1TXO
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![BU of 1txo by Molmil](/molmil-images/mine/1txo) | Crystal structure of the Mycobacterium tuberculosis serine/threonine phosphatase PstP/Ppp at 1.95 A. | 分子名称: | MANGANESE (II) ION, Putative Bacterial Enzyme | 著者 | Pullen, K.E, Ng, H.L, Sung, P.Y, Good, M.C, Smith, S.M, Alber, T, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2004-07-05 | 公開日 | 2004-11-23 | 最終更新日 | 2017-10-11 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | An Alternate Conformation and a Third Metal in PstP/Ppp, the M. tuberculosis PP2C-Family Ser/Thr Protein Phosphatase. Structure, 12, 2004
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3FLG
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![BU of 3flg by Molmil](/molmil-images/mine/3flg) | The PWWP domain of Human DNA (cytosine-5-)-methyltransferase 3 beta | 分子名称: | DNA (cytosine-5)-methyltransferase 3B | 著者 | Amaya, M.F, Zeng, H, MacKenzie, F, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Botchkarev, A, Min, J, Wu, H, Structural Genomics Consortium (SGC) | 登録日 | 2008-12-18 | 公開日 | 2009-03-31 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal Structure of the PWWP domain of Human DNA (cytosine-5-)-methyltransferase 3 beta To be Published
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1RJN
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![BU of 1rjn by Molmil](/molmil-images/mine/1rjn) | The Crystal Structure of MenB (Rv0548c) from Mycobacterium tuberculosis in Complex with the CoA Portion of Naphthoyl CoA | 分子名称: | 3-[4-(2-HYDROXYETHYL)PIPERAZIN-1-YL]PROPANE-1-SULFONIC ACID, COENZYME A, menB | 著者 | Johnston, J.M, Arcus, V.L, Baker, E.N, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2003-11-19 | 公開日 | 2004-11-30 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure of naphthoate synthase (MenB) from Mycobacterium tuberculosis in both native and product-bound forms. Acta Crystallogr.,Sect.D, 61, 2005
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1RJM
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![BU of 1rjm by Molmil](/molmil-images/mine/1rjm) | Crystal Structure of MenB (Rv0548c) from Mycobacterium tuberculosis | 分子名称: | 3-[4-(2-HYDROXYETHYL)PIPERAZIN-1-YL]PROPANE-1-SULFONIC ACID, MenB | 著者 | Johnston, J.M, Arcus, V.L, Baker, E.N, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2003-11-19 | 公開日 | 2004-11-30 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Structure of naphthoate synthase (MenB) from Mycobacterium tuberculosis in both native and product-bound forms. Acta Crystallogr.,Sect.D, 61, 2005
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3FVY
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![BU of 3fvy by Molmil](/molmil-images/mine/3fvy) | Crystal structure of human Dipeptidyl Peptidase III | 分子名称: | CHLORIDE ION, Dipeptidyl-peptidase 3, MAGNESIUM ION, ... | 著者 | Dong, A, Dobrovetsky, E, Seitova, A, Duncan, B, Crombet, L, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bochkarev, A, Cossar, D, Structural Genomics Consortium (SGC) | 登録日 | 2009-01-16 | 公開日 | 2009-02-03 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Entropy-driven binding of opioid peptides induces a large domain motion in human dipeptidyl peptidase III. Proc.Natl.Acad.Sci.USA, 109, 2012
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2O0L
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![BU of 2o0l by Molmil](/molmil-images/mine/2o0l) | Human spermidine synthase | 分子名称: | 5'-[(S)-(3-AMINOPROPYL)(METHYL)-LAMBDA~4~-SULFANYL]-5'-DEOXYADENOSINE, Spermidine synthase | 著者 | Min, J, Wu, H, Zeng, H, Loppnau, P, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC) | 登録日 | 2006-11-27 | 公開日 | 2006-12-12 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Structure and mechanism of spermidine synthases. Biochemistry, 46, 2007
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1YW4
