2VOI

Structure of mouse A1 bound to the Bid BH3-domain

Summary for 2VOI

Related2VOF 2VOG 2VOH
DescriptorBCL-2-RELATED PROTEIN A1, BH3-INTERACTING DOMAIN DEATH AGONIST P13, CHLORIDE ION, ... (4 entities in total)
Functional Keywordsprotein-protein complex, bh3, bcl-2, membrane, apoptosis, pro-survival, mitochondrion, phosphoprotein
Biological sourceMUS MUSCULUS (MOUSE)
Cellular locationCytoplasm Q07440 P70444
Total number of polymer chains2
Total molecular weight21899.24
Authors
Smits, C.,Czabotar, P.E.,Hinds, M.G.,Day, C.L. (deposition date: 2008-02-17, release date: 2008-03-04, Last modification date: 2011-07-13)
Primary citation
Smits, C.,Czabotar, P.E.,Hinds, M.G.,Day, C.L.
Structural Plasticity Underpins Promiscuous Binding of the Prosurvival Protein A1.
Structure, 16:818-, 2008
PubMed: 18462686 (PDB entries with the same primary citation)
DOI: 10.1016/J.STR.2008.02.009
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.1 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.24901.8%6.9%15.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 2voi
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Molmil generated image of 2voi
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Molmil generated image of 2voi
rotated about y axis by 90°