7DFG

Structure of COVID-19 RNA-dependent RNA polymerase bound to favipiravir

Summary for 7DFG

• Entry DOI: 10.2210/pdb7dfg/pdb
• EMDB information: 30663
• Descriptor: RNA (5'-R(P*AP*GP*AP*UP*UP*AP*AP*GP*UP*UP*AP*U)-3'), RNA (5'-R(P*CP*CP*CP*UP*AP*UP*AP*AP*CP*UP*UP*AP*AP*UP*CP*U)-3'), RNA-directed RNA polymerase, ... (10 entities in total)
• Functional Keywords: covid-19, rna polymerase, favipiravir binding, viral protein, viral protein-rna complex, viral protein/rna
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV); More
• Total number of polymer chains: 6
• Total formula weight: 171149.17

Authors

Li, Z.,Zhou, Z.,Yu, X. (deposition date: 2020-11-08, release date: 2021-11-17, Last modification date: 2024-05-29)

• Primary citation: Yin, W.,Luan, X.,Li, Z.,Xie, Y.,Zhou, Z.,Liu, J.,Gao, M.,Wang, X.,Zhou, F.,Wang, Q.,Wang, Q.,Shen, D.,Zhang, Y.,Tian, G.,Aisa, H.,Wei, D.,Jiang, Y.,Xiao, G.,Jiang, H.,Zhang, L.,Yu, X.,Shen, J.,Zhang, S.,Xu, H.; Structural basis for repurpose and design of nucleotide drugs for treating COVID-19; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.7 Å)