1DAU
| Analog of dickerson-drew DNA dodecamer with 6'-alpha-methyl carbocyclic thymidines, NMR, minimized average structure | 分子名称: | DNA (5'-D(*CP*GP*CP*GP*AP*AP*(T32)P*(T32)P*CP*GP*CP*G)-3') | 著者 | Denisov, A, Bekiroglu, S, Maltseva, T, Sandstrom, A, Altmann, K.-H, Egli, M, Chattopadhyaya, J. | 登録日 | 1998-01-21 | 公開日 | 1998-05-27 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | The solution conformation of a carbocyclic analog of the Dickerson-Drew dodecamer: comparison with its own X-ray structure and that of the NMR structure of the native counterpart. J.Biomol.Struct.Dyn., 16, 1998
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4R1Z
| Zebra fish cytochrome P450 17A1 with Abiraterone | 分子名称: | Abiraterone, Cyp17a1 protein, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Pallan, P.S, Egli, M. | 登録日 | 2014-08-08 | 公開日 | 2014-12-31 | 最終更新日 | 2015-03-04 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Structural and Kinetic Basis of Steroid 17 alpha, 20-Lyase Activity in Teleost Fish Cytochrome P450 17A1 and Its Absence in Cytochrome P450 17A2. J.Biol.Chem., 290, 2015
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1EH4
| BINARY COMPLEX OF CASEIN KINASE-1 FROM S. POMBE WITH AN ATP COMPETITIVE INHIBITOR, IC261 | 分子名称: | 3-[(2,4,6-TRIMETHOXY-PHENYL)-METHYLENE]-INDOLIN-2-ONE, CASEIN KINASE-1, SULFATE ION | 著者 | Mashhoon, N, Demaggio, A.J, Tereshko, V, Bergmeier, S.C, Egli, M, Hoekstra, M.F, Kuret, J. | 登録日 | 2000-02-18 | 公開日 | 2001-09-19 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal Structure of a Conformation-Selective Casein Kinase-1 Inhibitor J.Biol.Chem., 275, 2000
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1CS7
| SYNTHETIC DNA HAIRPIN WITH STILBENEDIETHER LINKER | 分子名称: | 5'-D(GP*(BRU)P*TP*TP*TP*GP*(S02)*CP*AP*AP*AP*AP*C)-3', STRONTIUM ION | 著者 | Lewis, F.D, Liu, X, Wu, Y, Miller, S.E, Wasielewski, M.R, Letsinger, R.L, Sanishvili, R, Joachimiak, A, Tereshko, V, Egli, M. | 登録日 | 1999-08-17 | 公開日 | 2001-10-19 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structure and Photoinduced Electron Transfer in Exceptionally Stable Synthetic DNA Hairpins with Stilbenediether Linkers J.Am.Chem.Soc., 121, 1999
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1I2Y
| 1.66 A STRUCTURE OF A-DUPLEX WITH BULGED ADENOSINE, SPERMINE FORM | 分子名称: | DNA/RNA (5'-R(*GP*CP*G)-D(P*AP*TP*AP*T)-R(P*AP*CP*GP*U)-3'), SPERMINE | 著者 | Tereshko, V, Wallace, S, Usman, N, Wincott, F, Egli, M. | 登録日 | 2001-02-12 | 公開日 | 2001-04-21 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | 主引用文献 | X-ray crystallographic observation of "in-line" and "adjacent" conformations in a bulged self-cleaving RNA/DNA hybrid. RNA, 7, 2001
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1U9I
| Crystal Structure of Circadian Clock Protein KaiC with Phosphorylation Sites | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, KaiC, MAGNESIUM ION | 著者 | Xu, Y, Mori, T, Pattanayek, R, Pattanayek, S, Egli, M, Johnson, C.H. | 登録日 | 2004-08-09 | 公開日 | 2005-04-19 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Identification of key phosphorylation sites in the circadian clock protein KaiC by crystallographic and mutagenetic analyses PROC.NATL.ACAD.SCI.USA, 101, 2004
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6B82
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1RXA
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1I2X
