2K8U
Solution NMR structure of trans-4-hydroxynonenal derived dG adduct of (6S,8R,11S)-configuration matched with dC
Summary for 2K8U
Entry DOI | 10.2210/pdb2k8u/pdb |
Related | 2K8T |
Descriptor | 5'-D(*DGP*DCP*DTP*DAP*DGP*DCP*DGP*DAP*DGP*DTP*DCP*DC)-3', 5'-D(*DGP*DGP*DAP*DCP*DTP*DCP*DGP*DCP*DTP*DAP*DGP*DC)-3', (2S,5R)-5-pentyltetrahydrofuran-2-ol (3 entities in total) |
Functional Keywords | hne-dg (6s, 8r, 11s), hne derived dg adduct, trans-4-hydroxynonenal, dna |
Total number of polymer chains | 2 |
Total formula weight | 7485.02 |
Authors | Huang, H.,Wang, H.,Qi, N.,Lloyd, R.S.,Rizzo, C.J.,Stone, M.P. (deposition date: 2008-09-23, release date: 2008-11-04, Last modification date: 2024-05-22) |
Primary citation | Huang, H.,Wang, H.,Qi, N.,Lloyd, R.S.,Rizzo, C.J.,Stone, M.P. The stereochemistry of trans-4-hydroxynonenal-derived exocyclic 1,N2-2'-deoxyguanosine adducts modulates formation of interstrand cross-links in the 5'-CpG-3' sequence. Biochemistry, 47:11457-11472, 2008 Cited by PubMed: 18847226DOI: 10.1021/bi8011143 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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