6WEX
 
 | | Crystal Structure of Broadly Neutralizing Antibody 3I14-D93N Mutant Bound to the Influenza A H6 Hemagglutinin | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, Hemagglutinin HA2 chain, ... | | 著者 | Harshbarger, W.D, Lockbaum, G.J, Deming, D.T, Attatippaholkun, N, Schiffer, C.A, Marasco, W.A. | | 登録日 | 2020-04-03 | | 公開日 | 2020-11-25 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.49 Å) | | 主引用文献 | Unique structural solution from a V H 3-30 antibody targeting the hemagglutinin stem of influenza A viruses.
Nat Commun, 12, 2021
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6WMA
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6WMC
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6WF0
 | | Crystal Structure of Broadly Neutralizing Antibody 3I14 Bound to the Influenza A H3 Hemagglutinin | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Harshbarger, W.D, Lockbaum, G.J, Deming, D.T, Attatippaholkun, N, Schiffer, C.A, Marasco, W.A. | | 登録日 | 2020-04-03 | | 公開日 | 2020-11-25 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (3.46 Å) | | 主引用文献 | Unique structural solution from a V H 3-30 antibody targeting the hemagglutinin stem of influenza A viruses.
Nat Commun, 12, 2021
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6WF1
 | | Crystal Structure of Broadly Neutralizing Antibody 3I14 Bound to the Influenza A H10 Hemagglutinin | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, Hemagglutinin HA2 chain, ... | | 著者 | Harshbarger, W.D, Lockbaum, G.J, Deming, D.T, Attatippaholkun, N, Schiffer, C.A, Marasco, W.A. | | 登録日 | 2020-04-03 | | 公開日 | 2020-11-25 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (4.19 Å) | | 主引用文献 | Unique structural solution from a V H 3-30 antibody targeting the hemagglutinin stem of influenza A viruses.
Nat Commun, 12, 2021
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6WMB
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6WEZ
 | | Crystal Structure of Broadly Neutralizing Antibody 3I14-D93N Mutant Bound to the Influenza A H3 Hemagglutinin | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Hemagglutinin, ... | | 著者 | Harshbarger, W.D, Lockbaum, G.J, Deming, D.T, Attatippaholkun, N, Schiffer, C.A, Marasco, W.A. | | 登録日 | 2020-04-03 | | 公開日 | 2020-11-25 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (3.21 Å) | | 主引用文献 | Unique structural solution from a V H 3-30 antibody targeting the hemagglutinin stem of influenza A viruses.
Nat Commun, 12, 2021
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4G3Y
 | | Crystal structure of TNF-alpha in complex with Infliximab Fab fragment | | 分子名称: | Tumor necrosis factor, infliximab Fab H, infliximab Fab L | | 著者 | Liang, S.Y, Dai, J.X, Guo, Y.J, Lou, Z.Y. | | 登録日 | 2012-07-15 | | 公開日 | 2013-03-27 | | 最終更新日 | 2013-08-07 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural basis for treating tumor necrosis factor alpha (TNFalpha)-associated diseases with the therapeutic antibody infliximab
J.Biol.Chem., 288, 2013
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4JDN
 | | Secreted Chlamydial Protein PGP3, C-terminal Domain | | 分子名称: | GLYCEROL, POTASSIUM ION, Virulence plasmid protein pGP3-D | | 著者 | Galaleldeen, A, Taylor, A.B, Chen, D, Holloway, S.P, Zhong, G, Hart, P.J. | | 登録日 | 2013-02-25 | | 公開日 | 2013-06-05 | | 最終更新日 | 2013-10-09 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure of the Chlamydia trachomatis immunodominant antigen Pgp3.
J.Biol.Chem., 288, 2013
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4JDM
 | | Secreted Chlamydial Protein PGP3, full-length | | 分子名称: | Virulence plasmid protein pGP3-D | | 著者 | Galaleldeen, A, Taylor, A.B, Chen, D, Holloway, S.P, Zhong, G, Hart, P.J. | | 登録日 | 2013-02-25 | | 公開日 | 2013-06-05 | | 最終更新日 | 2013-10-09 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structure of the Chlamydia trachomatis immunodominant antigen Pgp3.
J.Biol.Chem., 288, 2013
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3BKY
 | | Crystal Structure of Chimeric Antibody C2H7 Fab in complex with a CD20 Peptide | | 分子名称: | B-lymphocyte antigen CD20, the Fab fragment of chimeric 2H7, heavy chain, ... | | 著者 | Du, J, Zhong, C, Ding, J. | | 登録日 | 2007-12-07 | | 公開日 | 2008-04-29 | | 最終更新日 | 2024-04-10 | | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | | 主引用文献 | Crystal structure of chimeric antibody C2H7 Fab in complex with a CD20 peptide
Mol.Immunol., 45, 2008
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3WD5
 | | Crystal structure of TNFalpha in complex with Adalimumab Fab fragment | | 分子名称: | Adalimumab Heavy Chain, Adalimumab Light Chain, Tumor necrosis factor | | 著者 | Hu, S, Liang, S.Y, Guo, Y.J, Lou, Z.Y. | | 登録日 | 2013-06-06 | | 公開日 | 2013-08-14 | | 最終更新日 | 2015-07-01 | | 実験手法 | X-RAY DIFFRACTION (3.101 Å) | | 主引用文献 | Comparison of the inhibition mechanisms of adalimumab and infliximab in treating tumor necrosis factor alpha-associated diseases from a molecular view
J.Biol.Chem., 288, 2013
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3WLW
 | | Molecular Architecture of the ErbB2 Extracellular Domain Homodimer | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody H Chain, ... | | 著者 | Hu, S, Lou, Z.Y, Guo, Y.J. | | 登録日 | 2013-11-15 | | 公開日 | 2015-05-27 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (3.088 Å) | | 主引用文献 | Molecular architecture of the ErbB2 extracellular domain homodimer.
