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5ZLU
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BU of 5zlu by Molmil
Ribosome Structure bound to ABC-F protein.
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Su, W.X, Kumar, V, Ero, R, Andrew, S.W.W, Jian, S, Yong-Gui, G.
登録日2018-03-29
公開日2018-08-01
最終更新日2019-12-04
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Ribosome protection by antibiotic resistance ATP-binding cassette protein.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
8J6R
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BU of 8j6r by Molmil
Cryo-EM structure of the MK-6892-bound human HCAR2-Gi1 complex
分子名称: 2-[[2,2-dimethyl-3-[3-(5-oxidanylpyridin-2-yl)-1,2,4-oxadiazol-5-yl]propanoyl]amino]cyclohexene-1-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Mao, C, Gao, M, Zang, S, Zhu, Y, Ma, X, Zhang, Y.
登録日2023-04-26
公開日2023-12-06
実験手法ELECTRON MICROSCOPY (2.76 Å)
主引用文献Orthosteric and allosteric modulation of human HCAR2 signaling complex.
Nat Commun, 14, 2023
8J6P
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BU of 8j6p by Molmil
Cryo-EM structure of the MK-6892-bound human HCAR2-Gi1 complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 7-methyl-N-[(2R)-1-phenoxypropan-2-yl]-3-(4-propan-2-ylphenyl)pyrazolo[1,5-a]pyrimidine-6-carboxamide, CHOLESTEROL, ...
著者Mao, C, Gao, M, Zang, S, Zhu, Y, Ma, X, Zhang, Y.
登録日2023-04-26
公開日2023-12-06
実験手法ELECTRON MICROSCOPY (2.55 Å)
主引用文献Orthosteric and allosteric modulation of human HCAR2 signaling complex.
Nat Commun, 14, 2023
8J6Q
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BU of 8j6q by Molmil
Cryo-EM structure of the 3-HB and compound 9n-bound human HCAR2-Gi1 complex
分子名称: (3R)-3-hydroxybutanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 7-methyl-N-[(2R)-1-phenoxypropan-2-yl]-3-(4-propan-2-ylphenyl)pyrazolo[1,5-a]pyrimidine-6-carboxamide, ...
著者Mao, C, Gao, M, Zang, S, Zhu, Y, Ma, X, Zhang, Y.
登録日2023-04-26
公開日2023-12-06
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Orthosteric and allosteric modulation of human HCAR2 signaling complex.
Nat Commun, 14, 2023
7WKX
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BU of 7wkx by Molmil
IL-17A in complex with the humanized antibody HB0017
分子名称: ACETIC ACID, Heavy chain of HB0017 Fab, Interleukin-17A, ...
著者Xu, J, Zhu, X, He, Y.
登録日2022-01-12
公開日2022-03-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献Structural and functional insights into a novel pre-clinical-stage antibody targeting IL-17A for treatment of autoimmune diseases.
Int.J.Biol.Macromol., 202, 2022
7CHV
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BU of 7chv by Molmil
Metallo-Beta-Lactamase VIM-2 in complex with 1-benzyl-1H-imidazole-2-carboxylic acid
分子名称: 1-(phenylmethyl)imidazole-2-carboxylic acid, Beta-lactamase class B VIM-2, FORMIC ACID, ...
著者Yan, Y.-H, Li, G.-B.
登録日2020-07-06
公開日2021-07-14
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.174 Å)
主引用文献AncPhore: A versatile tool for anchor pharmacophore steered drug discovery with applications in discovery of new inhibitors targeting metallo-beta-lactamases and indoleamine/tryptophan 2,3-dioxygenases.
Acta Pharm Sin B, 11, 2021
7CJS
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BU of 7cjs by Molmil
structure of aquaporin
分子名称: Aquaporin NIP2-1, CHOLESTEROL HEMISUCCINATE, SODIUM ION, ...
著者Saitoh, Y, Ma, J.F, Suga, M.
登録日2020-07-13
公開日2021-11-03
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis for high selectivity of a rice silicon channel Lsi1.
Nat Commun, 12, 2021
7F73
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BU of 7f73 by Molmil
Cryo-EM structure of human TMEM120B
分子名称: MCherry fluorescent protein,Transmembrane protein 120B
著者Ke, M, Wu, J, Yan, Z.
登録日2021-06-27
公開日2021-09-01
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Cryo-EM structures of human TMEM120A and TMEM120B.
