4KJJ
 
 | | Cryogenic WT DHFR | | 分子名称: | Dihydrofolate reductase, FOLIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | van den Bedem, H, Bhabha, G, Yang, K, Wright, P.E, Fraser, J.S. | | 登録日 | 2013-05-03 | | 公開日 | 2013-08-21 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | | 主引用文献 | Automated identification of functional dynamic contact networks from X-ray crystallography.
Nat.Methods, 10, 2013
|
|
4M6L
 | | Crystal structure of human dihydrofolate reductase (DHFR) bound to NADP+ and 5,10-dideazatetrahydrofolic acid | | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Dihydrofolate reductase, N-(4-{2-[(6S)-2-amino-4-oxo-1,4,5,6,7,8-hexahydropyrido[2,3-d]pyrimidin-6-yl]ethyl}benzoyl)-L-glutamic acid, ... | | 著者 | Bhabha, G, Ekiert, D.C, Wright, P.E, Wilson, I.A. | | 登録日 | 2013-08-09 | | 公開日 | 2013-09-25 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Divergent evolution of protein conformational dynamics in dihydrofolate reductase.
Nat.Struct.Mol.Biol., 20, 2013
|
|
4MWI
 | | Crystal structure of the human MLKL pseudokinase domain | | 分子名称: | (2S)-1-[3-{[(2R)-2-hydroxypropyl]oxy}-2,2-bis({[(2R)-2-hydroxypropyl]oxy}methyl)propoxy]propan-2-ol, GLYCEROL, Mixed lineage kinase domain-like protein | | 著者 | Czabotar, P.E, Murphy, J.M. | | 登録日 | 2013-09-25 | | 公開日 | 2013-12-04 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Insights into the evolution of divergent nucleotide-binding mechanisms among pseudokinases revealed by crystal structures of human and mouse MLKL.
Biochem.J., 457, 2014
|
|
1PRT
 | |
1POU
 | | THE SOLUTION STRUCTURE OF THE OCT-1 POU-SPECIFIC DOMAIN REVEALS A STRIKING SIMILARITY TO THE BACTERIOPHAGE LAMBDA REPRESSOR DNA-BINDING DOMAIN | | 分子名称: | OCT-1 | | 著者 | Assa-Munt, N, Mortishire-Smith, R.J, Aurora, R, Herr, W, Wright, P.E. | | 登録日 | 1993-06-14 | | 公開日 | 1994-10-15 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The solution structure of the Oct-1 POU-specific domain reveals a striking similarity to the bacteriophage lambda repressor DNA-binding domain.
Cell(Cambridge,Mass.), 73, 1993
|
|
1QPD
 | | STRUCTURAL ANALYSIS OF THE LYMPHOCYTE-SPECIFIC KINASE LCK IN COMPLEX WITH NON-SELECTIVE AND SRC FAMILY SELECTIVE KINASE INHIBITORS | | 分子名称: | LCK KINASE, STAUROSPORINE, SULFATE ION | | 著者 | Zhu, X, Kim, J.L, Rose, P.E, Stover, D.R, Toledo, L.M, Zhao, H, Morgenstern, K.A. | | 登録日 | 1999-05-24 | | 公開日 | 2000-05-24 | | 最終更新日 | 2022-12-21 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural analysis of the lymphocyte-specific kinase Lck in complex with non-selective and Src family selective kinase inhibitors.