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![BU of 1yw4 by Molmil](/molmil-images/mine/1yw4) | Crystal Structure of the Succinylglutamate Desuccinylase from Chromobacterium violaceum, Northeast Structural Genomics Target CvR22. | 分子名称: | Succinylglutamate desuccinylase, ZINC ION | 著者 | Forouhar, F, Abashidze, M, Conover, K, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2005-02-17 | 公開日 | 2005-03-01 | 最終更新日 | 2017-10-11 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structure of the Succinylglutamate Desuccinylase from Chromobacterium violaceum, Northeast Structural Genomics Target CvR22. To be Published
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2P8U
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![BU of 2p8u by Molmil](/molmil-images/mine/2p8u) | Crystal structure of human 3-hydroxy-3-methylglutaryl CoA synthase I | 分子名称: | COENZYME A, GLYCEROL, Hydroxymethylglutaryl-CoA synthase, ... | 著者 | Turnbull, A, Shafqat, N, Salah, E, Niesen, F.H, Burgess, N, Bunkoczi, G, Debreczeni, J, Pike, A.C.W, Umeano, C, Gorrec, F, von Delft, F, Weigelt, J, Arrowsmith, C.H, Sundstrom, M, Edwards, A, Oppermann, U, Structural Genomics Consortium (SGC) | 登録日 | 2007-03-23 | 公開日 | 2007-04-03 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structures of human HMG-CoA synthase isoforms provide insights into inherited ketogenesis disorders and inhibitor design. J.Mol.Biol., 398, 2010
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2O07
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![BU of 2o07 by Molmil](/molmil-images/mine/2o07) | Human spermidine synthase | 分子名称: | 5'-DEOXY-5'-METHYLTHIOADENOSINE, SPERMIDINE, Spermidine synthase | 著者 | Min, J, Wu, H, Zeng, H, Loppnau, P, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC) | 登録日 | 2006-11-27 | 公開日 | 2006-12-12 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | Structure and mechanism of spermidine synthases. Biochemistry, 46, 2007
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2O06
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![BU of 2o06 by Molmil](/molmil-images/mine/2o06) | Human spermidine synthase | 分子名称: | 1,4-DIAMINOBUTANE, 5'-DEOXY-5'-METHYLTHIOADENOSINE, MAGNESIUM ION, ... | 著者 | Min, J, Wu, H, Zeng, H, Loppnau, P, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC) | 登録日 | 2006-11-27 | 公開日 | 2006-12-12 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure and mechanism of spermidine synthases. Biochemistry, 46, 2007
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2O8J
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![BU of 2o8j by Molmil](/molmil-images/mine/2o8j) | Human euchromatic histone methyltransferase 2 | 分子名称: | Histone-lysine N-methyltransferase, H3 lysine-9 specific 3, S-ADENOSYL-L-HOMOCYSTEINE, ... | 著者 | Min, J, Wu, H, Antoshenko, T, Loppnau, P, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC) | 登録日 | 2006-12-12 | 公開日 | 2007-01-16 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural biology of human H3K9 methyltransferases Plos One, 5, 2010
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1TFU
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1XM3
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![BU of 1xm3 by Molmil](/molmil-images/mine/1xm3) | Crystal structure of Northeast Structural Genomics Target SR156 | 分子名称: | Thiazole biosynthesis protein thiG | 著者 | Kuzin, A, Abashidze, M, Vorobiev, S, Forouhar, F, Acton, T, Ma, L, Xiao, R, Montelione, G, Tong, L, Hunt, J, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2004-10-01 | 公開日 | 2004-10-19 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structure of Northeast Structural Genomics Target SR156 To be Published
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4JII
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![BU of 4jii by Molmil](/molmil-images/mine/4jii) | Crystal Structure Of AKR1B10 Complexed With NADP+ And Zopolrestat | 分子名称: | 3,4-DIHYDRO-4-OXO-3-((5-TRIFLUOROMETHYL-2-BENZOTHIAZOLYL)METHYL)-1-PHTHALAZINE ACETIC ACID, Aldo-keto reductase family 1 member B10, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | 著者 | Zhang, L, Zheng, X, Zhang, H, Zhao, Y, Chen, K, Zhai, J, Hu, X, Structural Genomics Consortium (SGC) | 登録日 | 2013-03-06 | 公開日 | 2013-10-23 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Inhibitor selectivity between aldo-keto reductase superfamily members AKR1B10 and AKR1B1: Role of Trp112 (Trp111). Febs Lett., 587, 2013