Cell Discov, 7, 2021
7ESA
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BU of 7esa by Molmil
the complex structure of flavin transferase FmnB complexed with FAD
分子名称: FAD:protein FMN transferase, FLAVIN-ADENINE DINUCLEOTIDE, MAGNESIUM ION
著者Zheng, Y.H, Cheng, W.
登録日2021-05-09
公開日2021-11-03
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural insights into the catalytic and inhibitory mechanisms of the flavin transferase FmnB in Listeria monocytogenes.
MedComm (2020), 3, 2022
7F39
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BU of 7f39 by Molmil
The structure of flavin transferase FmnB
分子名称: FAD:protein FMN transferase
著者Cheng, W, Zheng, Y.H.
登録日2021-06-15
公開日2021-11-03
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.888 Å)
主引用文献Structural insights into the catalytic and inhibitory mechanisms of the flavin transferase FmnB in Listeria monocytogenes.
MedComm (2020), 3, 2022
7ESC
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BU of 7esc by Molmil
FmnB complexed with AMP
分子名称: ADENOSINE MONOPHOSPHATE, FAD:protein FMN transferase, MAGNESIUM ION
著者Cheng, W, Zheng, Y.H.
登録日2021-05-10
公開日2021-11-03
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.201 Å)
主引用文献Structural insights into the catalytic and inhibitory mechanisms of the flavin transferase FmnB in Listeria monocytogenes.
MedComm (2020), 3, 2022
7F2U
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BU of 7f2u by Molmil
FmnB complexed with ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, FAD:protein FMN transferase, MAGNESIUM ION
著者Cheng, W, Zheng, Y.H.
登録日2021-06-14
公開日2021-11-03
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.984 Å)
主引用文献Structural insights into the catalytic and inhibitory mechanisms of the flavin transferase FmnB in Listeria monocytogenes.
MedComm (2020), 3, 2022
7ESB
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BU of 7esb by Molmil
FmnB complexed with ATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, FAD:protein FMN transferase, MAGNESIUM ION
著者Zheng, Y.H, Cheng, W.
登録日2021-05-09
公開日2021-11-03
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural insights into the catalytic and inhibitory mechanisms of the flavin transferase FmnB in Listeria monocytogenes.
MedComm (2020), 3, 2022
7FF9
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BU of 7ff9 by Molmil
Pseudomonas aeruginosa Virulence Factor Regulator with cAMP ligand and Cl(triethylphosphine)gold(I)
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, CHLORIDE ION, GOLD ION, ...
著者Chew, B.L.A, Luo, D.
登録日2021-07-23
公開日2022-07-27
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Inhibitory mechanism of gold analogues against Pseudomonas global virulence factor regulator Vfr
To Be Published
7FEW
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BU of 7few by Molmil
Pseudomonas aeruginosa Virulence Factor Regulator with cAMP ligand and auranofin gold analogues
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, SULFATE ION, cAMP-activated global transcriptional regulator Vfr
著者Chew, B.L.A, Luo, D.
登録日2021-07-22
公開日2022-07-27
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural basis for the inhibitory mechanism of auranofin and gold(I) analogues against Pseudomonas aeruginosa global virulence factor regulator Vfr.
Comput Struct Biotechnol J, 21, 2023
7FIA
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BU of 7fia by Molmil
Structure of AcrIF23
分子名称: AcrIF23
著者Ren, J, Yue, F.
登録日2021-07-30
公開日2022-07-27
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Structural and mechanistic insights into the inhibition of type I-F CRISPR-Cas system by anti-CRISPR protein AcrIF23.
J.Biol.Chem., 298, 2022
7FF0
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BU of 7ff0 by Molmil
Pseudomonas aeruginosa Virulence Factor Regulator with cAMP ligand and auranofin
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, GOLD ION, SULFATE ION, ...
著者Chew, B.L.A, Luo, D.
登録日2021-07-22
公開日2022-07-27
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis for the inhibitory mechanism of auranofin and gold(I) analogues against Pseudomonas aeruginosa global virulence factor regulator Vfr.
Comput Struct Biotechnol J, 21, 2023
7FF8
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BU of 7ff8 by Molmil
Pseudomonas aeruginosa Virulence Factor Regulator with cAMP ligand and Cl(triethylphosphine)gold(I)
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, CHLORIDE ION, GOLD ION, ...
著者Chew, B.L.A, Luo, D.
