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3NKD
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BU of 3nkd by Molmil
Structure of CRISP-associated protein Cas1 from Escherichia coli str. K-12
分子名称: CRISPR-associated protein Cas1
著者Nocek, B, Skarina, T, Beloglazova, N, Savchenko, A, Joachimiak, A, Yakunin, A.
登録日2010-06-18
公開日2010-08-25
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献A dual function of the CRISPR-Cas system in bacterial antivirus immunity and DNA repair.
Mol.Microbiol., 79, 2011
4HQQ
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BU of 4hqq by Molmil
Crystal structure of RV144-elicited antibody CH58
分子名称: CH58 Fab heavy chain, CH58 Fab light chain
著者McLellan, J.S, Haynes, B.F, Kwong, P.D.
登録日2012-10-25
公開日2013-02-06
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Vaccine Induction of Antibodies against a Structurally Heterogeneous Site of Immune Pressure within HIV-1 Envelope Protein Variable Regions 1 and 2.
Immunity, 38, 2013
3NKE
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BU of 3nke by Molmil
High resolution structure of the C-terminal domain CRISP-associated protein Cas1 from Escherichia coli str. K-12
分子名称: 1,2-ETHANEDIOL, SULFATE ION, SULFITE ION, ...
著者Nocek, B, Skarina, T, Beloglazova, N, Savchenko, A, Joachimiak, A, Yakunin, A.
登録日2010-06-18
公開日2010-08-25
最終更新日2014-12-17
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献A dual function of the CRISPR-Cas system in bacterial antivirus immunity and DNA repair.
Mol.Microbiol., 79, 2011
5VDU
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BU of 5vdu by Molmil
Human cyclic GMP-AMP synthase (cGAS) in complex with Compound F2
分子名称: 2-(pyridin-2-yl)pyrimidine, Cyclic GMP-AMP synthase, ZINC ION
著者Byrnes, L.J, Hall, J.D.
登録日2017-04-03
公開日2017-09-27
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.729 Å)
主引用文献The catalytic mechanism of cyclic GMP-AMP synthase (cGAS) and implications for innate immunity and inhibition.
Protein Sci., 26, 2017
5VDV
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BU of 5vdv by Molmil
Human cyclic GMP-AMP synthase (cGAS) in complex with Compound F3
分子名称: Cyclic GMP-AMP synthase, SULFATE ION, ZINC ION, ...
著者Byrnes, L.J, Hall, J.D.
登録日2017-04-03
公開日2017-09-27
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.998 Å)
主引用文献The catalytic mechanism of cyclic GMP-AMP synthase (cGAS) and implications for innate immunity and inhibition.
Protein Sci., 26, 2017
1JZT
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BU of 1jzt by Molmil
Crystal structure of yeast ynu0, YNL200c
分子名称: CHLORIDE ION, Hypothetical 27.5 kDa protein in SPX19-GCR2 intergenic region
著者Jiang, J.-S, Manning, N.O, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2001-09-17
公開日2001-09-26
最終更新日2021-02-03
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Crystal Structure of Yeast Hypothetical Protein YNU0_YEAST
To be Published
4L4W
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BU of 4l4w by Molmil
Structure of EspG3 chaperone from the type VII (ESX-3) secretion system
分子名称: EspG3
著者Korotkov, K.V.
登録日2013-06-09
公開日2014-06-11
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.036 Å)
主引用文献Structural Variability of EspG Chaperones from Mycobacterial ESX-1, ESX-3, and ESX-5 Type VII Secretion Systems.
J. Mol. Biol., 431, 2019
5IDI
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BU of 5idi by Molmil
Structure of beta glucosidase 1A from Thermotoga neapolitana, mutant E349A
分子名称: 1,4-beta-D-glucan glucohydrolase, ACETATE ION
著者Kulkarni, T, Nordberg Karlsson, E, Logan, D.T.
登録日2016-02-24
公開日2017-02-08
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of beta-glucosidase 1A from Thermotoga neapolitana and comparison of active site mutants for hydrolysis of flavonoid glucosides.
Proteins, 85, 2017
2IVS
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BU of 2ivs by Molmil
Crystal structure of non-phosphorylated RET tyrosine kinase domain
分子名称: 2',3'- cyclic AMP, FORMIC ACID, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RET
著者Knowles, P.P, Murray-Rust, J, McDonald, N.Q.
登録日2006-06-16
公開日2006-08-14
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure and Chemical Inhibition of the Ret Tyrosine Kinase Domain.
