3J27
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![BU of 3j27 by Molmil](/molmil-images/mine/3j27) | CryoEM structure of Dengue virus | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope protein E, ... | Authors: | Zhang, X, Ge, P, Yu, X, Brannan, J.M, Bi, G, Zhang, Q, Schein, S, Zhou, Z.H. | Deposit date: | 2012-09-26 | Release date: | 2012-12-19 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Cryo-EM structure of the mature dengue virus at 3.5-A resolution. Nat.Struct.Mol.Biol., 20, 2012
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5K3J
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![BU of 5k3j by Molmil](/molmil-images/mine/5k3j) | Crystals structure of Acyl-CoA oxidase-2 in Caenorhabditis elegans bound with FAD, ascaroside-CoA, and ATP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Acyl-coenzyme A oxidase, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Zhang, X, Li, K, Jones, R.A, Bruner, S.D, Butcher, R.A. | Deposit date: | 2016-05-19 | Release date: | 2016-08-24 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.68 Å) | Cite: | Structural characterization of acyl-CoA oxidases reveals a direct link between pheromone biosynthesis and metabolic state in Caenorhabditis elegans. Proc.Natl.Acad.Sci.USA, 113, 2016
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3IYK
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![BU of 3iyk by Molmil](/molmil-images/mine/3iyk) | Bluetongue virus structure reveals a sialic acid binding domain, amphipathic helices and a central coiled coil in the outer capsid proteins | Descriptor: | 2-O-methyl-5-N-acetyl-alpha-D-neuraminic acid, VP2, VP5 | Authors: | Zhang, X, Boyce, M, Bhattacharya, B, Zhang, X, Schein, S, Roy, P, Zhou, Z.H. | Deposit date: | 2010-01-25 | Release date: | 2010-04-07 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (7 Å) | Cite: | Bluetongue virus coat protein VP2 contains sialic acid-binding domains, and VP5 resembles enveloped virus fusion proteins. Proc.Natl.Acad.Sci.USA, 107, 2010
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3J2P
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![BU of 3j2p by Molmil](/molmil-images/mine/3j2p) | CryoEM structure of Dengue virus envelope protein heterotetramer | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope protein E, ... | Authors: | Zhang, X, Ge, P, Yu, X, Brannan, J.M, Bi, G, Zhang, Q, Schein, S, Zhou, Z.H. | Deposit date: | 2012-11-30 | Release date: | 2012-12-19 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Cryo-EM structure of the mature dengue virus at 3.5-A resolution. Nat.Struct.Mol.Biol., 20, 2012
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1D0R
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![BU of 1d0r by Molmil](/molmil-images/mine/1d0r) | |
1CDZ
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![BU of 1cdz by Molmil](/molmil-images/mine/1cdz) | BRCT DOMAIN FROM DNA-REPAIR PROTEIN XRCC1 | Descriptor: | PROTEIN (DNA-REPAIR PROTEIN XRCC1) | Authors: | Zhang, X, Morera, S, Bates, P, Whitehead, P, Coffer, A, Hainbucher, K, Nash, R, Sternberg, M, Lindahl, T, Freemont, P. | Deposit date: | 1999-03-04 | Release date: | 2000-02-28 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structure of an XRCC1 BRCT domain: a new protein-protein interaction module. EMBO J., 17, 1998
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1CFA
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![BU of 1cfa by Molmil](/molmil-images/mine/1cfa) | SOLUTION STRUCTURE OF A SEMI-SYNTHETIC C5A RECEPTOR ANTAGONIST AT PH 5.2, 303K, NMR, 20 STRUCTURES | Descriptor: | COMPLEMENT 5A SEMI-SYNTHETIC ANTAGONIST, SYNTHETIC N-TERMINAL TAIL | Authors: | Zhang, X, Boyar, W, Galakatos, N, Gonnella, N.C. | Deposit date: | 1996-09-21 | Release date: | 1997-09-17 | Last modified: | 2024-06-05 | Method: | SOLUTION NMR | Cite: | Solution structure of a unique C5a semi-synthetic antagonist: implications in receptor binding. Protein Sci., 6, 1997
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1E32
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![BU of 1e32 by Molmil](/molmil-images/mine/1e32) | Structure of the N-Terminal domain and the D1 AAA domain of membrane fusion ATPase p97 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, P97 | Authors: | Zhang, X, Shaw, A, Bates, P.A, Gorman, M.A, Kondo, H, Dokurno, P, Leonard M, G, Sternberg, J.E, Freemont, P.S. | Deposit date: | 2000-06-05 | Release date: | 2001-05-31 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structure of the Aaa ATPase P97 Mol.Cell, 6, 2000
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1EUB
