6WMA

Crystal structure of a soluble variant of full-length human APOBEC3G (pH 7.6)

Summary for 6WMA

• Entry DOI: 10.2210/pdb6wma/pdb
• Descriptor: APOLIPOPROTEIN B MRNA EDITING ENZYME, CATALYTIC PEPTIDE- LIKE 3G, DNA (5'-D(P*CP*C)-3'), ZINC ION, ... (6 entities in total)
• Functional Keywords: apobec3g, antiviral defense, hydrolase, dna cytidine deaminase, hydrolase-dna complex, hydrolase/dna
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 43194.08

Authors

Maiti, A.,Matsuo, H. (deposition date: 2020-04-21, release date: 2020-12-23, Last modification date: 2023-10-18)

• Primary citation: Maiti, A.,Myint, W.,Delviks-Frankenberry, K.A.,Hou, S.,Kanai, T.,Balachandran, V.,Sierra Rodriguez, C.,Tripathi, R.,Kurt Yilmaz, N.,Pathak, V.K.,Schiffer, C.A.,Matsuo, H.; Crystal Structure of a Soluble APOBEC3G Variant Suggests ssDNA to Bind in a Channel that Extends between the Two Domains.; J.Mol.Biol., 432:6042-6060, 2020; PubMed: 33098858; DOI: 10.1016/j.jmb.2020.10.020

Experimental method

X-RAY DIFFRACTION (2.5 Å)