4CXJ
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![BU of 4cxj by Molmil](/molmil-images/mine/4cxj) | BTB domain of KEAP1 C151W mutant | Descriptor: | KELCH-LIKE ECH-ASSOCIATED PROTEIN 1 | Authors: | Cleasby, A, Yon, J, Day, P.J, Richardson, C, Tickle, I.J, Williams, P.A, Callahan, J.F, Carr, R, Concha, N, Kerns, J.K, Qi, H, Sweitzer, T, Ward, P, Davies, T.G. | Deposit date: | 2014-04-07 | Release date: | 2014-06-18 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure of the Btb Domain of Keap1 and its Interaction with the Triterpenoid Antagonist Cddo. Plos One, 9, 2014
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2B1P
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![BU of 2b1p by Molmil](/molmil-images/mine/2b1p) | inhibitor complex of JNK3 | Descriptor: | 3-{6-[(2-CHLOROPHENYL)AMINO]-1H-INDAZOL-3-YL}-5-{[4-(DIMETHYLAMINO)BUTANOYL]AMINO}BENZOIC ACID, BETA-MERCAPTOETHANOL, Mitogen-activated protein kinase 10, ... | Authors: | Swahn, B.M, Huerta, F, Kallin, E, Malmstrom, J, Weigelt, T, Viklund, J, Womack, P, Xue, Y, Ohberg, L. | Deposit date: | 2005-09-16 | Release date: | 2006-09-16 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Design and synthesis of 6-anilinoindazoles as selective inhibitors of c-Jun N-terminal kinase-3 Bioorg.Med.Chem.Lett., 15, 2005
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3SQG
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![BU of 3sqg by Molmil](/molmil-images/mine/3sqg) | Crystal structure of a methyl-coenzyme M reductase purified from Black Sea mats | Descriptor: | (17[2]S)-17[2]-methylthio-coenzyme F43, 1-THIOETHANESULFONIC ACID, CALCIUM ION, ... | Authors: | Shima, S, Krueger, M, Weinert, T, Demmer, U, Thauer, R.K, Ermler, U. | Deposit date: | 2011-07-05 | Release date: | 2011-11-30 | Last modified: | 2017-11-08 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure of a methyl-coenzyme M reductase from Black Sea mats that oxidize methane anaerobically. Nature, 481, 2011
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5NR4
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![BU of 5nr4 by Molmil](/molmil-images/mine/5nr4) | Crystal structure of Clasp2 TOG1 domain | Descriptor: | CLIP-associating protein 2 | Authors: | Sharma, A, Olieric, N, Weinert, T, Olieric, V, Steinmetz, M.O. | Deposit date: | 2017-04-21 | Release date: | 2018-05-30 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.198 Å) | Cite: | CLASP Suppresses Microtubule Catastrophes through a Single TOG Domain. Dev. Cell, 46, 2018
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3IXV
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![BU of 3ixv by Molmil](/molmil-images/mine/3ixv) | Scorpion Hemocyanin resting state pseudo atomic model built based on cryo-EM density map | Descriptor: | Hemocyanin AA6 chain | Authors: | Cong, Y, Zhang, Q, Woolford, D, Schweikardt, T, Khant, H, Ludtke, S, Chiu, W, Decker, H. | Deposit date: | 2009-02-13 | Release date: | 2009-06-02 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (6.8 Å) | Cite: | Structural Mechanism of SDS-Induced Enzyme Activity of Scorpion Hemocyanin Revealed by Electron Cryomicroscopy. Structure, 17, 2009
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3IXW
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![BU of 3ixw by Molmil](/molmil-images/mine/3ixw) | Scorpion Hemocyanin activated state pseudo atomic model built based on cryo-EM density map | Descriptor: | Hemocyanin AA6 chain | Authors: | Cong, Y, Zhang, Q, Woolford, D, Schweikardt, T, Khant, H, Ludtke, S, Chiu, W, Decker, H. | Deposit date: | 2009-02-13 | Release date: | 2009-06-02 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (8 Å) | Cite: | Structural Mechanism of SDS-Induced Enzyme Activity of Scorpion Hemocyanin Revealed by Electron Cryomicroscopy. Structure, 17, 2009
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7Z01
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![BU of 7z01 by Molmil](/molmil-images/mine/7z01) | Z-SBTubA4 photoswitch bound to tubulin-DARPin D1 complex | Descriptor: | 2-methoxy-5-[2-(5,6,7-trimethoxy-1,3-benzothiazol-2-yl)ethyl]phenol, CALCIUM ION, Designed Ankyrin Repeat Protein (DARPIN) D1, ... | Authors: | Wranik, M, Weinert, T, Standfuss, J, Steinmetz, M. | Deposit date: | 2022-02-21 | Release date: | 2022-03-30 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | In Vivo Photocontrol of Microtubule Dynamics and Integrity, Migration and Mitosis, by the Potent GFP-Imaging-Compatible Photoswitchable Reagents SBTubA4P and SBTub2M. J.Am.Chem.Soc., 144, 2022
