1QPD
STRUCTURAL ANALYSIS OF THE LYMPHOCYTE-SPECIFIC KINASE LCK IN COMPLEX WITH NON-SELECTIVE AND SRC FAMILY SELECTIVE KINASE INHIBITORS
Summary for 1QPD
Entry DOI | 10.2210/pdb1qpd/pdb |
Related | 1QPC 1QPE 1QPJ |
Descriptor | LCK KINASE, SULFATE ION, STAUROSPORINE, ... (4 entities in total) |
Functional Keywords | alpha beta fold, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P06239 |
Total number of polymer chains | 1 |
Total formula weight | 32739.26 |
Authors | Zhu, X.,Kim, J.L.,Rose, P.E.,Stover, D.R.,Toledo, L.M.,Zhao, H.,Morgenstern, K.A. (deposition date: 1999-05-24, release date: 2000-05-24, Last modification date: 2022-12-21) |
Primary citation | Zhu, X.,Kim, J.L.,Newcomb, J.R.,Rose, P.E.,Stover, D.R.,Toledo, L.M.,Zhao, H.,Morgenstern, K.A. Structural analysis of the lymphocyte-specific kinase Lck in complex with non-selective and Src family selective kinase inhibitors. Structure Fold.Des., 7:651-661, 1999 Cited by PubMed: 10404594DOI: 10.1016/S0969-2126(99)80086-0 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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