Structure Fold.Des., 7, 1999
|
|
1NU7
 | | Staphylocoagulase-Thrombin Complex | | 分子名称: | IMIDAZOLE, MERCURY (II) ION, N-(sulfanylacetyl)-D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, ... | | 著者 | Friedrich, R, Bode, W, Fuentes-Prior, P, Panizzi, P, Bock, P.E. | | 登録日 | 2003-01-31 | | 公開日 | 2003-10-07 | | 最終更新日 | 2012-12-12 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Staphylocoagulase is a prototype for the mechanism of cofactor-induced zymogen activation
NATURE, 425, 2003
|
|
1NO8
 | | SOLUTION STRUCTURE OF THE NUCLEAR FACTOR ALY RBD DOMAIN | | 分子名称: | ALY | | 著者 | Perez-Alvarado, G.C, Martinez-Yamout, M, Allen, M.M, Grosschedl, R, Dyson, H.J, Wright, P.E. | | 登録日 | 2003-01-15 | | 公開日 | 2003-08-12 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of the Nuclear Factor ALY: Insights into Post-Transcriptional
Regulatory and mRNA Nuclear Export Processes
Biochemistry, 42, 2003
|
|
1NU9
 | | Staphylocoagulase-Prethrombin-2 complex | | 分子名称: | IMIDAZOLE, MERCURY (II) ION, N-(sulfanylacetyl)-D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, ... | | 著者 | Friedrich, R, Bode, W, Fuentes-Prior, P, Panizzi, P, Bock, P.E. | | 登録日 | 2003-01-31 | | 公開日 | 2003-10-07 | | 最終更新日 | 2012-12-12 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Staphylocoagulase is a prototype for the mechanism of cofactor-induced zymogen activation
NATURE, 425, 2003
|
|
1QPC
 | | STRUCTURAL ANALYSIS OF THE LYMPHOCYTE-SPECIFIC KINASE LCK IN COMPLEX WITH NON-SELECTIVE AND SRC FAMILY SELECTIVE KINASE INHIBITORS | | 分子名称: | 1,2-ETHANEDIOL, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, SULFATE ION, ... | | 著者 | Zhu, X, Kim, J.L, Rose, P.E, Stover, D.R, Toledo, L.M, Zhao, H, Morgenstern, K.A. | | 登録日 | 1999-05-21 | | 公開日 | 2000-05-24 | | 最終更新日 | 2015-08-19 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structural analysis of the lymphocyte-specific kinase Lck in complex with non-selective and Src family selective kinase inhibitors.
Structure Fold.Des., 7, 1999
|
|
1QPJ
 | | CRYSTAL STRUCTURE OF THE LYMPHOCYTE-SPECIFIC KINASE LCK IN COMPLEX WITH STAUROSPORINE. | | 分子名称: | LCK TYROSINE KINASE, STAUROSPORINE, SULFATE ION | | 著者 | Zhu, X, Kim, J.L, Rose, P.E, Stover, D.R, Toledo, L.M. | | 登録日 | 1999-05-25 | | 公開日 | 2000-05-31 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural analysis of the lymphocyte-specific kinase Lck in complex with non-selective and Src family selective kinase inhibitors.
Structure Fold.Des., 7, 1999
|
|
1R8U
 | | NMR structure of CBP TAZ1/CITED2 complex | | 分子名称: | CREB-binding protein, Cbp/p300-interacting transactivator 2, ZINC ION | | 著者 | De Guzman, R.N, Martinez-Yamout, M, Dyson, H.J, Wright, P.E. | | 登録日 | 2003-10-28 | | 公開日 | 2004-03-23 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Interaction of the TAZ1 domain of the CREB-binding protein with the activation domain of CITED2: regulation by competition between intrinsically unstructured ligands for non-identical binding sites.
J.Biol.Chem., 279, 2004
|
|
1R1L
 | | Structure of dimeric antithrombin complexed with a P14-P9 reactive loop peptide and an exogenous tripeptide (formyl-norleucine-LF) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Antithrombin P14-P9 peptide, Antithrombin-III, ... | | 著者 | Zhou, A, Huntington, J.A, Lomas, D.A, Stein, P.E, Carrell, R.W. | | 登録日 | 2003-09-24 | | 公開日 | 2004-10-05 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Serpins and the design of peptides to block intermolecular beta-linkages
To be Published
|
|
1R5E
 | | Solution structure of the folded core of Pseudomonas syringae effector protein, AvrPto | | 分子名称: | avirulence protein | | 著者 | Wulf, J, Pascuzzi, P.E, Martin, G.B, Nicholson, L.K. | | 登録日 | 2003-10-10 | | 公開日 | 2004-10-19 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The solution structure of type III effector protein AvrPto reveals conformational and dynamic features important for plant pathogenesis.
STRUCTURE, 12, 2004
|
|
1RGX
 | | Crystal Structure of resisitin | | 分子名称: | Resistin | | 著者 | Patel, S.D, Rajala, M.W, Scherer, P.E, Shapiro, L, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2003-11-13 | | 公開日 | 2004-06-08 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.787 Å) | | 主引用文献 | Disulfide-dependent multimeric assembly of resistin family hormones
Science, 304, 2004
|
|
2R6X
 | | Structure of a D35N variant PduO-type ATP:co(I)rrinoid adenosyltransferase from Lactobacillus reuteri complexed with ATP | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Cobalamin adenosyltransferase PduO-like protein, MAGNESIUM ION | | 著者 | St Maurice, M, Mera, P.E, Escalante-Semerena, J.C, Rayment, I. | | 登録日 | 2007-09-06 | | 公開日 | 2007-12-18 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | | 主引用文献 | Structural and functional analyses of the human-type corrinoid adenosyltransferase (PduO) from Lactobacillus reuteri.
