7ER1
 
 | |
7ER0
 | |
5SY1
 | | Structure of the STRA6 receptor for retinol uptake in complex with calmodulin | | 分子名称: | CALCIUM ION, CHOLESTEROL, Calmodulin, ... | | 著者 | Clarke, O.B, Chen, Y, Mancia, F. | | 登録日 | 2016-08-10 | | 公開日 | 2016-08-24 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Structure of the STRA6 receptor for retinol uptake.
Science, 353, 2016
|
|
5VBD
 | | Crystal structure of a putative UBL domain of USP9X | | 分子名称: | UNKNOWN ATOM OR ION, USP9X | | 著者 | Dong, A, Chern, Y, Hou, F, Li, Y, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Tong, Y, Structural Genomics Consortium (SGC) | | 登録日 | 2017-03-29 | | 公開日 | 2017-04-26 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Crystal structure of a putative UBL domain of USP9X
to be published
|
|
4V8U
 | | Crystal Structure of 70S Ribosome with Both Cognate tRNAs in the E and P Sites Representing an Authentic Elongation Complex. | | 分子名称: | 16S RIBOSOMAL RNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ... | | 著者 | Gao, Y.G, Feng, S, Chen, Y. | | 登録日 | 2012-08-28 | | 公開日 | 2014-07-09 | | 最終更新日 | 2019-10-30 | | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | | 主引用文献 | Crystal structure of 70S ribosome with both cognate tRNAs in the E and P sites representing an authentic elongation complex.
PLoS ONE, 8, 2013
|
|
5VKQ
 | | Structure of a mechanotransduction ion channel Drosophila NOMPC in nanodisc | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSHOCHOLINE, No mechanoreceptor potential C isoform L | | 著者 | Jin, P, Bulkley, D, Guo, Y, Zhang, W, Guo, Z, Huynh, W, Wu, S, Meltzer, S, Chen, T, Jan, L.Y, Jan, Y.-N, Cheng, Y. | | 登録日 | 2017-04-22 | | 公開日 | 2017-06-28 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.55 Å) | | 主引用文献 | Electron cryo-microscopy structure of the mechanotransduction channel NOMPC.
Nature, 547, 2017
|
|
4OI6
 | | Crystal structure analysis of nickel-bound form SCO4226 from Streptomyces coelicolor A3(2) | | 分子名称: | CITRIC ACID, NICKEL (II) ION, Nickel responsive protein | | 著者 | Lu, M, Jiang, Y.L, Wang, S, Cheng, W, Zhang, R.G, Virolle, M.J, Chen, Y, Zhou, C.Z. | | 登録日 | 2014-01-18 | | 公開日 | 2014-09-10 | | 最終更新日 | 2018-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | | 主引用文献 | Streptomyces coelicolor SCO4226 Is a Nickel Binding Protein.
Plos One, 9, 2014
|
|
5K5S
 | | Crystal structure of the active form of human calcium-sensing receptor extracellular domain | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Extracellular calcium-sensing receptor, ... | | 著者 | Geng, Y, Mosyak, L, Kurinov, I, Zuo, H, Sturchler, E, Cheng, T.C, Subramanyam, P, Brown, A.P, Brennan, S.C, Mun, H.-C, Bush, M, Chen, Y, Nguyen, T, Cao, B, Chang, D, Quick, M, Conigrave, A, Colecraft, H.M, McDonald, P, Fan, Q.R. | | 登録日 | 2016-05-23 | | 公開日 | 2016-08-03 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural mechanism of ligand activation in human calcium-sensing receptor.
Elife, 5, 2016
|
|
7RSJ
 | | Structure of the VPS34 kinase domain with compound 14 | | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, N-{4-[(7R,8R)-4-oxo-7-(propan-2-yl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazin-2-yl]pyridin-2-yl}cyclopropanecarboxamide, ... | | 著者 | Hu, D.X, Patel, S, Chen, H, Wang, S, Staben, S, Dimitrova, Y.N, Wallweber, H.A, Lee, J.Y, Chan, G.K.Y, Sneeringer, C.J, Prangley, M.S, Moffat, J.G, Wu, C, Schutt, L.K, Salphati, L, Pang, J, McNamara, E, Huang, H, Chen, Y, Wang, Y, Zhao, W, Lim, J, Murthy, A, Siu, M. | | 登録日 | 2021-08-11 | | 公開日 | 2021-11-24 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.881 Å) | | 主引用文献 | Structure-Based Design of Potent, Selective, and Orally Bioavailable VPS34 Kinase Inhibitors.
