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2VOH

Structure of mouse A1 bound to the Bak BH3-domain

Functional Information from GO Data
ChainGOidnamespacecontents
A0042981biological_processregulation of apoptotic process
A0043066biological_processnegative regulation of apoptotic process
B0042981biological_processregulation of apoptotic process
Functional Information from PDB Data
site_idAC1
Number of Residues8
DetailsBINDING SITE FOR RESIDUE SO4 B1088
ChainResidue
APHE42
ALYS46
ALYS77
BASN65
BSER66
BGLY69
BARG73
BHOH2007

site_idAC2
Number of Residues8
DetailsBINDING SITE FOR RESIDUE CIT A1151
ChainResidue
AHIS8
AGLY138
AGLY139
ATRP140
AGLU141
AASP142
AHOH2097
AGLU5

Functional Information from PROSITE/UniProt
site_idPS01259
Number of Residues15
DetailsBH3 Apoptosis regulator, Bcl-2 family BH3 motif signature. VgrqLAlIGDDINRR
ChainResidueDetails
BVAL71-ARG85

site_idPS01080
Number of Residues20
DetailsBH1 Apoptosis regulator, Bcl-2 family BH1 motif signature. EFeDGiiNWGRIVTIFaFGG
ChainResidueDetails
AGLU78-GLY97

site_idPS01258
Number of Residues12
DetailsBH2 Apoptosis regulator, Bcl-2 family BH2 motif signature. WIrqnGGWEdGF
ChainResidueDetails
ATRP133-PHE144

218853

PDB entries from 2024-04-24

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