5UQW
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![BU of 5uqw by Molmil](/molmil-images/mine/5uqw) | Crystal structure of human KRAS G12V mutant in complex with GDP | 分子名称: | GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | 著者 | Huang, C.S, Kaplan, A, Stockwell, B.R, Tong, L. | 登録日 | 2017-02-08 | 公開日 | 2017-03-22 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Multivalent Small-Molecule Pan-RAS Inhibitors. Cell, 168, 2017
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7Y04
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![BU of 7y04 by Molmil](/molmil-images/mine/7y04) | Hsp90-AhR-p23 complex | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Aryl hydrocarbon receptor, BERYLLIUM TRIFLUORIDE ION, ... | 著者 | Wen, Z.L, Zhai, Y.J, Zhu, Y, Sun, F. | 登録日 | 2022-06-03 | 公開日 | 2023-01-04 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Cryo-EM structure of the cytosolic AhR complex. Structure, 31, 2023
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2QXV
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![BU of 2qxv by Molmil](/molmil-images/mine/2qxv) | Structural basis of EZH2 recognition by EED | 分子名称: | Embryonic ectoderm development, Enhancer of zeste homolog 2 | 著者 | Han, Z. | 登録日 | 2007-08-13 | 公開日 | 2007-08-28 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | Structural basis of EZH2 recognition by EED Structure, 15, 2007
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7CYP
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![BU of 7cyp by Molmil](/molmil-images/mine/7cyp) | Complex of SARS-CoV-2 spike trimer with its neutralizing antibody HB27 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of HB27, ... | 著者 | Wang, X, Zhu, L. | 登録日 | 2020-09-04 | 公開日 | 2021-06-09 | 最終更新日 | 2022-02-23 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Double lock of a potent human therapeutic monoclonal antibody against SARS-CoV-2. Natl Sci Rev, 8, 2021
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7DFG
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![BU of 7dfg by Molmil](/molmil-images/mine/7dfg) | |
7DFH
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![BU of 7dfh by Molmil](/molmil-images/mine/7dfh) | |
7DOK
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![BU of 7dok by Molmil](/molmil-images/mine/7dok) | |
7DOI
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![BU of 7doi by Molmil](/molmil-images/mine/7doi) | |
7EBS
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![BU of 7ebs by Molmil](/molmil-images/mine/7ebs) | Crystal structure of juvenile hormone acid methyltransferase JHAMT from silkworm | 分子名称: | Juvenile hormone acid methyltransferase | 著者 | Guo, P.C, Zhang, Y.S, Zhang, L, Xu, H.Y, Xia, Q.Y. | 登録日 | 2021-03-11 | 公開日 | 2021-09-29 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Structural basis for juvenile hormone biosynthesis by the juvenile hormone acid methyltransferase. J.Biol.Chem., 297, 2021
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7EBX
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![BU of 7ebx by Molmil](/molmil-images/mine/7ebx) | Crystal structure of juvenile hormone acid methyltransferase JHAMT in complex with S-adenosyl-L-homocysteine. | 分子名称: | S-ADENOSYL-L-HOMOCYSTEINE, juvenile hormone acid methyltransferase | 著者 | Guo, P.C, Zhang, Y.S, Zhang, L, Xu, H.Y, Xia, Q.Y. | 登録日 | 2021-03-11 | 公開日 | 2021-09-29 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | 主引用文献 | Structural basis for juvenile hormone biosynthesis by the juvenile hormone acid methyltransferase. J.Biol.Chem., 297, 2021
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7EC0
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![BU of 7ec0 by Molmil](/molmil-images/mine/7ec0) | Crystal structure of juvenile hormone acid methyltransferase JHAMT in complex with S-Adenosyl homocysteine and methyl farnesoate | 分子名称: | Juvenile hormone acid methyltransferase, Methyl farnesoate, S-ADENOSYL-L-HOMOCYSTEINE | 著者 | Guo, P.C, Zhang, Y.S, Zhang, L, Xu, H.Y, Xia, Q.Y. | 登録日 | 2021-03-11 | 公開日 | 2021-09-29 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.494 Å) | 主引用文献 | Structural basis for juvenile hormone biosynthesis by the juvenile hormone acid methyltransferase. J.Biol.Chem., 297, 2021
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5Y36
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![BU of 5y36 by Molmil](/molmil-images/mine/5y36) | Cryo-EM structure of SpCas9-sgRNA-DNA ternary complex | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, MAGNESIUM ION, complementary DNA strand, ... | 著者 | Huang, Q, Li, G, Huai, C. | 登録日 | 2017-07-27 | 公開日 | 2017-12-06 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (5.2 Å) | 主引用文献 | Structural insights into DNA cleavage activation of CRISPR-Cas9 system Nat Commun, 8, 2017
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7EKE
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![BU of 7eke by Molmil](/molmil-images/mine/7eke) | Structure of SARS-CoV-2 spike receptor-binding domain F486L mutation complexed with human ACE2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike protein S1, ... | 著者 | Han, P.C, Su, C, Zhang, Y.F, Qi, J.X, Gao, G.F. | 登録日 | 2021-04-05 | 公開日 | 2021-11-03 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Molecular insights into receptor binding of recent emerging SARS-CoV-2 variants. Nat Commun, 12, 2021
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7EKC
