1W20
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![BU of 1w20 by Molmil](/molmil-images/mine/1w20) | Structure of Neuraminidase from English duck subtype N6 complexed with 30 mM sialic acid (NANA, Neu5Ac), crystal soaked for 3 hours at 291 K | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Rudino-Pinera, E, Tunnah, P, Crennell, S.J, Webster, R.G, Laver, W.G, Garman, E.F. | Deposit date: | 2004-06-24 | Release date: | 2006-01-25 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.08 Å) | Cite: | The Crystal Structure of Type a Influenza Virus Neuraminidase of the N6 Subtype Reveals the Existence of Two Separate Neu5Ac Binding Sites To be Published
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4IOF
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![BU of 4iof by Molmil](/molmil-images/mine/4iof) | Crystal structure analysis of Fab-bound human Insulin Degrading Enzyme (IDE) | Descriptor: | Fab-bound IDE, heavy chain, light chain, ... | Authors: | McCord, L.A, Liang, W.G, Hoey, R, Dowdell, E, Koide, A, Koide, S, Tang, W.J. | Deposit date: | 2013-01-07 | Release date: | 2013-07-24 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.353 Å) | Cite: | Conformational states and recognition of amyloidogenic peptides of human insulin-degrading enzyme. Proc.Natl.Acad.Sci.USA, 110, 2013
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1W21
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![BU of 1w21 by Molmil](/molmil-images/mine/1w21) | Structure of Neuraminidase from English duck subtype N6 complexed with 30 mM sialic acid (NANA, Neu5Ac), crystal soaked for 43 hours at 291 K. | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Rudino-Pinera, E, Tunnah, P, Crennell, S.J, Webster, R.G, Laver, W.G, Garman, E.F. | Deposit date: | 2004-06-25 | Release date: | 2006-01-25 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.08 Å) | Cite: | The Crystal Structure of Type a Influenza Virus Neuraminidase of the N6 Subtype Reveals the Existence of Two Separate Neu5Ac Binding Sites To be Published
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4K7A
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![BU of 4k7a by Molmil](/molmil-images/mine/4k7a) | |
1W1X
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![BU of 1w1x by Molmil](/molmil-images/mine/1w1x) | Structure of Neuraminidase from English duck subtype N6 complexed with 30 mM sialic acid (NANA, Neu5Ac), crystal soaked for 3 hours at 277 K. | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Rudino-Pinera, E, Tunnah, P, Crennell, S.J, Webster, R.G, Laver, W.G, Garman, E.F. | Deposit date: | 2004-06-24 | Release date: | 2006-01-25 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The Crystal Structure of Type a Influenza Virus Neuraminidase of the N6 Subtype Reveals the Existence of Two Separate Neu5Ac Binding Sites To be Published
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4L3T
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![BU of 4l3t by Molmil](/molmil-images/mine/4l3t) | Crystal Structure of Substrate-free Human Presequence Protease | Descriptor: | ACETATE ION, GLYCEROL, Presequence protease, ... | Authors: | King, J.V, Liang, W.G, Tang, W.J. | Deposit date: | 2013-06-06 | Release date: | 2013-07-03 | Last modified: | 2014-07-23 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Molecular basis of substrate recognition and degradation by human presequence protease. Structure, 22, 2014
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3H42
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![BU of 3h42 by Molmil](/molmil-images/mine/3h42) | Crystal structure of PCSK9 in complex with Fab from LDLR competitive antibody | Descriptor: | Fab from LDLR competitive antibody: Heavy chain, Fab from LDLR competitive antibody: Light chain, Proprotein convertase subtilisin/kexin type 9, ... | Authors: | Piper, D.E, Walker, N.P.C, Romanow, W.G, Thibault, S.T, Tsai, M.M, Yang, E. | Deposit date: | 2009-04-17 | Release date: | 2009-05-05 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | From the Cover: A proprotein convertase subtilisin/kexin type 9 neutralizing antibody reduces serum cholesterol in mice and nonhuman primates. Proc.Natl.Acad.Sci.USA, 106, 2009
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1XDN
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![BU of 1xdn by Molmil](/molmil-images/mine/1xdn) | High resolution crystal structure of an editosome enzyme from trypanosoma brucei: RNA editing ligase 1 | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, RNA editing ligase MP52 | Authors: | Deng, J, Schnaufer, A, Salavati, R, Stuart, K.D, Hol, W.G. | Deposit date: | 2004-09-07 | Release date: | 2004-12-07 | Last modified: | 2014-09-10 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | High resolution crystal structure of a key editosome enzyme from Trypanosoma brucei: RNA editing ligase 1. J.Mol.Biol., 343, 2004
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1Y28
