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6KMV
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BU of 6kmv by Molmil
caspase-11 C254A P22/P10 in complex with mouse GSDMD-C domain
分子名称: Caspase-4, Gasdermin-D
著者Ding, J, Sun, Q.
登録日2019-08-01
公開日2020-03-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.35 Å)
主引用文献Structural Mechanism for GSDMD Targeting by Autoprocessed Caspases in Pyroptosis.
Cell, 180, 2020
3MAW
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BU of 3maw by Molmil
Structure of the Newcastle disease virus F protein in the post-fusion conformation
分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0
著者Jardetzky, T.S, Wen, X.
登録日2010-03-24
公開日2010-05-26
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structure of the Newcastle disease virus F protein in the post-fusion conformation.
Virology, 402, 2010
6KN1
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BU of 6kn1 by Molmil
P20/P12 of caspase-11 mutant C254A
分子名称: Caspase-4
著者Ding, J, Sun, Q.
登録日2019-08-02
公開日2020-03-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural Mechanism for GSDMD Targeting by Autoprocessed Caspases in Pyroptosis.
Cell, 180, 2020
3DNJ
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BU of 3dnj by Molmil
The structure of the Caulobacter crescentus ClpS protease adaptor protein in complex with a N-end rule peptide
分子名称: ATP-dependent Clp protease adapter protein clpS, MAGNESIUM ION, synthetic N-end rule peptide
著者Wang, K, Roman-Hernandez, G, Grant, R.A, Sauer, R.T, Baker, T.A.
登録日2008-07-02
公開日2008-11-18
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献The molecular basis of N-end rule recognition.
Mol.Cell, 32, 2008
7XY4
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BU of 7xy4 by Molmil
Cryo-EM structure of SARS-CoV-2 spike in complex with VHH21
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, VHH21
著者Cao, D, Fan, X, Zhang, X.
登録日2022-05-31
公開日2023-09-13
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Identification of nano-abzymes to catalyze the spike-trimer of SARS-CoV-2
To Be Published
7XY3
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BU of 7xy3 by Molmil
Cryo-EM structure of SARS-CoV-2 spike in complex with VHH14
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, VHH14
著者Cao, D, Fan, X, Zhang, X.
登録日2022-05-31
公開日2023-09-13
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Identification of nano-abzymes to catalyze the spike-trimer of SARS-CoV-2
To Be Published
3SGY
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BU of 3sgy by Molmil
Staphylococcus aureus Dihydrofolate Reductase complexed with NADPH and 6-ETHYL-5-[(3S)-3-[3-METHOXY-5-(PYRIDIN-4-YL)PHENYL]BUT-1-YN-1-YL]PYRIMIDINE-2,4-DIAMINE (UCP1006)
分子名称: 6-ethyl-5-{(3S)-3-[3-methoxy-5-(pyridin-4-yl)phenyl]but-1-yn-1-yl}pyrimidine-2,4-diamine, Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Frey, K.M, Anderson, A.C.
登録日2011-06-15
公開日2012-03-07
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.598 Å)
主引用文献Toward New Therapeutics for Skin and Soft Tissue Infections: Propargyl-Linked Antifolates Are Potent Inhibitors of MRSA and Streptococcus pyogenes.
Plos One, 7, 2012
3SH2
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BU of 3sh2 by Molmil
Staphylococcus aureus Dihydrofolate Reductase complexed with NADPH and 6-ethyl-5-(3-(4-methoxybiphenyl-3-yl)prop-1-ynyl)pyrimidine-2,4-diamine (UCP120J)
分子名称: 6-ethyl-5-[3-(4-methoxybiphenyl-3-yl)prop-1-yn-1-yl]pyrimidine-2,4-diamine, Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Frey, K.M, Anderson, A.C.
登録日2011-06-15
公開日2012-03-07
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.999 Å)
主引用文献Toward New Therapeutics for Skin and Soft Tissue Infections: Propargyl-Linked Antifolates Are Potent Inhibitors of MRSA and Streptococcus pyogenes.
Plos One, 7, 2012
7F70
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BU of 7f70 by Molmil
Crystal structure of Rv3094c
分子名称: Rv3094c
著者Wang, Z.X, Ouyang, S.Y, Zhang, H.T.
