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2ADM
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BU of 2adm by Molmil
ADENINE-N6-DNA-METHYLTRANSFERASE TAQI
Descriptor: ADENINE-N6-DNA-METHYLTRANSFERASE TAQI, S-ADENOSYLMETHIONINE
Authors:Schluckebier, G, Saenger, W.
Deposit date:1996-07-15
Release date:1997-01-27
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Differential binding of S-adenosylmethionine S-adenosylhomocysteine and Sinefungin to the adenine-specific DNA methyltransferase M.TaqI.
J.Mol.Biol., 265, 1997
1AQJ
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BU of 1aqj by Molmil
STRUCTURE OF ADENINE-N6-DNA-METHYLTRANSFERASE TAQI
Descriptor: ADENINE-N6-DNA-METHYLTRANSFERASE TAQI, SINEFUNGIN
Authors:Schluckebier, G, Saenger, W.
Deposit date:1996-07-25
Release date:1997-02-12
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Differential binding of S-adenosylmethionine S-adenosylhomocysteine and Sinefungin to the adenine-specific DNA methyltransferase M.TaqI.
J.Mol.Biol., 265, 1997
1AQI
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BU of 1aqi by Molmil
STRUCTURE OF ADENINE-N6-DNA-METHYLTRANSFERASE TAQI
Descriptor: ADENINE-N6-DNA-METHYLTRANSFERASE TAQI, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Schluckebier, G, Saenger, W.
Deposit date:1996-07-25
Release date:1997-02-12
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Differential binding of S-adenosylmethionine S-adenosylhomocysteine and Sinefungin to the adenine-specific DNA methyltransferase M.TaqI.
J.Mol.Biol., 265, 1997
1QAN
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BU of 1qan by Molmil
THE STRUCTURE OF THE RRNA METHYLTRANSFERASE ERMC': IMPLICATIONS FOR THE REACTION MECHANISM
Descriptor: ACETATE ION, ERMC' METHYLTRANSFERASE, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Schluckebier, G, Zhong, P, Stewart, K.D, Kavanaugh, T.J, Abad-Zapatero, C.
Deposit date:1999-03-26
Release date:2000-03-29
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The 2.2 A structure of the rRNA methyltransferase ErmC' and its complexes with cofactor and cofactor analogs: implications for the reaction mechanism.
J.Mol.Biol., 289, 1999
1QAO
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BU of 1qao by Molmil
THE STRUCTURE OF THE RRNA METHYLTRANSFERASE ERMC': IMPLICATIONS FOR THE REACTION MECHANISM
Descriptor: ERMC' METHYLTRANSFERASE, S-ADENOSYLMETHIONINE
Authors:Schluckebier, G, Zhong, P, Stewart, K.D, Kavanaugh, T.J, Abad-Zapatero, C.
Deposit date:1999-03-26
Release date:2000-03-29
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The 2.2 A structure of the rRNA methyltransferase ErmC' and its complexes with cofactor and cofactor analogs: implications for the reaction mechanism.
J.Mol.Biol., 289, 1999
1QAM
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BU of 1qam by Molmil
THE STRUCTURE OF THE RRNA METHYLTRANSFERASE ERMC': IMPLICATIONS FOR THE REACTION MECHANISM
Descriptor: ACETATE ION, ERMC' METHYLTRANSFERASE
Authors:Schluckebier, G, Zhong, P, Stewart, K.D, Kavanaugh, T.J, Abad-Zapatero, C.
Deposit date:1999-03-25
Release date:2000-03-29
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The 2.2 A structure of the rRNA methyltransferase ErmC' and its complexes with cofactor and cofactor analogs: implications for the reaction mechanism.
J.Mol.Biol., 289, 1999
1QAQ
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BU of 1qaq by Molmil
THE STRUCTURE OF THE RRNA METHYLTRANSFERASE ERMC': IMPLICATIONS FOR THE REACTION MECHANISM
Descriptor: ERMC' RRNA METHYLTRANSFERASE, SINEFUNGIN
Authors:Schluckebier, G, Zhong, P, Stewart, K.D, Kavanaugh, T.J, Abad-Zapatero, C.
Deposit date:1999-03-28
Release date:2000-03-29
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The 2.2 A structure of the rRNA methyltransferase ErmC' and its complexes with cofactor and cofactor analogs: implications for the reaction mechanism.
J.Mol.Biol., 289, 1999
3ZU1
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BU of 3zu1 by Molmil
Structure of LysB29(Nepsilon omega-carboxyheptadecanoyl) des(B30) Human Insulin
Descriptor: CHLORIDE ION, INSULIN A CHAIN, INSULIN B CHAIN, ...