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![BU of 1eub by Molmil](/molmil-images/mine/1eub) | SOLUTION STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN COLLAGENASE-3 (MMP-13) COMPLEXED TO A POTENT NON-PEPTIDIC SULFONAMIDE INHIBITOR | Descriptor: | 1-METHYLOXY-4-SULFONE-BENZENE, 3-METHYLPYRIDINE, CALCIUM ION, ... | Authors: | Zhang, X, Gonnella, N.C, Koehn, J, Pathak, N, Ganu, V, Melton, R, Parker, D, Hu, S.I, Nam, K.Y. | Deposit date: | 2000-04-14 | Release date: | 2001-04-14 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of the catalytic domain of human collagenase-3 (MMP-13) complexed to a potent non-peptidic sulfonamide inhibitor: binding comparison with stromelysin-1 and collagenase-1. J.Mol.Biol., 301, 2000
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5XJC
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![BU of 5xjc by Molmil](/molmil-images/mine/5xjc) | Cryo-EM structure of the human spliceosome just prior to exon ligation at 3.6 angstrom | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ... | Authors: | Zhang, X, Yan, C, Hang, J, Finci, I.L, Lei, J, Shi, Y. | Deposit date: | 2017-04-30 | Release date: | 2017-07-05 | Last modified: | 2020-10-14 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | An Atomic Structure of the Human Spliceosome Cell, 169, 2017
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6ID1
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![BU of 6id1 by Molmil](/molmil-images/mine/6id1) | Cryo-EM structure of a human intron lariat spliceosome after Prp43 loaded (ILS2 complex) at 2.9 angstrom resolution | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, CWF19-like protein 2, Cell division cycle 5-like protein, ... | Authors: | Zhang, X, Zhan, X, Yan, C, Shi, Y. | Deposit date: | 2018-09-07 | Release date: | 2019-03-13 | Last modified: | 2020-10-14 | Method: | ELECTRON MICROSCOPY (2.86 Å) | Cite: | Structures of the human spliceosomes before and after release of the ligated exon. Cell Res., 29, 2019
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3J9D
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![BU of 3j9d by Molmil](/molmil-images/mine/3j9d) | Atomic structure of a non-enveloped virus reveals pH sensors for a coordinated process of cell entry | Descriptor: | Outer capsid protein VP2, ZINC ION | Authors: | Zhang, X, Patel, A, Celma, C, Roy, P, Zhou, Z.H. | Deposit date: | 2015-01-09 | Release date: | 2015-12-09 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Atomic model of a nonenveloped virus reveals pH sensors for a coordinated process of cell entry. Nat.Struct.Mol.Biol., 23, 2016
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3J9E
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![BU of 3j9e by Molmil](/molmil-images/mine/3j9e) | Atomic structure of a non-enveloped virus reveals pH sensors for a coordinated process of cell entry | Descriptor: | VP5 | Authors: | Zhang, X, Patel, A, Celma, C, Roy, P, Zhou, Z.H. | Deposit date: | 2015-01-10 | Release date: | 2015-12-09 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Atomic model of a nonenveloped virus reveals pH sensors for a coordinated process of cell entry. Nat.Struct.Mol.Biol., 23, 2016
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6ID0
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![BU of 6id0 by Molmil](/molmil-images/mine/6id0) | Cryo-EM structure of a human intron lariat spliceosome prior to Prp43 loaded (ILS1 complex) at 2.9 angstrom resolution | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, CWF19-like protein 2, Cell division cycle 5-like protein, ... | Authors: | Zhang, X, Zhan, X, Yan, C, Shi, Y. | Deposit date: | 2018-09-07 | Release date: | 2019-03-13 | Last modified: | 2020-10-14 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structures of the human spliceosomes before and after release of the ligated exon. Cell Res., 29, 2019
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6ICZ
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![BU of 6icz by Molmil](/molmil-images/mine/6icz) | Cryo-EM structure of a human post-catalytic spliceosome (P complex) at 3.0 angstrom | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... | Authors: | Zhang, X, Zhan, X, Yan, C, Shi, Y. | Deposit date: | 2018-09-07 | Release date: | 2019-03-13 | Last modified: | 2020-10-14 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structures of the human spliceosomes before and after release of the ligated exon. Cell Res., 29, 2019
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2GS7
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![BU of 2gs7 by Molmil](/molmil-images/mine/2gs7) | Crystal Structure of the inactive EGFR kinase domain in complex with AMP-PNP | Descriptor: | Epidermal growth factor receptor, IODIDE ION, MAGNESIUM ION, ... | Authors: | Zhang, X, Gureasko, J, Shen, K, Cole, P.A, Kuriyan, J. | Deposit date: | 2006-04-25 | Release date: | 2006-06-20 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | An allosteric mechanism for activation of the kinase domain of epidermal growth factor receptor Cell(Cambridge,Mass.), 125, 2006
