5YDR
| Structure of DNMT1 RFTS domain in complex with ubiquitin | 分子名称: | DNA (cytosine-5)-methyltransferase 1, PHOSPHATE ION, Polyubiquitin-B, ... | 著者 | Qian, C. | 登録日 | 2017-09-14 | 公開日 | 2018-02-21 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.003 Å) | 主引用文献 | Structural and mechanistic insights into UHRF1-mediated DNMT1 activation in the maintenance DNA methylation. Nucleic Acids Res., 46, 2018
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8GTN
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8GTK
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8GTJ
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7E3O
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6J56
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7Y3B
| Crystal structure of TRIM7 bound to GN1 | 分子名称: | E3 ubiquitin-protein ligase TRIM7,TRIM7-GN1 | 著者 | Dong, C, Yan, X. | 登録日 | 2022-06-10 | 公開日 | 2022-08-03 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | 主引用文献 | C-terminal glutamine acts as a C-degron targeted by E3 ubiquitin ligase TRIM7. Proc.Natl.Acad.Sci.USA, 119, 2022
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7Y3C
| Crystal structure of TRIM7 bound to RACO-1 | 分子名称: | E3 ubiquitin-protein ligase TRIM7,E3 ubiquitin-protein ligase TRIM7,TRIM7-RACO-1 | 著者 | Dong, C, Yan, X. | 登録日 | 2022-06-10 | 公開日 | 2022-08-03 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | 主引用文献 | C-terminal glutamine acts as a C-degron targeted by E3 ubiquitin ligase TRIM7. Proc.Natl.Acad.Sci.USA, 119, 2022
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7Y3A
| Crystal structure of TRIM7 bound to 2C | 分子名称: | E3 ubiquitin-protein ligase TRIM7,E3 ubiquitin-protein ligase TRIM7,E3 ubiquitin-protein ligase TRIM7,TRIM7-2C | 著者 | Dong, C, Yan, X. | 登録日 | 2022-06-10 | 公開日 | 2022-08-03 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | C-terminal glutamine acts as a C-degron targeted by E3 ubiquitin ligase TRIM7. Proc.Natl.Acad.Sci.USA, 119, 2022
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7EP0
| Crystal structure of ZYG11B bound to GSTE degron | 分子名称: | Protein zyg-11 homolog B, sodium 3,3'-(1E,1'E)-biphenyl-4,4'-diylbis(diazene-2,1-diyl)bis(4-aminonaphthalene-1-sulfonate) | 著者 | Yan, X, Li, Y. | 登録日 | 2021-04-26 | 公開日 | 2021-07-14 | 最終更新日 | 2021-09-01 | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | 主引用文献 | Molecular basis for recognition of Gly/N-degrons by CRL2 ZYG11B and CRL2 ZER1 . Mol.Cell, 81, 2021
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7EP3
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7EP2
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7EP5
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7EP1
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7EP4
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5GIY
| HSA-Palmitic acid-[RuCl5(ind)]2- | 分子名称: | PALMITIC ACID, Serum albumin, pentakis(chloranyl)-(1~{H}-indazol-2-ium-2-yl)ruthenium(1-) | 著者 | Yang, F, Wang, T. | 登録日 | 2016-06-25 | 公開日 | 2017-07-19 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.543 Å) | 主引用文献 | Structure of HSA-Palmitic acid-[RuCl5(ind)]2- To Be Published
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7EAA
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7EA7
| crystal structure of NAP1 LIR in complex with GABARAP | 分子名称: | Gamma-aminobutyric acid receptor-associated protein, NAP1_LIR motif | 著者 | Fu, T, Pan, L. | 登録日 | 2021-03-06 | 公開日 | 2021-12-22 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.69 Å) | 主引用文献 | Structural and biochemical advances on the recruitment of the autophagy-initiating ULK and TBK1 complexes by autophagy receptor NDP52. Sci Adv, 7, 2021
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7EA2
| crystal structure of NAP1 FIR in complex with RB1CC1 Claw domain | 分子名称: | 5-azacytidine-induced protein 2,RB1-inducible coiled-coil protein 1, CITRATE ANION, DI(HYDROXYETHYL)ETHER, ... | 著者 | Fu, T, Pan, L. | 登録日 | 2021-03-06 | 公開日 | 2021-12-22 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | 主引用文献 | Structural and biochemical advances on the recruitment of the autophagy-initiating ULK and TBK1 complexes by autophagy receptor NDP52. Sci Adv, 7, 2021
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7YFK
| The structure of human pregnane X receptor in complex with an SRC-1 coactivator peptide and a limonoid compound, nomilin | 分子名称: | Nomilin, Nuclear receptor subfamily 1 group I member 2,Nuclear receptor coactivator 1 | 著者 | Xia, Y, Yao, D, Huang, C, Cao, Y. | 登録日 | 2022-07-08 | 公開日 | 2023-06-14 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Pregnane X receptor agonist nomilin extends lifespan and healthspan in preclinical models through detoxification functions. Nat Commun, 14, 2023
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6JPE
| Crystal structure of FGFR4 kinase domain with irreversible inhibitor 1 | 分子名称: | Fibroblast growth factor receptor 4, N-[2-[[6-[2-[[2,6-bis(chloranyl)-3,5-dimethoxy-phenyl]amino]pyridin-3-yl]pyrimidin-4-yl]amino]-3-methyl-phenyl]prop-2-enamide, SULFATE ION | 著者 | Chen, X, Dai, S, Zhou, Z, Chen, Y. | 登録日 | 2019-03-26 | 公開日 | 2020-05-06 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.601 Å) | 主引用文献 | Development of a Potent and Specific FGFR4 Inhibitor for the Treatment of Hepatocellular Carcinoma. J.Med.Chem., 63, 2020
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