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7Z02
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![BU of 7z02 by Molmil](/molmil-images/mine/7z02) | Z-SBTub2M photoswitch bound to tubulin-DARPin D1 complex | Descriptor: | 6-methyl-2-[2-(3,4,5-trimethoxyphenyl)ethyl]-1,3-benzothiazole, Designed Ankyrin Repeat Protein (DARPIN) D1, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Wranik, M, Weinert, T, Standfuss, J, Steinmetz, M. | Deposit date: | 2022-02-21 | Release date: | 2022-03-30 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.36 Å) | Cite: | In Vivo Photocontrol of Microtubule Dynamics and Integrity, Migration and Mitosis, by the Potent GFP-Imaging-Compatible Photoswitchable Reagents SBTubA4P and SBTub2M. J.Am.Chem.Soc., 144, 2022
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2VD3
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![BU of 2vd3 by Molmil](/molmil-images/mine/2vd3) | The structure of histidine inhibited HisG from Methanobacterium thermoautotrophicum | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, ATP PHOSPHORIBOSYLTRANSFERASE, ... | Authors: | Lohkamp, B, Schweikert, T, Lapthorn, A.J. | Deposit date: | 2007-09-28 | Release date: | 2008-11-04 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | The Structure of Histidine Inhibited Hisg from Methanobacterium Thermoautotrophicum To be Published
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5T89
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![BU of 5t89 by Molmil](/molmil-images/mine/5t89) | Crystal structure of VEGF-A in complex with VEGFR-1 domains D1-6 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Vascular endothelial growth factor A, ... | Authors: | Markovic-Mueller, S, Stuttfeld, E, Asthana, M, Weinert, T, Bliven, S, Goldie, K.N, Kisko, K, Capitani, G, Ballmer-Hofer, K. | Deposit date: | 2016-09-07 | Release date: | 2017-02-01 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (4 Å) | Cite: | Structure of the Full-length VEGFR-1 Extracellular Domain in Complex with VEGF-A. Structure, 25, 2017
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6GBV
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![BU of 6gbv by Molmil](/molmil-images/mine/6gbv) | |
6GAY
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![BU of 6gay by Molmil](/molmil-images/mine/6gay) | |
6GB3
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![BU of 6gb3 by Molmil](/molmil-images/mine/6gb3) | |
6GBA
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![BU of 6gba by Molmil](/molmil-images/mine/6gba) | |
8SS1
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![BU of 8ss1 by Molmil](/molmil-images/mine/8ss1) | |
8SRZ
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![BU of 8srz by Molmil](/molmil-images/mine/8srz) | |
4WXM
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![BU of 4wxm by Molmil](/molmil-images/mine/4wxm) | FleQ REC domain from Pseudomonas aeruginosa PAO1 | Descriptor: | Transcriptional regulator FleQ | Authors: | Su, T, Liu, S, Gu, L. | Deposit date: | 2014-11-14 | Release date: | 2015-09-23 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The REC domain mediated dimerization is critical for FleQ from Pseudomonas aeruginosa to function as a c-di-GMP receptor and flagella gene regulator J.Struct.Biol., 192, 2015
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5XSN
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![BU of 5xsn by Molmil](/molmil-images/mine/5xsn) | The catalytic domain of GdpP with c-di-AMP | Descriptor: | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, MANGANESE (II) ION, Phosphodiesterase acting on cyclic dinucleotides | Authors: | Wang, F, Gu, L. | Deposit date: | 2017-06-14 | Release date: | 2018-01-31 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.501 Å) | Cite: | Structural and biochemical characterization of the catalytic domains of GdpP reveals a unified hydrolysis mechanism for the DHH/DHHA1 phosphodiesterase Biochem. J., 475, 2018
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5XSI