J.Med.Chem., 65, 2022
|
|
7RSP
 | | Structure of the VPS34 kinase domain with compound 14 | | 分子名称: | (7R,8R)-2-[(3R)-3-methylmorpholin-4-yl]-7-(propan-2-yl)-6,7-dihydropyrazolo[1,5-a]pyrazin-4(5H)-one, GLYCEROL, Phosphatidylinositol 3-kinase catalytic subunit type 3 | | 著者 | Hu, D.X, Patel, S, Chen, H, Wang, S, Staben, S, Dimitrova, Y.N, Wallweber, H.A, Lee, J.Y, Chan, G.K.Y, Sneeringer, C.J, Prangley, M.S, Moffat, J.G, Wu, C, Schutt, L.K, Salphati, L, Pang, J, McNamara, E, Huang, H, Chen, Y, Wang, Y, Zhao, W, Lim, J, Murthy, A, Siu, M. | | 登録日 | 2021-08-11 | | 公開日 | 2021-11-24 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | | 主引用文献 | Structure-Based Design of Potent, Selective, and Orally Bioavailable VPS34 Kinase Inhibitors.
J.Med.Chem., 65, 2022
|
|
7RSV
 | | Structure of the VPS34 kinase domain with compound 5 | | 分子名称: | (5aS,8aR,9S)-2-[(3R)-3-methylmorpholin-4-yl]-5,5a,6,7,8,8a-hexahydro-4H-cyclopenta[e]pyrazolo[1,5-a]pyrazin-4-one, GLYCEROL, Phosphatidylinositol 3-kinase catalytic subunit type 3, ... | | 著者 | Hu, D.X, Patel, S, Chen, H, Wang, S, Staben, S, Dimitrova, Y.N, Wallweber, H.A, Lee, J.Y, Chan, G.K.Y, Sneeringer, C.J, Prangley, M.S, Moffat, J.G, Wu, C, Schutt, L.K, Salphati, L, Pang, J, McNamara, E, Huang, H, Chen, Y, Wang, Y, Zhao, W, Lim, J, Murthy, A, Siu, M. | | 登録日 | 2021-08-11 | | 公開日 | 2021-11-24 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | Structure-Based Design of Potent, Selective, and Orally Bioavailable VPS34 Kinase Inhibitors.
J.Med.Chem., 65, 2022
|
|
4F11
 | | Crystal structure of the extracellular domain of human GABA(B) receptor GBR2 | | 分子名称: | Gamma-aminobutyric acid type B receptor subunit 2 | | 著者 | Geng, Y, Xiong, D, Mosyak, L, Malito, D.L, Kniazeff, J, Chen, Y, Burmakina, S, Quick, M, Bush, M, Javitch, J.A, Pin, J.-P, Fan, Q.R. | | 登録日 | 2012-05-05 | | 公開日 | 2012-06-06 | | 最終更新日 | 2012-08-15 | | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | | 主引用文献 | Structure and functional interaction of the extracellular domain of human GABA(B) receptor GBR2.
Nat.Neurosci., 15, 2012
|
|
2FS1
 | | solution structure of PSD-1 | | 分子名称: | PSD-1 | | 著者 | He, Y, Rozak, D.A, Sari, N, Chen, Y, Bryan, P, Orban, J. | | 登録日 | 2006-01-20 | | 公開日 | 2006-12-05 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure, dynamics, and stability variation in bacterial albumin binding modules: implications for species specificity.
Biochemistry, 45, 2006
|
|
4F3L
 | | Crystal Structure of the Heterodimeric CLOCK:BMAL1 Transcriptional Activator Complex | | 分子名称: | BMAL1b, Circadian locomoter output cycles protein kaput | | 著者 | Huang, N, Chelliah, Y, Shan, Y, Taylor, C, Yoo, S, Partch, C, Green, C.B, Zhang, H, Takahashi, J. | | 登録日 | 2012-05-09 | | 公開日 | 2012-06-06 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.268 Å) | | 主引用文献 | Crystal structure of the heterodimeric CLOCK:BMAL1 transcriptional activator complex.