J.Biol.Chem., 281, 2006
2H2Q
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BU of 2h2q by Molmil
Crystal structure of Trypanosoma cruzi Dihydrofolate Reductase-Thymidylate synthase
分子名称: 2'-DEOXYURIDINE-5'-MONOPHOSPHATE, Bifunctional dihydrofolate reductase-thymidylate synthase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Senkovich, O, Schormann, N, Chattopadhyay, D.
登録日2006-05-19
公開日2008-04-08
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure-based approach to pharmacophore identification, in silico screening, and three-dimensional quantitative structure-activity relationship studies for inhibitors of Trypanosoma cruzi dihydrofolate reductase function.
Proteins, 73, 2008
3G9L
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BU of 3g9l by Molmil
JNK3 bound to (Z)-1-((6-fluoro-4H-benzo[d][1,3]dioxin-8-yl)methyl)-3-(hydroxyimino)-4-styrylindolin-2-one
分子名称: (3Z)-1-[(6-fluoro-4H-1,3-benzodioxin-8-yl)methyl]-4-[(E)-2-phenylethenyl]-1H-indole-2,3-dione 3-oxime, Mitogen-activated protein kinase 10
著者Jacobs, M.D.
登録日2009-02-13
公開日2009-04-28
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure-based design and parallel synthesis of N-benzyl isatin oximes as JNK3 MAP kinase inhibitors.
Bioorg.Med.Chem.Lett., 19, 2009
3G9N
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BU of 3g9n by Molmil
JNK3 bound to (Z)-1-((6-fluoro-4H-benzo[d][1,3]dioxin-8-yl)methyl)-3-(hydroxyimino)-4-phenylindolin-2-one
分子名称: (3Z)-1-[(6-fluoro-4H-1,3-benzodioxin-8-yl)methyl]-4-phenyl-1H-indole-2,3-dione 3-oxime, Mitogen-activated protein kinase 10
著者Jacobs, M.D.
登録日2009-02-13
公開日2009-02-24
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure-based design and parallel synthesis of N-benzyl isatin oximes as JNK3 MAP kinase inhibitors.
Bioorg.Med.Chem.Lett., 19, 2009
3NS7
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BU of 3ns7 by Molmil
Succinic Acid Amides as P2-P3 Replacements for Inhibitors of Interleukin-1beta Converting Enzyme (ICE or Caspase 1)
分子名称: (3S)-4-hydroxy-3-{[(2S)-4-{[2-(2-methyl-1H-benzimidazol-1-yl)ethyl]amino}-2-(1-methylethyl)-4-oxobutanoyl]amino}butanoic acid, Caspase-1
著者Galatsis, P.
登録日2010-07-01
公開日2011-08-17
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Succinic acid amides as P2-P3 replacements for inhibitors of interleukin-1beta converting enzyme (ICE or caspase 1).
Bioorg.Med.Chem.Lett., 20, 2010
4HPY
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BU of 4hpy by Molmil
Crystal structure of RV144-elicited antibody CH59 in complex with V2 peptide
分子名称: CH59 Fab heavy chain, CH59 Fab light chain, Envelope glycoprotein gp160, ...
著者McLellan, J.S, Gorman, J, Haynes, B.F, Kwong, P.D.
登録日2012-10-24
公開日2013-02-06
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Vaccine Induction of Antibodies against a Structurally Heterogeneous Site of Immune Pressure within HIV-1 Envelope Protein Variable Regions 1 and 2.
Immunity, 38, 2013
5T7V
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BU of 5t7v by Molmil
Methicillin Resistant, Linezolid resistant Staphylococcus aureus 70S ribosome (delta S145 uL3)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Belousoff, M.J, Lithgow, T, Eyal, Z, Yonath, A, Radjainia, M.
登録日2016-09-06
公開日2017-05-31
最終更新日2019-12-11
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structural Basis for Linezolid Binding Site Rearrangement in theStaphylococcus aureusRibosome.
MBio, 8, 2017
2IVT
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BU of 2ivt by Molmil
Crystal structure of phosphorylated RET tyrosine kinase domain
分子名称: ADENOSINE MONOPHOSPHATE, FORMIC ACID, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RET PRECURSOR
著者Knowles, P.P, Murray-Rust, J, McDonald, N.Q.
登録日2006-06-16
公開日2006-08-14
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure and chemical inhibition of the RET tyrosine kinase domain.
