6V3Z
 
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7UFZ
 | | Crystal structure of TDP1 complexed with compound XZ768 | | 分子名称: | (4-{[(4S)-2-phenylimidazo[1,2-a]pyridin-3-yl]amino}phenyl)phosphonic acid, 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, ... | | 著者 | Lountos, G.T, Zhao, X.Z, Wang, W, Tropea, J.E, Needle, D, Pommier, Y, Burke, T.R. | | 登録日 | 2022-03-23 | | 公開日 | 2023-04-12 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.559 Å) | | 主引用文献 | Phosphonic acid-containing inhibitors of tyrosyl-DNA phosphodiesterase 1.
Front Chem, 10, 2022
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7UJV
 | | Structure of PHD2 in complex with HIF2a-CODD | | 分子名称: | Egl nine homolog 1, Endothelial PAS domain-containing protein 1, FE (III) ION, ... | | 著者 | Ferens, F.G, Tarade, D, Lee, J.E, Ohh, M. | | 登録日 | 2022-03-31 | | 公開日 | 2023-04-05 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Deficiency in PHD2-mediated hydroxylation of HIF2 alpha underlies Pacak-Zhuang syndrome.
Commun Biol, 7, 2024
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7UFY
 | | Crystal structure of TDP1 complexed with compound XZ766 | | 分子名称: | 1,2-ETHANEDIOL, Tyrosyl-DNA phosphodiesterase 1, [(4-{[(4S)-2,7-diphenylimidazo[1,2-a]pyridin-3-yl]amino}phenyl)methyl]phosphonic acid | | 著者 | Lountos, G.T, Zhao, X.Z, Wang, W, Tropea, J.E, Needle, D, Pommier, Y, Burke, T.R. | | 登録日 | 2022-03-23 | | 公開日 | 2023-04-12 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.584 Å) | | 主引用文献 | Phosphonic acid-containing inhibitors of tyrosyl-DNA phosphodiesterase 1.
Front Chem, 10, 2022
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4HPP
 | | Crystal structure of novel glutamine synthase homolog | | 分子名称: | CALCIUM ION, GLUTAMIC ACID, MAGNESIUM ION, ... | | 著者 | Ladner, J.E, Atanasova, V, Dolezelova, Z, Parsons, J.F. | | 登録日 | 2012-10-24 | | 公開日 | 2012-12-26 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure and Activity of PA5508, a Hexameric Glutamine Synthetase Homologue.
Biochemistry, 51, 2012
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4HMC
 | | Crystal structure of cold-adapted chitinase from Moritella marina | | 分子名称: | Chitinase 60, GLYCEROL, SODIUM ION | | 著者 | Malecki, P.H, Vorgias, C.E, Raczynska, J.E, Rypniewski, W. | | 登録日 | 2012-10-18 | | 公開日 | 2013-05-01 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structure of a complete four-domain chitinase from Moritella marina, a marine psychrophilic bacterium
Acta Crystallogr.,Sect.D, 69, 2013
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9G9R
 | | Crystal structure of PbdA bound to p-ethylbenzoate | | 分子名称: | 4-ethylbenzoic acid, Cytochrome P450 CYP199, GLYCEROL, ... | | 著者 | Hinchen, D.J, Wolf, M.E, Eltis, L.D, McGeehan, J.E. | | 登録日 | 2024-07-25 | | 公開日 | 2024-10-02 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Characterization of a cytochrome P450 that catalyzes the O-demethylation of lignin-derived benzoates.
J.Biol.Chem., 300, 2024
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9G9Q
 | | Crystal structure of PbdA bound to p-methoxybenzoate. | | 分子名称: | 4-METHOXYBENZOIC ACID, Cytochrome P450 CYP199, GLYCEROL, ... | | 著者 | Hinchen, D.J, Wolf, M.E, Eltis, L.D, McGeehan, J.E. | | 登録日 | 2024-07-25 | | 公開日 | 2024-10-02 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | | 主引用文献 | Characterization of a cytochrome P450 that catalyzes the O-demethylation of lignin-derived benzoates.
J.Biol.Chem., 300, 2024
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9G9S
 | | Crystal structure of PbdA bound to veratrate | | 分子名称: | 3,4-dimethoxybenzoic acid, Cytochrome P450 CYP199, GLYCEROL, ... | | 著者 | Hinchen, D.J, Wolf, M.E, Eltis, L.D, McGeehan, J.E. | | 登録日 | 2024-07-25 | | 公開日 | 2024-10-02 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Characterization of a cytochrome P450 that catalyzes the O-demethylation of lignin-derived benzoates.
