2H35
| Solution structure of Human normal adult hemoglobin | Descriptor: | Hemoglobin alpha subunit, Hemoglobin beta subunit, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Fan, J.S, Yang, D. | Deposit date: | 2006-05-22 | Release date: | 2006-11-14 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | A new strategy for structure determination of large proteins in solution without deuteration Nat.Methods, 3, 2006
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2H25
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2KZ1
| Inter-molecular interactions in a 44 kDa interferon-receptor complex detected by asymmetric back-protonation and 2D NOESY | Descriptor: | Interferon alpha-2, Soluble IFN alpha/beta receptor | Authors: | Nudelman, I, Akabayov, S.R, Schnur, E, Biron, Z, Levy, R, Xu, Y, Yang, D, Anglister, J. | Deposit date: | 2010-06-10 | Release date: | 2010-06-23 | Last modified: | 2021-08-18 | Method: | SOLUTION NMR | Cite: | Intermolecular interactions in a 44 kDa interferon-receptor complex detected by asymmetric reverse-protonation and two-dimensional NOESY Biochemistry, 49, 2010
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2L7V
| Quindoline/G-quadruplex complex | Descriptor: | DNA (5'-D(*TP*GP*AP*GP*GP*GP*TP*GP*GP*GP*TP*AP*GP*GP*GP*TP*GP*GP*GP*TP*AP*A)-3'), N,N-diethyl-N'-(10H-indolo[3,2-b]quinolin-11-yl)ethane-1,2-diamine, POTASSIUM ION | Authors: | Dai, J, Carver, M, Mathad, R, Yang, D. | Deposit date: | 2010-12-23 | Release date: | 2011-11-09 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Solution Structure of a 2:1 Quindoline-c-MYC G-Quadruplex: Insights into G-Quadruplex-Interactive Small Molecule Drug Design. J.Am.Chem.Soc., 133, 2011
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2LBY
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6D9G
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2L9F
| NMR solution structure of meACP | Descriptor: | CalE8 | Authors: | Lim, J, Yang, D, Liang, Z.X, Kong, R, Murugan, E, Ho, C.L. | Deposit date: | 2011-02-08 | Release date: | 2011-06-15 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution structures of the acyl carrier protein domain from the highly reducing type I iterative polyketide synthase CalE8 Plos One, 6, 2011
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2M27
| Major G-quadruplex structure formed in human VEGF promoter, a monomeric parallel-stranded quadruplex | Descriptor: | DNA_(5'-D(*CP*GP*GP*GP*GP*CP*GP*GP*GP*CP*CP*TP*TP*GP*GP*GP*CP*GP*GP*GP*GP*T)-3')_ | Authors: | Agrawal, P, Hatzakis, E, Guo, K, Carver, M, Yang, D. | Deposit date: | 2012-12-14 | Release date: | 2013-09-18 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution structure of the major G-quadruplex formed in the human VEGF promoter in K+: insights into loop interactions of the parallel G-quadruplexes. Nucleic Acids Res., 41, 2013
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2M6Z
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7KBV
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7KBW
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7KBX
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6JJ0
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6KLM
| NMR solution structure of Roseltide rT7 | Descriptor: | Roseltide rT7 | Authors: | Fan, J.S, Kam, A, Loo, S, Yang, D, Tam, P.J. | Deposit date: | 2019-07-30 | Release date: | 2019-11-20 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Roseltide rT7 is a disulfide-rich, anionic, and cell-penetrating peptide that inhibits proteasomal degradation. J.Biol.Chem., 294, 2019
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4JCM
| Crystal structure of Gamma-CGTASE from Alkalophilic bacillus clarkii at 1.65 Angstrom resolution | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ... | Authors: | Wu, L, Yang, D, Zhou, J, Wu, J, Chen, J. | Deposit date: | 2013-02-22 | Release date: | 2014-02-26 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | The Crystal Structure of Gamma-Cgtase from Alkalophilic Bacillus Clarkii at 1.65 Angstrom Resolution. To be Published
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4KI8
| Crystal structure of a GroEL-ADP complex in the relaxed allosteric state | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, ... | Authors: | Fei, X, Yang, D, LaRonde-LeBlanc, N, Lorimer, G.H. | Deposit date: | 2013-05-01 | Release date: | 2013-07-17 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.722 Å) | Cite: | Crystal structure of a GroEL-ADP complex in the relaxed allosteric state at 2.7 A resolution. Proc.Natl.Acad.Sci.USA, 110, 2013
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7F8Y