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![BU of 5xsi by Molmil](/molmil-images/mine/5xsi) | The catalytic domain of GdpP | Descriptor: | MANGANESE (II) ION, Phosphodiesterase acting on cyclic dinucleotides | Authors: | Wang, F, Gu, L. | Deposit date: | 2017-06-14 | Release date: | 2018-01-31 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural and biochemical characterization of the catalytic domains of GdpP reveals a unified hydrolysis mechanism for the DHH/DHHA1 phosphodiesterase Biochem. J., 475, 2018
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5XSP
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![BU of 5xsp by Molmil](/molmil-images/mine/5xsp) | The catalytic domain of GdpP with 5'-pApA | Descriptor: | ADENOSINE MONOPHOSPHATE, MANGANESE (II) ION, Phosphodiesterase acting on cyclic dinucleotides | Authors: | Wang, F, Gu, L. | Deposit date: | 2017-06-15 | Release date: | 2018-01-31 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.146 Å) | Cite: | Structural and biochemical characterization of the catalytic domains of GdpP reveals a unified hydrolysis mechanism for the DHH/DHHA1 phosphodiesterase Biochem. J., 475, 2018
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5XT3
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![BU of 5xt3 by Molmil](/molmil-images/mine/5xt3) | The catalytic domain of GdpP with c-di-GMP | Descriptor: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), MANGANESE (II) ION, Phosphodiesterase acting on cyclic dinucleotides | Authors: | Wang, F, Gu, L. | Deposit date: | 2017-06-16 | Release date: | 2018-01-31 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.591 Å) | Cite: | Structural and biochemical characterization of the catalytic domains of GdpP reveals a unified hydrolysis mechanism for the DHH/DHHA1 phosphodiesterase Biochem. J., 475, 2018
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5GPO
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![BU of 5gpo by Molmil](/molmil-images/mine/5gpo) | The sensor domain structure of the zinc-responsive histidine kinase CzcS from Pseudomonas Aeruginosa | Descriptor: | SULFATE ION, Sensor protein CzcS, ZINC ION | Authors: | Wang, D, Chen, W.Z, Huang, S.Q, Liu, X.C, Hu, Q.Y, Wei, T.B, Gan, J.H, Chen, H. | Deposit date: | 2016-08-03 | Release date: | 2017-08-09 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.701 Å) | Cite: | Structural basis of Zn(II) induced metal detoxification and antibiotic resistance by histidine kinase CzcS in Pseudomonas aeruginosa PLoS Pathog., 13, 2017
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4DOY
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![BU of 4doy by Molmil](/molmil-images/mine/4doy) | Crystal structure of Dibenzothiophene desulfurization enzyme C | Descriptor: | Dibenzothiophene desulfurization enzyme C, GLYCEROL | Authors: | Liu, S, Zhang, C, Zhu, D, Gu, L. | Deposit date: | 2012-02-12 | Release date: | 2013-02-13 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.789 Å) | Cite: | Crystal structure of DszC from Rhodococcus sp. XP at 1.79 angstrom Proteins, 82, 2014
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4ZXA
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![BU of 4zxa by Molmil](/molmil-images/mine/4zxa) | Crystal Structure of hydroquinone 1,2-dioxygenase PnpCD in complex with Cd2+ and 4-hydroxybenzonitrile | Descriptor: | 4-hydroxybenzonitrile, CADMIUM ION, Hydroquinone dioxygenase large subunit, ... | Authors: | Liu, S, Su, T, Zhang, C, Gu, L. | Deposit date: | 2015-05-20 | Release date: | 2015-09-02 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.488 Å) | Cite: | Crystal Structure of PnpCD, a Two-subunit Hydroquinone 1,2-Dioxygenase, Reveals a Novel Structural Class of Fe2+-dependent Dioxygenases. J.Biol.Chem., 290, 2015
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4ZXD
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![BU of 4zxd by Molmil](/molmil-images/mine/4zxd) | Crystal Structure of hydroquinone 1,2-dioxygenase PnpCD | Descriptor: | Hydroquinone dioxygenase large subunit, Hydroquinone dioxygenase small subunit | Authors: | Liu, S, Su, T, Zhang, C, Gu, L. | Deposit date: | 2015-05-20 | Release date: | 2015-09-02 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.052 Å) | Cite: | Crystal Structure of PnpCD, a Two-subunit Hydroquinone 1,2-Dioxygenase, Reveals a Novel Structural Class of Fe2+-dependent Dioxygenases. J.Biol.Chem., 290, 2015
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