2VOH

Structure of mouse A1 bound to the Bak BH3-domain

Summary for 2VOH

Related2VOF 2VOG 2VOI
DescriptorBCL-2-RELATED PROTEIN A1, BCL-2 HOMOLOGOUS ANTAGONIST/KILLER, CITRIC ACID, ... (5 entities in total)
Functional Keywordsbh3, bcl-2, membrane, apoptosis, pro-survival, transmembrane, protein-protein complex
Biological sourceMUS MUSCULUS (MOUSE)
Cellular locationCytoplasm Q07440
Mitochondrion membrane; Single-pass membrane protein (Potential) O08734
Total number of polymer chains2
Total molecular weight21127.82
Authors
Smits, C.,Czabotar, P.E.,Hinds, M.G.,Day, C.L. (deposition date: 2008-02-17, release date: 2008-03-04, Last modification date: 2011-07-13)
Primary citation
Smits, C.,Czabotar, P.E.,Hinds, M.G.,Day, C.L.
Structural Plasticity Underpins Promiscuous Binding of the Prosurvival Protein A1.
Structure, 16:818-, 2008
PubMed: 18462686 (PDB entries with the same primary citation)
DOI: 10.1016/J.STR.2008.02.009
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.9 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.233402.6%3.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 2voh
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Molmil generated image of 2voh
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Molmil generated image of 2voh
rotated about y axis by 90°