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![BU of 1y28 by Molmil](/molmil-images/mine/1y28) | Crystal structure of the R220A metBJFIXL HEME domain | Descriptor: | PROTOPORPHYRIN IX CONTAINING FE, Sensor protein fixL | Authors: | Dunham, C.M, Dioum, E.M, Tuckerman, J.R, Gonzalez, G, Scott, W.G, Gilles-Gonzalez, M.A. | Deposit date: | 2004-11-21 | Release date: | 2004-12-07 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | A distal arginine in the oxygen-sensing heme-PAS domains is essential to ligand binding, signal transduction, and structure Biochemistry, 42, 2003
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1Z6F
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![BU of 1z6f by Molmil](/molmil-images/mine/1z6f) | Crystal structure of penicillin-binding protein 5 from E. coli in complex with a boronic acid inhibitor | Descriptor: | GLYCEROL, N1-[(1R)-1-(DIHYDROXYBORYL)ETHYL]-N2-[(TERT-BUTOXYCARBONYL)-D-GAMMA-GLUTAMYL]-N6-[(BENZYLOXY)CARBONYL-L-LYSINAMIDE, Penicillin-binding protein 5 | Authors: | Nicola, G, Peddi, S, Stefanova, M, Nicholas, R.A, Gutheil, W.G, Davies, C. | Deposit date: | 2005-03-22 | Release date: | 2005-06-21 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal Structure of Escherichia coli Penicillin-Binding Protein 5 Bound to a Tripeptide Boronic Acid Inhibitor: A Role for Ser-110 in Deacylation. Biochemistry, 44, 2005
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4MHE
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![BU of 4mhe by Molmil](/molmil-images/mine/4mhe) | Crystal structure of CC-chemokine 18 | Descriptor: | ACETATE ION, C-C motif chemokine 18 | Authors: | Liang, W.G, Tang, W.-J. | Deposit date: | 2013-08-29 | Release date: | 2014-09-03 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structures of human CCL18, CCL3, and CCL4 reveal molecular determinants for quaternary structures and sensitivity to insulin-degrading enzyme. J.Mol.Biol., 427, 2015
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4KGO
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![BU of 4kgo by Molmil](/molmil-images/mine/4kgo) | |
4KSS
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![BU of 4kss by Molmil](/molmil-images/mine/4kss) | Crystal Structure of Vibrio cholerae ATPase GspsE Hexamer | Descriptor: | Type II secretion system protein E, hemolysin-coregulated protein | Authors: | Hol, W.G, Turley, S, Lu, C.Y, Park, Y.J. | Deposit date: | 2013-05-17 | Release date: | 2013-09-04 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (7.58 Å) | Cite: | Hexamers of the Type II Secretion ATPase GspE from Vibrio cholerae with Increased ATPase Activity. Structure, 21, 2013
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4KGH
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![BU of 4kgh by Molmil](/molmil-images/mine/4kgh) | |
3SBQ
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![BU of 3sbq by Molmil](/molmil-images/mine/3sbq) | Pseudomonas stutzeri nitrous oxide reductase, P65 crystal form | Descriptor: | CALCIUM ION, CHLORIDE ION, DINUCLEAR COPPER ION, ... | Authors: | Pomowski, A, Zumft, W.G, Kroneck, P.M.H, Einsle, O. | Deposit date: | 2011-06-06 | Release date: | 2011-08-10 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | N2O binding at a [4Cu:2S] copper-sulphur cluster in nitrous oxide reductase. Nature, 477, 2011
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1A35
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![BU of 1a35 by Molmil](/molmil-images/mine/1a35) | HUMAN TOPOISOMERASE I/DNA COMPLEX | Descriptor: | DNA (5'-D(*AP*AP*AP*AP*AP*GP*AP*CP*TP*TP*AP*GP*AP*AP*AP*AP*AP*(BRU)P*(BRU)P*TP*TP*T)-3'), DNA (5'-D(*AP*AP*AP*AP*AP*TP*+UP*+UP*+UP*+UP*CP*+UP*AP*AP*GP*TP*CP*TP*TP*TP*+ UP*T)-3'), PROTEIN (DNA TOPOISOMERASE I) | Authors: | Redinbo, M.R, Stewart, L, Kuhn, P, Champoux, J.J, Hol, W.G. | Deposit date: | 1998-01-29 | Release date: | 1998-08-28 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structures of human topoisomerase I in covalent and noncovalent complexes with DNA. Science, 279, 1998
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1B1B
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![BU of 1b1b by Molmil](/molmil-images/mine/1b1b) | IRON DEPENDENT REGULATOR | Descriptor: | PROTEIN (IRON DEPENDENT REGULATOR), SULFATE ION, ZINC ION | Authors: | Pohl, E, Holmes, R.K, Hol, W.G. | Deposit date: | 1998-11-19 | Release date: | 1999-12-03 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structure of the iron-dependent regulator (IdeR) from Mycobacterium tuberculosis shows both metal binding sites fully occupied. J.Mol.Biol., 285, 1999
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1B5S