Oncotarget, 6, 2015
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3EOB
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3EOA
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3EO9
 | | Crystal structure the Fab fragment of Efalizumab | | 分子名称: | Efalizumab Fab fragment, heavy chain, light chain | | 著者 | Li, S, Ding, J. | | 登録日 | 2008-09-26 | | 公開日 | 2009-04-14 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Efalizumab binding to the LFA-1 alphaL I domain blocks ICAM-1 binding via steric hindrance.
Proc.Natl.Acad.Sci.USA, 106, 2009
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7F65
 | | Bacetrial Cocaine Esterase with mutations T172R/G173Q/V116K/S117A/A51L, bound to benzoic acid | | 分子名称: | BENZOIC ACID, Cocaine esterase, SULFATE ION | | 著者 | Ouyang, P.F, Zhang, Y, Tong, J. | | 登録日 | 2021-06-24 | | 公開日 | 2021-09-15 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.202 Å) | | 主引用文献 | Computational Design and Crystal Structure of a Highly Efficient Benzoylecgonine Hydrolase.
Angew.Chem.Int.Ed.Engl., 60, 2021
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3CXD
 | | Crystal structure of anti-osteopontin antibody 23C3 in complex with its epitope peptide | | 分子名称: | Fab fragment of anti-osteopontin antibody 23C3, Heavy chain, Light chain, ... | | 著者 | Du, J, Yang, H, Zhong, C, Ding, J. | | 登録日 | 2008-04-24 | | 公開日 | 2008-10-14 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Molecular basis of recognition of human osteopontin by 23C3, a potential therapeutic antibody for treatment of rheumatoid arthritis
J.Mol.Biol., 382, 2008
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3DSF
 | | Crystal structure of anti-osteopontin antibody 23C3 in complex with W43A mutated epitope peptide | | 分子名称: | Fab fragment of anti-osteopontin antibody 23C3, Heavy chain, Light chain, ... | | 著者 | Du, J, Zhong, C, Yang, H, Ding, J. | | 登録日 | 2008-07-12 | | 公開日 | 2008-10-14 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Molecular basis of recognition of human osteopontin by 23C3, a potential therapeutic antibody for treatment of rheumatoid arthritis
J.Mol.Biol., 382, 2008
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5VGC
 | | Crystal structure of the NleG5-1 effector (C200A) from Escherichia coli O157:H7 str. Sakai | | 分子名称: | CALCIUM ION, CHLORIDE ION, GLYCEROL, ... | | 著者 | Borek, D, Valleau, D, Skarina, T, Jobin, M.C, Wawrzak, Z, Anderson, W.F, Savchenko, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2017-04-10 | | 公開日 | 2018-04-18 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal structure of the NleG5-1 effector (C200A) from Escherichia coli O157:H7 str. Sakai
To Be Published
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4JDO
 | | Secreted chlamydial protein pgp3, coiled-coil deletion | | 分子名称: | SODIUM ION, Virulence plasmid protein pGP3-D | | 著者 | Galaleldeen, A, Taylor, A.B, Chen, D, Holloway, S.P, Zhong, G, Hart, P.J. | | 登録日 | 2013-02-25 | | 公開日 | 2013-06-05 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure of the Chlamydia trachomatis immunodominant antigen Pgp3.
J.Biol.Chem., 288, 2013
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8JBJ
 | | Crystal structure of anti-PVRIG Fab | | 分子名称: | antibody heavy chain, antibody light chain | | 著者 | Sun, J, Li, X.L, Song, J. | | 登録日 | 2023-05-09 | | 公開日 | 2023-06-21 | | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | | 主引用文献 | Identification and characterization of an unexpected isomerization motif in CDRH2 that affects antibody activity.
Mabs, 15, 2023
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4P08
 | | Engineered thermostable dimeric cocaine esterase | | 分子名称: | Cocaine esterase | | 著者 | Rodgers, D.W, Chow, K.-M, Fang, L, Zhan, C.-G. | | 登録日 | 2014-02-20 | | 公開日 | 2014-07-16 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.341 Å) | | 主引用文献 | Rational design, preparation, and characterization of a therapeutic enzyme mutant with improved stability and function for cocaine detoxification.
Acs Chem.Biol., 9, 2014
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2FO3
 | | Plasmodium vivax ubiquitin conjugating enzyme E2 | | 分子名称: | Ubiquitin-conjugating enzyme | | 著者 | Dong, A, Zhao, Y, Lew, J, Kozieradski, I, Alam, Z, Melone, M, Wasney, G, Vedadi, M, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Hui, R, Bochkarev, A, Qiu, W, Structural Genomics Consortium (SGC) | | 登録日 | 2006-01-12 | | 公開日 | 2006-01-31 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms.
Mol.Biochem.Parasitol., 151, 2007
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2FU0
 | | Plasmodium falciparum cyclophilin PFE0505w putative cyclosporin-binding domain | | 分子名称: | cyclophilin, putative | | 著者 | Dong, A, Lew, J, Sundararajan, E, Zhao, Y, Wasney, G, Vedadi, M, Koeieradzki, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Bochkarev, A, Hui, R, Hills, T, Structural Genomics Consortium (SGC) | | 登録日 | 2006-01-25 | | 公開日 | 2006-02-07 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms.
Mol.Biochem.Parasitol., 151, 2007
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