2VOF
Structure of mouse A1 bound to the Puma BH3-domain
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C | BCL-2-RELATED PROTEIN A1 | polymer | 157 | 18110.0 | 2 | UniProt (Q07440) Pfam (PF00452) In PDB | MUS MUSCULUS (MOUSE) | PROTEIN BFL-1, HEMOPOIETIC-SPECIFIC EARLY RESPONSE PROTEIN, A1-A |
2 | B, D | BCL-2-BINDING COMPONENT 3 | polymer | 26 | 3193.5 | 2 | UniProt (Q99ML1) In PDB | MUS MUSCULUS (MOUSE) | P53 UP-REGULATED MODULATOR OF APOPTOSIS |
3 | A, C | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
4 | water | water | 18.0 | 176 | Chemie (HOH) |
Sequence modifications
A, C: -4 - 0 (PDB: 2VOF)
A, C: 1 - 152 (UniProt: Q07440)
B, D: 130 - 155 (UniProt: Q99ML1)
A, C: 1 - 152 (UniProt: Q07440)
PDB | External Database | Details |
---|---|---|
Lys 104 | Pro 104 | engineered mutation |
Ser 113 | Cys 113 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Ile 144 | Met 144 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 42606.9 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 70.9 | |
All* | Total formula weight | 42677.8 |