6NPV
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8H9O
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8H9W
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6NPU
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5GUE
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![BU of 5gue by Molmil](/molmil-images/mine/5gue) | Crystal structure of CotB2 (GGSPP/Mg2+-Bound Form) from Streptomyces melanosporofaciens | 分子名称: | Cyclooctat-9-en-7-ol synthase, MAGNESIUM ION, phosphonooxy-[(10E)-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraenyl]sulfanyl-phosphinic acid | 著者 | Tomita, T, Kim, S.-Y, Ozaki, T, Yoshida, A, Kuzuyama, T, Nishiyama, M. | 登録日 | 2016-08-28 | 公開日 | 2017-06-07 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural Insights into the CotB2-Catalyzed Cyclization of Geranylgeranyl Diphosphate to the Diterpene Cyclooctat-9-en-7-ol ACS Chem. Biol., 12, 2017
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5GUC
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![BU of 5guc by Molmil](/molmil-images/mine/5guc) | Crystal structure of CotB2 (apo form) from Streptomyces melanosporofaciens | 分子名称: | Cyclooctat-9-en-7-ol synthase, FORMIC ACID | 著者 | Tomita, T, Kim, S.-Y, Ozaki, T, Yoshida, A, Kuzuyama, T, Nishiyama, M. | 登録日 | 2016-08-28 | 公開日 | 2017-06-07 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural Insights into the CotB2-Catalyzed Cyclization of Geranylgeranyl Diphosphate to the Diterpene Cyclooctat-9-en-7-ol ACS Chem. Biol., 12, 2017
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7TVL
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![BU of 7tvl by Molmil](/molmil-images/mine/7tvl) | Viral AMG chitosanase V-Csn, apo structure | 分子名称: | GLYCEROL, SULFATE ION, Viral chitosanase V-Csn | 著者 | Smith, C.A, Wu, R, Buchko, G.W, Cort, J.R, Hofmockel, K.S, Jansson, J.K. | 登録日 | 2022-02-05 | 公開日 | 2022-10-05 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (0.89 Å) | 主引用文献 | Structural characterization of a soil viral auxiliary metabolic gene product - a functional chitosanase. Nat Commun, 13, 2022
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7TVN
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![BU of 7tvn by Molmil](/molmil-images/mine/7tvn) | Viral AMG chitosanase V-Csn, D148N mutant | 分子名称: | GLYCEROL, SULFATE ION, Viral chitosanase V-Csn D148N mutant | 著者 | Smith, C.A, Wu, R, Buchko, G.W, Cort, J.R, Hofmockel, K.S, Jansson, J.K. | 登録日 | 2022-02-05 | 公開日 | 2022-10-05 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Structural characterization of a soil viral auxiliary metabolic gene product - a functional chitosanase. Nat Commun, 13, 2022
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7TVO
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![BU of 7tvo by Molmil](/molmil-images/mine/7tvo) | Viral AMG chitosanase V-Csn, E157Q mutant | 分子名称: | GLYCEROL, SULFATE ION, Viral chitosanase V-Csn E157Q mutant | 著者 | Smith, C.A, Wu, R, Buchko, G.W, Cort, J.R, Hofmockel, K.S, Jansson, J.K. | 登録日 | 2022-02-05 | 公開日 | 2022-10-05 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | 主引用文献 | Structural characterization of a soil viral auxiliary metabolic gene product - a functional chitosanase. Nat Commun, 13, 2022
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6JUX
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![BU of 6jux by Molmil](/molmil-images/mine/6jux) | Crystal structure of human ALK2 kinase domain with R206H mutation in complex with RK-71807 | 分子名称: | 4-(1-ethyl-3-pyridin-3-yl-pyrazol-4-yl)-~{N}-(4-piperazin-1-ylphenyl)pyrimidin-2-amine, Activin receptor type-1, SULFATE ION | 著者 | Sakai, N, Mishima-Tsumagari, C, Matsumoto, T, Shirouzu, M. | 登録日 | 2019-04-15 | 公開日 | 2020-04-15 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structural Basis of Activin Receptor-Like Kinase 2 (R206H) Inhibition by Bis-heteroaryl Pyrazole-Based Inhibitors for the Treatment of Fibrodysplasia Ossificans Progressiva Identified by the Integration of Ligand-Based and Structure-Based Drug Design Approaches. Acs Omega, 5, 2020
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3OGL
