6MHU
 
 | | Nucleotide-free Cryo-EM Structure of E.coli LptB2FG Transporter | | 分子名称: | (2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-2-[(2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-5-[(2~{S},3~{S},4~{R},5~{R},6~{R})-6-[(1~{S})-1,2-bis(oxidanyl)ethyl]-4-[(2~{R},3~{S},4~{R},5~{S},6~{R})-6-[(1~{S})-2-[(2~{S},3~{S},4~{S},5~{S},6~{R})-6-[(1~{S})-1,2-bis(oxidanyl)ethyl]-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-1-oxidanyl-ethyl]-3,4-bis(oxidanyl)-5-phosphonooxy-oxan-2-yl]oxy-3-oxidanyl-5-phosphonooxy-oxan-2-yl]oxy-2-carboxy-2-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-5-[[(3~{R})-3-dodecanoyloxytetradecanoyl]amino]-6-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-3-oxidanyl-5-[[(3~{R})-3-oxidanyltetradecanoyl]amino]-4-[(3~{R})-3-oxidanyltetradecanoyl]oxy-6-phosphonooxy-oxan-2-yl]methoxy]-3-phosphonooxy-4-[(3~{R})-3-tetradecanoyloxytetradecanoyl]oxy-oxan-2-yl]methoxy]oxan-4-yl]oxy-4,5-bis(oxidanyl)oxane-2-carboxylic acid, Lipopolysaccharide export system ATP-binding protein LptB, Lipopolysaccharide export system permease protein LptF, ... | | 著者 | Orlando, B.J, Li, Y, Liao, M. | | 登録日 | 2018-09-18 | | 公開日 | 2019-04-03 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Structural basis of lipopolysaccharide extraction by the LptB2FGC complex.
Nature, 567, 2019
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6MI8
 | | Cryo-EM Structure of vanadate-trapped E.coli LptB2FGC | | 分子名称: | ADP ORTHOVANADATE, Lipopolysaccharide export system ATP-binding protein LptB, Lipopolysaccharide export system permease protein LptF, ... | | 著者 | Orlando, B.J, Li, Y, Liao, M. | | 登録日 | 2018-09-19 | | 公開日 | 2019-04-03 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | | 主引用文献 | Structural basis of lipopolysaccharide extraction by the LptB2FGC complex.
Nature, 567, 2019
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3QUY
 | | Structure of the mouse CD1d-BnNH-GSL-1'-iNKT TCR complex | | 分子名称: | (2S,3R,4S,5R,6S)-6-[(2S,3S,4R)-2-(hexacosanoylamino)-3,4-dihydroxy-octadecoxy]-3,4,5-trihydroxy-N-(phenylmethyl)oxane-2-carboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Li, Y, Girardi, E, Yu, E.D, Zajonc, D.M. | | 登録日 | 2011-02-24 | | 公開日 | 2011-06-29 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Galactose-modified iNKT cell agonists stabilized by an induced fit of CD1d prevent tumour metastasis.
Embo J., 30, 2011
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6MHZ
 | | Vanadate trapped Cryo-EM Structure of E.coli LptB2FG Transporter | | 分子名称: | ADP ORTHOVANADATE, Lipopolysaccharide export system ATP-binding protein LptB, Lipopolysaccharide export system permease protein LptF, ... | | 著者 | Orlando, B.J, Li, Y, Liao, M. | | 登録日 | 2018-09-18 | | 公開日 | 2019-04-03 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Structural basis of lipopolysaccharide extraction by the LptB2FGC complex.
Nature, 567, 2019
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6MI7
 | | Nucleotide-free Cryo-EM Structure of E.coli LptB2FGC | | 分子名称: | (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, Lipopolysaccharide export system ATP-binding protein LptB, Lipopolysaccharide export system permease protein LptF, ... | | 著者 | Orlando, B.J, Li, Y, Liao, M. | | 登録日 | 2018-09-19 | | 公開日 | 2019-04-03 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Structural basis of lipopolysaccharide extraction by the LptB2FGC complex.
Nature, 567, 2019
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6M62
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3QUX
 | | Structure of the mouse CD1d-alpha-C-GalCer-iNKT TCR complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ... | | 著者 | Li, Y, Girardi, E, Yu, E.D, Zajonc, D.M. | | 登録日 | 2011-02-24 | | 公開日 | 2011-06-29 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.91 Å) | | 主引用文献 | Galactose-modified iNKT cell agonists stabilized by an induced fit of CD1d prevent tumour metastasis.
Embo J., 30, 2011
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4IS6
 | | Crystal structure of HLA-DR4 bound to GP100 peptide | | 分子名称: | HLA class II histocompatibility antigen, DR alpha chain, DRB1-4 beta chain, ... | | 著者 | Li, Y. | | 登録日 | 2013-01-16 | | 公開日 | 2013-10-23 | | 最終更新日 | 2013-11-20 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure-Based Design of Altered MHC Class II-Restricted Peptide Ligands with Heterogeneous Immunogenicity.
J.Immunol., 191, 2013
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5V4B
 | | Crystal structure of the Skp1-FBXW7-DISC1 complex | | 分子名称: | DISC1 peptide, F-box/WD repeat-containing protein 7, IMIDAZOLE, ... | | 著者 | Li, Y, Baillie, G.S, Hao, B. | | 登録日 | 2017-03-08 | | 公開日 | 2017-09-20 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | FBXW7 regulates DISC1 stability via the ubiquitin-proteosome system.
