8WQB
 
 | | Cryo-EM structure of CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CCDC89 (conformation 2) | | 分子名称: | Coiled-coil domain-containing protein 89, Cullin-2, E3 ubiquitin-protein ligase RBX1, ... | | 著者 | Chen, X, Zhang, K, Xu, C. | | 登録日 | 2023-10-11 | | 公開日 | 2024-04-03 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (3.37 Å) | | 主引用文献 | Mechanism of Psi-Pro/C-degron recognition by the CRL2 FEM1B ubiquitin ligase.
Nat Commun, 15, 2024
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8WQH
 | | cryo-EM structure of neddylated CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CCDC89 (conformation 2) | | 分子名称: | Coiled-coil domain-containing protein 89, Cullin-2, E3 ubiquitin-protein ligase RBX1, ... | | 著者 | Chen, X, Zhang, K, Xu, C. | | 登録日 | 2023-10-11 | | 公開日 | 2024-04-03 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (3.44 Å) | | 主引用文献 | Mechanism of Psi-Pro/C-degron recognition by the CRL2 FEM1B ubiquitin ligase.
Nat Commun, 15, 2024
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7CFM
 | | Cryo-EM structure of the P395-bound GPBAR-Gs complex | | 分子名称: | 2-(ethylamino)-6-[3-(4-propan-2-ylphenyl)propanoyl]-7,8-dihydro-5H-pyrido[4,3-d]pyrimidine-4-carboxamide, CHOLESTEROL, G-protein coupled bile acid receptor 1, ... | | 著者 | Yang, F, Mao, C, Guo, L, Lin, J, Ming, Q, Xiao, P, Wu, X, Shen, Q, Guo, S, Shen, D, Lu, R, Zhang, L, Huang, S, Ping, Y, Zhang, C, Ma, C, Zhang, K, Liang, X, Shen, Y, Nan, F, Yi, F, Luca, V, Zhou, J, Jiang, C, Sun, J, Xie, X, Yu, X, Zhang, Y. | | 登録日 | 2020-06-27 | | 公開日 | 2020-09-09 | | 最終更新日 | 2020-12-02 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structural basis of GPBAR activation and bile acid recognition.
Nature, 587, 2020
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7CFN
 | | Cryo-EM structure of the INT-777-bound GPBAR-Gs complex | | 分子名称: | (2S,4R)-4-[(3R,5S,6R,7R,8R,9S,10S,12S,13R,14S,17R)-6-ethyl-10,13-dimethyl-3,7,12-tris(oxidanyl)-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methyl-pentanoic acid, CHOLESTEROL, G-protein coupled bile acid receptor 1, ... | | 著者 | Yang, F, Mao, C, Guo, L, Lin, J, Ming, Q, Xiao, P, Wu, X, Shen, Q, Guo, S, Shen, D, Lu, R, Zhang, L, Huang, S, Ping, Y, Zhang, C, Ma, C, Zhang, K, Liang, X, Shen, Y, Nan, F, Yi, F, Luca, V, Zhou, J, Jiang, C, Sun, J, Xie, X, Yu, X, Zhang, Y. | | 登録日 | 2020-06-27 | | 公開日 | 2020-09-09 | | 最終更新日 | 2021-04-07 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structural basis of GPBAR activation and bile acid recognition.
Nature, 587, 2020
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8K3Y
 | | The "5+1" heteromeric structure of Lon protease consisting of a spiral pentamer with Y224S mutation and an N-terminal-truncated monomeric E613K mutant | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Lon protease | | 著者 | Li, S, Hsieh, K.Y, Kuo, C.I, Zhang, K, Chang, C.I. | | 登録日 | 2023-07-17 | | 公開日 | 2023-10-25 | | 最終更新日 | 2023-11-29 | | 実験手法 | ELECTRON MICROSCOPY (4.42 Å) | | 主引用文献 | A 5+1 assemble-to-activate mechanism of the Lon proteolytic machine.
