6QH7
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![BU of 6qh7 by Molmil](/molmil-images/mine/6qh7) | AP2 clathrin adaptor mu2T156-phosphorylated core with two cargo peptides in open+ conformation | Descriptor: | ADAPTOR-RELATED PROTEIN COMPLEX 2, MU 2 SUBUNIT, C-TERMINAL DOMAIN, ... | Authors: | Wrobel, A.G, Owen, D.J, McCoy, A.J, Evans, P.R. | Deposit date: | 2019-01-15 | Release date: | 2019-09-04 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Temporal Ordering in Endocytic Clathrin-Coated Vesicle Formation via AP2 Phosphorylation. Dev.Cell, 50, 2019
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6QSY
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6B3D
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6W1S
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![BU of 6w1s by Molmil](/molmil-images/mine/6w1s) | Atomic model of the mammalian Mediator complex | Descriptor: | Mediator of RNA polymerase II transcription subunit 1, Mediator of RNA polymerase II transcription subunit 10, Mediator of RNA polymerase II transcription subunit 11, ... | Authors: | Zhao, H, Young, N, Asturias, F. | Deposit date: | 2020-03-04 | Release date: | 2021-03-10 | Method: | ELECTRON MICROSCOPY (4.02 Å) | Cite: | A Pliable Mediator Acts as a Functional Rather Than an Architectural Bridge between Promoters and Enhancers. Cell, 178, 2019
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3ZNR
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![BU of 3znr by Molmil](/molmil-images/mine/3znr) | HDAC7 bound with inhibitor TMP269 | Descriptor: | HISTONE DEACETYLASE 7, N-{[4-(4-phenyl-1,3-thiazol-2-yl)tetrahydro-2H-pyran-4-yl]methyl}-3-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide, POTASSIUM ION, ... | Authors: | Lobera, m, madauss, k, pohlhaus, d, trump, r, nolan, m. | Deposit date: | 2013-02-15 | Release date: | 2013-03-27 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Selective Class Iia Histone Deacetylase Inhibition Via a Non-Chelating Zinc Binding Group Nat.Chem.Biol., 9, 2013
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6J6Y
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![BU of 6j6y by Molmil](/molmil-images/mine/6j6y) | FGFR4 D2 - Fab complex | Descriptor: | Fab Heavy chain, Fab light chain, Fibroblast growth factor receptor 4 | Authors: | Takahashi, M, Hanzawa, H. | Deposit date: | 2019-01-16 | Release date: | 2019-08-07 | Last modified: | 2019-10-16 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Preclinical Development of U3-1784, a Novel FGFR4 Antibody Against Cancer, and Avoidance of Its On-target Toxicity. Mol.Cancer Ther., 18, 2019
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1SFC
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![BU of 1sfc by Molmil](/molmil-images/mine/1sfc) | NEURONAL SYNAPTIC FUSION COMPLEX | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, PROTEIN (SNAP-25B), PROTEIN (SYNAPTOBREVIN 2), ... | Authors: | Sutton, R.B, Brunger, A.T. | Deposit date: | 1998-08-24 | Release date: | 1998-10-28 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of a SNARE complex involved in synaptic exocytosis at 2.4 A resolution. Nature, 395, 1998
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5MB1
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![BU of 5mb1 by Molmil](/molmil-images/mine/5mb1) | STRUCTURE OF THE LECB LECTIN FROM PSEUDOMONAS AERUGINOSA STRAIN PA14 IN COMPLEX WITH 2,4,6-Trimethylphenylsulfonamide-N-methyl-L-fucopyranoside | Descriptor: | CALCIUM ION, CITRATE ANION, Fucose-binding lectin PA-IIL, ... | Authors: | Sommer, R, Imberty, A, Titz, A, Varrot, A. | Deposit date: | 2016-11-07 | Release date: | 2017-12-20 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Glycomimetic, Orally Bioavailable LecB Inhibitors Block Biofilm Formation of Pseudomonas aeruginosa. J. Am. Chem. Soc., 140, 2018
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5MAZ
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![BU of 5maz by Molmil](/molmil-images/mine/5maz) | STRUCTURE OF THE LECB LECTIN FROM PSEUDOMONAS AERUGINOSA STRAIN PA14 IN COMPLEX WITH 3-Thiophenesulfonamide-2,5-dimethyl-N-methyl-beta-L-fucopyranoside | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, Fucose-binding lectin PA-IIL, ... | Authors: | Sommer, R, Imberty, A, Titz, A, Varrot, A. | Deposit date: | 2016-11-07 | Release date: | 2017-12-20 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Discovery of a new class of C-glycoside based inhibitors of the virulence factor LecB from Pseudomonas aeruginosa To Be Published