J. Biol. Chem., 281, 2006
4HPO
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BU of 4hpo by Molmil
Crystal structure of RV144-elicited antibody CH58 in complex with V2 peptide
分子名称: CH58 Fab heavy chain, CH58 Fab light chain, Envelope glycoprotein gp160, ...
著者McLellan, J.S, Gorman, J, Haynes, B.F, Kwong, P.D.
登録日2012-10-24
公開日2013-02-06
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.694 Å)
主引用文献Vaccine Induction of Antibodies against a Structurally Heterogeneous Site of Immune Pressure within HIV-1 Envelope Protein Variable Regions 1 and 2.
Immunity, 38, 2013
2IVV
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BU of 2ivv by Molmil
Crystal structure of phosphorylated RET tyrosine kinase domain complexed with the inhibitor PP1
分子名称: 1-TER-BUTYL-3-P-TOLYL-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-YLAMINE, FORMIC ACID, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RET PRECURSOR
著者Knowles, P.P, Murray-Rust, J, McDonald, N.Q.
登録日2006-06-16
公開日2006-08-14
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structure and chemical inhibition of the RET tyrosine kinase domain.
J. Biol. Chem., 281, 2006
2IVU
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BU of 2ivu by Molmil
Crystal structure of phosphorylated RET tyrosine kinase domain complexed with the inhibitor ZD6474
分子名称: FORMIC ACID, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RET PRECURSOR, Vandetanib
著者Knowles, P.P, Murray-Rust, J, McDonald, N.Q.
登録日2006-06-16
公開日2006-08-10
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure and chemical inhibition of the RET tyrosine kinase domain.
J. Biol. Chem., 281, 2006
7DNF
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BU of 7dnf by Molmil
DARPin 63_B7 in complex with V3-IY (MN) crown mimetic
分子名称: DARPin 63_B7, SULFATE ION, V3-IY (MN) crown mimetic peptide
著者Wu, Y, Plueckthun, A.
登録日2020-12-09
公開日2021-12-15
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Distinct conformations of the HIV-1 V3 loop crown are targetable for broad neutralization.
Nat Commun, 12, 2021
7DNG
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BU of 7dng by Molmil
DARPin 63_B7 in complex with linear V3-crown (MN) peptide
分子名称: DARPin 63_B7, linear V3-crown (MN) peptide
著者Wu, Y, Plueckthun, A.
登録日2020-12-09
公開日2021-12-15
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献Distinct conformations of the HIV-1 V3 loop crown are targetable for broad neutralization.
Nat Commun, 12, 2021
7DNE
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BU of 7dne by Molmil
DARPin 5m3_D12 in complex with V3-IY (MN) crown mimetic
分子名称: DARPin 5m3_D12, V3-IY (MN) crown mimetic peptide
著者Wu, Y, Plueckthun, A.
登録日2020-12-09
公開日2021-12-22
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Distinct conformations of the HIV-1 V3 loop crown are targetable for broad neutralization.
Nat Commun, 12, 2021
1BI2
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BU of 1bi2 by Molmil
STRUCTURE OF APO-AND HOLO-DIPHTHERIA TOXIN REPRESSOR
分子名称: DIPHTHERIA TOXIN REPRESSOR
著者Pohl, E, Hol, W.G.J.
登録日1998-06-21
公開日1999-06-22
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Motion of the DNA-binding domain with respect to the core of the diphtheria toxin repressor (DtxR) revealed in the crystal structures of apo- and holo-DtxR.
J.Biol.Chem., 273, 1998
6IUV
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BU of 6iuv by Molmil
Crystal structure of influenza A virus H5 hemagglutinin globular head in complex with the Fab of antibody 3C11
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 3C11 Heavy Chain, 3C11 Light Chain, ...
著者Wang, P, Zuo, Y, Sun, J, Zhang, L, Wang, X.
登録日2018-11-30
公開日2019-01-16
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.332 Å)
主引用文献Structural and functional definition of a vulnerable site on the hemagglutinin of highly pathogenic avian influenza A virus H5N1.
J. Biol. Chem., 294, 2019
7EKM
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BU of 7ekm by Molmil
Mitochondrial outer membrane protein
分子名称: ATP-binding cassette sub-family B member 6, mitochondrial
著者Zhang, S.S.
登録日2021-04-05
公開日2021-08-25
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Molecular insights into the human ABCB6 transporter.
Cell Discov, 7, 2021

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