J.Biol.Chem., 300, 2024
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4J75
 | | Crystal Structure of a parasite tRNA synthetase, product-bound | | 分子名称: | GLYCEROL, TRYPTOPHANYL-5'AMP, Tryptophanyl-tRNA synthetase | | 著者 | Koh, C.Y, Kim, J.E, Verlinde, C.L.M.J, Hol, W.G.J. | | 登録日 | 2013-02-12 | | 公開日 | 2013-05-22 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal structures of Plasmodium falciparum cytosolic tryptophanyl-tRNA synthetase and its potential as a target for structure-guided drug design.
Mol.Biochem.Parasitol., 189, 2013
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4IPM
 | | Crystal structure of a GH7 family cellobiohydrolase from Limnoria quadripunctata in complex with thiocellobiose | | 分子名称: | ACETATE ION, CALCIUM ION, GH7 family protein, ... | | 著者 | McGeehan, J.E, Martin, R.N.A, Streeter, S.D, Cragg, S.M, Guille, M.J, Schnorr, K.M, Kern, M, Bruce, N.C, McQueen-Mason, S.J. | | 登録日 | 2013-01-10 | | 公開日 | 2013-06-12 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.14 Å) | | 主引用文献 | Structural characterization of a unique marine animal family 7 cellobiohydrolase suggests a mechanism of cellulase salt tolerance.
Proc.Natl.Acad.Sci.USA, 110, 2013
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4JCG
 | | Recombinant wild type Nitrosomonas europaea cytochrome c552 | | 分子名称: | Cytochrome c-552, HEME C | | 著者 | Wedekind, J.E, Can, M, Krucinska, J, Bren, K.L. | | 登録日 | 2013-02-21 | | 公開日 | 2013-08-14 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | | 主引用文献 | Structural Characterization of Nitrosomonas europaea Cytochrome c-552 Variants with Marked Differences in Electronic Structure.
Chembiochem, 14, 2013
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4JF3
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7UPZ
 | | Structural basis for cell type specific DNA binding of C/EBPbeta: the case of cell cycle inhibitor p15INK4b promoter | | 分子名称: | CCAAT/enhancer-binding protein beta, DNA (5'-D(*AP*TP*TP*CP*TP*TP*AP*AP*GP*AP*AP*AP*GP*AP*CP*G)-3'), DNA (5'-D(*TP*CP*GP*TP*CP*TP*TP*TP*CP*TP*TP*AP*AP*GP*AP*A)-3') | | 著者 | Lountos, G.T, Cherry, S, Tropea, J.E, Wlodawer, A, Miller, M. | | 登録日 | 2022-04-18 | | 公開日 | 2022-11-23 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.487 Å) | | 主引用文献 | Structural basis for cell type specific DNA binding of C/EBP beta : The case of cell cycle inhibitor p15INK4b promoter.
J.Struct.Biol., 214, 2022
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4HMD
 | | Crystal structure of cold-adapted chitinase from Moritella marina with a reaction intermediate - oxazolinium ion (NGO) | | 分子名称: | 2-METHYL-4,5-DIHYDRO-(1,2-DIDEOXY-ALPHA-D-GLUCOPYRANOSO)[2,1-D]-1,3-OXAZOLE, 2-acetamido-2-deoxy-beta-D-glucopyranose, Chitinase 60, ... | | 著者 | Malecki, P.H, Vorgias, C.E, Raczynska, J.E, Rypniewski, W. | | 登録日 | 2012-10-18 | | 公開日 | 2013-05-01 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | | 主引用文献 | Structure of a complete four-domain chitinase from Moritella marina, a marine psychrophilic bacterium
Acta Crystallogr.,Sect.D, 69, 2013
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4HME
 | | Crystal structure of cold-adapted chitinase from Moritella marina with a reaction product - NAG2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Chitinase 60, GLYCEROL, ... | | 著者 | Malecki, P.H, Vorgias, C.E, Raczynska, J.E, Rypniewski, W. | | 登録日 | 2012-10-18 | | 公開日 | 2013-05-01 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | | 主引用文献 | Structure of a complete four-domain chitinase from Moritella marina, a marine psychrophilic bacterium
Acta Crystallogr.,Sect.D, 69, 2013
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4K1E
 | | Atomic resolution crystal structures of Kallikrein-Related Peptidase 4 complexed with a modified SFTI inhibitor FCQR | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Kallikrein-4, LITHIUM ION, ... | | 著者 | Ilyichova, O.V, Swedberg, J.E, de Veer, S.J, Sit, K.C, Harris, J.M, Buckle, A.M. | | 登録日 | 2013-04-04 | | 公開日 | 2014-04-09 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Direct and indirect mechanisms of KLK4 inhibition revealed by structure and dynamics
Sci Rep, 6, 2016
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4IQ6
 | | Gsk-3beta with inhibitor 6-chloro-N-cyclohexyl-4-(1H-pyrrolo[2,3-b]pyridin-3-yl)pyridin-2-amine | | 分子名称: | 6-chloro-N-cyclohexyl-4-(1H-pyrrolo[2,3-b]pyridin-3-yl)pyridin-2-amine, Glycogen synthase kinase-3 beta | | 著者 | Tong, Y, Stewart, K.D, Florjancic, A.S, Harlan, J.E, Merta, P.J, Przytulinska, M, Soni, N, Swinger, K.S, Zhu, H, Johnson, E.F, Shoemaker, A.R, Penning, T.D. | | 登録日 | 2013-01-10 | | 公開日 | 2013-04-24 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.12 Å) | | 主引用文献 | Azaindole-Based Inhibitors of Cdc7 Kinase: Impact of the Pre-DFG Residue, Val 195.
