8FBP
 
 | | Glutamine synthetase from Pseudomonas aeruginosa, filament double-unit in compressed conformation | | Descriptor: | Glutamine synthetase | | Authors: | Phan, I.Q, Staker, B, Shek, R, Moser, T.H, Evans, J.E, van Voorhis, W.C, Myler, P.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | | Deposit date: | 2022-11-29 | | Release date: | 2024-02-14 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Glutamine synthetase from Pseudomonas aeruginosa, filament double-unit in compressed conformation
To Be Published
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2KN9
 | | Solution structure of zinc-substituted rubredoxin B (Rv3250c) from Mycobacterium tuberculosis. Seattle Structural Genomics Center for Infectious Disease target MytuD.01635.a | | Descriptor: | Rubredoxin, ZINC ION | | Authors: | Buchko, G.W, Hewitt, S.N, Napuli, A.J, Van Voorhis, W.C, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | | Deposit date: | 2009-08-20 | | Release date: | 2009-09-15 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Solution-state NMR structure and biophysical characterization of zinc-substituted rubredoxin B (Rv3250c) from Mycobacterium tuberculosis.
Acta Crystallogr.,Sect.F, 67, 2011
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2KOK
 | | Solution structure of an arsenate reductase (ArsC) related protein from Brucella melitensis. Seattle Structural Genomics Center for Infectious Disease target BrabA.00007.a. | | Descriptor: | arsenate reductase | | Authors: | Buchko, G.W, Hewitt, S.N, Napuli, A.J, Van Voorhis, W.C, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | | Deposit date: | 2009-09-23 | | Release date: | 2009-10-13 | | Last modified: | 2024-05-08 | | Method: | SOLUTION NMR | | Cite: | Solution structure of an arsenate reductase-related protein, YffB, from Brucella melitensis, the etiological agent responsible for brucellosis.
Acta Crystallogr.,Sect.F, 67, 2011
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3RP9
 | | Crystal Structure of the apo MapK from Toxoplasma Gondii, 25.m01780 or TGME49_007820 | | Descriptor: | Mitogen-activated protein kinase, SULFATE ION | | Authors: | Wernimont, A.K, Crombet, L, Pizarro, J.C, Crowther, G.J, Van Voorhis, W.C, Arrowsmith, C.H, Bountra, C, Weigelt, J, Edwards, A.M, Hui, R, Lin, Y.H, Structural Genomics Consortium (SGC) | | Deposit date: | 2011-04-26 | | Release date: | 2011-06-15 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal Structure of the apo MapK from Toxoplasma Gondii, 25.m01780 or TGME49_007820
To be Published
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2R2L
 | | Structure of Farnesyl Protein Transferase bound to PB-93 | | Descriptor: | FARNESYL DIPHOSPHATE, Farnesyltransferase subunit alpha, Farnesyltransferase subunit beta, ... | | Authors: | Strickland, C.O, Voorhis, W. | | Deposit date: | 2007-08-27 | | Release date: | 2008-03-11 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.23 Å) | | Cite: | Efficacy, pharmacokinetics, and metabolism of tetrahydroquinoline inhibitors of Plasmodium falciparum protein farnesyltransferase.
Antimicrob.Agents Chemother., 51, 2007
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3EJ0
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3EIY
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4TZR
 | | Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with inhibitor UW1561 | | Descriptor: | 1-{4-amino-3-[2-(cyclopropyloxy)quinolin-6-yl]-1H-pyrazolo[3,4-d]pyrimidin-1-yl}-2-methylpropan-2-ol, Calmodulin-domain protein kinase 1 | | Authors: | Merritt, E.A. | | Deposit date: | 2014-07-10 | | Release date: | 2014-08-27 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Development of an Orally Available and Central Nervous System (CNS) Penetrant Toxoplasma gondii Calcium-Dependent Protein Kinase 1 (TgCDPK1) Inhibitor with Minimal Human Ether-a-go-go-Related Gene (hERG) Activity for the Treatment of Toxoplasmosis.
J. Med. Chem., 59, 2016
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4MX9
 | | CDPK1 from Neospora caninum in complex with inhibitor UW1294 | | Descriptor: | 3-(6-ethoxynaphthalen-2-yl)-1-[(1-methylpiperidin-4-yl)methyl]-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Calmodulin-like domain protein kinase isoenzyme gamma, related | | Authors: | Merritt, E.A. | | Deposit date: | 2013-09-26 | | Release date: | 2013-10-09 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Neospora caninum Calcium-Dependent Protein Kinase 1 Is an Effective Drug Target for Neosporosis Therapy.
Plos One, 9, 2014
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4WG5
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4YSJ
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4YJN
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4WG3
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4WG4
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3TK1
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6AGT
 | | Crystal structure of PfKRS complexed with chromone inhibitor | | Descriptor: | COBALT (II) ION, FORMIC ACID, LYSINE, ... | | Authors: | Yogavel, M, Sharma, A, Sharma, A, Baragana, B, Walpole, C. | | Deposit date: | 2018-08-14 | | Release date: | 2019-03-13 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.953 Å) | | Cite: | Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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4ONA
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1GYQ
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3KHP
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3KRB
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3KSV
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3KRS
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3KPA
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3LLS
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3LC0
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