Science, 337, 2012
|
|
6QOZ
 | | CryoEM reconstruction of Cowpea Mosaic Virus (CPMV) bound to an Affimer reagent | | 分子名称: | Affimer binding protein, Cowpea mosaic virus large subunit, RNA2 polyprotein | | 著者 | Hesketh, E.L, Tiede, C, Adamson, H, Adams, T.L, Byrne, M.J, Meshcheriakova, Y, Lomonossoff, G.P, Kruse, I, McPherson, M.J, Tomlinson, D.C, Ranson, N.A. | | 登録日 | 2019-02-13 | | 公開日 | 2019-12-18 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Affimer reagents as tools in diagnosing plant virus diseases.
Sci Rep, 9, 2019
|
|
6ZGP
 | | Crystal structure of the quaternary ammonium Rieske monooxygenase CntA in complex with inhibitor MMV12 (MMV020670) | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Carnitine monooxygenase oxygenase subunit, FE (III) ION, ... | | 著者 | Quareshy, M, Shanmugam, M, Bugg, T.D.H, Cameron, A, Chen, Y. | | 登録日 | 2020-06-19 | | 公開日 | 2020-11-18 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | Structural basis of carnitine monooxygenase CntA substrate specificity, inhibition, and intersubunit electron transfer.
J.Biol.Chem., 296, 2020
|
|
7RN0
 | |
7RN1
 | |
7RPK
 | | Cryo-EM structure of murine Dispatched in complex with Sonic hedgehog | | 分子名称: | (2S)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(hexanoyloxy)propyl hexanoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Asarnow, D, Wang, Q, Ding, K, Cheng, Y, Beachy, P.A. | | 登録日 | 2021-08-03 | | 公開日 | 2021-10-27 | | 最終更新日 | 2023-12-13 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Dispatched uses Na + flux to power release of lipid-modified Hedgehog.
Nature, 599, 2021
|
|
7RPJ
 | | Cryo-EM structure of murine Dispatched NNN mutant | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, Protein dispatched homolog 1 | | 著者 | Asarnow, D, Wang, Q, Ding, K, Cheng, Y, Beachy, P.A. | | 登録日 | 2021-08-03 | | 公開日 | 2021-10-27 | | 最終更新日 | 2021-11-24 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Dispatched uses Na + flux to power release of lipid-modified Hedgehog.
Nature, 599, 2021
|
|
7RPH
 | | Cryo-EM structure of murine Dispatched 'R' conformation | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, Lauryl Maltose Neopentyl Glycol, ... | | 著者 | Asarnow, D, Wang, Q, Ding, K, Cheng, Y, Beachy, P.A. | | 登録日 | 2021-08-03 | | 公開日 | 2021-10-27 | | 最終更新日 | 2023-12-13 | | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | | 主引用文献 | Dispatched uses Na + flux to power release of lipid-modified Hedgehog.
Nature, 599, 2021
|
|
7RPI
 | | Cryo-EM structure of murine Dispatched 'T' conformation | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, Lauryl Maltose Neopentyl Glycol, ... | | 著者 | Asarnow, D, Wang, Q, Ding, K, Cheng, Y, Beachy, P.A. | | 登録日 | 2021-08-03 | | 公開日 | 2021-10-27 | | 最終更新日 | 2023-12-13 | | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | | 主引用文献 | Dispatched uses Na + flux to power release of lipid-modified Hedgehog.
Nature, 599, 2021
|
|
3V36
 | | Aldose reductase complexed with glceraldehyde | | 分子名称: | Aldose reductase, D-Glyceraldehyde, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | 著者 | Zheng, X, Zhang, L, Chen, Y, Luo, H, Hu, X. | | 登録日 | 2011-12-13 | | 公開日 | 2012-08-29 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Partial inhibition of aldose reductase by nitazoxanide and its molecular basis.
Chemmedchem, 7, 2012
|
|
5VLE
 | |
3HIX
 | | Crystal Structure of the Rhodanese_3 like domain from Anabaena sp Alr3790 protein. Northeast Structural Genomics Consortium Target NsR437i | | 分子名称: | Alr3790 protein, MANGANESE (II) ION | | 著者 | Vorobiev, S, Chen, Y, Forouhar, F, Maglaqui, M, Ciccosanti, C, Mao, L, Xiao, R, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2009-05-20 | | 公開日 | 2009-05-26 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | | 主引用文献 | Crystal Structure of the Rhodanese_3 like domain from Anabaena sp Alr3790 protein.
To be Published
|
|