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![BU of 1b5s by Molmil](/molmil-images/mine/1b5s) | DIHYDROLIPOYL TRANSACETYLASE (E.C.2.3.1.12) CATALYTIC DOMAIN (RESIDUES 184-425) FROM BACILLUS STEAROTHERMOPHILUS | Descriptor: | DIHYDROLIPOAMIDE ACETYLTRANSFERASE | Authors: | Izard, T, Aevarsson, A, Allen, M.D, Westphal, A.H, Perham, R.N, De Kok, A, Hol, W.G. | Deposit date: | 1999-01-10 | Release date: | 1999-02-16 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (4.4 Å) | Cite: | Principles of quasi-equivalence and Euclidean geometry govern the assembly of cubic and dodecahedral cores of pyruvate dehydrogenase complexes. Proc.Natl.Acad.Sci.USA, 96, 1999
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1RQC
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![BU of 1rqc by Molmil](/molmil-images/mine/1rqc) | Crystals of peptide deformylase from Plasmodium falciparum with ten subunits per asymmetric unit reveal critical characteristics of the active site for drug design | Descriptor: | COBALT (II) ION, formylmethionine deformylase | Authors: | Robien, M.A, Nguyen, K.T, Kumar, A, Hirsh, I, Turley, S, Pei, D, Hol, W.G. | Deposit date: | 2003-12-04 | Release date: | 2004-01-20 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | An improved crystal form of Plasmodium falciparum peptide deformylase Protein Sci., 13, 2004
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2CHB
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![BU of 2chb by Molmil](/molmil-images/mine/2chb) | CHOLERA TOXIN B-PENTAMER COMPLEXED WITH GM1 PENTASACCHARIDE | Descriptor: | CHOLERA TOXIN, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-[N-acetyl-alpha-neuraminic acid-(2-3)]beta-D-galactopyranose, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-[N-acetyl-alpha-neuraminic acid-(2-3)]beta-D-galactopyranose-(1-4)-beta-D-glucopyranose | Authors: | Merritt, E.A, Hol, W.G.J. | Deposit date: | 1997-06-03 | Release date: | 1997-12-03 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural studies of receptor binding by cholera toxin mutants. Protein Sci., 6, 1997
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7L7V
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![BU of 7l7v by Molmil](/molmil-images/mine/7l7v) | Crystal structure of Arabidopsis NRG1.1 CC-R domain K94E/K96E/R99E/K100E/R103E/K106E/K110E mutant | Descriptor: | Probable disease resistance protein At5g66900 | Authors: | Walton, W.G, Wan, L, Lietzan, A.D, Redinbo, M.R, Dangl, J.L. | Deposit date: | 2020-12-30 | Release date: | 2021-06-16 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Plant "helper" immune receptors are Ca 2+ -permeable nonselective cation channels. Science, 373, 2021
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7L7W
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![BU of 7l7w by Molmil](/molmil-images/mine/7l7w) | Crystal structure of Arabidopsis NRG1.1 CC-R domain K94E/K96E mutant | Descriptor: | NICKEL (II) ION, Probable disease resistance protein At5g66900 | Authors: | Walton, W.G, Wan, L, Lietzan, A.D, Redinbo, M.R, Dangl, J.L. | Deposit date: | 2020-12-30 | Release date: | 2021-06-16 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Plant "helper" immune receptors are Ca 2+ -permeable nonselective cation channels. Science, 373, 2021
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7KFO
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![BU of 7kfo by Molmil](/molmil-images/mine/7kfo) | Crystal structure of the MarR family transcriptional regulator from Variovorax paradoxus bound to Indole 3 acetic acid | Descriptor: | 1H-INDOL-3-YLACETIC ACID, SULFATE ION, Transcriptional regulator, ... | Authors: | Walton, W.G, Redinbo, M.R, Dangl, J.L. | Deposit date: | 2020-10-14 | Release date: | 2021-11-10 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Diverse MarR bacterial regulators of auxin catabolism in the plant microbiome. Nat Microbiol, 7, 2022
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7KFQ
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![BU of 7kfq by Molmil](/molmil-images/mine/7kfq) | Crystal structure of the MarR family transcriptional regulator from Variovorax paradoxus bound to 1H-Indole-3-Carboxylic Acid | Descriptor: | 1H-INDOLE-3-CARBOXYLIC ACID, SULFATE ION, Transcriptional regulator, ... | Authors: | Walton, W.G, Redinbo, M.R, Dangl, J.L. | Deposit date: | 2020-10-14 | Release date: | 2021-11-10 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Diverse MarR bacterial regulators of auxin catabolism in the plant microbiome. Nat Microbiol, 7, 2022
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7KFS
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![BU of 7kfs by Molmil](/molmil-images/mine/7kfs) | Crystal structure of the MarR family transcriptional regulator from Variovorax paradoxus bound to Benzoic Acid | Descriptor: | BENZOIC ACID, SULFATE ION, Transcriptional regulator, ... | Authors: | Walton, W.G, Redinbo, M.R, Dangl, J.L. | Deposit date: | 2020-10-14 | Release date: | 2021-11-10 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Diverse MarR bacterial regulators of auxin catabolism in the plant microbiome. Nat Microbiol, 7, 2022
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