| Crystal structure of the cholecystokinin receptor CCKAR in complex with devazepide | Descriptor: | N-[(3S)-1-methyl-2-oxidanylidene-5-phenyl-3H-1,4-benzodiazepin-3-yl]-1H-indole-2-carboxamide, fusion protein of Cholecystokinin receptor type A and Endolysin | Authors: | Zhang, X, He, C, Wang, M, Zhou, Q, Yang, D, Zhu, Y, Wu, B, Zhao, Q. | Deposit date: | 2021-07-02 | Release date: | 2021-10-13 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structures of the human cholecystokinin receptors bound to agonists and antagonists. Nat.Chem.Biol., 17, 2021
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7F8V
| Cryo-EM structure of the cholecystokinin receptor CCKBR in complex with gastrin-17 and Gi | Descriptor: | Gastrin-17, Gastrin/cholecystokinin type B receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Zhang, X, He, C, Wang, M, Zhou, Q, Yang, D, Zhu, Y, Wu, B, Zhao, Q. | Deposit date: | 2021-07-02 | Release date: | 2021-10-13 | Last modified: | 2022-02-16 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structures of the human cholecystokinin receptors bound to agonists and antagonists. Nat.Chem.Biol., 17, 2021
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7F8U
| Crystal structure of the cholecystokinin receptor CCKAR in complex with lintitript | Descriptor: | 2-[2-[[4-(2-chlorophenyl)-1,3-thiazol-2-yl]carbamoyl]indol-1-yl]ethanoic acid, Fusion protein of Cholecystokinin receptor type A and Endolysin | Authors: | Zhang, X, He, C, Wang, M, Zhou, Q, Yang, D, Zhu, Y, Wu, B, Zhao, Q. | Deposit date: | 2021-07-02 | Release date: | 2021-10-13 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structures of the human cholecystokinin receptors bound to agonists and antagonists. Nat.Chem.Biol., 17, 2021
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7F8W
| Cryo-EM structure of the cholecystokinin receptor CCKBR in complex with gastrin-17 and Gq | Descriptor: | Gastrin-17, Gastrin/cholecystokinin type B receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Zhang, X, He, C, Wang, M, Zhou, Q, Yang, D, Zhu, Y, Wu, B, Zhao, Q. | Deposit date: | 2021-07-02 | Release date: | 2021-10-13 | Last modified: | 2022-02-16 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structures of the human cholecystokinin receptors bound to agonists and antagonists. Nat.Chem.Biol., 17, 2021
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7F8X
| Crystal structure of the cholecystokinin receptor CCKAR in complex with NN9056 | Descriptor: | ASP-SMF-NLE-GLY-TRP-NLE-OEM-MEA-NH2 (NN9056), Cholecystokinin receptor type A,Endolysin | Authors: | Zhang, X, He, C, Wang, M, Zhou, Q, Yang, D, Zhu, Y, Wu, B, Zhao, Q. | Deposit date: | 2021-07-02 | Release date: | 2021-12-29 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structures of the human cholecystokinin receptors bound to agonists and antagonists. Nat.Chem.Biol., 17, 2021
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7WGW
| NMR Solution Structure of a cGMP Fill-in Vacancy G-quadruplex Formed in the Oxidized BLM Gene Promoter | Descriptor: | CYCLIC GUANOSINE MONOPHOSPHATE, DNA (20-MER) | Authors: | Wang, K.B, Liu, Y, Li, Y, Li, J, Dickerhoff, J, Yang, M.H, Yang, D, Kong, L.Y. | Deposit date: | 2021-12-29 | Release date: | 2022-05-18 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Oxidative Damage Induces a Vacancy G-Quadruplex That Binds Guanine Metabolites: Solution Structure of a cGMP Fill-in Vacancy G-Quadruplex in the Oxidized BLM Gene Promoter. J.Am.Chem.Soc., 144, 2022
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7F55
| Cryo-EM structure of bremelanotide-MC4R-Gs_Nb35 complex | Descriptor: | CALCIUM ION, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Zhang, H, Chen, L, Mao, C, Shen, Q, Yang, D, Shen, D, Qin, J. | Deposit date: | 2021-06-21 | Release date: | 2021-11-03 | Last modified: | 2022-02-16 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural insights into ligand recognition and activation of the melanocortin-4 receptor. Cell Res., 31, 2021
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7F54
| Cryo-EM structure of afamelanotide-MC4R-Gs_Nb35 complex | Descriptor: | CALCIUM ION, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Zhang, H, Chen, L, Mao, C, Shen, Q, Yang, D, Shen, D, Qin, J. | Deposit date: | 2021-06-21 | Release date: | 2021-11-03 | Last modified: | 2022-02-16 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural insights into ligand recognition and activation of the melanocortin-4 receptor. Cell Res., 31, 2021
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7F53
| Cryo-EM structure of a-MSH-MC4R-Gs_Nb35 complex | Descriptor: | CALCIUM ION, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Zhang, H, Chen, L, Mao, C, Shen, Q, Yang, D, Shen, D, Qin, J. | Deposit date: | 2021-06-21 | Release date: | 2021-11-03 | Last modified: | 2022-02-16 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural insights into ligand recognition and activation of the melanocortin-4 receptor. Cell Res., 31, 2021
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