| 2.4 A STRUCTURE OF A-DUPLEX WITH BULGED ADENOSINE, SPERMIDINE FORM | 分子名称: | DNA/RNA (5'-R(*GP*CP*G)-D(P*AP*TP*AP*T)-R(P*AP*CP*GP*U)-3'), SPERMIDINE | 著者 | Tereshko, V, Wallace, S, Usman, N, Wincott, F, Egli, M. | 登録日 | 2001-02-12 | 公開日 | 2001-04-21 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | X-ray crystallographic observation of "in-line" and "adjacent" conformations in a bulged self-cleaving RNA/DNA hybrid. RNA, 7, 2001
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1RXB
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1TF7
| Crystal Structure of Circadian Clock Protein KaiC | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, KaiC | 著者 | Pattanayek, R, Wang, J, Mori, T, Xu, Y, Johnson, C.H, Egli, M. | 登録日 | 2004-05-26 | 公開日 | 2004-08-24 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Visualizing a Circadian Clock Protein; Crystal Structure of KaiC and Functional Insights Mol.Cell, 15, 2004
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1VRO
| Selenium-Assisted Nucleic Acid Crystallography: Use of Phosphoroselenoates for MAD Phasing of a DNA Structure | 分子名称: | 5'-D(*CP*(GMS)P*CP*GP*CP*G)-3', MAGNESIUM ION, SPERMINE | 著者 | Wilds, C.J, Pattanayek, R, Pan, C, Wawrzak, Z, Egli, M. | 登録日 | 2005-04-14 | 公開日 | 2005-04-19 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Selenium-Assisted Nucleic Acid Crystallography: Use of Phosphoroselenoates for MAD Phasing of a DNA Structure J.Am.Chem.Soc., 124, 2002
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4O3R
| Crystal structure of human polymerase eta extending an 8-oxog dna lesion: post insertion of 8-oxog-da pair | 分子名称: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*A)-3'), DNA (5'-D(*CP*AP*TP*GP*(8OG)P*TP*GP*AP*CP*GP*CP*T)-3'), ... | 著者 | Patra, A, Egli, M. | 登録日 | 2013-12-18 | 公開日 | 2014-04-30 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | 主引用文献 | Kinetics, Structure, and Mechanism of 8-Oxo-7,8-dihydro-2'-deoxyguanosine Bypass by Human DNA Polymerase eta J.Biol.Chem., 289, 2014
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4O0M
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4O3O
| Crystal structure of human polymerase eta inserting datp opposite an 8-oxog containing dna template | 分子名称: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*(8OG)P*AP*TP*GP*AP*CP*GP*CP*T)-3'), ... | 著者 | Patra, A, Egli, M. | 登録日 | 2013-12-18 | 公開日 | 2014-04-30 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.698 Å) | 主引用文献 | Kinetics, Structure, and Mechanism of 8-Oxo-7,8-dihydro-2'-deoxyguanosine Bypass by Human DNA Polymerase eta J.Biol.Chem., 289, 2014
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4O3S
| Crystal structure of human polymerase eta extending an 8-oxog dna lesion: post insertion of 8-oxog-dc pair | 分子名称: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*C)-3'), DNA (5'-D(*CP*AP*TP*GP*(8OG)P*TP*GP*AP*CP*GP*CP*T)-3'), ... | 著者 | Patra, A, Egli, M. | 登録日 | 2013-12-18 | 公開日 | 2014-04-30 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.717 Å) | 主引用文献 | Kinetics, Structure, and Mechanism of 8-Oxo-7,8-dihydro-2'-deoxyguanosine Bypass by Human DNA Polymerase eta J.Biol.Chem., 289, 2014
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4O3N
| Crystal structure of human dna polymerase eta in ternary complex with native dna and incoming nucleotide (dcp) | 分子名称: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*GP*AP*TP*GP*AP*CP*GP*CP*T)-3'), ... | 著者 | Patra, A, Egli, M. | 登録日 | 2013-12-18 | 公開日 | 2014-04-30 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.579 Å) | 主引用文献 | Kinetics, Structure, and Mechanism of 8-Oxo-7,8-dihydro-2'-deoxyguanosine Bypass by Human DNA Polymerase eta J.Biol.Chem., 289, 2014