登録日2021-07-22
公開日2022-07-27
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Inhibitory mechanism of gold analogues against Pseudomonas global virulence factor regulator Vfr
To Be Published
7CXR
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BU of 7cxr by Molmil
Cryo-EM structure of human TMEM120A/TACAN
分子名称: MCherry fluorescent protein,Ion channel TACAN
著者Yan, Z, Wu, J, Ke, M.
登録日2020-09-02
公開日2021-09-01
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Cryo-EM structures of human TMEM120A and TMEM120B.
Cell Discov, 7, 2021
7F61
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BU of 7f61 by Molmil
Crystal structure of human histamine receptor H3R in complex with antagonist PF03654746
分子名称: CHOLESTEROL, Histamine H3 receptor, N-ethyl-3-fluoranyl-3-[3-fluoranyl-4-(pyrrolidin-1-ylmethyl)phenyl]cyclobutane-1-carboxamide, ...
著者Peng, X, Zhang, H.
登録日2021-06-23
公開日2022-10-26
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis for recognition of antihistamine drug by human histamine receptor.
Nat Commun, 13, 2022
7VZB
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BU of 7vzb by Molmil
Cryo-EM structure of C22:0-CoA bound human very long-chain fatty acid ABC transporter ABCD1
分子名称: CHOLESTEROL HEMISUCCINATE, Peroxisomal Membrane Protein related,ATP-binding cassette sub-family D member 1, S-[2-[3-[[(2R)-4-[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-3,3-dimethyl-2-oxidanyl-butanoyl]amino]propanoylamino]ethyl] docosanethioate
著者Chen, Z.P, Xu, D, Wang, L, Mao, Y.X, Yang, L, Cheng, M.T, Hou, W.T, Chen, Y.X, Zhou, C.Z.
登録日2021-11-15
公開日2022-05-18
最終更新日2022-06-22
実験手法ELECTRON MICROSCOPY (3.59 Å)
主引用文献Structural basis of substrate recognition and translocation by human very long-chain fatty acid transporter ABCD1.
Nat Commun, 13, 2022
7VWC
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BU of 7vwc by Molmil
Cryo-EM structure of human very long-chain fatty acid ABC transporter ABCD1
分子名称: Peroxisomal Membrane Protein related,ATP-binding cassette sub-family D member 1, [(2R)-3-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-2-oxidanyl-propyl] octadecanoate
著者Chen, Z.P, Xu, D, Wang, L, Mao, Y.X, Yang, L, Cheng, M.T, Hou, W.T, Chen, Y.X, Zhou, C.Z.
登録日2021-11-10
公開日2022-05-18
最終更新日2022-06-22
実験手法ELECTRON MICROSCOPY (3.53 Å)
主引用文献Structural basis of substrate recognition and translocation by human very long-chain fatty acid transporter ABCD1.
Nat Commun, 13, 2022
7VX8
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BU of 7vx8 by Molmil
Cryo-EM structure of ATP-bound human very long-chain fatty acid ABC transporter ABCD1
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Peroxisomal Membrane Protein related,ATP-binding cassette sub-family D member 1
著者Chen, Z.P, Xu, D, Wang, L, Mao, Y.X, Yang, L, Cheng, M.T, Hou, W.T, Chen, Y.X, Zhou, C.Z.
登録日2021-11-12
公開日2022-05-18
最終更新日2022-06-22
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structural basis of substrate recognition and translocation by human very long-chain fatty acid transporter ABCD1.
Nat Commun, 13, 2022
7XR5
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BU of 7xr5 by Molmil
Crystal structure of imine reductase with NAPDH from Streptomyces albidoflavus
分子名称: 3,6,9,12,15,18,21,24,27,30,33,36,39,42,45,48,51,54,57-nonadecaoxanonapentacontane-1,59-diol, 6-phosphogluconate dehydrogenase NAD-binding, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Zhang, J, Chen, R.C, Gao, S.S.
登録日2022-05-09
公開日2022-10-19
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Actinomycetes-derived imine reductases with a preference towards bulky amine substrates.
Commun Chem, 5, 2022
7XE8
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BU of 7xe8 by Molmil
Crystal structure of imine reductase from Streptomyces albidoflavus
分子名称: 6-phosphogluconate dehydrogenase NAD-binding
著者Zhang, J, Chen, R.C, Gao, S.S.
登録日2022-03-30
公開日2022-10-12
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献Actinomycetes-derived imine reductases with a preference towards bulky amine substrates
Commun Chem, 5, 2022

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