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1MZW
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![BU of 1mzw by Molmil](/molmil-images/mine/1mzw) | Crystal structure of a U4/U6 snRNP complex between human spliceosomal cyclophilin H and a U4/U6-60K peptide | Descriptor: | U-snRNP-associated cyclophilin, U4/U6 snrnp 60kDa protein | Authors: | Reidt, U, Wahl, M.C, Horowitz, D.S, Luehrmann, R, Ficner, R. | Deposit date: | 2002-10-10 | Release date: | 2003-08-19 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of a complex between human spliceosomal cyclophilin H and a U4/U6 snRNP-60K peptide J.Mol.Biol., 331, 2003
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5MAY
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![BU of 5may by Molmil](/molmil-images/mine/5may) | STRUCTURE OF THE LECB LECTIN FROM PSEUDOMONAS AERUGINOSA STRAIN PA14 IN COMPLEX WITH 2-Thiophenesulfonamide-N-(beta-L-fucopyranosyl methyl) | Descriptor: | CALCIUM ION, Fucose-binding lectin PA-IIL, N-methyl-2-thiophenesulfonamide, ... | Authors: | Sommer, R, Imberty, A, Titz, A, Varrot, A. | Deposit date: | 2016-11-07 | Release date: | 2017-12-20 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Glycomimetic, Orally Bioavailable LecB Inhibitors Block Biofilm Formation of Pseudomonas aeruginosa. J. Am. Chem. Soc., 140, 2018
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2V75
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![BU of 2v75 by Molmil](/molmil-images/mine/2v75) | N-terminal domain of Nab2 | Descriptor: | NUCLEAR POLYADENYLATED RNA-BINDING PROTEIN NAB2 | Authors: | Grant, R.P, Marshall, N.J, Stewart, M. | Deposit date: | 2007-07-26 | Release date: | 2008-01-29 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure of the N-Terminal Mlp1-Binding Domain of the Saccharomyces Cerevisiae Mrna-Binding Protein, Nab2. J.Mol.Biol., 376, 2008
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1SOP
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2XTD
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![BU of 2xtd by Molmil](/molmil-images/mine/2xtd) | Structure of the TBL1 tetramerisation domain | Descriptor: | TBL1 F-BOX-LIKE/WD REPEAT-CONTAINING PROTEIN TBL1X | Authors: | Oberoi, J, Fairall, L, Watson, P.J, Greenwood, J.A, Schwabe, J.W.R. | Deposit date: | 2010-10-06 | Release date: | 2011-01-19 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural Basis for the Assembly of the Smrt/Ncor Core Transcriptional Repression Machinery. Nat.Struct.Mol.Biol., 18, 2011
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8B6N
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8B6P
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7O06
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7NWJ
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7O3B
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7O0S
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1GL2
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![BU of 1gl2 by Molmil](/molmil-images/mine/1gl2) | Crystal structure of an endosomal SNARE core complex | Descriptor: | ENDOBREVIN, SYNTAXIN 7, SYNTAXIN 8, ... | Authors: | Antonin, W, Becker, S, Jahn, R, Schneider, T.R. | Deposit date: | 2001-08-22 | Release date: | 2002-01-15 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal Structure of the Endosomal Snare Complex Reveals Common Structural Principles of All Snares. Nat.Struct.Biol., 9, 2001
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1E6I
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7LTJ
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![BU of 7ltj by Molmil](/molmil-images/mine/7ltj) | Room-temperature X-ray structure of SARS-CoV-2 main protease (3CL Mpro) in complex with a non-covalent inhibitor Mcule-5948770040 | Descriptor: | 3C-like proteinase, 6-[4-(3,4-dichlorophenyl)piperazin-1-yl]carbonyl-1~{H}-pyrimidine-2,4-dione | Authors: | Kovalevsky, A, Kneller, D.W, Coates, L. | Deposit date: | 2021-02-19 | Release date: | 2021-03-03 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | High-Throughput Virtual Screening and Validation of a SARS-CoV-2 Main Protease Noncovalent Inhibitor. J.Chem.Inf.Model., 62, 2022
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6SOS
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6SOK
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![BU of 6sok by Molmil](/molmil-images/mine/6sok) | |