2O1O
Cryptosporidium parvum putative polyprenyl pyrophosphate synthase (cgd4_2550) in complex with risedronate.
Summary for 2O1O
Entry DOI | 10.2210/pdb2o1o/pdb |
Related | 2HER |
Descriptor | Putative farnesyl pyrophosphate synthase, MAGNESIUM ION, 1-HYDROXY-2-(3-PYRIDINYL)ETHYLIDENE BIS-PHOSPHONIC ACID, ... (4 entities in total) |
Functional Keywords | putative polyprenyl pyrophosphate synthase, structural genomics, structural genomics consortium, sgc, unknown function |
Biological source | Cryptosporidium parvum |
Total number of polymer chains | 2 |
Total formula weight | 86658.16 |
Authors | Chruszcz, M.,Artz, J.D.,Dong, A.,Dunford, J.,Lew, J.,Zhao, Y.,Kozieradski, I.,Kavanaugh, K.L.,Oppermann, U.,Sundstrom, M.,Weigelt, J.,Edwards, A.M.,Arrowsmith, C.H.,Bochkarev, A.,Hui, R.,Minor, W.,Structural Genomics Consortium (SGC) (deposition date: 2006-11-29, release date: 2006-12-12, Last modification date: 2023-08-30) |
Primary citation | Artz, J.D.,Dunford, J.E.,Arrowood, M.J.,Dong, A.,Chruszcz, M.,Kavanagh, K.L.,Minor, W.,Russell, R.G.,Ebetino, F.H.,Oppermann, U.,Hui, R. Targeting a uniquely nonspecific prenyl synthase with bisphosphonates to combat cryptosporidiosis Chem.Biol., 15:1296-1306, 2008 Cited by PubMed: 19101474DOI: 10.1016/j.chembiol.2008.10.017 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.42 Å) |
Structure validation
Download full validation report