5XT3

The catalytic domain of GdpP with c-di-GMP

Summary for 5XT3

Entry DOI	10.2210/pdb5xt3/pdb
Descriptor	Phosphodiesterase acting on cyclic dinucleotides, MANGANESE (II) ION, 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), ... (4 entities in total)
Functional Keywords	phosphodiesterase, hydrolase
Biological source	Staphylococcus aureus
Total number of polymer chains	2
Total formula weight	77003.24
Authors	Wang, F.,Gu, L. (deposition date: 2017-06-16, release date: 2018-01-31, Last modification date: 2023-11-22)
Primary citation	Wang, F.,He, Q.,Su, K.,Wei, T.,Xu, S.,Gu, L. Structural and biochemical characterization of the catalytic domains of GdpP reveals a unified hydrolysis mechanism for the DHH/DHHA1 phosphodiesterase Biochem. J., 475:191-205, 2018 Cited by PubMed: 29203646 DOI: 10.1042/BCJ20170739 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.591 Å)

Structure validation