1IK1
| Solution Structure of an RNA Hairpin from HRV-14 | Descriptor: | 5'-R(*GP*GP*UP*AP*CP*UP*AP*UP*GP*UP*AP*CP*CP*A)-3' | Authors: | Huang, H, Alexandrov, A, Chen, X, Barnes III, T.W, Zhang, H, Dutta, K, Pascal, S.M. | Deposit date: | 2001-05-01 | Release date: | 2001-07-18 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structure of an RNA hairpin from HRV-14. Biochemistry, 40, 2001
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3CQ0
| Crystal Structure of TAL2_YEAST | Descriptor: | 1,2-ETHANEDIOL, GLYCEROL, Putative transaldolase YGR043C, ... | Authors: | Huang, H, Niu, L, Teng, M. | Deposit date: | 2008-04-01 | Release date: | 2009-04-07 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The crystal structure and identification of NQM1/YGR043C, a transaldolase from Saccharomyces cerevisiae Proteins, 73, 2008
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2G4A
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8JYU
| Acyl-ACP Synthetase structure bound to Decanoyl-AMP | Descriptor: | ADENOSINE MONOPHOSPHATE, Acyl-acyl carrier protein synthetase, DECANOIC ACID, ... | Authors: | Huang, H, Chang, S, Huang, M, Zhang, H, Zhou, C, Zhang, X, Feng, Y. | Deposit date: | 2023-07-03 | Release date: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.19 Å) | Cite: | Acyl-ACP Synthetase structure bound to Decanoyl-AMP To Be Published
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8JYL
| Acyl-ACP Synthetase structure bound to C10-AMS | Descriptor: | Acyl-acyl carrier protein synthetase, MAGNESIUM ION, [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl N-decanoylsulfamate | Authors: | Huang, H, Chang, S, Huang, M, Zhang, H, Zhou, C, Zhang, X, Feng, Y. | Deposit date: | 2023-07-03 | Release date: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.33 Å) | Cite: | Acyl-ACP Synthetase structure bound to C10-AMS To Be Published
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5KDM
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4Q9Q
| Crystal structure of an RNA aptamer bound to bromo-ligand analog in complex with Fab | Descriptor: | (5Z)-5-(3-bromobenzylidene)-2,3-dimethyl-3,5-dihydro-4H-imidazol-4-one, Fab BL3-6, HEAVY CHAIN, ... | Authors: | Huang, H, Suslov, N.B, Li, N.-S, Shelke, S.A, Evans, M.E, Koldobskaya, Y, Rice, P.A, Piccirilli, J.A. | Deposit date: | 2014-05-01 | Release date: | 2014-06-18 | Last modified: | 2017-07-26 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | A G-quadruplex-containing RNA activates fluorescence in a GFP-like fluorophore. Nat.Chem.Biol., 10, 2014
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4KZE
| Crystal structure of an RNA aptamer in complex with Fab | Descriptor: | BL3-6 Fab antibody, heavy chain, light chain, ... | Authors: | Huang, H, Suslov, N.B, Li, N, Koldobskaya, Y, Rice, P.A, Piccirilli, J.A. | Deposit date: | 2013-05-29 | Release date: | 2014-06-18 | Last modified: | 2014-07-30 | Method: | X-RAY DIFFRACTION (2.404 Å) | Cite: | A G-quadruplex-containing RNA activates fluorescence in a GFP-like fluorophore. Nat.Chem.Biol., 10, 2014
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4Q9R
| Crystal structure of an RNA aptamer bound to trifluoroethyl-ligand analog in complex with Fab | Descriptor: | (5Z)-5-(3,5-difluoro-4-hydroxybenzylidene)-2-methyl-3-(2,2,2-trifluoroethyl)-3,5-dihydro-4H-imidazol-4-one, Fab BL3-6, HEAVY CHAIN, ... | Authors: | Huang, H, Suslov, N.B, Li, N.-S, Shelke, S.A, Evans, M.E, Koldobskaya, Y, Rice, P.A, Piccirilli, J.A. | Deposit date: | 2014-05-01 | Release date: | 2014-06-18 | Last modified: | 2017-07-26 | Method: | X-RAY DIFFRACTION (3.12 Å) | Cite: | A G-quadruplex-containing RNA activates fluorescence in a GFP-like fluorophore. Nat.Chem.Biol., 10, 2014
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4O1O