Biochemistry, 46, 2007
|
|
2R6T
 | | Structure of a R132K variant PduO-type ATP:co(I)rrinoid adenosyltransferase from Lactobacillus reuteri complexed with ATP | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Cobalamin adenosyltransferase PduO-like protein, MAGNESIUM ION | | 著者 | St Maurice, M, Mera, P.E, Escalante-Semerena, J.C, Rayment, I. | | 登録日 | 2007-09-06 | | 公開日 | 2007-12-18 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | | 主引用文献 | Structural and functional analyses of the human-type corrinoid adenosyltransferase (PduO) from Lactobacillus reuteri.
Biochemistry, 46, 2007
|
|
2RLU
 | | The Three Dimensional Structure of the Moorella thermoacetica Selenocysteine Insertion Sequence RNA Hairpin and its Interaction with the Elongation factor SelB | | 分子名称: | RNA (5'-R(*GP*GP*UP*UP*GP*CP*GP*GP*GP*UP*CP*UP*CP*GP*CP*AP*AP*CP*C)-3') | | 著者 | Beribisky, A.V, Tavares, T.J, Amborski, A.N, Motamed, M, Johnson, A.E, Mark, T.L, Johnson, P.E. | | 登録日 | 2007-08-21 | | 公開日 | 2008-02-26 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The three-dimensional structure of the Moorella thermoacetica selenocysteine insertion sequence RNA hairpin and its interaction with the elongation factor SelB
Rna, 13, 2007
|
|
2RPT
 | |
2V7F
 | | Structure of P. abyssi RPS19 protein | | 分子名称: | CHLORIDE ION, RPS19E SSU RIBOSOMAL PROTEIN S19E | | 著者 | Gregory, L.A, Aguissa-Toure, A.H, Pinaud, N, Legrand, P, Gleizes, P.E, Fribourg, S. | | 登録日 | 2007-07-30 | | 公開日 | 2007-09-11 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | | 主引用文献 | Molecular Basis of Diamond Blackfan Anemia: Structure and Function Analysis of Rps19.
Nucleic Acids Res., 35, 2007
|
|
2V94
 | |
2VOG
 | | Structure of mouse A1 bound to the Bmf BH3-domain | | 分子名称: | BCL-2-MODIFYING FACTOR, BCL-2-RELATED PROTEIN A1, CHLORIDE ION | | 著者 | Smits, C, Czabotar, P.E, Hinds, M.G, Day, C.L. | | 登録日 | 2008-02-17 | | 公開日 | 2008-03-04 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural Plasticity Underpins Promiscuous Binding of the Prosurvival Protein A1.
Structure, 16, 2008
|
|
2VOI
 | | Structure of mouse A1 bound to the Bid BH3-domain | | 分子名称: | BCL-2-RELATED PROTEIN A1, BH3-INTERACTING DOMAIN DEATH AGONIST P13, CHLORIDE ION | | 著者 | Smits, C, Czabotar, P.E, Hinds, M.G, Day, C.L. | | 登録日 | 2008-02-17 | | 公開日 | 2008-03-04 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural Plasticity Underpins Promiscuous Binding of the Prosurvival Protein A1.
Structure, 16, 2008
|
|
2VOH
 | | Structure of mouse A1 bound to the Bak BH3-domain | | 分子名称: | BCL-2 HOMOLOGOUS ANTAGONIST/KILLER, BCL-2-RELATED PROTEIN A1, CITRIC ACID, ... | | 著者 | Smits, C, Czabotar, P.E, Hinds, M.G, Day, C.L. | | 登録日 | 2008-02-17 | | 公開日 | 2008-03-04 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural Plasticity Underpins Promiscuous Binding of the Prosurvival Protein A1.
Structure, 16, 2008
|
|
2G9P
 | | NMR structure of a novel antimicrobial peptide, latarcin 2a, from spider (Lachesana tarabaevi) venom | | 分子名称: | antimicrobial peptide Latarcin 2a | | 著者 | Dubovskii, P.V, Volynsky, P.E, Polyansky, A.A, Chupin, V.V, Efremov, R.G, Arseniev, A.S. | | 登録日 | 2006-03-07 | | 公開日 | 2006-09-12 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Spatial structure and activity mechanism of a novel spider antimicrobial peptide.
Biochemistry, 45, 2006
|
|