登録日2021-06-26
公開日2022-06-29
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Omics analysis of Mycobacterium tuberculosis isolates uncovers Rv3094c, an ethionamide metabolism-associated gene.
Commun Biol, 6, 2023
7F74
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BU of 7f74 by Molmil
Rv3094c in complex with FMN.
分子名称: FLAVIN MONONUCLEOTIDE, Rv3094c
著者Wang, Z.X, Ouyang, S.Y.
登録日2021-06-27
公開日2022-06-29
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Omics analysis of Mycobacterium tuberculosis isolates uncovers Rv3094c, an ethionamide metabolism-associated gene.
Commun Biol, 6, 2023
7F72
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BU of 7f72 by Molmil
Rv3094c in complex with FAD and ETH.
分子名称: 2-ethylpyridine-4-carboximidothioic acid, FLAVIN MONONUCLEOTIDE, Rv3094c
著者Wang, Z.X, Ouyang, S.Y.
登録日2021-06-27
公開日2022-07-13
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Omics analysis of Mycobacterium tuberculosis isolates uncovers Rv3094c, an ethionamide metabolism-associated gene.
Commun Biol, 6, 2023
2HKO
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BU of 2hko by Molmil
Crystal structure of LSD1
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Lysine-specific histone demethylase 1
著者Chen, Y, Yang, Y.T, Wang, F, Yanane, K, Zhang, Y, Lei, M.
登録日2006-07-05
公開日2006-08-29
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of human histone lysine-specific demethylase 1 (LSD1).
Proc.Natl.Acad.Sci.Usa, 103, 2006
4M7C
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BU of 4m7c by Molmil
Crystal structure of the TRF2-binding motif of SLX4 in complex with the TRFH domain of TRF2
分子名称: Peptide from Structure-specific endonuclease subunit SLX4, Telomeric repeat-binding factor 2
著者Wan, B, Chen, Y, Wu, J, Liu, Y, Lei, M.
登録日2013-08-12
公開日2013-09-25
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献SLX4 Assembles a Telomere Maintenance Toolkit by Bridging Multiple Endonucleases with Telomeres
Cell Rep, 4, 2013
4Y7E
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BU of 4y7e by Molmil
Crystal structure of beta-mannanase from Streptomyces thermolilacinus with mannohexaose
分子名称: CALCIUM ION, Endoglucanase, GLYCEROL, ...
著者Kumagai, Y, Yamashita, K, Okuyama, M, Hatanaka, T, Yao, M, Kimura, A.
登録日2015-02-14
公開日2015-09-23
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The loop structure of Actinomycete glycoside hydrolase family 5 mannanases governs substrate recognition
Febs J., 282, 2015
3U84
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BU of 3u84 by Molmil
Crystal Structure of Human Menin
分子名称: Menin
著者Huang, J, Wan, B, Lei, M.
登録日2011-10-15
公開日2012-02-15
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The same pocket in menin binds both MLL and JUND but has opposite effects on transcription.
Nature, 482, 2012
3U86
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BU of 3u86 by Molmil
Crystal structure of human menin in complex with JunD
分子名称: Menin, Transcription factor jun-D
著者Huang, J, Wan, B, Lei, M.
登録日2011-10-15
公開日2012-02-15
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.843 Å)
主引用文献The same pocket in menin binds both MLL and JUND but has opposite effects on transcription.
Nature, 482, 2012
3U85
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BU of 3u85 by Molmil
Crystal structure of human menin in complex with MLL1
分子名称: Histone-lysine N-methyltransferase 2A, Menin
著者Huang, J, Wan, B, Lei, M.
登録日2011-10-15
公開日2012-02-15
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The same pocket in menin binds both MLL and JUND but has opposite effects on transcription.
Nature, 482, 2012
3U88
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BU of 3u88 by Molmil
Crystal structure of human menin in complex with MLL1 and LEDGF
分子名称: (4beta,8alpha,9R)-6'-methoxy-10,11-dihydrocinchonan-9-ol, CHOLIC ACID, GLYOXYLIC ACID, ...
著者Huang, J, Wan, B, Lei, M.
登録日2011-10-16
公開日2012-02-15
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The same pocket in menin binds both MLL and JUND but has opposite effects on transcription.