Nat Commun, 14, 2023
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8XVD
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8XVB
 | | Cryo-EM structure of ATP-DNA-MuB filaments | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent target DNA activator B, DNA (5'-D(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), ... | | 著者 | Zhao, X, Zhang, K, Li, S. | | 登録日 | 2024-01-14 | | 公開日 | 2024-08-14 | | 最終更新日 | 2024-08-21 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Elucidating the Architectural dynamics of MuB filaments in bacteriophage Mu DNA transposition
Nat Commun, 15, 2024
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8XVC
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7KEK
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3U9G
 | | Crystal structure of the Zinc finger antiviral protein | | 分子名称: | ZINC ION, Zinc finger CCCH-type antiviral protein 1 | | 著者 | Chen, S, Xu, Y, Zhang, K, Wang, X, Sun, J, Gao, G, Liu, Y. | | 登録日 | 2011-10-18 | | 公開日 | 2012-03-14 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.801 Å) | | 主引用文献 | Structure of N-terminal domain of ZAP indicates how a zinc-finger protein recognizes complex RNA.
Nat.Struct.Mol.Biol., 19, 2012
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3T9K
 | | Crystal Structure of ACAP1 C-portion mutant S554D fused with integrin beta1 peptide | | 分子名称: | Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1,Peptide from Integrin beta-1, SULFATE ION, ... | | 著者 | Sun, F, Pang, X, Zhang, K, Ma, J, Zhou, Q. | | 登録日 | 2011-08-03 | | 公開日 | 2012-07-18 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Mechanistic insights into regulated cargo binding by ACAP1 protein
J.Biol.Chem., 287, 2012
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7N32
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7MWG
 | | 16-nm repeat microtubule doublet | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Rao, Q, Zhang, K. | | 登録日 | 2021-05-17 | | 公開日 | 2021-09-29 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structures of outer-arm dynein array on microtubule doublet reveal a motor coordination mechanism.
Nat.Struct.Mol.Biol., 28, 2021
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7M7E
 | | 6-Deoxyerythronolide B synthase (DEBS) hybrid module (M3/1) in complex with antibody fragment 1B2 | | 分子名称: | 1B2 (heavy chain), 1B2 (light chain), 6-deoxyerythronolide-B synthase EryA2, ... | | 著者 | Cogan, D.P, Zhang, K, Chiu, W, Khosla, C. | | 登録日 | 2021-03-28 | | 公開日 | 2021-11-17 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Mapping the catalytic conformations of an assembly-line polyketide synthase module.
Science, 374, 2021
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7M7H
 | | 6-Deoxyerythronolide B synthase (DEBS) module 1 in complex with antibody fragment 1B2: State 1' | | 分子名称: | 1B2 (heavy chain), 1B2 (light chain), EryAI,6-deoxyerythronolide-B synthase EryA3, ... | | 著者 | Cogan, D.P, Zhang, K, Chiu, W, Khosla, C. | | 登録日 | 2021-03-28 | | 公開日 | 2021-11-17 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Mapping the catalytic conformations of an assembly-line polyketide synthase module.
Science, 374, 2021
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7M7J
 | | 6-Deoxyerythronolide B synthase (DEBS) module 1 in complex with antibody fragment 1B2: "turnstile closed" state (TE-free) | | 分子名称: | 1B2 (heavy chain), 1B2 (light chain), EryAI | | 著者 | Cogan, D.P, Zhang, K, Chiu, W, Khosla, C. | | 登録日 | 2021-03-28 | | 公開日 | 2021-11-17 | | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | | 主引用文献 | Mapping the catalytic conformations of an assembly-line polyketide synthase module.
Science, 374, 2021
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7M7G
 | | 6-Deoxyerythronolide B synthase (DEBS) module 1 in complex with antibody fragment 1B2: State 2 | | 分子名称: | 1B2 (heavy chain), 1B2 (light chain), EryAI,6-deoxyerythronolide-B synthase EryA3, ... | | 著者 | Cogan, D.P, Zhang, K, Chiu, W, Khosla, C. | | 登録日 | 2021-03-28 | | 公開日 | 2021-11-17 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Mapping the catalytic conformations of an assembly-line polyketide synthase module.
Science, 374, 2021
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7M7I
 | | 6-Deoxyerythronolide B synthase (DEBS) module 1 in complex with antibody fragment 1B2 (TE-free) | | 分子名称: | 1B2 (heavy chain), 1B2 (light chain), EryAI, ... | | 著者 | Cogan, D.P, Zhang, K, Chiu, W, Khosla, C. | | 登録日 | 2021-03-28 | | 公開日 | 2021-11-17 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Mapping the catalytic conformations of an assembly-line polyketide synthase module.