Authors:Schluckebier, G, Whittingham, J.
Deposit date:2011-07-13
Release date:2011-08-03
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure of Lysb29(Nepsilon Omega-Carboxyheptadecanoyl) Des(B30) Human Insulin
To be Published
8RRP
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BU of 8rrp by Molmil
Insulin Icodec - A14E B16H B25H B29Ne-C20 diacid-LgGlu-2xAdo desB30 human insulin
Descriptor: ACETATE ION, Insulin, Insulin B chain
Authors:Schluckebier, G, Johansson, E.
Deposit date:2024-01-23
Release date:2024-07-10
Last modified:2024-07-31
Method:X-RAY DIFFRACTION (2 Å)
Cite:Enhanced disulphide bond stability contributes to the once-weekly profile of insulin icodec.
Nat Commun, 15, 2024
8CN9
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BU of 8cn9 by Molmil
Factor VII binding Fab of the bispecific antibody HMB-001 in complex with Factor VII
Descriptor: CALCIUM ION, CESIUM ION, Coagulation factor VII, ...
Authors:Schluckebier, G, Johansson, E.
Deposit date:2023-02-22
Release date:2023-12-27
Last modified:2024-09-11
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:A bispecific antibody approach for the potential prophylactic treatment of inherited bleeding disorders.
Nat Cardiovasc Res, 3, 2024
8PJH
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BU of 8pjh by Molmil
Crystal structure of human insulin desB30 precursor with an Aspartate-Glycine-Lysine C-peptide in dimer (T2) conformation
Descriptor: Insulin
Authors:Schluckebier, G, Johansson, E.
Deposit date:2023-06-23
Release date:2023-11-08
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Molecular engineering of insulin for recombinant expression in yeast.
Trends Biotechnol, 42, 2024
8PJC
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BU of 8pjc by Molmil
Crystal structure of human insulin desB30 precursor with an Alanine-Alanine-Lysine C-peptide in dimer (T2) conformation
Descriptor: Insulin
Authors:Schluckebier, G, Johansson, E.
Deposit date:2023-06-23
Release date:2023-11-08
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Molecular engineering of insulin for recombinant expression in yeast.
Trends Biotechnol, 42, 2024
1TRP
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BU of 1trp by Molmil
X-RAY CRYSTALLOGRAPHIC AND CALORIMERIC STUDIES OF THE EFFECTS OF THE MUTATION TRP 59 TYR IN RIBONUCLEASE T1
Descriptor: CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE, RIBONUCLEASE T1 ISOZYME
Authors:Schluckebier, G, Saenger, W.
Deposit date:1993-07-06
Release date:1994-04-30
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:X-ray crystallographic and calorimetric studies of the effects of the mutation Trp59-->Tyr in ribonuclease T1.
Eur.J.Biochem., 220, 1994
5E94
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BU of 5e94 by Molmil
Antibody-bound Glucagon-like Peptide-1 receptor extracellular domain
Descriptor: Antibody Fab fragment heavy chain, Antibody Fab fragment light chain, Glucagon-like peptide 1 receptor
Authors:Soroka, V, Schluckebier, G, Reedtz-Runge, S.
Deposit date:2015-10-14
Release date:2016-08-24
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural insight into antibody-mediated antagonism of the Glucagon-like peptide-1 Receptor.
Sci Rep, 6, 2016
4IDW
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BU of 4idw by Molmil
Polycrystalline T6 Bovine Insulin: Anisotropic Lattice Evolution and Novel Structure Refinement Strategy
Descriptor: Insulin A chain, Insulin B chain, ZINC ION
Authors:Margiolaki, I, Giannopoulou, A.E, Wright, J.P, Knight, L, Norrman, M, Schluckebier, G, Fitch, A, Von Dreele, R.B.
Deposit date:2012-12-13
Release date:2013-06-05
Last modified:2024-10-30
Method:POWDER DIFFRACTION
Cite:High-resolution powder X-ray data reveal the T6 hexameric form of bovine insulin
Acta Crystallogr.,Sect.D, 69, 2013
8CHE
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BU of 8che by Molmil
TLT-1 binding Fab of the bispecific antibody HMB-001 in complex with the TLT-1 stalk peptide
Descriptor: Fab heavy chain, Fab light chain, Trem-like transcript 1 protein
Authors:Johansson, E, Schluckebier, G.
Deposit date:2023-02-07
Release date:2023-12-27
Last modified:2024-09-11
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:A bispecific antibody approach for the potential prophylactic treatment of inherited bleeding disorders.
