5FNA
 
 | | Cryo-EM reconstruction of caspase-1 CARD | | Descriptor: | Caspase-1 | | Authors: | Li, Y, Lu, A, Schmidt, F.I, Yin, Q, Chen, S, Fu, T.M, Tong, A.B, Ploegh, H.L, Mao, Y, Wu, H. | | Deposit date: | 2015-11-11 | | Release date: | 2016-03-30 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (4.8 Å) | | Cite: | Molecular Basis of Caspase-1 Polymerization and its Inhibition by a Novel Capping Mechanism
Nat.Struct.Mol.Biol., 23, 2016
|
|
2QM4
 | | Crystal structure of human XLF/Cernunnos, a non-homologous end-joining factor | | Descriptor: | Non-homologous end-joining factor 1 | | Authors: | Li, Y, Chirgadze, D.Y, Sibanda, B.L, Bolanos-Garcia, V.M, Davies, O.R, Blundell, T.L. | | Deposit date: | 2007-07-14 | | Release date: | 2007-12-11 | | Last modified: | 2017-10-18 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal structure of human XLF/Cernunnos reveals unexpected differences from XRCC4 with implications for NHEJ.
Embo J., 27, 2008
|
|
3KEA
 | |
4N4Y
 | |
1WPA
 | |
4XVJ
 | |
7YTD
 | | Cryo-EM structure of four human FcmR bound to IgM-Fc/J | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fas apoptotic inhibitory molecule 3, Immunoglobulin J chain, ... | | Authors: | Li, Y, Shen, H, Xiao, J. | | Deposit date: | 2022-08-14 | | Release date: | 2023-02-01 | | Last modified: | 2023-05-03 | | Method: | ELECTRON MICROSCOPY (3.71 Å) | | Cite: | Immunoglobulin M perception by Fc mu R.
Nature, 615, 2023
|
|
7YSG
 | | Cryo-EM structure of human FcmR bound to sIgM | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fas apoptotic inhibitory molecule 3, ... | | Authors: | Li, Y, Shen, H, Xiao, J. | | Deposit date: | 2022-08-12 | | Release date: | 2023-02-01 | | Last modified: | 2023-05-03 | | Method: | ELECTRON MICROSCOPY (3.18 Å) | | Cite: | Immunoglobulin M perception by Fc mu R.
Nature, 615, 2023
|
|
7YTC
 | | Cryo-EM structure of human FcmR bound to IgM-Fc/J | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fas apoptotic inhibitory molecule 3, Immunoglobulin J chain, ... | | Authors: | Li, Y, Shen, H, Xiao, J. | | Deposit date: | 2022-08-14 | | Release date: | 2023-02-01 | | Last modified: | 2023-05-03 | | Method: | ELECTRON MICROSCOPY (3.39 Å) | | Cite: | Immunoglobulin M perception by Fc mu R.
Nature, 615, 2023
|
|
7YTE
 | |
8W8F
 | | human co-transcriptional RNA capping enzyme RNGTT-CMTR1 | | Descriptor: | Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1, DNA (36-MER), DNA (45-MER), ... | | Authors: | Li, Y, Wang, Q, Xu, Y, Li, Z. | | Deposit date: | 2023-09-02 | | Release date: | 2024-04-10 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Strcutures of co-transcriptional RNA capping enzymes on paused transcription complex
To Be Published
|
|
8W8E
 | | human co-transcriptional RNA capping enzyme RNGTT | | Descriptor: | DNA (36-MER), DNA (45-MER), DNA-directed RNA polymerase II subunit E, ... | | Authors: | Li, Y, Wang, Q, Xu, Y, Li, Z. | | Deposit date: | 2023-09-02 | | Release date: | 2024-04-10 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Strcutures of co-transcriptional RNA capping enzymes on paused transcription complex
To Be Published
|
|
3L2O
 | |
3KTQ
 | |
1HQR
 | | CRYSTAL STRUCTURE OF A SUPERANTIGEN BOUND TO THE HIGH-AFFINITY, ZINC-DEPENDENT SITE ON MHC CLASS II | | Descriptor: | HLA-DR ALPHA CHAIN, HLA-DR BETA CHAIN, MYELIN BASIC PROTEIN, ... | | Authors: | Li, Y, Li, H, Dimasi, N, Schlievert, P, Mariuzza, R. | | Deposit date: | 2000-12-19 | | Release date: | 2001-01-03 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Crystal structure of a superantigen bound to the high-affinity, zinc-dependent site on MHC class II.