Mol. Psychiatry, 23, 2018
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5W2J
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7F3B
 | | cocrystallization of Escherichia coli dihydrofolate reductase (DHFR) and its pyrrolo[3,2-f]quinazoline inhibitor. | | 分子名称: | 7-[(2-fluorophenyl)methyl]pyrrolo[3,2-f]quinazoline-1,3-diamine, Dihydrofolate reductase, GLYCEROL | | 著者 | Wang, H, You, X.F, Yang, X.Y, Li, Y, Hong, W. | | 登録日 | 2021-06-16 | | 公開日 | 2022-04-27 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | | 主引用文献 | The discovery of 1, 3-diamino-7H-pyrrol[3, 2-f]quinazoline compounds as potent antimicrobial antifolates.
Eur.J.Med.Chem., 228, 2022
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4P7I
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4R9V
 | | Crystal structure of sialyltransferase from photobacterium damselae, residues 113-497 corresponding to the gt-b domain | | 分子名称: | CALCIUM ION, Sialyltransferase 0160 | | 著者 | Li, Y, Huynh, N, Chen, X, Fisher, A.J. | | 登録日 | 2014-09-08 | | 公開日 | 2014-12-03 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structures of sialyltransferase from Photobacterium damselae.
Febs Lett., 588, 2014
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8JYZ
 | | Cryo-EM structure of RCD-1 pore from Neurospora crassa | | 分子名称: | Gasdermin-like protein rcd-1-1, Gasdermin-like protein rcd-1-2 | | 著者 | Hou, Y.J, Sun, Q, Li, Y, Ding, J. | | 登録日 | 2023-07-04 | | 公開日 | 2024-05-01 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.63 Å) | | 主引用文献 | Cleavage-independent activation of ancient eukaryotic gasdermins and structural mechanisms.
Science, 384, 2024
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5Y27
 | | Crystal structure of Se-Met Dpb4-Dpb3 | | 分子名称: | DNA polymerase epsilon subunit D, GLYCEROL, Putative transcription factor C16C4.22 | | 著者 | Li, Y, Gao, F, Su, M, Zhang, F.B, Chen, Y.H. | | 登録日 | 2017-07-24 | | 公開日 | 2018-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Coordinated regulation of heterochromatin inheritance by Dpb3-Dpb4 complex.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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8GJX
 | | Structure of the human STING receptor bound to 2'3'-cUA | | 分子名称: | 2'3'-cUA, Stimulator of interferon genes protein | | 著者 | Morehouse, B.R, Li, Y, Slavik, K.M, Toyoda, H, Kranzusch, P.J. | | 登録日 | 2023-03-16 | | 公開日 | 2023-07-05 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | cGLRs are a diverse family of pattern recognition receptors in innate immunity.
Cell, 186, 2023
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7E74
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7X8B
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7X8F
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7X8G
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7W6A
 | | Crystal structure of the MLL1 (N3861I/Q3867L/C3882SS)-RBBP5-ASH2L complex | | 分子名称: | Histone-lysine N-methyltransferase 2A, Retinoblastoma-binding protein 5, S-ADENOSYL-L-HOMOCYSTEINE, ... | | 著者 | Zhao, L, Li, Y, Chen, Y. | | 登録日 | 2021-12-01 | | 公開日 | 2022-09-07 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | | 主引用文献 | Structural basis for product specificities of MLL family methyltransferases.
Mol.Cell, 82, 2022
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7W6I
 | | The crystal structure of MLL1 (N3861I/Q3867L/C3882SS)-RBBP5-ASH2L in complex with H3K4me1 peptide | | 分子名称: | Histone H3.3C, Histone-lysine N-methyltransferase 2A, Retinoblastoma-binding protein 5, ... | | 著者 | Zhao, L, Li, Y, Chen, Y. | | 登録日 | 2021-12-01 | | 公開日 | 2022-09-07 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.56 Å) | | 主引用文献 | Structural basis for product specificities of MLL family methyltransferases.
Mol.Cell, 82, 2022
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7W6L
 | | The crystal structure of MLL3-RBBP5-ASH2L in complex with H3K4me0 peptide | | 分子名称: | Histone H3.3C, Histone-lysine N-methyltransferase 2C, Retinoblastoma-binding protein 5, ... | | 著者 | Zhao, L, Li, Y, Chen, Y. | | 登録日 | 2021-12-01 | | 公開日 | 2022-09-07 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | | 主引用文献 | Structural basis for product specificities of MLL family methyltransferases.
Mol.Cell, 82, 2022
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7W67
 | | The crystal structure of MLL1 (N3861I/Q3867L/C3882SS)-RBBP5-ASH2L in complex with H3K4me0 peptide | | 分子名称: | Histone H3.3C, Histone-lysine N-methyltransferase 2A, Retinoblastoma-binding protein 5, ... | | 著者 | Zhao, L, Li, Y, Chen, Y. | | 登録日 | 2021-12-01 | | 公開日 | 2022-09-07 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.194 Å) | | 主引用文献 | Structural basis for product specificities of MLL family methyltransferases.
Mol.Cell, 82, 2022
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7W6J
 | | The crystal structure of MLL1 (N3861I/Q3867L/C3882SS)-RBBP5-ASH2L in complex with H3K4me2 peptide | | 分子名称: | Histone H3.3C, Histone-lysine N-methyltransferase 2A, Retinoblastoma-binding protein 5, ... | | 著者 | Zhao, L, Li, Y, Chen, Y. | | 登録日 | 2021-12-01 | | 公開日 | 2022-09-07 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | | 主引用文献 | Structural basis for product specificities of MLL family methyltransferases.
Mol.Cell, 82, 2022
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