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![BU of 3ogl by Molmil](/molmil-images/mine/3ogl) | Structure of COI1-ASK1 in complex with JA-isoleucine and the JAZ1 degron | 分子名称: | Coronatine-insensitive protein 1, JAZ1 incomplete degron peptide, N-({(1R,2S)-3-oxo-2-[(2Z)-pent-2-en-1-yl]cyclopentyl}acetyl)-L-isoleucine, ... | 著者 | Sheard, L.B, Tan, X, Mao, H, Withers, J, Ben-Nissan, G, Hinds, T.R, Hsu, F, Sharon, M, Browse, J, He, S.Y, Rizo, J, Howe, G.A, Zheng, N. | 登録日 | 2010-08-17 | 公開日 | 2010-10-13 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (3.18 Å) | 主引用文献 | Jasmonate perception by inositol-phosphate-potentiated COI1-JAZ co-receptor. Nature, 468, 2010
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3OGK
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![BU of 3ogk by Molmil](/molmil-images/mine/3ogk) | Structure of COI1-ASK1 in complex with coronatine and an incomplete JAZ1 degron | 分子名称: | (1S,2S)-2-ethyl-1-({[(3aS,4S,6R,7aS)-6-ethyl-1-oxooctahydro-1H-inden-4-yl]carbonyl}amino)cyclopropanecarboxylic acid, Coronatine-insensitive protein 1, JAZ1 incomplete degron peptide, ... | 著者 | Sheard, L.B, Tan, X, Mao, H, Withers, J, Ben-Nissan, G, Hinds, T.R, Hsu, F, Sharon, M, Browse, J, He, S.Y, Rizo, J, Howe, G.A, Zheng, N. | 登録日 | 2010-08-16 | 公開日 | 2010-10-13 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Jasmonate perception by inositol-phosphate-potentiated COI1-JAZ co-receptor. Nature, 468, 2010
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3PYY
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![BU of 3pyy by Molmil](/molmil-images/mine/3pyy) | Discovery and Characterization of a Cell-Permeable, Small-molecule c-Abl Kinase Activator that Binds to the Myristoyl Binding Site | 分子名称: | (5R)-5-[3-(4-fluorophenyl)-1-phenyl-1H-pyrazol-4-yl]imidazolidine-2,4-dione, 4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE, GLYCEROL, ... | 著者 | Yang, J, Campobasso, N, Biju, M.P, Fisher, K, Pan, X.Q, Cottom, J, Galbraith, S, Ho, T, Zhang, H, Hong, X, Ward, P, Hofmann, G, Siegfried, B. | 登録日 | 2010-12-13 | 公開日 | 2011-03-09 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Discovery and Characterization of a Cell-Permeable, Small-Molecule c-Abl Kinase Activator that Binds to the Myristoyl Binding Site. Chem.Biol., 18, 2011
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7EA6
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![BU of 7ea6 by Molmil](/molmil-images/mine/7ea6) | Crystal structure of TCR-017 ectodomain | 分子名称: | T cell receptor 017 alpha chain, T cell receptor 017 beta chain | 著者 | Nagae, M, Yamasaki, S. | 登録日 | 2021-03-06 | 公開日 | 2021-10-13 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.18000245 Å) | 主引用文献 | Identification of conserved SARS-CoV-2 spike epitopes that expand public cTfh clonotypes in mild COVID-19 patients. J.Exp.Med., 218, 2021
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6IO0
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![BU of 6io0 by Molmil](/molmil-images/mine/6io0) | Human IDH1 R132C mutant complexed with compound A. | 分子名称: | (2E)-3-{3-[3-(2,6-dichlorophenyl)-5-(propan-2-yl)-1,2-oxazole-4-carbonyl]-1-methyl-1H-indol-7-yl}prop-2-enoic acid, CITRIC ACID, GLYCEROL, ... | 著者 | Suzuki, M, Baba, D, Hanzawa, H. | 登録日 | 2018-10-29 | 公開日 | 2019-10-30 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | A Potent Blood-Brain Barrier-Permeable Mutant IDH1 Inhibitor Suppresses the Growth of Glioblastoma with IDH1 Mutation in a Patient-Derived Orthotopic Xenograft Model. Mol.Cancer Ther., 19, 2020
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3WEX
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![BU of 3wex by Molmil](/molmil-images/mine/3wex) | Crystal structure of HLA-DP5 in complex with Cry j 1-derived peptide (residues 214-222) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, MHC class II antigen | 著者 | Kusano, S, Kukimoto-Niino, M, Shirouzu, M, Yokoyama, S. | 登録日 | 2013-07-16 | 公開日 | 2014-07-23 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural basis for the specific recognition of the major antigenic peptide from the Japanese cedar pollen allergen Cry j 1 by HLA-DP5 J. Mol. Biol., 426, 2014
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3WHA
