8T7C
 
 | | Crystal structure of human phospholipase C gamma 2 | | 分子名称: | 1,2-ETHANEDIOL, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2, CALCIUM ION | | 著者 | Chen, Y, Choi, H, Zhuang, N, Hu, L, Qian, D, Wang, J. | | 登録日 | 2023-06-20 | | 公開日 | 2024-06-26 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | The crystal and cryo-EM structures of PLCg2 reveal dynamic inter-domain recognitions in autoinhibition
To Be Published
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8F93
 | | WDR5 covalently modified at Y228 by (R)-2-SF | | 分子名称: | 3-ethynyl-5-{[(3R)-4-{1-[(2-methoxyphenyl)methyl]-1H-benzimidazole-5-carbonyl}-3-methylpiperazin-1-yl]methyl}benzene-1-sulfonyl fluoride, CHLORIDE ION, GLYCEROL, ... | | 著者 | Taunton, J, Craven, G.B, Chen, Y. | | 登録日 | 2022-11-23 | | 公開日 | 2023-05-31 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Direct mapping of ligandable tyrosines and lysines in cells with chiral sulfonyl fluoride probes.
Nat.Chem., 15, 2023
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8G6U
 | | Cryo-EM structure of T/F100 SOSIP.664 HIV-1 Env trimer with LMHS mutations in complex with 8ANC195 and 10-1074 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CRF-1_AE T/F100 HIV-1 gp41, ... | | 著者 | Chen, Y, Zhou, F, Huang, R, Tolbert, W, Pazgier, M. | | 登録日 | 2023-02-16 | | 公開日 | 2023-11-08 | | 実験手法 | ELECTRON MICROSCOPY (3.16 Å) | | 主引用文献 | Structure-function analyses reveal key molecular determinants of HIV-1 CRF01_AE resistance to the entry inhibitor temsavir.
Nat Commun, 14, 2023
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2N7X
 | | Solution structure of microRNA 20b pre-element | | 分子名称: | RNA (5'-R(*GP*GP*UP*AP*GP*UP*UP*UP*UP*GP*GP*CP*AP*UP*GP*AP*CP*UP*CP*UP*AP*CP*C)-3') | | 著者 | Yang, F, Chen, Y, Varani, G. | | 登録日 | 2015-09-25 | | 公開日 | 2016-04-13 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Rbfox proteins regulate microRNA biogenesis by sequence-specific binding to their precursors and target downstream Dicer.
Nucleic Acids Res., 44, 2016
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2N82
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8KAG
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8KAK
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8KAJ
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8KAH
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8KAI
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8KAM
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8KAL
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7EQT
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7EQS
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7EQW
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7ER1
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7ER0
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8J54
 | | Crystal structure of RXR/DR2 complex | | 分子名称: | DNA (5'-D(*CP*AP*TP*GP*AP*CP*CP*TP*AP*CP*TP*GP*AP*CP*CP*TP*AP*G)-3'), DNA (5'-D(*CP*TP*AP*GP*GP*TP*CP*AP*GP*TP*AP*GP*GP*TP*CP*AP*TP*G)-3'), Retinoic acid receptor RXR, ... | | 著者 | Chen, Y, Jiang, L. | | 登録日 | 2023-04-21 | | 公開日 | 2024-01-17 | | 最終更新日 | 2024-04-17 | | 実験手法 | X-RAY DIFFRACTION (2.72 Å) | | 主引用文献 | Structural characterization of the DNA binding mechanism of retinoic acid-related orphan receptor gamma.
Structure, 32, 2024
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8KGO
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5YC2
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5YCA
 | | Crystal structure of inner membrane protein Bqt4 in complex with LEM2 | | 分子名称: | Lap-Emerin-Man domain protein 2, Ubiquitin-like protein SMT3,Bouquet formation protein 4 | | 著者 | Chen, Y, Hu, C. | | 登録日 | 2017-09-07 | | 公開日 | 2018-11-14 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | | 主引用文献 | Structural insights into chromosome attachment to the nuclear envelope by an inner nuclear membrane protein Bqt4 in fission yeast.
Nucleic Acids Res., 47, 2019
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5Y18
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7X4P
 | | CD-NTase EfCdnE in complex with intermediate pppUpU | | 分子名称: | EfCdnE, MAGNESIUM ION, URIDINE 5'-TRIPHOSPHATE, ... | | 著者 | Chen, Y, Ko, T.P, Yang, C.S, Wang, Y.C, Hou, M.H. | | 登録日 | 2022-03-03 | | 公開日 | 2023-03-08 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Crystal structure and functional implications of cyclic di-pyrimidine-synthesizing cGAS/DncV-like nucleotidyltransferases.
Nat Commun, 14, 2023
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7X4A
 | | Native CD-NTase ClCdnE | | 分子名称: | ClCdnE | | 著者 | Chen, Y, Ko, T.P, Yang, C.S, Wang, Y.C, Hou, M.H. | | 登録日 | 2022-03-02 | | 公開日 | 2023-03-08 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | | 主引用文献 | Crystal structure and functional implications of cyclic di-pyrimidine-synthesizing cGAS/DncV-like nucleotidyltransferases.
Nat Commun, 14, 2023
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7X4C
 | | Native CD-NTase EfCdnE | | 分子名称: | EfCdnE, L(+)-TARTARIC ACID | | 著者 | Chen, Y, Ko, T.P, Yang, C.S, Wang, Y.C, Hou, M.H. | | 登録日 | 2022-03-02 | | 公開日 | 2023-03-08 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Crystal structure and functional implications of cyclic di-pyrimidine-synthesizing cGAS/DncV-like nucleotidyltransferases.
Nat Commun, 14, 2023
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