Immunity, 14, 2001
|
|
7BV6
 | | Crystal structure of the autophagic STX17/SNAP29/VAMP8 SNARE complex | | Descriptor: | Synaptosomal-associated protein 29, Syntaxin-17, Vesicle-associated membrane protein 8 | | Authors: | Li, Y, Pan, L.F. | | Deposit date: | 2020-04-09 | | Release date: | 2020-09-02 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (3.05 Å) | | Cite: | Decoding three distinct states of the Syntaxin17 SNARE motif in mediating autophagosome-lysosome fusion.
Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
7BV4
 | | Crystal structure of STX17 LIR region in complex with GABARAP | | Descriptor: | DI(HYDROXYETHYL)ETHER, GLYCEROL, Gamma-aminobutyric acid receptor-associated protein, ... | | Authors: | Li, Y, Pan, L.F. | | Deposit date: | 2020-04-09 | | Release date: | 2020-09-02 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Decoding three distinct states of the Syntaxin17 SNARE motif in mediating autophagosome-lysosome fusion.
Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
6KXS
 | | Cryo-EM structure of human IgM-Fc in complex with the J chain and the ectodomain of pIgR | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin J chain, ... | | Authors: | Li, Y, Wang, G, Xiao, J. | | Deposit date: | 2019-09-12 | | Release date: | 2020-02-05 | | Last modified: | 2021-12-15 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structural insights into immunoglobulin M.
Science, 367, 2020
|
|
5F59
 | | The crystal structure of MLL3 SET domain | | Descriptor: | Histone-lysine N-methyltransferase 2C, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION | | Authors: | Li, Y, Lei, M, Chen, Y. | | Deposit date: | 2015-12-04 | | Release date: | 2016-02-24 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.801 Å) | | Cite: | Structural basis for activity regulation of MLL family methyltransferases.
Nature, 530, 2016
|
|
5F6L
 | | The crystal structure of MLL1 (N3861I/Q3867L) in complex with RbBP5 and Ash2L | | Descriptor: | Histone-lysine N-methyltransferase 2A, Retinoblastoma-binding protein 5, S-ADENOSYL-L-HOMOCYSTEINE, ... | | Authors: | Li, Y, Lei, M, Chen, Y. | | Deposit date: | 2015-12-06 | | Release date: | 2016-02-24 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural basis for activity regulation of MLL family methyltransferases.
Nature, 530, 2016
|
|
5F5E
 | |
5F6K
 | | Crystal structure of the MLL3-Ash2L-RbBP5 complex | | Descriptor: | Histone-lysine N-methyltransferase 2C, Retinoblastoma-binding protein 5, S-ADENOSYL-L-HOMOCYSTEINE, ... | | Authors: | Li, Y, Lei, M, Chen, Y. | | Deposit date: | 2015-12-06 | | Release date: | 2016-02-24 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.411 Å) | | Cite: | Structural basis for activity regulation of MLL family methyltransferases.
Nature, 530, 2016
|
|
5KTQ
 | | LARGE FRAGMENT OF TAQ DNA POLYMERASE BOUND TO DCTP | | Descriptor: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, PROTEIN (DNA POLYMERASE I) | | Authors: | Li, Y, Kong, Y, Korolev, S, Waksman, G. | | Deposit date: | 1998-09-22 | | Release date: | 1998-09-30 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structures of the Klenow fragment of Thermus aquaticus DNA polymerase I complexed with deoxyribonucleoside triphosphates.
Protein Sci., 7, 1998
|
|
7BRE
 | | The crystal structure of MLL2 in complex with ASH2L and RBBP5 | | Descriptor: | Histone-lysine N-methyltransferase 2B, Retinoblastoma-binding protein 5, S-ADENOSYL-L-HOMOCYSTEINE, ... | | Authors: | Li, Y, Zhao, L, Chen, Y. | | Deposit date: | 2020-03-28 | | Release date: | 2020-07-22 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.803 Å) | | Cite: | Crystal Structure of MLL2 Complex Guides the Identification of a Methylation Site on P53 Catalyzed by KMT2 Family Methyltransferases.
Structure, 28, 2020
|
|
7SOY
 | | The structure of the PP2A-B56gamma1 holoenzyme-PME-1 complex | | Descriptor: | Isoform Gamma-1 of Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform, Protein phosphatase methylesterase 1, Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, ... | | Authors: | Li, Y, Balakrishnan, V.K, Rowse, M, Novikova, I.V, Xing, Y. | | Deposit date: | 2021-11-01 | | Release date: | 2022-08-31 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Coupling to short linear motifs creates versatile PME-1 activities in PP2A holoenzyme demethylation and inhibition.
Elife, 11, 2022
|
|
