2VOF

Structure of mouse A1 bound to the Puma BH3-domain

Summary for 2VOF

Related2VOG 2VOH 2VOI
DescriptorBCL-2-RELATED PROTEIN A1, BCL-2-BINDING COMPONENT 3, CHLORIDE ION, ... (4 entities in total)
Functional Keywordsbh3, bcl-2, apoptosis, pro-survival, mitochondrion, protein-protein complex
Biological sourceMUS MUSCULUS (MOUSE)
Cellular locationCytoplasm Q07440
Mitochondrion Q99ML1
Total number of polymer chains4
Total molecular weight42677.84
Authors
Smits, C.,Czabotar, P.E.,Hinds, M.G.,Day, C.L. (deposition date: 2008-02-17, release date: 2008-03-04, Last modification date: 2011-07-13)
Primary citation
Smits, C.,Czabotar, P.E.,Hinds, M.G.,Day, C.L.
Structural Plasticity Underpins Promiscuous Binding of the Prosurvival Protein A1.
Structure, 16:818-, 2008
PubMed: 18462686 (PDB entries with the same primary citation)
DOI: 10.1016/J.STR.2008.02.009
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.8 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliers0.221301.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 2vof
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Molmil generated image of 2vof
rotated about x axis by 90°
Molmil generated image of 2vof
rotated about y axis by 90°