8H38
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![BU of 8h38 by Molmil](/molmil-images/mine/8h38) | Cryo-EM Structure of the KBTBD2-CRL3~N8-CSN(mutate) complex | 分子名称: | COP9 signalosome complex subunit 1, COP9 signalosome complex subunit 2, COP9 signalosome complex subunit 3, ... | 著者 | Hu, Y, Mao, Q, Chen, Z, Sun, L. | 登録日 | 2022-10-08 | 公開日 | 2023-10-11 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (4.25 Å) | 主引用文献 | Dynamic molecular architecture and substrate recruitment of cullin3-RING E3 ligase CRL3 KBTBD2. Nat.Struct.Mol.Biol., 31, 2024
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5WQ4
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5XJS
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7V9P
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7V9Q
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7V9O
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7V9N
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![BU of 7v9n by Molmil](/molmil-images/mine/7v9n) | Crystal structure of the lanthipeptide zinc-metallopeptidase EryP from saccharopolyspora erythraea in closed state | 分子名称: | ACETATE ION, Alanine aminopeptidase, CALCIUM ION, ... | 著者 | Zhao, C, Zhao, N.L, Bao, R. | 登録日 | 2021-08-26 | 公開日 | 2022-05-11 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Conformational remodeling enhances activity of lanthipeptide zinc-metallopeptidases. Nat.Chem.Biol., 18, 2022
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7CYV
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![BU of 7cyv by Molmil](/molmil-images/mine/7cyv) | Crystal structure of FD20, a neutralizing single-chain variable fragment (scFv) in complex with SARS-CoV-2 Spike receptor-binding domain (RBD) | 分子名称: | Spike protein S1, The heavy chain variable region of the scFv FD20,The light chain variable region of the scFv FD20, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)][alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Li, Y, Li, T, Lai, Y, Cai, H, Yao, H, Li, D. | 登録日 | 2020-09-04 | 公開日 | 2021-09-15 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.13 Å) | 主引用文献 | Uncovering a conserved vulnerability site in SARS-CoV-2 by a human antibody. Embo Mol Med, 13, 2021
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5XJR
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5XJQ
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8JM9
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8JMI
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8JMA
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8JME
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8JMH
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7WV9
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![BU of 7wv9 by Molmil](/molmil-images/mine/7wv9) | Allosteric modulator ZCZ011 binding to CP55940-bound cannabinoid receptor 1 in complex with Gi protein | 分子名称: | 2-[(1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohexyl]-5-(2-methyloctan-2-yl)phenol, 6-methyl-3-[(1S)-2-nitro-1-thiophen-2-yl-ethyl]-2-phenyl-1H-indole, Cannabinoid receptor 1, ... | 著者 | Xu, Z, Shao, Z. | 登録日 | 2022-02-10 | 公開日 | 2022-06-15 | 最終更新日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (3.36 Å) | 主引用文献 | Molecular mechanism of allosteric modulation for the cannabinoid receptor CB1. Nat.Chem.Biol., 18, 2022
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8K0B
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5X0W
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![BU of 5x0w by Molmil](/molmil-images/mine/5x0w) | Molecular mechanism for the binding between Sharpin and HOIP | 分子名称: | E3 ubiquitin-protein ligase RNF31, Sharpin | 著者 | Liu, J, Li, F, Cheng, X, Pan, L. | 登録日 | 2017-01-23 | 公開日 | 2017-10-18 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural Insights into SHARPIN-Mediated Activation of HOIP for the Linear Ubiquitin Chain Assembly Cell Rep, 21, 2017
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7XGW
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7XY9
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![BU of 7xy9 by Molmil](/molmil-images/mine/7xy9) | Cryo-EM structure of secondary alcohol dehydrogenases TbSADH after carrier-free immobilization based on weak intermolecular interactions | 分子名称: | MAGNESIUM ION, NADP-dependent isopropanol dehydrogenase, ZINC ION | 著者 | Chen, Q, Li, X, Yang, F, Qu, G, Sun, Z.T, Wang, Y.J. | 登録日 | 2022-06-01 | 公開日 | 2023-06-07 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (2.12 Å) | 主引用文献 | Active and stable alcohol dehydrogenase-assembled hydrogels via synergistic bridging of triazoles and metal ions. Nat Commun, 14, 2023
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8HBC
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![BU of 8hbc by Molmil](/molmil-images/mine/8hbc) | Crystal structure of the CysR-CTLD3 fragment of human DEC205 | 分子名称: | Lymphocyte antigen 75 | 著者 | Kong, D, Yu, B, Hu, Z, Cheng, C, Cao, L, He, Y. | 登録日 | 2022-10-28 | 公開日 | 2023-11-01 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (3.35 Å) | 主引用文献 | Interaction of human dendritic cell receptor DEC205/CD205 with keratins. J.Biol.Chem., 300, 2024
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7DSZ
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![BU of 7dsz by Molmil](/molmil-images/mine/7dsz) | Crystal structure of Amuc_1102 from Akkermansia muciniphila | 分子名称: | Amuc_1102, CHLORIDE ION | 著者 | Xiang, R, Wang, J, Wang, Y, Zhang, M, Wang, M. | 登録日 | 2021-01-04 | 公開日 | 2021-02-24 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Amuc_1102 fromAkkermansia muciniphilaadopts animmunoglobulin-like fold related to archaeal type IV pilus Biochem.Biophys.Res.Commun., 547, 2021
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7DSC
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![BU of 7dsc by Molmil](/molmil-images/mine/7dsc) | CALHM1 open state with disordered CTH | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Calcium homeostasis modulator 1 | 著者 | Ren, Y, Yang, X, Shen, Y.Q. | 登録日 | 2020-12-30 | 公開日 | 2022-01-05 | 最終更新日 | 2023-01-25 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Cryo-EM structure of the heptameric calcium homeostasis modulator 1 channel. J.Biol.Chem., 298, 2022
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7DSD
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![BU of 7dsd by Molmil](/molmil-images/mine/7dsd) | CALHM1 close state with disordered CTH | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Calcium homeostasis modulator 1 | 著者 | Ren, Y, Yang, X, Shen, Y.Q. | 登録日 | 2020-12-30 | 公開日 | 2022-01-05 | 最終更新日 | 2023-01-25 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Cryo-EM structure of the heptameric calcium homeostasis modulator 1 channel. J.Biol.Chem., 298, 2022
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7DSE
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![BU of 7dse by Molmil](/molmil-images/mine/7dse) | CALHM1 close state with ordered CTH | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Calcium homeostasis modulator 1 | 著者 | Ren, Y, Yang, X, Shen, Y.Q. | 登録日 | 2020-12-30 | 公開日 | 2022-01-05 | 最終更新日 | 2023-01-25 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Cryo-EM structure of the heptameric calcium homeostasis modulator 1 channel. J.Biol.Chem., 298, 2022
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