| Crystal Structure of RNase L in complex with 2-5A | Descriptor: | Ribonuclease L, [[(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-4-[[(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-4-[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-3-hydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-3-hydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl] phosphono hydrogen phosphate | Authors: | Huang, H, Zeqiraj, E, Ceccarelli, D.F, Sicheri, F. | Deposit date: | 2013-12-16 | Release date: | 2014-02-05 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.27 Å) | Cite: | Dimeric structure of pseudokinase RNase L bound to 2-5A reveals a basis for interferon-induced antiviral activity. Mol.Cell, 53, 2014
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4O1P
| Crystal Structure of RNase L in complex with 2-5A and AMP-PNP | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Ribonuclease L, ... | Authors: | Huang, H, Zeqiraj, E, Ceccarelli, D.F, Sicheri, F. | Deposit date: | 2013-12-16 | Release date: | 2014-02-05 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Dimeric structure of pseudokinase RNase L bound to 2-5A reveals a basis for interferon-induced antiviral activity. Mol.Cell, 53, 2014
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4TQ4
| Structure of a UbiA homolog from Archaeoglobus fulgidus bound to DMAPP and Mg2+ | Descriptor: | DIMETHYLALLYL DIPHOSPHATE, MAGNESIUM ION, prenyltransferase | Authors: | Huang, H, Levin, E.J, Bai, Y, Zhou, M, New York Consortium on Membrane Protein Structure (NYCOMPS) | Deposit date: | 2014-06-10 | Release date: | 2014-07-16 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.5025 Å) | Cite: | Structure of a Membrane-Embedded Prenyltransferase Homologous to UBIAD1. Plos Biol., 12, 2014
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4TQ3
| Structure of a UbiA homolog from Archaeoglobus fulgidus bound to GPP and Mg2+ | Descriptor: | GERANYL DIPHOSPHATE, MAGNESIUM ION, Prenyltransferase | Authors: | Huang, H, Levin, E.J, Bai, Y, Zhou, M, New York Consortium on Membrane Protein Structure (NYCOMPS) | Deposit date: | 2014-06-10 | Release date: | 2014-07-16 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.4076 Å) | Cite: | Structure of a Membrane-Embedded Prenyltransferase Homologous to UBIAD1. Plos Biol., 12, 2014
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4KZD
| Crystal structure of an RNA aptamer in complex with fluorophore and Fab | Descriptor: | 4-(3,5-difluoro-4-hydroxybenzyl)-1,2-dimethyl-1H-imidazol-5-ol, BL3-6 Fab antibody, heavy chain, ... | Authors: | Huang, H, Suslov, N.B, Li, N, Koldobskaya, Y, Rice, P.A, Piccirilli, J.A. | Deposit date: | 2013-05-29 | Release date: | 2014-06-18 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.186 Å) | Cite: | A G-quadruplex-containing RNA activates fluorescence in a GFP-like fluorophore. Nat.Chem.Biol., 10, 2014
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4TQ6
| Structure of a UbiA homolog from Archaeoglobus fulgidus bound to Cd2+ | Descriptor: | CADMIUM ION, prenyltransferase | Authors: | Huang, H, Levin, E.J, Bai, Y, Zhou, M, New York Consortium on Membrane Protein Structure (NYCOMPS) | Deposit date: | 2014-06-10 | Release date: | 2014-07-16 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.0678 Å) | Cite: | Structure of a Membrane-Embedded Prenyltransferase Homologous to UBIAD1. Plos Biol., 12, 2014
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4TQ5
| Structure of a UbiA homolog from Archaeoglobus fulgidus | Descriptor: | octyl beta-D-glucopyranoside, prenyltransferase | Authors: | Huang, H, Levin, E.J, Bai, Y, Zhou, M, New York Consortium on Membrane Protein Structure (NYCOMPS) | Deposit date: | 2014-06-10 | Release date: | 2014-07-16 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3.2023 Å) | Cite: | Structure of a Membrane-Embedded Prenyltransferase Homologous to UBIAD1. Plos Biol., 12, 2014