ACS Med Chem Lett, 4, 2013
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4K0E
 | | X-ray crystal structure of a heavy metal efflux pump, crystal form II | | 分子名称: | Heavy metal cation tricomponent efflux pump ZneA(CzcA-like), ZINC ION | | 著者 | Pak, J.E, Ngonlong Ekende, E, Vandenbussche, G, Stroud, R.M, Center for Structures of Membrane Proteins (CSMP) | | 登録日 | 2013-04-03 | | 公開日 | 2013-10-16 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (3.713 Å) | | 主引用文献 | Structures of intermediate transport states of ZneA, a Zn(II)/proton antiporter.
Proc.Natl.Acad.Sci.USA, 110, 2013
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4K0J
 | | X-ray crystal structure of a heavy metal efflux pump, crystal form I | | 分子名称: | Heavy metal cation tricomponent efflux pump ZneA(CzcA-like), ZINC ION | | 著者 | Pak, J.E, Stroud, R.M, Ngonlong Ekende, E, Vandenbussche, G, Center for Structures of Membrane Proteins (CSMP) | | 登録日 | 2013-04-04 | | 公開日 | 2013-10-16 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structures of intermediate transport states of ZneA, a Zn(II)/proton antiporter.
Proc.Natl.Acad.Sci.USA, 110, 2013
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4KGA
 | | Crystal structure of kallikrein-related peptidase 4 | | 分子名称: | 1,2-ETHANEDIOL, Kallikrein-4, NICKEL (II) ION | | 著者 | Ilyichova, O.V, Swedberg, J.E, de Veer, S.J, Sit, K.C, Harris, J.M, Buckle, A.M. | | 登録日 | 2013-04-29 | | 公開日 | 2014-04-30 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | | 主引用文献 | Direct and indirect mechanisms of KLK4 inhibition revealed by structure and dynamics
Sci Rep, 6, 2016
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4KGM
 | | Bacterial tRNA(HIS) Guanylyltransferase (Thg1)-Like Protein in complex with ATP | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... | | 著者 | Hyde, S.J, Rao, B.S, Eckenroth, B.E, Jackman, J.E, Doublie, S. | | 登録日 | 2013-04-29 | | 公開日 | 2013-08-14 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.361 Å) | | 主引用文献 | Structural Studies of a Bacterial tRNA(HIS) Guanylyltransferase (Thg1)-Like Protein, with Nucleotide in the Activation and Nucleotidyl Transfer Sites.
Plos One, 8, 2013
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7U6O
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4KQQ
 | | CRYSTAL STRUCTURE OF PENICILLIN-BINDING PROTEIN 3 FROM PSEUDOMONAS AERUGINOSA IN COMPLEX WITH (5S)-Penicilloic Acid | | 分子名称: | (2S,4S)-2-[(R)-carboxy{[(2R)-2-{[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino}-2-phenylacetyl]amino}methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, CHLORIDE ION, GLYCEROL, ... | | 著者 | Nettleship, J.E, Stuart, D.I, Owens, R.J, Ren, J. | | 登録日 | 2013-05-15 | | 公開日 | 2013-11-06 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Binding of (5S)-Penicilloic Acid to Penicillin Binding Protein 3.
Acs Chem.Biol., 8, 2013
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4JPR
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