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4O3P
| Crystal structure of human polymerase eta inserting dctp opposite an 8-oxog containing dna template | 分子名称: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*(8OG)P*AP*TP*GP*AP*CP*GP*CP*T)-3'), ... | 著者 | Patra, A, Egli, M. | 登録日 | 2013-12-18 | 公開日 | 2014-04-30 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | 主引用文献 | Kinetics, Structure, and Mechanism of 8-Oxo-7,8-dihydro-2'-deoxyguanosine Bypass by Human DNA Polymerase eta J.Biol.Chem., 289, 2014
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4O3Q
| Crystal structure of human polymerase eta inserting dgtp opposite an 8-oxog containing dna template | 分子名称: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*(8OG)P*AP*TP*GP*AP*CP*GP*CP*T)-3'), ... | 著者 | Patra, A, Egli, M. | 登録日 | 2013-12-18 | 公開日 | 2014-04-30 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | 主引用文献 | Kinetics, Structure, and Mechanism of 8-Oxo-7,8-dihydro-2'-deoxyguanosine Bypass by Human DNA Polymerase eta J.Biol.Chem., 289, 2014
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4O41
| Amide linked RNA | 分子名称: | AMIDE LINKED RNA, STRONTIUM ION | 著者 | Pallan, P.S, Egli, M. | 登録日 | 2013-12-18 | 公開日 | 2014-07-09 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Amides are excellent mimics of phosphate internucleoside linkages and are well tolerated in short interfering RNAs. Nucleic Acids Res., 42, 2014
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4RNN
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4RUA
| Crystal structure of Y-family DNA polymerase Dpo4 bypassing a MeFapy-dG adduct | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase IV, ... | 著者 | Patra, A, Banerjee, S, Stone, M.P, Egli, M. | 登録日 | 2014-11-18 | 公開日 | 2015-08-05 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.07 Å) | 主引用文献 | Structural Basis for Error-Free Bypass of the 5-N-Methylformamidopyrimidine-dG Lesion by Human DNA Polymerase eta and Sulfolobus solfataricus P2 Polymerase IV. J.Am.Chem.Soc., 137, 2015
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4RU9
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5DG8
| CRYSTAL STRUCTURE OF HUMAN DNA POLYMERASE ETA INSERTING dAMPNPP ACROSS A DNA TEMPLATE CONTAINING 1,N6-ETHENODEOXYADENOSINE LESION | 分子名称: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*(EDA)P*AP*TP*GP*AP*CP*GP*CP*T)-3'), ... | 著者 | Patra, A, Egli, M. | 登録日 | 2015-08-27 | 公開日 | 2016-06-08 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | 主引用文献 | Structural and Kinetic Analysis of Miscoding Opposite the DNA Adduct 1,N6-Ethenodeoxyadenosine by Human Translesion DNA Polymerase eta. J.Biol.Chem., 291, 2016
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5DG7
| CRYSTAL STRUCTURE OF HUMAN DNA POLYMERASE ETA INSERTING dTTP ACROSS A DNA TEMPLATE CONTAINING 1,N6-ETHENODEOXYADENOSINE LESION | 分子名称: | CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*(EDA)P*AP*TP*GP*AP*CP*GP*CP*T)-3'), ... | 著者 | Patra, A, Egli, M. | 登録日 | 2015-08-27 | 公開日 | 2016-06-08 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | 主引用文献 | Structural and Kinetic Analysis of Miscoding Opposite the DNA Adduct 1,N6-Ethenodeoxyadenosine by Human Translesion DNA Polymerase eta. J.Biol.Chem., 291, 2016
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