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2MVN
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BU of 2mvn by Molmil
Solution structure of eEF1Bdelta CAR domain in TCTP-bound state
分子名称: Elongation factor 1-delta
著者Wu, H, Feng, Y.
登録日2014-10-09
公開日2015-02-04
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Evolutionarily Conserved Binding of Translationally Controlled Tumor Protein to Eukaryotic Elongation Factor 1B.
J.Biol.Chem., 290, 2015
1SX3
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BU of 1sx3 by Molmil
GroEL14-(ATPgammaS)14
分子名称: MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, POTASSIUM ION, ...
著者Chaudhry, C, Horwich, A.L, Brunger, A.T, Adams, P.D.
登録日2004-03-30
公開日2005-03-01
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Exploring the structural dynamics of the E.coli chaperonin GroEL using translation-libration-screw crystallographic refinement of intermediate states.
J.Mol.Biol., 342, 2004
7XRI
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BU of 7xri by Molmil
Feruloyl esterase mutant -S106A
分子名称: Cinnamoyl esterase, ethyl (2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate
著者Hwang, J.S, Lee, J.H, Do, H, Lee, C.W.
登録日2022-05-10
公開日2023-05-17
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献Feruloyl Esterase ( La Fae) from Lactobacillus acidophilus : Structural Insights and Functional Characterization for Application in Ferulic Acid Production.
Int J Mol Sci, 24, 2023
7Y6D
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BU of 7y6d by Molmil
Cryo-EM structure of SARS-CoV-2 Delta variant spike proteins on intact virions: 3 Closed RBD
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者Xu, J, Song, Y, Li, S.
登録日2022-06-20
公開日2023-06-07
実験手法ELECTRON MICROSCOPY (4.39 Å)
主引用文献In situ architecture and membrane fusion of SARS-CoV-2 Delta variant.
Proc.Natl.Acad.Sci.USA, 120, 2023
2Q99
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BU of 2q99 by Molmil
Crystal Structure of Saccharopine Dehydrogenase from Saccharomyces cerevisiae
分子名称: Saccharopine dehydrogenase [NAD+, L-lysine-forming
著者Berghuis, A.M, Burk, D.L.
登録日2007-06-12
公開日2007-11-06
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Structural Studies of the Final Enzyme in the alpha-Aminoadipate Pathway-Saccharopine Dehydrogenase from Saccharomyces cerevisiae
J.Mol.Biol., 373, 2007
5JI2
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BU of 5ji2 by Molmil
HslU L199Q in HslUV complex
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent protease ATPase subunit HslU, ATP-dependent protease subunit HslV, ...
著者Grant, R.A, Sauer, R.T, Schmitz, K.R, Baytshtok, V.
登録日2016-04-21
公開日2016-11-30
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.307 Å)
主引用文献A Structurally Dynamic Region of the HslU Intermediate Domain Controls Protein Degradation and ATP Hydrolysis.
Structure, 24, 2016
6JQS
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BU of 6jqs by Molmil
Structure of Transcription factor, GerE
分子名称: DNA-binding response regulator
著者Lee, J.H, Lee, C.W.
登録日2019-04-01
公開日2019-04-24
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Crystal structure of a transcription factor, GerE (PaGerE), from spore-forming bacterium Paenisporosarcina sp. TG-14.
Biochem.Biophys.Res.Commun., 513, 2019
5JI3
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HslUV complex
分子名称: 2'-DEOXYADENOSINE-5'-DIPHOSPHATE, ATP-dependent protease ATPase subunit HslU, ATP-dependent protease subunit HslV
著者Grant, R.A, Sauer, R.T, Schmitz, K.R, Baytshtok, V.
登録日2016-04-21
公開日2016-12-07
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献A Structurally Dynamic Region of the HslU Intermediate Domain Controls Protein Degradation and ATP Hydrolysis.
Structure, 24, 2016
7WKS
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Apo state of AtPIN3
分子名称: Auxin efflux carrier component 3
著者Su, N.
登録日2022-01-11
公開日2022-08-10
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structures and mechanisms of the Arabidopsis auxin transporter PIN3.
Nature, 609, 2022
7WKW
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NPA bound state of AtPIN3
分子名称: 2-(naphthalen-1-ylcarbamoyl)benzoic acid, Auxin efflux carrier component 3
著者Su, N.
登録日2022-01-11
公開日2022-08-10
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (2.62 Å)
主引用文献Structures and mechanisms of the Arabidopsis auxin transporter PIN3.