Science, 374, 2021
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7M7F
 | | 6-Deoxyerythronolide B synthase (DEBS) module 1 in complex with antibody fragment 1B2: State 1 | | 分子名称: | 1B2 (heavy chain), 1B2 (light chain), EryAI,6-deoxyerythronolide-B synthase EryA3, ... | | 著者 | Cogan, D.P, Zhang, K, Chiu, W, Khosla, C. | | 登録日 | 2021-03-28 | | 公開日 | 2021-11-17 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Mapping the catalytic conformations of an assembly-line polyketide synthase module.
Science, 374, 2021
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7LJY
 | | Cryo-EM structure of the B dENE construct complexed with a 28-mer poly(A) | | 分子名称: | B dENE construct, poly(A) | | 著者 | Torabi, S, Chen, Y, Zhang, K, Wang, J, DeGregorio, S, Vaidya, A, Su, Z, Pabit, S, Chiu, W, Pollack, L, Steitz, J. | | 登録日 | 2021-02-01 | | 公開日 | 2021-04-14 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (5.6 Å) | | 主引用文献 | Structural analyses of an RNA stability element interacting with poly(A).
Proc.Natl.Acad.Sci.USA, 118, 2021
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8JAR
 | | Structure of CRL2APPBP2 bound with RxxGPAA degron (dimer) | | 分子名称: | Amyloid protein-binding protein 2, Cullin-2, Elongin-B, ... | | 著者 | Zhao, S, Zhang, K, Xu, C. | | 登録日 | 2023-05-07 | | 公開日 | 2023-10-18 | | 最終更新日 | 2023-10-25 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Molecular basis for C-degron recognition by CRL2 APPBP2 ubiquitin ligase.
Proc.Natl.Acad.Sci.USA, 120, 2023
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8JAL
 | | Structure of CRL2APPBP2 bound with RxxGP degron (dimer) | | 分子名称: | Amyloid protein-binding protein 2, Cullin-2, Elongin-B, ... | | 著者 | Zhao, S, Zhang, K, Xu, C. | | 登録日 | 2023-05-06 | | 公開日 | 2023-10-18 | | 最終更新日 | 2023-10-25 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Molecular basis for C-degron recognition by CRL2 APPBP2 ubiquitin ligase.
Proc.Natl.Acad.Sci.USA, 120, 2023
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8JAQ
 | | Structure of CRL2APPBP2 bound with RxxGP degron (tetramer) | | 分子名称: | Amyloid protein-binding protein 2, Cullin-2, E3 ubiquitin-protein ligase RBX1, ... | | 著者 | Zhao, S, Zhang, K, Xu, C. | | 登録日 | 2023-05-06 | | 公開日 | 2023-10-18 | | 最終更新日 | 2023-10-25 | | 実験手法 | ELECTRON MICROSCOPY (3.26 Å) | | 主引用文献 | Molecular basis for C-degron recognition by CRL2 APPBP2 ubiquitin ligase.
Proc.Natl.Acad.Sci.USA, 120, 2023
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8JAS
 | | Structure of CRL2APPBP2 bound with RxxGPAA degron (tetramer) | | 分子名称: | Amyloid protein-binding protein 2, Cullin-2, E3 ubiquitin-protein ligase RBX1, ... | | 著者 | Zhao, S, Zhang, K, Xu, C. | | 登録日 | 2023-05-07 | | 公開日 | 2023-10-18 | | 最終更新日 | 2023-10-25 | | 実験手法 | ELECTRON MICROSCOPY (3.54 Å) | | 主引用文献 | Molecular basis for C-degron recognition by CRL2 APPBP2 ubiquitin ligase.
Proc.Natl.Acad.Sci.USA, 120, 2023
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8JAU
 | | Structure of CRL2APPBP2 bound with the C-degron of MRPL28 (dimer) | | 分子名称: | Amyloid protein-binding protein 2, Cullin-2, Elongin-B, ... | | 著者 | Zhao, S, Zhang, K, Xu, C. | | 登録日 | 2023-05-07 | | 公開日 | 2023-10-18 | | 最終更新日 | 2023-10-25 | | 実験手法 | ELECTRON MICROSCOPY (3.22 Å) | | 主引用文献 | Molecular basis for C-degron recognition by CRL2 APPBP2 ubiquitin ligase.
Proc.Natl.Acad.Sci.USA, 120, 2023
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