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![BU of 3wha by Molmil](/molmil-images/mine/3wha) | Hsp90 alpha N-terminal domain in complex with a tricyclic inhibitor | 分子名称: | 4-{[4-amino-6-(5-chloro-1H,3H-benzo[de]isochromen-6-yl)-1,3,5-triazin-2-yl]sulfanyl}butanamide, GLYCEROL, Heat shock protein HSP 90-alpha, ... | 著者 | Fukami, T.A, Ono, N. | 登録日 | 2013-08-23 | 公開日 | 2014-01-29 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Design and synthesis of 2-amino-6-(1H,3H-benzo[de]isochromen-6-yl)-1,3,5-triazines as novel Hsp90 inhibitors Bioorg.Med.Chem., 22, 2014
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8KAD
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![BU of 8kad by Molmil](/molmil-images/mine/8kad) | Crystal structure of an antibody light chain tetramer with 3D domain swapping | 分子名称: | Antibody light chain | 著者 | Sakai, T, Mashima, T, Kobayashi, N, Ogata, H, Uda, T, Hifumi, E, Hirota, S. | 登録日 | 2023-08-02 | 公開日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural and thermodynamic insights into antibody light chain tetramer formation through 3D domain swapping. Nat Commun, 14, 2023
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5H18
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![BU of 5h18 by Molmil](/molmil-images/mine/5h18) | Crystal structure of catalytic domain of UGGT (UDP-glucose-bound form) from Thermomyces dupontii | 分子名称: | CALCIUM ION, GLYCEROL, UGGT, ... | 著者 | Satoh, T, Zhu, T, Toshimori, T, Kamikubo, H, Uchihashi, T, Kato, K. | 登録日 | 2016-10-08 | 公開日 | 2017-09-27 | 最終更新日 | 2017-11-01 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Visualisation of a flexible modular structure of the ER folding-sensor enzyme UGGT. Sci Rep, 7, 2017
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4YDQ
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![BU of 4ydq by Molmil](/molmil-images/mine/4ydq) | Crystal Structure of Prolyl-tRNA Synthetase (PRS) from Plasmodium falciparum in complex with Halofuginone and AMPPNP | 分子名称: | 7-bromo-6-chloro-3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}quinazolin-4(3H)-one, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | 著者 | Jain, V, Yogavel, M, Sharma, A. | 登録日 | 2015-02-23 | 公開日 | 2015-05-20 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure of Prolyl-tRNA Synthetase-Halofuginone Complex Provides Basis for Development of Drugs against Malaria and Toxoplasmosis Structure, 23, 2015
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7CUF
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7CUG
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7C3G
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![BU of 7c3g by Molmil](/molmil-images/mine/7c3g) | Crystal structure of human ALK2 kinase domain with R206H mutation in complex with a bicyclic pyrazole inhibitor RK-73134 | 分子名称: | 1,2-ETHANEDIOL, Activin receptor type-1, SULFATE ION, ... | 著者 | Sakai, N, Mishima-Tsumagari, C, Matsumoto, T, Shirouzu, M. | 登録日 | 2020-05-12 | 公開日 | 2021-03-03 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.802 Å) | 主引用文献 | Novel bicyclic pyrazoles as potent ALK2 (R206H) inhibitors for the treatment of fibrodysplasia ossificans progressiva. Bioorg.Med.Chem.Lett., 38, 2021
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4HA6
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![BU of 4ha6 by Molmil](/molmil-images/mine/4ha6) | Crystal structure of pyridoxine 4-oxidase - pyridoxamine complex | 分子名称: | 4-(AMINOMETHYL)-5-(HYDROXYMETHYL)-2-METHYLPYRIDIN-3-OL, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... | 著者 | Mugo, A.N, Kobayashi, J, Mikami, B, Yagi, T. | 登録日 | 2012-09-25 | 公開日 | 2013-06-05 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.095 Å) | 主引用文献 | Crystal structure of pyridoxine 4-oxidase from Mesorhizobium loti. Biochim.Biophys.Acta, 1834, 2013
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7DZW
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![BU of 7dzw by Molmil](/molmil-images/mine/7dzw) | Apo spike protein from SARS-CoV2 | 分子名称: | Spike glycoprotein | 著者 | Liu, Y, Soh, W.T, Li, S, Kishikawa, J, Hirose, M, Kato, T, Standley, D, Okada, M, Arase, H. | 登録日 | 2021-01-26 | 公開日 | 2021-06-02 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.45 Å) | 主引用文献 | An infectivity-enhancing site on the SARS-CoV-2 spike protein targeted by antibodies. Cell, 184, 2021
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