Nature, 609, 2022
5YSZ
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BU of 5ysz by Molmil
transcriptional regulator CelR-cellobiose complex
分子名称: GLYCEROL, Transcriptional regulator, LacI family, ...
著者Fu, Y, Yeom, S.Y, Lee, D.H, Lee, S.G.
登録日2017-11-16
公開日2018-08-22
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.631 Å)
主引用文献Structural and functional analyses of the cellulase transcription regulator CelR
FEBS Lett., 592, 2018
7XAF
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BU of 7xaf by Molmil
The crystal structure of TrkA kinase in complex with 4^6,14-dimethyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-10-oxo-5-oxa-11,14-diaza-1(3,6)-imidazo[1,2-b]pyridazina-4(1,3)-benzenacyclo- tetradecaphan-2-yne-45-carboxamide
分子名称: 4^6,14-dimethyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-10-oxo-5-oxa-11,14-diaza-1(3,6)-imidazo[1,2-b]pyridazina-4(1,3)-benzenacyclo-tetradecaphan-2-yne-45-carboxamide, High affinity nerve growth factor receptor
著者Zhang, Z.M, Wang, Y.J.
登録日2022-03-17
公開日2022-06-01
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.001182 Å)
主引用文献Discovery of the First Highly Selective and Broadly Effective Macrocycle-Based Type II TRK Inhibitors that Overcome Clinically Acquired Resistance.
J.Med.Chem., 65, 2022
7X83
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BU of 7x83 by Molmil
Cryo-EM structure of the TMEM106B fibril from normal elder
分子名称: Transmembrane protein 106B
著者Xia, W.C, Zhao, Q.Y, Fan, Y, Sun, Y.P, Tao, Y.Q, Liu, C.
登録日2022-03-11
公開日2022-06-15
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Generic amyloid fibrillation of TMEM106B in patient with Parkinson's disease dementia and normal elders.
Cell Res., 32, 2022
7X84
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BU of 7x84 by Molmil
Cryo-EM structure of the TMEM106B fibril from Parkinson's disease dementia
分子名称: Transmembrane protein 106B
著者Zhao, Q.Y, Xia, W.C, Fan, Y, Sun, Y.P, Tao, Y.Q, Liu, C.
登録日2022-03-11
公開日2022-06-15
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Generic amyloid fibrillation of TMEM106B in patient with Parkinson's disease dementia and normal elders.
Cell Res., 32, 2022
4FYO
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BU of 4fyo by Molmil
Crystal structure of spleen tyrosine kinase complexed with N-{(S)-1-[7-(3,4-Dimethoxy-phenylamino)-thiazolo[5,4-d]pyrimidin-5-yl]-pyrrolidin-3-yl}-terephthalamic acid
分子名称: 4-{[(3S)-1-{7-[(3,4-dimethoxyphenyl)amino][1,3]thiazolo[5,4-d]pyrimidin-5-yl}pyrrolidin-3-yl]carbamoyl}benzoic acid, Tyrosine-protein kinase SYK
著者Kuglstatter, A, Slade, M.
登録日2012-07-05
公開日2013-01-30
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Rational design of highly selective spleen tyrosine kinase inhibitors.
J.Med.Chem., 55, 2012
4FZ6
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BU of 4fz6 by Molmil
Crystal structure of spleen tyrosine kinase complexed with [6-((S)-2-Methyl-pyrrolidin-1-yl)-pyridin-2-yl]-(6-phenyl-imidazo[1,2-b]pyridazin-8-yl)-amine
分子名称: N-{6-[(2S)-2-methylpyrrolidin-1-yl]pyridin-2-yl}-6-phenylimidazo[1,2-b]pyridazin-8-amine, Tyrosine-protein kinase SYK
著者Kuglstatter, A, Slade, M.
登録日2012-07-06
公開日2013-01-30
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Rational design of highly selective spleen tyrosine kinase inhibitors.
J.Med.Chem., 55, 2012
7C4X
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BU of 7c4x by Molmil
Crystal structure of germination protease from the spore-forming bacterium Paenisporosarcina sp. TG-20 in its inactive form
分子名称: germination protease
著者Lee, J.H, Lee, C.W.
登録日2020-05-18
公開日2021-03-31
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural insights into the psychrophilic germinal protease PaGPR and its autoinhibitory loop.
J.Microbiol, 58, 2020
8GTZ
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BU of 8gtz by Molmil
Crystal structure of exopolyphosphatase (PPX) mutant E137A from Zymomonas mobilis in complex with magnesium ions
分子名称: CHLORIDE ION, MAGNESIUM ION, Ppx/GppA phosphatase
著者Lu, Z, Wang, J, Zhang, B.