Nature, 482, 2012
5YAE
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BU of 5yae by Molmil
Ferulic acid esterase from Streptomyces cinnamoneus at 2.4 A resolution
分子名称: ACETATE ION, Esterase, SULFATE ION
著者Tamura, H, Uraji, M, Mizohata, E, Ogawa, K, Inoue, T, Hatanaka, T.
登録日2017-08-31
公開日2017-12-06
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Loop of Streptomyces Feruloyl Esterase Plays an Important Role in the Enzyme's Catalyzing the Release of Ferulic Acid from Biomass.
Appl. Environ. Microbiol., 84, 2018
5YAL
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BU of 5yal by Molmil
Ferulic acid esterase from Streptomyces cinnamoneus at 1.5 A resolution
分子名称: ACETATE ION, Esterase, GLYCEROL, ...
著者Tamura, H, Uraji, M, Mizohata, E, Ogawa, K, Inoue, T, Hatanaka, T.
登録日2017-09-01
公開日2017-12-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Loop of Streptomyces Feruloyl Esterase Plays an Important Role in the Enzyme's Catalyzing the Release of Ferulic Acid from Biomass.
Appl. Environ. Microbiol., 84, 2018
3WSU
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BU of 3wsu by Molmil
Crystal structure of beta-mannanase from Streptomyces thermolilacinus
分子名称: Beta-mannanase, GLYCEROL, SODIUM ION
著者Kumagai, Y, Yamashita, K, Okuyama, M, Hatanaka, T, Yao, M, Kimura, A.
登録日2014-03-26
公開日2015-05-20
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The loop structure of Actinomycete glycoside hydrolase family 5 mannanases governs substrate recognition
Febs J., 282, 2015
6D2L
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BU of 6d2l by Molmil
Crystal structure of human CARM1 with (S)-SKI-72
分子名称: (2S,5S)-2-amino-6-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]-5-[(benzylamino)methyl]-N-[2-(4-hydroxyphenyl)ethyl]hexanamide, GLYCEROL, Histone-arginine methyltransferase CARM1, ...
著者DONG, A, ZENG, H, WALKER, J.R, Hutchinson, A, Seitova, A, LUO, M, CAI, X.C, KE, W, WANG, J, SHI, C, ZHENG, W, LEE, J.P, IBANEZ, G, Bountra, C, Arrowsmith, C.H, Edwards, A.M, BROWN, P.J, WU, H, Structural Genomics Consortium (SGC)
登録日2018-04-13
公開日2018-05-23
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A chemical probe of CARM1 alters epigenetic plasticity against breast cancer cell invasion.
Elife, 8, 2019
8WCT
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BU of 8wct by Molmil
The crystal structure of the CHASE4 domain of iron-sensetive membrane protein (IsmP,Uniprot ID:Q9I243)
分子名称: Bifunctional diguanylate cyclase/phosphodiesterase, GLYCEROL
著者Wang, C.C.
登録日2023-09-13
公開日2024-02-14
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A c-di-GMP signaling module controls responses to iron in Pseudomonas aeruginosa.
Nat Commun, 15, 2024
4IKP
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BU of 4ikp by Molmil
Crystal structure of coactivator-associated arginine methyltransferase 1 with methylenesinefungin
分子名称: (2S,5S)-2,6-diamino-5-{[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl}hexanoic acid, GLYCEROL, Histone-arginine methyltransferase CARM1, ...
著者Dong, A, Dombrovski, L, He, H, Ibanez, G, Wernimont, A, Zheng, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Brown, P.J, Min, J, Luo, M, Wu, H, Structural Genomics Consortium (SGC)
登録日2012-12-27
公開日2013-02-13
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A chemical probe of CARM1 alters epigenetic plasticity against breast cancer cell invasion.
Elife, 8, 2019
7PQX
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BU of 7pqx by Molmil
Structure of CtAtm1 in the inward-facing open conformation
分子名称: Putative iron-sulfur protein
著者Li, P, Wang, K.T, Gourdon, P.E.
登録日2021-09-20
公開日2022-08-10
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (3.08 Å)
主引用文献Structures of Atm1 provide insight into [2Fe-2S] cluster export from mitochondria.
Nat Commun, 13, 2022

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