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2O1O
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![BU of 2o1o by Molmil](/molmil-images/mine/2o1o) | Cryptosporidium parvum putative polyprenyl pyrophosphate synthase (cgd4_2550) in complex with risedronate. | 分子名称: | 1-HYDROXY-2-(3-PYRIDINYL)ETHYLIDENE BIS-PHOSPHONIC ACID, MAGNESIUM ION, Putative farnesyl pyrophosphate synthase | 著者 | Chruszcz, M, Artz, J.D, Dong, A, Dunford, J, Lew, J, Zhao, Y, Kozieradski, I, Kavanaugh, K.L, Oppermann, U, Sundstrom, M, Weigelt, J, Edwards, A.M, Arrowsmith, C.H, Bochkarev, A, Hui, R, Minor, W, Structural Genomics Consortium (SGC) | 登録日 | 2006-11-29 | 公開日 | 2006-12-12 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.42 Å) | 主引用文献 | Targeting a uniquely nonspecific prenyl synthase with bisphosphonates to combat cryptosporidiosis Chem.Biol., 15, 2008
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2VPI
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![BU of 2vpi by Molmil](/molmil-images/mine/2vpi) | Human GMP synthetase - glutaminase domain | 分子名称: | GMP SYNTHASE | 著者 | Welin, M, Tresaugues, L, Arrowsmith, C.H, Berglund, H, Busam, R.D, Collins, R, Dahlgren, L.G, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Herman, M.D, Johansson, I, Kallas, A, Karlberg, T, Kotenyova, T, Lehtio, L, Moche, M, Nilsson, M.E, Nyman, T, Persson, C, Sagemark, J, Svensson, L, Thorsell, A.G, Van Der Berg, S, Weigelt, J, Nordlund, P, Structural Genomics Consortium (SGC) | 登録日 | 2008-02-29 | 公開日 | 2008-03-11 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Human Gmp Synthetase - Glutaminase Domain To be Published
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2Q58
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![BU of 2q58 by Molmil](/molmil-images/mine/2q58) | Cryptosporidium parvum putative polyprenyl pyrophosphate synthase (cgd4_2550) in complex with zoledronate | 分子名称: | Farnesyl pyrophosphate synthase, MAGNESIUM ION, ZOLEDRONIC ACID | 著者 | Chruszcz, M, Artz, J, Zheng, H, Dong, A, Dunford, J, Lew, J, Zhao, Y, Kozieradski, I, Kavanaugh, K.L, Opperman, U, Sundstrom, M, Weigelt, J, Edwards, A, Arrowsmith, C, Bochkarev, A, Hui, R, Minor, W, Structural Genomics Consortium (SGC) | 登録日 | 2007-05-31 | 公開日 | 2007-06-12 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.37 Å) | 主引用文献 | Targeting a uniquely nonspecific prenyl synthase with bisphosphonates to combat cryptosporidiosis Chem.Biol., 15, 2008
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3G0H
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![BU of 3g0h by Molmil](/molmil-images/mine/3g0h) | Human dead-box RNA helicase DDX19, in complex with an ATP-analogue and RNA | 分子名称: | 5'-R(P*UP*UP*UP*UP*UP*UP*U)-3', ATP-dependent RNA helicase DDX19B, GLYCEROL, ... | 著者 | Karlberg, T, Lehtio, L, Collins, R, Arrowsmith, C.H, Berglund, H, Bountra, C, Dahlgren, L.G, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Kotenyova, T, Moche, M, Nilsson, M.E, Nordlund, P, Nyman, T, Persson, C, Sagemark, J, Schutz, P, Siponen, M.I, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Weigelt, J, Welin, M, Wisniewska, M, Schuler, H, Structural Genomics Consortium (SGC) | 登録日 | 2009-01-28 | 公開日 | 2009-02-17 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | The DEXD/H-box RNA Helicase DDX19 Is Regulated by an {alpha}-Helical Switch. J.Biol.Chem., 284, 2009
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3G1N
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![BU of 3g1n by Molmil](/molmil-images/mine/3g1n) | Catalytic domain of the human E3 ubiquitin-protein ligase HUWE1 | 分子名称: | E3 ubiquitin-protein ligase HUWE1, SODIUM ION | 著者 | Walker, J.R, Qiu, L, Li, Y, Davis, T, Tempel, W, Weigelt, J, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Botchkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | 登録日 | 2009-01-30 | 公開日 | 2009-02-17 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Hect Domain of Human HUWE1/MULE To be Published