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5BO0
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5BNV
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5BNX
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2KAS
| HNE-dG adduct mismatched with dA in basic solution | Descriptor: | (4S)-nonane-1,4-diol, 5'-D(*DGP*DCP*DTP*DAP*DGP*DCP*DGP*DAP*DGP*DTP*DCP*DC)-3', 5'-D(*DGP*DGP*DAP*DCP*DTP*DAP*DGP*DCP*DTP*DAP*DGP*DC)-3' | Authors: | Huang, H, Wang, H, Lloyd, R.S, Rizzo, C.J, Stone, M.P. | Deposit date: | 2008-11-13 | Release date: | 2009-05-26 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Conformational interconversion of the trans-4-hydroxynonenal-derived (6S,8R,11S) 1,N(2)-deoxyguanosine adduct when mismatched with deoxyadenosine in DNA Chem.Res.Toxicol., 22, 2009
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2K8U
| Solution NMR structure of trans-4-hydroxynonenal derived dG adduct of (6S,8R,11S)-configuration matched with dC | Descriptor: | (2S,5R)-5-pentyltetrahydrofuran-2-ol, 5'-D(*DGP*DCP*DTP*DAP*DGP*DCP*DGP*DAP*DGP*DTP*DCP*DC)-3', 5'-D(*DGP*DGP*DAP*DCP*DTP*DCP*DGP*DCP*DTP*DAP*DGP*DC)-3' | Authors: | Huang, H, Wang, H, Qi, N, Lloyd, R.S, Rizzo, C.J, Stone, M.P. | Deposit date: | 2008-09-23 | Release date: | 2008-11-04 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | The stereochemistry of trans-4-hydroxynonenal-derived exocyclic 1,N2-2'-deoxyguanosine adducts modulates formation of interstrand cross-links in the 5'-CpG-3' sequence. Biochemistry, 47, 2008
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2K8T
| Solution NMR structure of trans-4-hydroxynonenal derived dG adduct of (6R,8S,11R)-configuration opposite dC | Descriptor: | (2S,5R)-5-pentyltetrahydrofuran-2-ol, 5'-D(*DGP*DCP*DTP*DAP*DGP*DCP*DGP*DAP*DGP*DTP*DCP*DC)-3', 5'-D(*DGP*DGP*DAP*DCP*DTP*DCP*DGP*DCP*DTP*DAP*DGP*DC)-3' | Authors: | Huang, H, Wang, H, Qi, N, Lloyd, R.S, Rizzo, C.J, Stone, M.P. | Deposit date: | 2008-09-23 | Release date: | 2008-11-04 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | The stereochemistry of trans-4-hydroxynonenal-derived exocyclic 1,N2-2'-deoxyguanosine adducts modulates formation of interstrand cross-links in the 5'-CpG-3' sequence. Biochemistry, 47, 2008
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2KAR
| HNE-dG adduct mismatched with dA in acidic solution | Descriptor: | (4S)-nonane-1,4-diol, 5'-D(*DGP*DCP*DTP*DAP*DGP*DCP*DGP*DAP*DGP*DTP*DCP*DC)-3', 5'-D(*DGP*DGP*DAP*DCP*DTP*DAP*DGP*DCP*DTP*DAP*DGP*DC)-3' | Authors: | Huang, H, Wang, H, Lloyd, R.S, Rizzo, C.J, Stone, M.P. | Deposit date: | 2008-11-13 | Release date: | 2009-05-26 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Conformational interconversion of the trans-4-hydroxynonenal-derived (6S,8R,11S) 1,N(2)-deoxyguanosine adduct when mismatched with deoxyadenosine in DNA Chem.Res.Toxicol., 22, 2009
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8HSY
| Acyl-ACP Synthetase structure | Descriptor: | Acyl-acyl carrier protein synthetase | Authors: | Huang, H, Wang, C, Chang, S, Cui, T, Xu, Y, Zhang, H, Zhou, C, Zhang, X, Feng, Y. | Deposit date: | 2022-12-20 | Release date: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (2.53 Å) | Cite: | Acyl-ACP Synthetase structure To Be Published
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8I22
| Acyl-ACP synthetase structure bound to pimelic acid monoethyl ester | Descriptor: | 7-ethoxy-7-oxidanylidene-heptanoic acid, Acyl-acyl carrier protein synthetase | Authors: | Huang, H, Wang, C, Chang, S, Cui, T, Xu, Y, Zhang, H, Zhou, C, Zhang, X, Feng, Y. | Deposit date: | 2023-01-13 | Release date: | 2024-01-17 | Last modified: | 2024-04-03 | Method: | ELECTRON MICROSCOPY (2.15 Å) | Cite: | Acyl-ACP synthetase structure bound to pimelic acid monoethyl ester To Be Published
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