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![BU of 7ekc by Molmil](/molmil-images/mine/7ekc) | Structure of SARS-CoV-2 Gamma variant spike receptor-binding domain complexed with human ACE2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | 著者 | Han, P.C, Su, C, Zhang, Y.F, Qi, J.X, Gao, G.F. | 登録日 | 2021-04-05 | 公開日 | 2021-11-03 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Molecular insights into receptor binding of recent emerging SARS-CoV-2 variants. Nat Commun, 12, 2021
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7EKG
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![BU of 7ekg by Molmil](/molmil-images/mine/7ekg) | Structure of SARS-CoV-2 Beta variant spike receptor-binding domain complexed with human ACE2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | 著者 | Han, P.C, Su, C, Zhang, Y.F, Qi, J.X, Gao, G.F. | 登録日 | 2021-04-05 | 公開日 | 2021-11-03 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.63 Å) | 主引用文献 | Molecular insights into receptor binding of recent emerging SARS-CoV-2 variants. Nat Commun, 12, 2021
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7EKH
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![BU of 7ekh by Molmil](/molmil-images/mine/7ekh) | Structure of SARS-CoV-2 spike receptor-binding domain Y453F mutation complexed with human ACE2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike protein S1, ... | 著者 | Han, P.C, Su, C, Zhang, Y.F, Qi, J.X, Gao, G.F. | 登録日 | 2021-04-05 | 公開日 | 2021-11-03 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Molecular insights into receptor binding of recent emerging SARS-CoV-2 variants. Nat Commun, 12, 2021
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7EKF
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![BU of 7ekf by Molmil](/molmil-images/mine/7ekf) | Structure of SARS-CoV-2 Alpha variant spike receptor-binding domain complexed with human ACE2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | 著者 | Han, P.C, Su, C, Zhang, Y.F, Qi, J.X, Gao, G.F. | 登録日 | 2021-04-05 | 公開日 | 2021-11-03 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Molecular insights into receptor binding of recent emerging SARS-CoV-2 variants. Nat Commun, 12, 2021
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8IK2
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![BU of 8ik2 by Molmil](/molmil-images/mine/8ik2) | RhlA exhibits dual thioesterase and acyltransferase activities during rhamnolipid biosynthesis | 分子名称: | (3~{S})-3-oxidanyldecanoic acid, 3-(3-hydroxydecanoyloxy)decanoate synthase | 著者 | Tang, T, Fu, L.H, Xie, W.H, Luo, Y.Z, Zhang, Y.T, Si, T. | 登録日 | 2023-02-28 | 公開日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.151 Å) | 主引用文献 | RhlA Exhibits Dual Thioesterase and Acyltransferase Activities during Rhamnolipid Biosynthesis Acs Catalysis, 13, 2023
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5Y87
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5F22
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5G0U
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![BU of 5g0u by Molmil](/molmil-images/mine/5g0u) | InhA in complex with a DNA encoded library hit | 分子名称: | 5-[(4-fluoranyl-3-phenoxy-phenyl)methylamino]-~{N}-methyl-6-[(1-pyridin-2-ylpiperidin-4-yl)amino]pyridine-3-carboxamide, ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE | 著者 | Read, J.A, Breed, J. | 登録日 | 2016-03-22 | 公開日 | 2016-11-30 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | 主引用文献 | Discovery of Cofactor-Specific, Bactericidal Mycobacterium Tuberculosis Inha Inhibitors Using DNA-Encoded Library Technology Proc.Natl.Acad.Sci.USA, 113, 2016
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5Y85
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5G0S
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![BU of 5g0s by Molmil](/molmil-images/mine/5g0s) | InhA in complex with a DNA encoded library hit | 分子名称: | ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADH], N-[4-[2-[(2S)-4-[2-(methylamino)-2-oxidanylidene-ethyl]-3-oxidanylidene-2-(phenylmethyl)piperazin-1-yl]-2-oxidanylidene-ethyl]cyclohexyl]-2-(3-methyl-1-benzothiophen-2-yl)ethanamide, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | 著者 | Read, J.A, Breed, J. | 登録日 | 2016-03-22 | 公開日 | 2016-11-30 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | 主引用文献 | Discovery of Cofactor-Specific, Bactericidal Mycobacterium Tuberculosis Inha Inhibitors Using DNA-Encoded Library Technology Proc.Natl.Acad.Sci.USA, 113, 2016
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5G0T
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![BU of 5g0t by Molmil](/molmil-images/mine/5g0t) | InhA in complex with a DNA encoded library hit | 分子名称: | 1-benzyl-N-[cis-4-(2-{[(4-fluorophenyl)methyl][2-(methylamino)-2-oxoethyl]amino}-2-oxoethyl)cyclohexyl]-5-methyl-1H-1,2,3-triazole-4-carboxamide, ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE | 著者 | Read, J.A, Breed, J. | 登録日 | 2016-03-22 | 公開日 | 2016-11-30 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | 主引用文献 | Discovery of Cofactor-Specific, Bactericidal Mycobacterium Tuberculosis Inha Inhibitors Using DNA-Encoded Library Technology Proc.Natl.Acad.Sci.USA, 113, 2016
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5G0V
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![BU of 5g0v by Molmil](/molmil-images/mine/5g0v) | InhA in complex with a DNA encoded library hit | 分子名称: | ENOYL-ACYL CARRIER PROTEIN REDUCTASE, MAGNESIUM ION, N-[2-(methylamino)-2-oxidanylidene-ethyl]-2-(4-pyrazol-1-ylphenyl)-N-(1-pyridin-2-ylpiperidin-4-yl)ethanamide, ... | 著者 | Read, J.A, Breed, J. | 登録日 | 2016-03-22 | 公開日 | 2016-11-30 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | Discovery of Cofactor-Specific, Bactericidal Mycobacterium Tuberculosis Inha Inhibitors Using DNA-Encoded Library Technology Proc.Natl.Acad.Sci.USA, 113, 2016
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