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1RWI
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![BU of 1rwi by Molmil](/molmil-images/mine/1rwi) | Extracellular domain of Mycobacterium tuberculosis PknD | 分子名称: | CADMIUM ION, Serine/threonine-protein kinase pknD | 著者 | Good, M.C, Greenstein, A.E, Young, T.A, Ng, H.L, Alber, T, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2003-12-16 | 公開日 | 2004-04-27 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Sensor Domain of the Mycobacterium tuberculosis Receptor Ser/Thr Protein Kinase, PknD, forms a Highly Symmetric beta Propeller. J.Mol.Biol., 339, 2004
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2O9K
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![BU of 2o9k by Molmil](/molmil-images/mine/2o9k) | WDR5 in Complex with Dimethylated H3K4 Peptide | 分子名称: | H3 HISTONE, WD repeat protein 5 | 著者 | Min, J.R, Schuetz, A, Allali-Hassani, A, Martin, F, Loppnau, P, Vedadi, M, Weigelt, J, Sundstrom, M, Edwards, A.M, Arrowsmith, C.H, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC) | 登録日 | 2006-12-13 | 公開日 | 2006-12-19 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural Basis for Molecular Recognition and Presentation of Histone H3 by Wdr5. Embo J., 25, 2006
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1VA5
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![BU of 1va5 by Molmil](/molmil-images/mine/1va5) | Antigen 85C with octylthioglucoside in active site | 分子名称: | Antigen 85-C, octyl 1-thio-beta-D-glucopyranoside | 著者 | Ronning, D.R, Vissa, V, Besra, G.S, Belisle, J.T, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2004-02-11 | 公開日 | 2004-07-06 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | Mycobacterium tuberculosis Antigen 85A and 85C Structures Confirm Binding Orientation and Conserved Substrate Specificity J.Biol.Chem., 279, 2004
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1XX6
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![BU of 1xx6 by Molmil](/molmil-images/mine/1xx6) | X-ray structure of Clostridium acetobutylicum thymidine kinase with ADP. Northeast Structural Genomics Target CAR26. | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Thymidine kinase, ZINC ION | 著者 | Kuzin, A.P, Abashidze, M, Forouhar, F, Vorobiev, S.M, Acton, T.B, Ma, L.-C, Xiao, R, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2004-11-04 | 公開日 | 2004-12-21 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | X-ray structure of Clostridium acetobutylicum thymidine kinase with ADP. Northeast Structural Genomics Target CAR26. To be Published
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1XPW
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![BU of 1xpw by Molmil](/molmil-images/mine/1xpw) | Solution NMR Structure of human protein HSPCO34. Northeast Structural Genomics Target HR1958 | 分子名称: | LOC51668 protein | 著者 | Ramelot, T.A, Xiao, R, Ma, L.C, Acton, T.B, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2004-10-09 | 公開日 | 2004-11-09 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Improving NMR protein structure quality by Rosetta refinement: a molecular replacement study. Proteins, 75, 2009
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3DAL
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![BU of 3dal by Molmil](/molmil-images/mine/3dal) | Methyltransferase domain of human PR domain-containing protein 1 | 分子名称: | PR domain zinc finger protein 1 | 著者 | Amaya, M.F, Zeng, H, Antoshenko, T, Dong, A, Loppnau, P, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Plotnikov, A.N, Wu, H, Structural Genomics Consortium (SGC) | 登録日 | 2008-05-29 | 公開日 | 2008-08-12 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | The crystal structure
of methyltransferase domain of human PR domain-containing protein 1 To be Published
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