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2GS2
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![BU of 2gs2 by Molmil](/molmil-images/mine/2gs2) | Crystal Structure of the active EGFR kinase domain | Descriptor: | Epidermal growth factor receptor | Authors: | Zhang, X, Gureasko, J, Shen, K, Cole, P.A, Kuriyan, J. | Deposit date: | 2006-04-25 | Release date: | 2006-06-20 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | An allosteric mechanism for activation of the kinase domain of epidermal growth factor receptor. Cell(Cambridge,Mass.), 125, 2006
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4DXW
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![BU of 4dxw by Molmil](/molmil-images/mine/4dxw) | Crystal structure of NavRh, a voltage-gated sodium channel | Descriptor: | 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CALCIUM ION, Ion transport protein, ... | Authors: | Zhang, X, Ren, W.L, Yan, C.Y, Wang, J.W, Yan, N. | Deposit date: | 2012-02-28 | Release date: | 2012-05-23 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (3.052 Å) | Cite: | Crystal structure of an orthologue of the NaChBac voltage-gated sodium channel Nature, 486, 2012
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3J8G
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![BU of 3j8g by Molmil](/molmil-images/mine/3j8g) | Electron cryo-microscopy structure of EngA bound with the 50S ribosomal subunit | Descriptor: | 23S rRNA, 50S ribosomal protein L1, 50S ribosomal protein L11, ... | Authors: | Zhang, X, Yan, K, Zhang, Y, Li, N, Ma, C, Li, Z, Zhang, Y, Feng, B, Liu, J, Sun, Y, Xu, Y, Lei, J, Gao, N. | Deposit date: | 2014-10-24 | Release date: | 2014-11-26 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (5 Å) | Cite: | Structural insights into the function of a unique tandem GTPase EngA in bacterial ribosome assembly Nucleic Acids Res., 2014
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7VPX
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![BU of 7vpx by Molmil](/molmil-images/mine/7vpx) | The cryo-EM structure of the human pre-A complex | Descriptor: | 5SS, DnaJ homolog subfamily C member 8, PHD finger-like domain-containing protein 5A, ... | Authors: | Zhang, X, Zhan, X, Shi, Y. | Deposit date: | 2021-10-18 | Release date: | 2023-05-03 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural insights into branch site proofreading by human spliceosome. Nat.Struct.Mol.Biol., 2024
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3KL1
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![BU of 3kl1 by Molmil](/molmil-images/mine/3kl1) | |
2Y3A
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![BU of 2y3a by Molmil](/molmil-images/mine/2y3a) | Crystal structure of p110beta in complex with icSH2 of p85beta and the drug GDC-0941 | Descriptor: | 2-(1H-indazol-4-yl)-6-{[4-(methylsulfonyl)piperazin-1-yl]methyl}-4-morpholin-4-yl-thieno[3,2-d]pyrimidine, PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT BETA, PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT BETA ISOFORM | Authors: | Zhang, X, Vadas, O, Perisic, O, Williams, R.L. | Deposit date: | 2010-12-20 | Release date: | 2011-03-16 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structure of Lipid Kinase P110Beta-P85Beta Elucidates an Unusual Sh2-Domain-Mediated Inhibitory Mechanism. Mol.Cell, 41, 2011
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3KLX
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![BU of 3klx by Molmil](/molmil-images/mine/3klx) | |
3IYL
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![BU of 3iyl by Molmil](/molmil-images/mine/3iyl) | Atomic CryoEM Structure of a Nonenveloped Virus Suggests How Membrane Penetration Protein is Primed for Cell Entry | Descriptor: | Core protein VP6, MYRISTIC ACID, Outer capsid VP4, ... | Authors: | Zhang, X, Jin, L, Fang, Q, Hui, W, Zhou, Z.H. | Deposit date: | 2010-02-02 | Release date: | 2010-05-12 | Last modified: | 2018-07-18 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | 3.3 A cryo-EM structure of a nonenveloped virus reveals a priming mechanism for cell entry. Cell(Cambridge,Mass.), 141, 2010
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1AIY
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![BU of 1aiy by Molmil](/molmil-images/mine/1aiy) | R6 HUMAN INSULIN HEXAMER (SYMMETRIC), NMR, 10 STRUCTURES | Descriptor: | PHENOL, R6 INSULIN HEXAMER, ZINC ION | Authors: | Chang, X, Jorgensen, A.M.M, Bardrum, P, Led, J.J. | Deposit date: | 1997-04-30 | Release date: | 1997-11-12 | Last modified: | 2022-02-16 | Method: | SOLUTION NMR | Cite: | Solution structures of the R6 human insulin hexamer. Biochemistry, 36, 1997
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