Nat Cardiovasc Res, 3, 2024
2W44
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BU of 2w44 by Molmil
Structure DeltaA1-A4 insulin
Descriptor: CHLORIDE ION, INSULIN, RESORCINOL, ...
Authors:Thorsoee, K.S, Schlein, M, Brandt, J, Schluckebier, G, Naver, H.
Deposit date:2008-11-21
Release date:2009-12-22
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:Kinetic Evidence for the Sequential Association of Insulin Binding Sites 1 and 2 to the Insulin Receptor and the Influence of Receptor Isoform.
Biochemistry, 49, 2010
2WFV
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BU of 2wfv by Molmil
Crystal structure of DILP5 variant C4
Descriptor: PROBABLE INSULIN-LIKE PEPTIDE 5 A CHAIN, PROBABLE INSULIN-LIKE PEPTIDE 5 B CHAIN
Authors:Kulahin, N, Schluckebier, G, Sajid, W, De Meyts, P.
Deposit date:2009-04-15
Release date:2010-05-26
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural and Biological Properties of the Drosophila Insulin-Like Peptide 5 Show Evolutionary Conservation.
J.Biol.Chem., 286, 2011
2OM0
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BU of 2om0 by Molmil
Structure of human insulin in presence of urea at pH 6.5
Descriptor: CHLORIDE ION, Insulin A chain, Insulin B chain, ...
Authors:Norrman, M, Schluckebier, G.
Deposit date:2007-01-20
Release date:2007-12-04
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystallographic characterization of two novel crystal forms of human insulin induced by chaotropic agents and a shift in pH.
Bmc Struct.Biol., 7, 2007
2OLY
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BU of 2oly by Molmil
Structure of human insulin in presence of urea at pH 7.0
Descriptor: CHLORIDE ION, GLYCEROL, Insulin A chain, ...
Authors:Norrman, M, Schluckebier, G.
Deposit date:2007-01-20
Release date:2007-12-04
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystallographic characterization of two novel crystal forms of human insulin induced by chaotropic agents and a shift in pH.
Bmc Struct.Biol., 7, 2007
2OMH
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BU of 2omh by Molmil
Structure of human insulin cocrystallized with ARG-12 peptide in presence of urea
Descriptor: CHLORIDE ION, FORMAMIDE, Insulin A chain, ...
Authors:Norrman, M, Schluckebier, G.
Deposit date:2007-01-22
Release date:2007-03-27
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.36 Å)
Cite:Structural characterization of insulin NPH formulations.
EUR.J.PHARM.SCI., 30, 2007
2OM1
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BU of 2om1 by Molmil
Structure of human insulin in presence of thiocyanate at pH 6.5
Descriptor: GLYCEROL, Insulin A chain, Insulin B chain, ...
Authors:Norrman, M, Schluckebier, G.
Deposit date:2007-01-20
Release date:2007-12-04
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Crystallographic characterization of two novel crystal forms of human insulin induced by chaotropic agents and a shift in pH.
Bmc Struct.Biol., 7, 2007
2OMI
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BU of 2omi by Molmil
Structure of human insulin cocrystallized with protamine
Descriptor: CHLORIDE ION, Insulin A chain, Insulin B chain, ...
Authors:Norrman, M, Schluckebier, G.
Deposit date:2007-01-22
Release date:2007-03-27
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:Structural characterization of insulin NPH formulations.
EUR.J.PHARM.SCI., 30, 2007
6FF3
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BU of 6ff3 by Molmil
Crystal structure of Drosophila neural ectodermal development factor Imp-L1 with Human IGF-I
Descriptor: Insulin-like growth factor I, Neural/ectodermal development factor IMP-L2
Authors:Brzozowski, A.M, Kulahin, N, Kristensen, O, Schluckebier, G, Meyts, P.D, Viola, C.M.
Deposit date:2018-01-03
Release date:2018-09-26
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.57 Å)
Cite:Structures of insect Imp-L2 suggest an alternative strategy for regulating the bioavailability of insulin-like hormones.
Nat Commun, 9, 2018
6FEY
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BU of 6fey by Molmil
Crystal structure of Drosophila neural ectodermal development factor Imp-L2 with Drosophila DILP5 insulin
Descriptor: Neural/ectodermal development factor IMP-L2, Probable insulin-like peptide 5
Authors:Brzozowski, A.M, Kulahin, N, Kristensen, O, Schluckebier, G, Meyts, P.D.
Deposit date:2018-01-03
Release date:2018-09-26
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (3.48 Å)
Cite:Structures of insect Imp-L2 suggest an alternative strategy for regulating the bioavailability of insulin-like hormones.
Nat Commun, 9, 2018

 

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