登録日2022-09-09
公開日2023-09-13
実験手法X-RAY DIFFRACTION (1.56 Å)
主引用文献Crystal structure of exopolyphosphatase (PPX) from Zymomonas mobilis in complex with magnesium ions
To Be Published
4FYN
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BU of 4fyn by Molmil
Crystal structure of spleen tyrosine kinase complexed with 3-(8-{4-[Ethyl-(2-hydroxy-ethyl)-amino]-phenylamino}-imidazo[1,2-a]pyrazin-5-yl)-phenol
分子名称: 3-[8-({4-[ethyl(2-hydroxyethyl)amino]phenyl}amino)imidazo[1,2-a]pyrazin-5-yl]phenol, Tyrosine-protein kinase SYK
著者Kuglstatter, A, Villasenor, A.G.
登録日2012-07-05
公開日2013-01-30
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.318 Å)
主引用文献Rational design of highly selective spleen tyrosine kinase inhibitors.
J.Med.Chem., 55, 2012
7ZBV
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BU of 7zbv by Molmil
Crystal structure of the peptidase domain of collagenase G from Clostridium histolyticum in complex with a diphosphonate-based inhibitor
分子名称: CALCIUM ION, Collagenase ColG, TRIS-HYDROXYMETHYL-METHYL-AMMONIUM, ...
著者Schoenauer, E, Brandstetter, H.
登録日2022-03-24
公開日2022-11-09
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Discovery and Characterization of Synthesized and FDA-Approved Inhibitors of Clostridial and Bacillary Collagenases.
J.Med.Chem., 65, 2022
7Z5U
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BU of 7z5u by Molmil
Crystal structure of the peptidase domain of collagenase G from Clostridium histolyticum in complex with a hydroxamate-based inhibitor
分子名称: (2~{R})-~{N}-[2-[4-[(2-acetamidophenoxy)methyl]-1,2,3-triazol-1-yl]ethyl]-2-(2-methylpropyl)-~{N}'-oxidanyl-propanediamide, CALCIUM ION, Collagenase ColG, ...
著者Schoenauer, E, Brandstetter, H.
登録日2022-03-10
公開日2022-11-09
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Discovery and Characterization of Synthesized and FDA-Approved Inhibitors of Clostridial and Bacillary Collagenases.
J.Med.Chem., 65, 2022
7YSE
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BU of 7yse by Molmil
Crystal structure of E. coli heterotetrameric GlyRS in complex with tRNA
分子名称: Glycine--tRNA ligase alpha subunit, Glycine--tRNA ligase beta subunit, MAGNESIUM ION, ...
著者Han, L, Ju, Y, Zhou, H.
登録日2022-08-12
公開日2023-02-01
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.907 Å)
主引用文献The binding mode of orphan glycyl-tRNA synthetase with tRNA supports the synthetase classification and reveals large domain movements.
Sci Adv, 9, 2023
7BXZ
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BU of 7bxz by Molmil
Crystal structure of the aminoglycoside 6'-N-acetyltransferase from Enterococcus faecium
分子名称: Aminoglycoside 6'-N-acetyltransferase
著者Kwon, S, Park, H.H.
登録日2020-04-21
公開日2020-08-12
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.502 Å)
主引用文献Structural analysis of a novel substrate-free form of the aminoglycoside 6'-N-acetyltransferase from Enterococcus faecium.
Acta Crystallogr.,Sect.F, 76, 2020
7E8N
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BU of 7e8n by Molmil
Crystal structure of Type II citrate synthase (HyCS) from Hymenobacter sp. PAMC 26554
分子名称: CITRIC ACID, Citrate synthase
著者Park, S.-H, Lee, C.W, Bae, D.-W, Lee, J.H.
登録日2021-03-02
公開日2022-01-12
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural basis of the cooperative activation of type II citrate synthase (HyCS) from Hymenobacter sp. PAMC 26554.
Int.J.Biol.Macromol., 183, 2021
7YW3
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Crystal structure of tRNA 2'-phosphotransferase from Homo sapiens
分子名称: 1,2-ETHANEDIOL, [[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{S},4~{R},5~{R})-3,4-bis(oxidanyl)-5-phosphonooxy-oxolan-2-yl]methyl hydrogen phosphate, tRNA 2'-phosphotransferase 1
著者Yang, X.Y, Liu, X.H.
登録日2022-08-21
公開日2023-07-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural and biochemical insights into the molecular mechanism of TRPT1 for nucleic acid ADP-ribosylation.
Nucleic Acids Res., 51, 2023

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