOI | 10.2210/pdb8avz/pdb |
| Related | 8AW0 |
| Descriptor | Polyketide biosynthesis acyltransferase homolog PksD, ZINC ION (3 entities in total) |
| Functional Keywords | alpha/beta-hydrolase, acyltransferase, polyketide synthase, biosynthesis, hydrolase |
| Biological source | Bacillus subtilis subsp. subtilis str. 168 |
| Total number of polymer chains | 4 |
| Total formula weight | 150927.61 |
| Authors | Fage, C.D.,Challis, G.L.,Lewandowski, J.,Jenner, M. (deposition date: 2022-08-28, release date: 2023-08-09, Last modification date: 2025-02-05) |
| Primary citation | Fage, C.D.,Passmore, M.,Tatman, B.P.,Smith, H.G.,Jian, X.,Dissanayake, U.C.,Foran, M.E.,Cisneros, G.A.,Challis, G.L.,Lewandowski, J.R.,Jenner, M. Molecular Basis for Short-Chain Thioester Hydrolysis by Acyl Hydrolases in trans-Acyltransferase Polyketide Synthases Jacs Au, 2025 Cited by DOI: 10.1021/jacsau.4c00837PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.96 Å) |
Structure validation
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